ketanserin has been researched along with ritanserin in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (21.43) | 18.7374 |
| 1990's | 74 (52.86) | 18.2507 |
| 2000's | 26 (18.57) | 29.6817 |
| 2010's | 7 (5.00) | 24.3611 |
| 2020's | 3 (2.14) | 2.80 |
| Authors | Studies |
|---|---|
| Kanao, M; Kobayashi, S; Morishima, Y; Shibano, T; Tanaka, T; Usui, H; Watanabe, Y; Yasuoka, M; Yoshiwara, H | 1 |
| Arnt, J; Boeck, V; Bøgesø, KP; Christensen, AV; Hyttel, J; Jensen, KG | 1 |
| Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W | 1 |
| Andersen, K; Bøgesø, KP; Gundertofte, K; Liljefors, T; Perregaard, J | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R | 1 |
| Beleta, J; Doménech, T; Palacios, JM | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Van Gompel, P; Vanhoenacker, P; Wouters, R | 1 |
| Kristiansen, K; Kroeze, WK; Roth, BL; Shapiro, DA | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R | 1 |
| Glennon, RA | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Bielenica, A; Corvino, A; Fiorino, F; Kędzierska, E; Kmiecik, S; Koliński, A; Koliński, M; Kozioł, AE; Magli, E; Massarelli, P; Rossi, I; Sawczenko, A; Severino, B; Struga, M | 1 |
| Baldanzi, G; Bertoni, A; Capello, D; Fresu, LG; Gesu, A; Graziani, A; Massarotti, A; Ruffo, E; Snow, AL; Talmon, M; Tron, GC; Varma, KSS; Velnati, S | 1 |
| Chen, Z; Collier, T; Fu, H; Liang, SH; Rong, J; Zhou, J | 1 |
| Neuman, RS; Zebrowska, G | 1 |
| Furuta, S; Homma, T; Kawa, S; Kobayashi, M; Koiwai, T; Oguchi, H; Terashima, M | 1 |
| Fuji, K; Hiramatsu, M; Kameyama, T; Nabeshima, T; Niwa, K | 1 |
| Chen, HY; Lee, EH; Liang, KC; Lin, WR; Shiu, WH | 1 |
| Dahlgren, IL; Klint, T; Larsson, K | 1 |
| Brazell, C; Campbell, IC; Mitchell, S; Stahl, SM; Twist, EC | 1 |
| Gorzalka, BB; Watson, NV | 1 |
| Hong, E; Meneses, A | 1 |
| Beczkowska, IW; Bodnar, RJ | 1 |
| Gentili, L; Luchetti, G; Massi, M; Saija, A | 1 |
| Hoyer, D; Sahin-Erdemli, I; Schoeffter, P | 1 |
| Nakamura, H; Suzukawa, M | 1 |
| Broekkamp, CL; Jenck, F; Van Delft, AM | 1 |
| Dewar, KM; Lima, L; Reader, TA | 1 |
| Glowinski, J; Godbout, R; Mantz, J; Tassin, JP; Thierry, AM | 1 |
| Cohen, ML; Mann, JJ; McBride, PA; Nimchinsky, E | 1 |
| Geyer, MA; Tapson, GS; Wing, LL | 1 |
| Backus, LI; Grahame-Smith, DG; Sharp, T | 1 |
| Demetrikopoulos, MK; Flaherty, CF; Grigson, PS; Krauss, KL; Rowan, GA; Weaver, MS | 1 |
| Jackson, DA; White, SR | 1 |
| Cowen, PJ; Gartside, SE | 1 |
| Coker, SJ; Ellis, AM | 1 |
| Ball, SG; Robertson, JI; Stott, DJ | 1 |
| Ball, SG; Hosie, J; Robertson, JI; Stott, DJ | 1 |
| Gradin, K; Hedner, T; Persson, B; Pettersson, A | 3 |
| Cohen, ML; Kurz, KD; Schenck, KW | 1 |
| Ramage, AG | 1 |
| Hedner, T; Persson, B | 1 |
| Reneman, RS; van der Starre, PJ | 1 |
| Blauw, GJ; Chang, PC; van Brummelen, P; van Zwieten, PA; Vermeij, P | 1 |
| Lund, N; Thorborg, P | 1 |
