ketoconazole and 1-aminobenzotriazole

ketoconazole has been researched along with 1-aminobenzotriazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Karuo, Y; Kataoka, M; Kawai, K; Nakae, M; Okada, J; Omote, M; Sato, K; Tarui, A; Tsujimura, T; Yamashita, S1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Clark, JE; Harder, DR; Kauser, K; Ma, YH; Masters, BS; Ortiz de Montellano, PR; Roman, RJ1
Jain, GK; Manickavasagam, L; Mishra, S1
Greenhaw, J; Salminen, WF; Shi, Q; Yang, X1
Doshi, U; Li, AP1
Brock, B; Ly, VT1
Kubickova, B; Martinkova, M; Stiborova, M1
Fukami, T; Nakajima, M; Oda, S; Takai, S; Tsuneyama, K; Yokoi, T1
Khan, AA; LeDuc, BW; Shaik, AN1

Other Studies

11 other study(ies) available for ketoconazole and 1-aminobenzotriazole

ArticleYear
Discovery of benzyloxyphenyl- and phenethylphenyl-imidazole derivatives as a new class of ante-drug type boosters.
    Bioorganic & medicinal chemistry letters, 2022, 09-15, Volume: 72

    Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Esters; Imidazoles; Nitroimidazoles

2022
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries.
    Circulation research, 1991, Volume: 68, Issue:4

    Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dogs; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Ketoconazole; Kinetics; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylcholine; Proadifen; Renal Artery; Triazoles

1991
Determination of metabolic profile of anti-malarial trioxane CDRI 99/411 in rat liver microsomes using HPLC.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:1

    Topics: Animals; Antimalarials; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Heterocyclic Compounds; Humans; Ketoconazole; Kinetics; Male; Metabolome; Microsomes, Liver; Nonlinear Dynamics; Rats; Rats, Sprague-Dawley; Spiro Compounds; Triazoles

2012
Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2

    Topics: Aniline Compounds; Animals; Benzoflavones; Biomarkers; Cell Survival; Cells, Cultured; Crotonates; Cytochrome P-450 Enzyme System; Hepatocytes; Hydroxybutyrates; Inactivation, Metabolic; Isoxazoles; Ketoconazole; Leflunomide; Liver; Male; Nitriles; Primary Cell Culture; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine; Toluidines; Triazoles

2011
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4.
    Drug metabolism letters, 2011, Volume: 5, Issue:3

    Topics: Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Design; Enzyme Inhibitors; Erythromycin; Female; Hepatocytes; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Ketoconazole; Male; Middle Aged; Time Factors; Triazoles; Young Adult

2011
Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.
    Chemico-biological interactions, 2011, Sep-05, Volume: 193, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Benzopyrans; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucuronides; Glutathione; Hydroxylation; Ketoconazole; L-Lactate Dehydrogenase; Liver; Male; Mass Spectrometry; Molecular Structure; Necrosis; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Tranylcypromine; Triazoles

2011
Effects of cytochrome P450 inhibitors on peroxidase activity.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 3

    Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin

2012
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:1

    Topics: Alanine Transaminase; Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dexamethasone; Gadolinium; Ketoconazole; Kupffer Cells; Male; Mice; Mice, Inbred BALB C; Models, Animal; Triazoles

2016
Characterization of 1-Aminobenzotriazole and Ketoconazole as Novel Inhibitors of Monoamine Oxidase (MAO): An In Vitro Investigation.
    European journal of drug metabolism and pharmacokinetics, 2017, Volume: 42, Issue:5

    Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Kinetics; Liver; Mice; Microsomes, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Triazoles

2017