ketoconazole has been researched along with 3-hydroxyquinidine in 7 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 4 (57.14) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ishizaki, T; Kawashiro, T; Zhao, XJ | 1 |
Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA; Westerberg, PA | 1 |
Bhoopathy, S; Karnes, HT; Sarkar, MA | 1 |
Bertilsson, L; Ericsson, O; Gustafsson, LL; Mirghani, RA; Tybring, G | 1 |
Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA | 1 |
Allqvist, A; Bertilsson, L; Mirghani, RA; Miura, J | 1 |
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M; van de Steeg, E | 1 |
3 trial(s) available for ketoconazole and 3-hydroxyquinidine
Article | Year |
---|---|
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo.
Topics: Adult; Antifungal Agents; Antimalarials; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fluvoxamine; Humans; Hydroxylation; Ketoconazole; Male; Mixed Function Oxygenases; Quinidine; Quinine; Selective Serotonin Reuptake Inhibitors | 1999 |
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.
Topics: Adult; Biomarkers; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Male; Middle Aged; Quinidine; Quinine | 2003 |
Metabolism and elimination of quinine in healthy volunteers.
Topics: Antimalarials; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Mixed Function Oxygenases; Quinidine; Quinine; Quinones; Time Factors | 2003 |
4 other study(ies) available for ketoconazole and 3-hydroxyquinidine
Article | Year |
---|---|
Mutual inhibition between quinine and etoposide by human liver microsomes. Evidence for cytochrome P4503A4 involvement in their major metabolic pathways.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Etoposide; Humans; Ketoconazole; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Quinidine; Quinine; Troleandomycin | 1998 |
Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Cytochrome P-450 CYP3A; Electrophoresis, Capillary; Enzyme Inhibitors; Erythromycin; Fluconazole; Hydroxylation; Ketoconazole; Microsomes, Liver; Oxidoreductases, N-Demethylating; Quinidine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 2002 |
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.
Topics: Alprazolam; Anti-Anxiety Agents; Antifungal Agents; Antimalarials; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Humans; Inhibitory Concentration 50; Ketoconazole; Mass Spectrometry; Microsomes, Liver; Quinidine; Stereoisomerism | 2007 |
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil | 2017 |