| Bloomquist, WL; Cohen, ML; Fuller, RW; Snoddy, HD | 1 |
| Arnt, J; Hyttel, J | 1 |
| Chau, NP; Levenson, J; Pithois-Merli, I; Simon, AC | 1 |
| Alling, C; Hansson, E; Simonsson, P | 1 |
| Gommeren, W; Janssen, PF; Laduron, PM; Leysen, JE; Van Gompel, P; Wynants, J | 1 |
| Batink, HD; Boddeke, E; Doods, HN; Hugtenburg, JG; Korstanje, C; Sprenkels, R; Thoolen, MJ; Van Zwieten, PA | 1 |
| Hedner, T; Persson, B; Pettersson, A | 1 |
| Hewson, G; Hill, RG; Hughes, J; Leighton, GE | 1 |
| Gommeren, W; Janssen, PA; Leysen, JE; Van Gompel, P; Woestenborghs, R | 1 |
| Byrne, JH; Ocorr, KA | 1 |
| Jandhyala, BS; Kivlighn, SD | 1 |
| Laguzzi, R; Shvaloff, A | 1 |
| Coghlan, JP; Denton, DA; Nelson, M; Scoggins, BA; Tresham, JJ; Whitworth, JA | 1 |
| Furukawa, H; Ishikawa, K; Kameyama, T; Nabeshima, T; Yamaguchi, K | 1 |
| Smits, J; Struyker Boudier, H; van Dorsten, F | 1 |
| Geyer, MA; Tapson, GS | 1 |
| Björklund, M; Jäkälä, P; Kaukua, J; Koivisto, E; Riekkinen, P; Sirviö, J | 1 |
| Hirayama, T; Kikuchi, K; Morita, K; Ogawa, Y; Onodera, S; Takeda, A; Takenaka, T; Tobise, K | 1 |
| Gerdes, C; Löscher, W; Richter, A | 1 |
| Kolpakov, VG; Kozintsev, I; Kulikov, AV; Maslova, GB; Popova, NK | 1 |
| Cools, AR; Ellenbroek, BA; Prinssen, EP | 1 |
| Hong, E; López-Muñoz, FJ; Terrón, JA; Villalón, CM | 1 |
| Bakshi, VP; Geyer, MA; Swerdlow, NR | 1 |
| Bennie, J; Carroll, S; Dow, RC; Fink, G; Williams, BC | 1 |
| Brelière, JC; Congy, C; Le Fur, G; Pointeau, P; Rinaldi-Carmona, M; Vidal, H | 1 |
| Hirschelmann, R; Krause, E; Pertsch, M | 1 |
| Bouaboula, M; Brelière, JC; Casellas, P; Congy, C; Le Fur, G; Oury-Donat, F; Rinaldi-Carmona, M; Shire, D; Simiand, J; Soubrié, P | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS; Murnion, B | 1 |
| Horisaka, K; Kimura, I; Sugimoto, Y; Takeuchi, N; Watanabe, Y; Yamada, J | 1 |
| Grignaschi, G; Mantelli, B; Samanin, R | 1 |
| Branchek, TA; Kucharewicz, SA; Schechter, LE; Weinshank, RL; Zgombick, JM | 1 |
| Morishima, Y; Shibano, T | 1 |
| Bergh, A; Collin, O; Damber, JE | 1 |
| Böing, C; Bühlen, M; Fink, K; Göthert, M | 1 |
| Colpaert, FC; Palmier, C; Pauwels, PJ; Wurch, T | 1 |
| Sandyk, R | 1 |
| Beaughard, M; Massingham, R; Michelin, MT; Piera, MJ; Winslow, E | 1 |
| Dahl, SG; Kristiansen, K | 1 |
| Cozzi, NV; Nichols, DE | 1 |
| Ebling, FJ; Hastings, MH; Maywood, ES; Selvage, D; Sumova, A | 1 |
| Gommeren, W; Gysemans, M; Janssen, PM; Leysen, JE; Mertens, JJ; Terriere, D | 1 |
| Bertolino, F; Fauré, P; John, GW; Valentin, JP; Vieu, S | 1 |
| Marwood, JF; Okoro, EO | 1 |
| Matsumoto, K; Mizowaki, M; Murakami, Y; Thongpraditchote, S; Watanabe, H | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Choi, DS; Launay, JM; Maroteaux, L; Messaddeq, N; Ward, SJ | 1 |
| Cenarruzabeitia, E; Del Rio, J; Lasheras, B; Ramírez, MJ | 1 |
| Assié, MB; Kleven, MS; Koek, W | 1 |
