ketanserin and trazodone

ketanserin has been researched along with trazodone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Alhaider, AA; Mustafa, AA1
Leff, P; Martin, GR1
Freedman, M; Hamel, L; Luttinger, D; Perrone, M; Ward, SJ1
Altuğ, U; Erol, D; Germiyanoğlu, C; Gürdal, M; Kurt, U; Ozkardeş, H1
Giovannini, MG; Pazzagli, M; Pepeu, G1

Trials

1 trial(s) available for ketanserin and trazodone

ArticleYear
The efficacy of anti-serotoninergic agents in the treatment of erectile dysfunction.
    The Journal of urology, 1994, Volume: 152, Issue:2 Pt 1

    Topics: Adult; Aged; Double-Blind Method; Erectile Dysfunction; Humans; Ketanserin; Male; Mianserin; Middle Aged; Trazodone

1994

Other Studies

10 other study(ies) available for ketanserin and trazodone

ArticleYear
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Enhancement of imipramine-induced rat brain beta-adrenoreceptor desensitization by subacute co-administration of trazodone, zimelidine, quipazine or 5-hydroxytryptophan.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Drinking Behavior; Female; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Methysergide; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin Antagonists; Trazodone; Zimeldine

1991
Peripheral 5-HT2-like receptors. Can they be classified with the available antagonists?
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Jugular Veins; Ketanserin; Male; Methysergide; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Trazodone

1986
The effects of serotonin antagonists in a behavioral despair procedure in mice.
    European journal of pharmacology, 1984, Dec-15, Volume: 107, Issue:1

    Topics: Animals; Behavior, Animal; Cyproheptadine; Guinea Pigs; Ketanserin; Male; Methysergide; Mice; Muscle, Smooth; Piperidines; Pizotyline; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Trazodone; Tritium

1984
Trazodone increases extracellular serotonin levels in the frontal cortex of rats.
    European journal of pharmacology, 1999, Nov-03, Volume: 383, Issue:3

    Topics: Animals; Antidepressive Agents, Second-Generation; Carrier Proteins; Cerebral Cortex; Fluoxetine; Ketanserin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Trazodone

1999