Compounds > ketoconazole

ketoconazole and 3-methylcholanthrene

ketoconazole has been researched along with 3-methylcholanthrene in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Carazo, A; Drechslerová, M; Hrušková, ZR; Hyrsova, L; Kuneš, J; Nova, A; Pavek, P; Pour, M; Smutny, T; Špulák, M1
Klahr, S; Reyes, AA1
Hsieh, CY; Huang, JD1
Gorman, N; Lambrecht, RW; Sinclair, JF; Sinclair, PR1
Jacobs, JM; Lambrecht, RW; Sinclair, JF; Sinclair, PR1
Heykants, J; Lavrijsen, K; Meuldermans, W; Thijs, D; van Houdt, J1
Horsmans, Y; Spatzenegger, M; Verbeeck, RK1
Hurh, E; Kim, S; Kim, Y; Lee, A; Lee, E; Lee, M1

Other Studies

10 other study(ies) available for ketoconazole and 3-methylcholanthrene

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
    Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10

    Topics: Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hep G2 Cells; Hepatocytes; Humans; Models, Molecular; Molecular Structure; Quinazolines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2016
Cytochrome P-450 pathway in renal function of normal rats and rats with bilateral ureteral obstruction.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 201, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blood Pressure; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Glomerular Filtration Rate; Hemodynamics; Ketoconazole; Kidney; Kidney Cortex; Methylcholanthrene; Microsomes; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

1992
Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism.
    Journal of chromatography, 1992, Mar-13, Volume: 575, Issue:1

    Topics: Acetone; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cimetidine; Dexamethasone; Diazepam; Enzyme Induction; Female; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Safrole; Sex Characteristics; Stereoisomerism; Sulfaphenazole

1992
Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2.
    Archives of biochemistry and biophysics, 1992, May-01, Volume: 294, Issue:2

    Topics: Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Ketoconazole; Kinetics; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Quinolines; Uroporphyrinogens

1992
Inhibition of uroporphyrinogen decarboxylase activity. The role of cytochrome P-450-mediated uroporphyrinogen oxidation.
    The Biochemical journal, 1990, Jul-15, Volume: 269, Issue:2

    Topics: Animals; Carboxy-Lyases; Chick Embryo; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ketoconazole; Kinetics; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; NADP; Oxidation-Reduction; Polychlorinated Biphenyls; Porphyrinogens; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

1990
Interaction of miconazole, ketoconazole and itraconazole with rat-liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:1

    Topics: Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme Inhibitors; Itraconazole; Ketoconazole; Kinetics; Male; Methylcholanthrene; Miconazole; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Rats

1987
Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:2

    Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Induction; Enzyme Inhibitors; Injections, Intraperitoneal; Intestine, Small; Ketoconazole; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Wistar; Theobromine; Theophylline

2000
Effects of enzyme inducers or inhibitors on the pharmacokinetics of intravenous parathion in rats.
    Biopharmaceutics & drug disposition, 2000, Volume: 21, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Insecticides; Isoenzymes; Isoniazid; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Paraoxon; Parathion; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Tissue Distribution

2000