ketoconazole has been researched along with 17-alpha-hydroxyprogesterone in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (44.44) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Kühn-Velten, WN; Lessmann, M | 1 |
| Adelmann, B; Engelhardt, D; Weber, MM; Will, A | 1 |
| Conget, JI; Ferrer, J; González-Clemente, JM; Halperin, I; Martinez-Osaba, MJ; Vilardell, E | 1 |
| Brenner, SH; Gabrilove, JL; Pepper, G | 1 |
| Bhansali, A; Dash, RJ; Khandekar, S; Lata, V | 2 |
| Knuth, UA; Nashan, D; Nieschlag, E; Weidinger, G | 1 |
| Amery, W; Beerens, D; Caers, I; Coene, MC; De Coster, R; Haelterman, C | 1 |
| Trachtenberg, J; Zadra, J | 1 |
| Aste, N; Lecca, U; Marcello, C; Medda, F; Parodo, G; Pascalis, P; Pia, G; Puligheddu, P | 1 |
| Cantwell, BM; Dowsett, M; Harris, AL | 1 |
| Bailey, JD; Fazekas, AT; Fishman, L; Holland, FJ | 1 |
| Dörr, G; Engelhardt, D; Jaspers, C; Knorr, D | 1 |
| McDonald, R; Nachreiner, R; Roudebush, P; Willard, MD | 1 |
| Bons, EG; Bruining, HA; de Jong, FH; Lamberts, SW | 1 |
| Goshima, E; Hirai, M; Miura, K; Murase, H; Murayama, M; Noritake, N; Takeda, N; Yamakita, N; Yasuda, K | 1 |
| Glass, AR | 1 |
| Beerens, D; De Coster, R; Dom, J; Willemsens, G | 1 |
| Algur, N; Barr, I; Boldes, R; Diamant, YZ; Gal, M; Orly, J | 1 |
| Estabrook, RW; Mason, JI; Swart, AC; Swart, P; Waterman, MR | 1 |
| Adair, CD; Esplin, MS; Graves, SW; Ma, J; Mason, LA | 1 |
| Arlt, W; de Herder, WW; de Jong, FH; Feelders, RA; Hofland, J; Hofland, LJ; Steenbergen, J; Taylor, AE; van der Pas, R; van Koetsveld, PM | 1 |
| Blázquez, M; Dimastrogiovanni, G; Fernandes, D; Porte, C | 1 |
| Amory, JK; Anawalt, BD; Bremner, WJ; Lin, K; Marck, BT; Matsumoto, AM; Nya-Ngatchou, JJ; Page, ST; Roth, MY | 1 |
2 trial(s) available for ketoconazole and 17-alpha-hydroxyprogesterone
| Article | Year |
|---|---|
The antimycotic drug terbinafine in contrast to ketoconazole lacks acute effects on the pituitary-testicular function of healthy men: a placebo-controlled double-blind trial.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Antifungal Agents; Clinical Trials as Topic; Double-Blind Method; Estradiol; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Male; Naphthalenes; Pituitary Gland; Placebos; Terbinafine; Testis; Testosterone | 1989 |
Androgen synthesis in the gonadotropin-suppressed human testes can be markedly suppressed by ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androgens; Androstenedione; Contraception; Dehydroepiandrosterone; Drug Design; Drug Synergism; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Middle Aged; Oligopeptides; Placebos; Spermatogenesis; Testis; Testosterone; Young Adult | 2013 |
25 other study(ies) available for ketoconazole and 17-alpha-hydroxyprogesterone
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Ketoconazole inhibition of the bifunctional cytochrome P450c17 does not affect androgen formation from the endogenous lyase substrate. The catalytic site remains refractory in the course of intermediary hydroxyprogesterone processing.
Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androgens; Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Hydroxyprogesterones; Intracellular Membranes; Ketoconazole; Male; Progesterone; Rats; Rats, Wistar; Steroid 17-alpha-Hydroxylase; Testis | 1992 |
Effect of ketoconazole on human ovarian C17,20-desmolase and aromatase.
Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androstenedione; Aromatase; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Female; Granulosa Cells; Humans; Hydroxyprogesterones; Ketoconazole; Ovary; Steroid 17-alpha-Hydroxylase | 1991 |
Evaluation of clinical and hormonal effects in hirsute women treated with ketoconazole.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydroxyprogesterones; Ketoconazole; Testosterone | 1990 |
Ketoconazole use in the treatment of ovarian hyperandrogenism.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androgens; Estradiol; Female; Follicle Stimulating Hormone; Hair; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Menstruation; Ovarian Diseases; Ovary; Pituitary Hormone-Releasing Hormones; Sex Hormone-Binding Globulin; Testosterone | 1990 |
Ketoconazole in the treatment of Cushing's disease.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Cushing Syndrome; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Middle Aged; Testosterone; Time Factors | 1990 |
Circulating cortisol & related steroids following ketoconazole challenge in Cushing's disease.
Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androstenedione; Cushing Syndrome; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase | 1990 |
Effects of high dose ketoconazole therapy on the main plasma testicular and adrenal steroids in previously untreated prostatic cancer patients.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Androgens; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Testosterone | 1986 |
Steroid synthesis inhibition by ketoconazole: sites of action.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aldehyde-Lyases; Androgens; Androstenedione; Chorionic Gonadotropin; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 1988 |
Short term treatment with ketoconazole: effects on gonadal and adrenal steroidogenesis in women.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Radioimmunoassay; Testosterone | 1987 |
High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Menopause; Middle Aged; Sex Hormone-Binding Globulin; Testosterone | 1988 |
Ketoconazole in the management of precocious puberty not responsive to LHRH-analogue therapy.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Buserelin; Child Behavior; Child, Preschool; Drug Resistance; Follicle Stimulating Hormone; Growth; Humans; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Male; Puberty, Precocious; Testosterone | 1985 |
Ketoconazole blocks cortisol secretion in man by inhibition of adrenal 11 beta-hydroxylase.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Corticosterone; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases | 1985 |
Ketoconazole-induced changes in selected canine hormone concentrations.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Aldosterone; Animals; Cortodoxone; Dogs; Estradiol; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Testosterone | 1986 |
Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Cortodoxone; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Ketoconazole; Metyrapone; Miconazole; Progesterone | 1987 |
Response of plasma adrenal steroids to synthetic ACTH under ketoconazole in man.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldehyde-Lyases; Aldosterone; Corticosterone; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase | 1987 |
Ketoconazole-induced stimulation of gonadotropin output in men: basis for a potential test of gonadotropin reserve.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Male; Testosterone | 1986 |
Endocrinological effects of single daily ketoconazole administration in male beagle dogs.
Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Estradiol; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Male; Progesterone; Testosterone; Time Factors | 1984 |
Low dose ketoconazole attenuates serum androgen levels in patients with polycystic ovary syndrome and inhibits ovarian steroidogenesis in vitro.
Topics: 17-alpha-Hydroxyprogesterone; 17-Hydroxysteroid Dehydrogenases; Administration, Oral; Adrenocorticotropic Hormone; Adult; Androgens; Aromatase; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Estradiol; Female; Granulosa Cells; Humans; Hydroxyprogesterones; In Vitro Techniques; Ketoconazole; Luteal Phase; Ovary; Polycystic Ovary Syndrome; Progesterone; Steroid 17-alpha-Hydroxylase; Testosterone | 1994 |
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line, Transformed; Chlorocebus aethiops; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; DNA; Humans; Hydroxyprogesterones; Ketoconazole; Kidney; Kinetics; Male; Microsomes; NADP; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testis; Transfection | 1993 |
Increasing evidence for and regulation of a human placental endogenous digitalis-like factor.
Topics: 17-alpha-Hydroxyprogesterone; Cardenolides; Female; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Ketoconazole; Placenta; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Saponins; Statistics, Nonparametric | 2012 |
Fluconazole inhibits human adrenocortical steroidogenesis in vitro.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cortodoxone; Desoxycorticosterone; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Pregnenolone; Progesterone | 2012 |
Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).
Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Bass; Benzopyrans; Bile; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Endocrine Disruptors; Fatty Acids, Monounsaturated; Female; Glucuronosyltransferase; Gonads; Inactivation, Metabolic; Ketoconazole; Liver; Male; Water Pollutants, Chemical | 2013 |