ketoconazole and 25-hydroxycholesterol

ketoconazole has been researched along with 25-hydroxycholesterol in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Hashimoto, Y; Ohgane, K; Sagimori, I; Yoshioka, H1
Davis, RA; Dueland, S; Leighton, JK; Straka, MS; Trawick, J1
Panini, SR; Schnitzer-Polokoff, R; Sinensky, M; Spencer, TA1
Alvarez, JG; Favata, MF; Strauss, JF; Takagi, K; Trzaskos, JM1
Carlstrom, AJ; Deikman, J; Ellsworth, JL1
Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ1
Aikawa, K; Arai, H; Fujimoto, Y; Furuchi, T; Ikemoto, M; Inoue, K; Sato, Y1
Guan, JZ; Matsui, J; Murakami, H; Suda, T; Tamasawa, N; Yamato, K1

Other Studies

8 other study(ies) available for ketoconazole and 25-hydroxycholesterol

ArticleYear
Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.
    Bioorganic & medicinal chemistry, 2020, 02-01, Volume: 28, Issue:3

    Topics: HEK293 Cells; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Molecular Structure; Oxysterols; Sterol Regulatory Element Binding Proteins; Structure-Activity Relationship

2020
Activation of the silent endogenous cholesterol-7-alpha-hydroxylase gene in rat hepatoma cells: a new complementation group having resistance to 25-hydroxycholesterol.
    Molecular and cellular biology, 1991, Volume: 11, Issue:4

    Topics: Animals; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Dexamethasone; Drug Resistance; Gene Expression Regulation; Genes; Genetic Complementation Test; Hydroxycholesterols; Ketoconazole; Lipoproteins, LDL; Liver Neoplasms, Experimental; Microsomes, Liver; Rats; RNA, Messenger; Transfection; Tumor Cells, Cultured

1991
Sterol-independent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by mevalonate in Chinese hamster ovary cells. Magnitude and specificity.
    The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19

    Topics: Acetyl-CoA C-Acetyltransferase; Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Dose-Response Relationship, Drug; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Synthase; Ketoconazole; Lanosterol; Mevalonic Acid; Naphthols; Squalene; Sterols

1989
Control of low density lipoprotein receptor gene promoter activity. Ketoconazole inhibits serum lipoprotein but not oxysterol suppression of gene transcription.
    The Journal of biological chemistry, 1989, Jul-25, Volume: 264, Issue:21

    Topics: Cell Line; Cloning, Molecular; Culture Media; Gene Expression Regulation; Genes; Humans; Hydroxycholesterols; Ketoconazole; Kinetics; Lipoproteins; Promoter Regions, Genetic; Receptors, LDL; Suppression, Genetic; Transcription, Genetic; Tumor Cells, Cultured

1989
Ketoconazole and 25-hydroxycholesterol produce reciprocal changes in the rate of transcription of the human LDL receptor gene.
    Biochimica et biophysica acta, 1994, Jan-20, Volume: 1210, Issue:3

    Topics: Base Sequence; Humans; Hydroxycholesterols; Ketoconazole; Molecular Sequence Data; Receptors, LDL; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1994
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E

1993
Inhibition of cholesteryl ester formation in macrophages by azole antimycotics.
    Biochemical pharmacology, 1999, Aug-01, Volume: 58, Issue:3

    Topics: Animals; Antifungal Agents; Azoles; Cells, Cultured; Cholesterol; Cholesterol Esters; Econazole; Endocytosis; Esterification; Female; Hydroxycholesterols; Ketoconazole; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Miconazole

1999
Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.
    The Tohoku journal of experimental medicine, 2003, Volume: 201, Issue:4

    Topics: Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Northern; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Drug Therapy, Combination; Hydroxycholesterols; Ketoconazole; Lipid Metabolism; Lipoproteins; Liver X Receptors; Male; Microsomes, Liver; Orphan Nuclear Receptors; Peroxisome Proliferators; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA; RNA, Messenger; Steroids; Transcription Factors; Up-Regulation

2003