| Kirov, R; Kortenska, L; Moyanova, S | 1 |
| Adamkiewicz, M; Buczko, W; Malyszko, J; Mysliwiec, M; Pawlak, D; Takada, A | 1 |
| Kennaway, DJ; Moyer, RW | 1 |
| Kulkarni, SK; Ninan, I | 1 |
| Sugimoto, Y; Yamada, J; Yoshikawa, T | 1 |
| Colpaert, FC; Pauwels, PJ; Wurch, T | 1 |
| Cardwell, GP; Hicks, CA; O'Neill, MF; O'Neill, MJ; Parameswaran, T; Shaw, G | 1 |
| Bennie, JG; Carroll, SM; Dow, RC; Fink, G; McQueen, JK | 1 |
| Harvey, JA; Hood, H; Romano, AG; Welsh, SE | 1 |
| Bult, H; Geerts, IS; Herman, AG; Matthys, KE | 1 |
| Del Bel, EA; Guimarães, FS; Nucci-da-Silva, LP | 1 |
| Alekhina, TA; Barykina, NN; Kulikov, AV; Naumenko, KS; Popova, NK | 1 |
| Fiorica-Howells, E; Gershon, MD; Maroteaux, L | 1 |
| DiNardo, LA; Ehlen, JC; Glass, JD | 1 |
| Sugimoto, Y; Yamada, J | 2 |
| Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T | 1 |
| Gessa, GL; Marchese, G; Pani, L; Ruiu, S; Saba, PL | 1 |
| Naylor, RJ; Tuladhar, BR; Womack, MD | 1 |
| Belluardo, P; Boscaro, M; Fallo, F; Fava, GA; Franceschetto, A; Sonino, N | 1 |
| Basura, GJ; Walker, PD | 1 |
| Bayer, BM; Pellegrino, TC | 1 |
| Matsushima, K; Tozawa, Y | 1 |
| Arjona, AA; Lee, RK; Pooler, AM; Wurtman, RJ | 1 |
| English, KB; He, L; Tuckett, RP | 1 |
| Fu, YJ; Miao, CY; Shu, H; Su, DF; Wang, MW | 1 |
| Alexandropoulou, KN; Demonakou, MD; Hereti, RI; Kourentzi, KT; Manta, GA; Mykoniatis, MG; Panoutsopoulos, GI; Papadimas, GK; Skaltsas, SD; Tzirogiannis, KN | 1 |
| Both, FL; Ghisleni, G; Kazlauckas, V; Mioranzza, S; Pagnussat, N; Porciúncula, LO; Rocha, JB; Souza, DO | 1 |
| Atwood, WJ; Lane, TE; O'Hara, BA; Schaumburg, C | 1 |
| France, CP; Li, JX; Rice, KC | 1 |
| France, CP; Javors, MA; Koek, W; Li, JX; Rice, KC; Unzeitig, A | 1 |
| Nakamichi, K; Nukuzuma, C; Nukuzuma, S; Takegami, T | 1 |
| Bannister, K; Bee, LA; Dickenson, AH; Rahman, W | 1 |
| Aloyo, VJ; Dave, KD; Harvey, JA; Schindler, EA; Smolock, EM | 1 |
| Choi, HS; Jun, DW; Kim, DC; Kim, EK; Kwon, YI; Lee, HL; Lee, KN; Lee, OY; Yoon, BC | 1 |
| Anisimova, VA; Mal'tsev, DV; Spasov, AA; Yakovlev, DS | 1 |
| Campbell, ST; Franks, CE; Harris, TE; Hsu, KL; Purow, BW | 1 |
| Bova, S; Fusi, F; Saponara, S; Sgaragli, G; Spiga, O; Trezza, A | 1 |
| Makiguchi, A; Okada, T; Shioda, K; Suda, S | 1 |
3 review(s) available for ketanserin and ritanserin
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors.
Topics: Brain; Humans; Ligands; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Serotonin | 2022 |
Antihypertensive mode of action of ketanserin.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Carcinoid Heart Disease; Humans; Ketanserin; Piperidines; Prazosin; Ritanserin | 1987 |
6 trial(s) available for ketanserin and ritanserin
| Article | Year |
|---|---|
Does acute serotonergic type-2 antagonism reduce blood pressure? Comparative effects of single doses of ritanserin and ketanserin in essential hypertension.
