ketoconazole and acridines

ketoconazole has been researched along with acridines in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borchardt, RT; Jin, JY; Mudra, DR	1
Croubels, S; Gadeyne, C; Gasthuys, F; Polis, I; Schauvliege, S; Van der Heyden, S	1
Ahmed, Z; Bentz, J; Ellens, H; Hidalgo, IJ; Li, J; Li, L; Lumen, AA; Meng, Z; Owen, A	1

Trials

1 trial(s) available for ketoconazole and acridines

Article	Year
The influence of modulation of P-glycoprotein and /or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs. Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:5 Topics: Absorption; Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Enzyme Inhibitors; Female; Ketoconazole; Male; Morphine; Rifampin; Tetrahydroisoquinolines	2011

Article

Year

The influence of modulation of P-glycoprotein and /or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs.

Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:5

Topics: Absorption; Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Enzyme Inhibitors; Female; Ketoconazole; Male; Morphine; Rifampin; Tetrahydroisoquinolines

2011

Other Studies

2 other study(ies) available for ketoconazole and acridines

Article	Year
Absorption barriers in the rat intestinal mucosa: 2. Application of physiologically based mathematical models to quantify mechanisms of drug permeation and metabolism. Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:2 Topics: Acridines; Adrenergic beta-Antagonists; Algorithms; Animals; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Computer Simulation; Cyclosporins; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Intestinal Absorption; Intestinal Mucosa; Ketoconazole; Models, Statistical; Pharmaceutical Preparations; Rats; Tetrahydroisoquinolines; Verapamil	2010
Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. PloS one, 2013, Volume: 8, Issue:8 Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Cyclosporine; Digoxin; Dogs; Furans; Gene Expression; Humans; Ketoconazole; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Protein Binding; Quinidine; Sulfonamides; Tetrahydroisoquinolines; Vinblastine	2013

Article

Year

Absorption barriers in the rat intestinal mucosa: 2. Application of physiologically based mathematical models to quantify mechanisms of drug permeation and metabolism.

Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:2

Topics: Acridines; Adrenergic beta-Antagonists; Algorithms; Animals; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Computer Simulation; Cyclosporins; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Intestinal Absorption; Intestinal Mucosa; Ketoconazole; Models, Statistical; Pharmaceutical Preparations; Rats; Tetrahydroisoquinolines; Verapamil

2010

Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.

PloS one, 2013, Volume: 8, Issue:8

Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Cyclosporine; Digoxin; Dogs; Furans; Gene Expression; Humans; Ketoconazole; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Protein Binding; Quinidine; Sulfonamides; Tetrahydroisoquinolines; Vinblastine

2013