Topics: Adult; Affect; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Middle Aged; Piperidines; Receptors, Serotonin; Ritanserin | 1987 |
Experience with ketanserin and ritanserin in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Ketanserin; Male; Middle Aged; Piperidines; Ritanserin | 1988 |
The alpha-adrenergic receptor blocking effect of ketanserin and the interaction between alpha-adrenergic and S2-serotonergic receptor blockade.
Topics: Adrenergic alpha-Antagonists; Blood Pressure; Droperidol; Female; Humans; Ketanserin; Male; Middle Aged; Phentolamine; Phenylephrine; Piperidines; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin | 1988 |
Comparative haemodynamic effects of ketanserin and ritanserin in the proximal and distal upper limb circulations of hypertensive patients.
Topics: Arm; Blood Pressure; Brachial Artery; Double-Blind Method; Hand; Humans; Hypertension; Ketanserin; Middle Aged; Piperidines; Regional Blood Flow; Rheology; Ritanserin; Serotonin Antagonists; Vascular Resistance | 1989 |
Chronic 5-HT2-receptor blockade by ritanserin does not reduce blood pressure in patients with essential hypertension.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Histamine H2 Antagonists; Humans; Hypertension; Ketanserin; Male; Middle Aged; Piperidines; Ritanserin; Time Factors | 1987 |
Effect of the serotonin antagonists ritanserin and ketanserin in Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Hormones; Humans; Hydrocortisone; Ketanserin; Long-Term Care; Male; Middle Aged; Nelson Syndrome; Ritanserin; Serotonin Antagonists | 2000 |
131 other study(ies) available for ketanserin and ritanserin
| Article | Year |
|---|---|
Syntheses and 5-HT2 antagonist activity of bicyclic 1,2,4-triazol-3(2H)-one and 1,3,5-triazine-2,4(3H)-dione derivatives.
Topics: Animals; Bridged Bicyclo Compounds; Male; Mice; Rats; Serotonin Antagonists; Structure-Activity Relationship; Triazines; Triazoles | 1992 |
Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-HT2-antagonistic activity.
Topics: Animals; Antihypertensive Agents; Antipsychotic Agents; Blood Pressure; Chemical Phenomena; Chemistry; Dopamine; Imidazoles; Ketanserin; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Serotonin Antagonists; Structure-Activity Relationship | 1988 |
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1986 |
Development of a receptor-interaction model for serotonin 5-HT2 receptor antagonists. Predicting selectivity with respect to dopamine D2 receptors.
Topics: Indans; Indoles; Models, Chemical; Molecular Conformation; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1994 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents | 1996 |
Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist.
Topics: Benzamides; Binding, Competitive; Gene Expression; HeLa Cells; Humans; Kinetics; Ligands; Pyridines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Tritium | 1997 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.
Topics: Adenylyl Cyclases; Animals; Benzopyrans; Cell Line; Cell Membrane; Cloning, Molecular; Dihydroergotamine; Humans; Ligands; Mice; Propylamines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Sumatriptan; Vasoconstrictor Agents | 1998 |
Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; COS Cells; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hydrolysis; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Folding; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tryptamines | 2000 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Male; Mice; Molecular Docking Simulation; Protein Binding; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2C; Thiourea | 2016 |
Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening.
Topics: Cell Death; Computer Simulation; Diacylglycerol Kinase; Drug Evaluation, Preclinical; Humans; Lymphoproliferative Disorders; Piperidines; Protein Kinase Inhibitors; Pyrimidinones; Quinazolinones; Ritanserin; Thiazoles | 2019 |
Serotonin (5-HT2) receptor mediated enhancement of cortical unit activity.
Topics: Animals; Cerebral Cortex; Cinanserin; Cyproheptadine; Iontophoresis; Ketanserin; Male; Microelectrodes; Neurons; Pain; Physical Stimulation; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1992 |
Effects of the S2-serotonergic receptor antagonist, ketanserin, on cerulein-induced pancreatitis in the rat.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Dose-Response Relationship, Drug; Ketanserin; Male; Pancreatitis; Rats; Rats, Inbred Strains; Ritanserin; Serotonin | 1992 |
Effect of naftidrofuryl oxalate on 5-HT2 receptors in mouse brain: evaluation based on quantitative autoradiography and head-twitch response.
Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Behavior, Animal; Binding Sites; Brain Chemistry; Dose-Response Relationship, Drug; Ketanserin; Male; Methysergide; Mice; Nafronyl; Pargyline; Receptors, Serotonin; Ritanserin; Tissue Distribution | 1992 |
Fluoxetine and 8-OH-DPAT in the lateral septum enhances and impairs retention of an inhibitory avoidance response in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Brain Mapping; Dose-Response Relationship, Drug; Fear; Fluoxetine; Injections; Ketanserin; Male; Mental Recall; Rats; Rats, Inbred Strains; Receptors, Serotonin; Retention, Psychology; Ritanserin; Septum Pellucidum; Tetrahydronaphthalenes; Zimeldine | 1992 |
The selective 5-HT2 receptor antagonist amperozide attenuates 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane-induced inhibition of male rat sexual behavior.
Topics: Alprenolol; Amphetamines; Animals; Ergolines; Ketanserin; Male; Piperazines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Sexual Behavior, Animal | 1992 |
5HT2 receptor changes in rat cortex and platelets following chronic ritanserin and clorgyline administration.
Topics: Animals; Blood Platelets; Cerebral Cortex; Clorgyline; Homovanillic Acid; Hydroxyindoleacetic Acid; Ketanserin; Lysergic Acid Diethylamide; Male; Norepinephrine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin | 1990 |
DOI-induced inhibition of copulatory behavior in male rats: reversal by 5-HT2 antagonists.
Topics: Amphetamines; Animals; Copulation; Ejaculation; Female; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Tranquilizing Agents | 1991 |
Effects of serotonergic compounds on associative learning.
Topics: Animals; Atropine; Buspirone; Conditioning, Operant; Ketanserin; Learning; Male; Quinazolines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Serotonin Antagonists | 1991 |
Naloxone and serotonin receptor subtype antagonists: interactive effects upon deprivation-induced intake.
Topics: Animals; Drug Interactions; Feeding Behavior; Food Deprivation; Indoles; Ketanserin; Male; Methysergide; Naloxone; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Tropisetron | 1991 |
Effect of the 5-HT2 antagonist ketanserin on salt appetite in the rat.
Topics: Animals; Appetitive Behavior; Desoxycorticosterone; Female; Furosemide; Injections, Intraperitoneal; Injections, Intraventricular; Ketanserin; Male; Rats; Rats, Inbred Strains; Renin; Ritanserin; Sodium Chloride; Sucrose | 1991 |
Competitive antagonism by recognized 5-HT2 receptor antagonists at 5-HT1C receptors in pig choroid plexus.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Choroid Plexus; In Vitro Techniques; Inositol Phosphates; Ketanserin; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Swine | 1991 |
Effects of ketanserin tartrate on 3-hydroxy, 3-methylglutaryl coenzyme A reductase activity in cultured human skin fibroblasts.
Topics: Adrenergic alpha-Antagonists; Cells, Cultured; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Ketanserin; Piperidines; Prazosin; Ritanserin; Serotonin Antagonists | 1990 |
5-HT1C receptors in the serotonergic control of periaqueductal gray induced aversion in rats.
Topics: Amphetamines; Animals; Cyproheptadine; Indoles; Ketanserin; Male; Periaqueductal Gray; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement, Psychology; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
[3H]ketanserin binds to non-5-HT2 sites in rabbit cerebral cortex and neostriatum.
Topics: Animals; Binding, Competitive; Caudate Nucleus; Cell Membrane; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Ketanserin; Kinetics; Male; Methysergide; Mianserin; Piperidines; Putamen; Rabbits; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
Inhibition of spontaneous and evoked unit activity in the rat medial prefrontal cortex by mesencephalic raphe nuclei.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Ketanserin; Male; Membrane Potentials; Neurons; Piperidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Ritanserin; Serotonin | 1990 |
Inhibition of serotonin-amplified human platelet aggregation by ketanserin, ritanserin, and the ergoline 5HT2 receptor antagonists-LY53857, sergolexole, and LY237733.
Topics: Adult; Ergolines; Female; Humans; Ketanserin; Lysergic Acid; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
5HT-2 mediation of acute behavioral effects of hallucinogens in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Ketanserin; Male; Mescaline; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Tetrahydronaphthalenes | 1990 |
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
Effect of serotonergic drugs on negative contrast in consummatory behavior.
Topics: Animals; Buspirone; Chlordiazepoxide; Cyproheptadine; Dose-Response Relationship, Drug; Ethanol; Feeding Behavior; Fenclonine; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Midazolam; Nucleus Accumbens; Piperidines; Pyrimidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; In Vitro Techniques; Injections, Intravenous; Iontophoresis; Ketanserin; Male; Methysergide; Microelectrodes; Motor Neurons; Piperidines; Prazosin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes | 1990 |
Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Metergoline; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1990 |
Ketanserin and ritanserin can reduce reperfusion-induced but not ischaemia-induced arrhythmias in anaesthetised rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Female; Guinea Pigs; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists | 1987 |
Antihypertensive effects of ketanserin and ritanserin in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Ketanserin; Male; Phenylephrine; Piperidines; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin; Sympathetic Nervous System | 1988 |
5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Ergolines; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Piperidines; Pyrimidinones; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1988 |
Are drugs that act both on serotonin receptors and alpha 1-adrenoceptors more potent hypotensive agents than those that act only on alpha 1-adrenoceptors?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Cinanserin; Ergolines; Ketanserin; Male; Metergoline; Piperidines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1988 |
Arterial and venous effects of serotonin in the forearm of healthy subjects are not age-related.
Topics: Adult; Aged; Aging; Blood Pressure; Forearm; Heart Rate; Humans; Ketanserin; Male; Methoxamine; Middle Aged; Piperidines; Regional Blood Flow; Ritanserin; Serotonin; Serotonin Antagonists | 1989 |
Serotonin as a modulator of skeletal muscle oxygenation: effects of ketanserin and ritanserin on oxygen pressure distributions.
Topics: Animals; Ketanserin; Muscles; Oxygen; Oxygen Consumption; Piperidines; Pressure; Rabbits; Ritanserin; Serotonin; Serotonin Antagonists | 1989 |
Lack of a difference between ketanserin and ritanserin in central vs. peripheral serotonin receptor antagonism.
Topics: Animals; Blood Pressure; Corticosterone; Ketanserin; Male; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1989 |
Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Injections, Subcutaneous; Ketanserin; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes | 1989 |
5-Hydroxytryptamine stimulates the formation of inositol phosphate in astrocytes from different regions of the brain.
Topics: Animals; Astrocytes; Brain; Cyclic AMP; Inositol Phosphates; Ketanserin; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Stimulation, Chemical; Sugar Phosphates; Tissue Distribution | 1987 |
Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.
Topics: Animals; Binding, Competitive; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Female; Guinea Pigs; Haloperidol; Hippocampus; Histamine H2 Antagonists; In Vitro Techniques; Ketanserin; Kinetics; Male; Organ Specificity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1985 |
Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Decerebrate State; Histamine H2 Antagonists; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Theophylline; Vasoconstriction | 1986 |
Quipazine reduces food intake in the rat by activation of 5-HT2-receptors.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Eating; Histamine H2 Antagonists; Imidazoles; Ketanserin; Methysergide; Ondansetron; Pindolol; Piperidines; Quinolines; Quipazine; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1988 |
Chronic 5-HT2 receptor blockade with ritanserin does not reduce blood pressure in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hypertension; Ketanserin; Male; Phenylephrine; Piperidines; Prazosin; Rats; Rats, Inbred SHR; Receptors, Serotonin; Ritanserin; Time Factors | 1985 |
Antihypertensive mechanism of action of ketanserin and some ketanserin analogues in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Ketanserin; Phenylephrine; Piperidines; Prazosin; Pyrimidines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Ritanserin; Sympathetic Nervous System | 1985 |
Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone.
Topics: Animals; Brain; Corpus Striatum; Frontal Lobe; Ketanserin; Male; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Ritanserin | 1986 |
Evidence for separate receptors that mediate parallel effects of serotonin and small cardioactive peptideB (SCPB) on adenylate cyclase in Aplysia californica.
Topics: Adenylyl Cyclases; Animals; Aplysia; Enzyme Activation; Ketanserin; Neuropeptides; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1986 |
Antagonism by methysergide of neurogenic vasoconstriction in the dog forelimb.
Topics: Animals; Dogs; Electric Stimulation; Forelimb; Ketanserin; Median Nerve; Methysergide; Phentolamine; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Vascular Resistance; Vasoconstriction; Vasodilation | 1987 |
Serotonin receptors in the rat nucleus tractus solitarii and cardiovascular regulation.
Topics: Animals; Blood Pressure; Body Temperature; Cardiovascular Physiological Phenomena; Heart Rate; Indoles; Ketanserin; Male; Medulla Oblongata; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1986 |
Ritanserin and serotonergic mechanisms in blood pressure and fluid regulation in sheep.
Topics: Animals; Blood Pressure; Cardiac Output; Heart Rate; Hypertension; Ketanserin; Phenylephrine; Piperidines; Ritanserin; Serotonin; Serotonin Antagonists; Sheep; Water-Electrolyte Balance | 1987 |
Protection with phencyclidine against inactivation of 5-HT2 receptors by sulfhydryl-modifying reagents.
Topics: Animals; Behavior, Animal; Ethylmaleimide; Ketanserin; Male; Phencyclidine; Piperidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Ritanserin; Serotonin; Sulfhydryl Reagents | 1988 |
Interference of ketanserin with baroreflex control of the circulation in the conscious spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Ketanserin; Male; Piperidines; Prazosin; Pressoreceptors; Rats; Rats, Inbred SHR; Ritanserin; Serotonin Antagonists | 1988 |
Habituation of tactile startle is altered by drugs acting on serotonin-2 receptors.
Topics: Animals; Cinanserin; Cyproheptadine; Habituation, Psychophysiologic; Ketanserin; Male; Piperidines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Reflex, Startle; Ritanserin; Serotonin; Serotonin Antagonists; Touch | 1988 |
Modulation of rat neocortical high-voltage spindle activity by 5-HT1/5-HT2 receptor subtype specific drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Cerebral Cortex; Electroencephalography; Infusions, Parenteral; Ketanserin; Male; Methiothepin; Methysergide; Neural Pathways; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Thalamus | 1995 |
Comparison of 5-hydroxytryptamine-induced contraction of rat pulmonary artery to that of aorta in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Ketanserin; Male; Pindolol; Pulmonary Artery; Quinazolines; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Ritanserin; Serotonin; Vasoconstriction | 1995 |
Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia.
Topics: Animals; Blood Pressure; Body Temperature; Dantrolene; Female; Halothane; Heart Rate; Ketanserin; Male; Malignant Hyperthermia; Premedication; Ritanserin; Species Specificity; Swine | 1994 |
Effect of selective 5-HT1A agonists and 5-HT2 antagonists on inherited catalepsy in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Catalepsy; Dose-Response Relationship, Drug; Ketanserin; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
The role of serotonin receptor subtypes in the behavioural effects of neuroleptic drugs. A paw test study in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Inhibition of serotonin-induced increase in canine external carotid blood flow by drugs that decrease the sympathetic outflow.
Topics: Animals; Blood Pressure; Carotid Arteries; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Infusions, Intra-Arterial; Injections, Intravenous; Ketanserin; Male; Mecamylamine; Methiothepin; Prazosin; Receptors, Serotonin; Regional Blood Flow; Regression Analysis; Ritanserin; Serotonin; Spiro Compounds; Vascular Resistance | 1994 |
Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.
Topics: Acoustic Stimulation; Animals; Benzazepines; Clozapine; Dizocilpine Maleate; Ketanserin; Male; Phencyclidine; Raclopride; Rats; Rats, Sprague-Dawley; Reflex, Startle; Ritanserin; Salicylamides | 1994 |
A central 5-HT2 receptor mechanism plays a key role in the proestrous surge of luteinizing hormone in the rat.
Topics: Animals; Female; Ketanserin; Luteinizing Hormone; Prazosin; Proestrus; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin | 1994 |
Identification of binding sites for SR 46349B, a 5-hydroxytryptamine2 receptor antagonist, in rodent brain.
Topics: Animals; Binding, Competitive; Brain; Fluorobenzenes; In Vitro Techniques; Ketanserin; Male; Mice; Phenols; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1994 |
A comparison of serotonin (5-HT) blood levels and activity of 5-HT2 antagonists in adjuvant arthritic Lewis and Wistar rats.
Topics: Animals; Arthritis, Experimental; Disease Susceptibility; Female; Ketanserin; Rats; Rats, Inbred Lew; Rats, Wistar; Ritanserin; Serotonin; Species Specificity | 1993 |
Up-regulation of 5-HT2 receptors in the rat brain by repeated administration of SR 46349B, a selective 5-HT2 receptor antagonist.
Topics: Amphetamines; Animals; Base Sequence; Blotting, Southern; Brain Chemistry; Cerebral Cortex; Fluorobenzenes; In Vitro Techniques; Inosine Monophosphate; Ketanserin; Male; Molecular Sequence Data; Phenols; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; RNA, Messenger; Second Messenger Systems; Serotonin Antagonists; Serotonin Receptor Agonists; Up-Regulation | 1993 |
Excitation and inhibition of rat medial vestibular nucleus neurones by 5-hydroxytryptamine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Immunohistochemistry; Ketanserin; Male; Neurons; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Vestibular Nuclei | 1993 |
Peripherally administered serotonin induces hyperglucagonemia in mice.
Topics: Animals; Glucagon; Indoles; Injections, Intraperitoneal; Ketanserin; Male; Methysergide; Mice; Mice, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Tropisetron | 1993 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Models, Animal; Feeding Behavior; Ketanserin; Male; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Ritanserin; Stress, Physiological | 1993 |
Ketanserin and ritanserin discriminate between recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes.
Topics: Binding, Competitive; Humans; Ketanserin; Methiothepin; Radioligand Assay; Receptors, Serotonin; Recombinant Proteins; Ritanserin; Second Messenger Systems; Serotonin Antagonists | 1995 |
Evidence that 5-HT2A receptors are not involved in 5-HT-mediated thermoregulation in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Drug; Ketanserin; Male; Mice; Mice, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin | 1995 |
5-Hydroxytryptamine--a local regulator of testicular blood flow and vasomotion in rats.
Topics: Administration, Topical; Animals; Dose-Response Relationship, Drug; Histamine; Injections; Ketanserin; Laser-Doppler Flowmetry; Male; Microcirculation; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Testis | 1996 |
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines | 1996 |
Pharmacology of cloned human 5-HT1D receptor-mediated functional responses in stably transfected rat C6-glial cell lines: further evidence differentiating human 5-HT1D and 5-HT1B receptors.
Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Humans; Ketanserin; Neuroglia; Rats; Receptors, Serotonin; Ritanserin; RNA, Messenger | 1996 |
Bidirectional effect of electromagnetic fields on ketanserin-induced yawning in patients with multiple sclerosis: the role of melatonin.
Topics: Adult; Electromagnetic Fields; Female; Humans; Ketanserin; Male; Melatonin; Middle Aged; Multiple Sclerosis; Ritanserin; Serotonin Antagonists; Yawning | 1996 |
Lack of efficacy of 5-HT2A receptor antagonists to reduce brain damage after 3 minutes of transient global cerebral ischaemia in gerbils.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Gerbillinae; Ischemic Attack, Transient; Ketanserin; Male; Motor Activity; Nerve Degeneration; Ritanserin; Serotonin Antagonists | 1995 |
Molecular modeling of serotonin, ketanserin, ritanserin and their 5-HT2C receptor interactions.
Topics: Animals; Ketanserin; Models, Chemical; Models, Molecular; Molecular Conformation; Rats; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1996 |
5-HT2A receptor antagonists inhibit potassium-stimulated gamma-aminobutyric acid release in rat frontal cortex.
Topics: Animals; Dose-Response Relationship, Drug; Frontal Lobe; gamma-Aminobutyric Acid; Ketanserin; Male; Potassium; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin Antagonists | 1996 |
Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster.
Topics: Animals; Arousal; Circadian Rhythm; Cricetinae; Ketanserin; Light; Male; Mesocricetus; Ritanserin; Serotonin Antagonists | 1996 |
Evaluation of radioiodo-4-amino-N-[1-[3-(4-fluorophenoxy)-propyl]-4- methyl-4-piperidinyl]-5-iodo-2-methoxybenzamide as a potential 5HT2 receptor tracer for SPE(C)T.
Topics: Animals; Binding, Competitive; Brain; In Vitro Techniques; Isotope Labeling; Ketanserin; Male; Membranes; Radioactive Tracers; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Agents; Serotonin Antagonists; Tomography, Emission-Computed, Single-Photon | 1995 |
Differential involvement of serotonin 2A/C and thromboxane A2/prostanoid receptors in high- vs. low-shear rate arterial thrombosis in rabbits.
Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Carotid Stenosis; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart Rate; Hemodynamics; Hydrazines; Jugular Veins; Ketanserin; Male; Oxadiazoles; Piperazines; Platelet Aggregation; Prazosin; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Prostaglandin; Receptors, Serotonin; Receptors, Thromboxane; Ritanserin; Serotonin Antagonists; Stress, Mechanical | 1997 |
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil | 1997 |
alpha2-Adrenoceptor antagonists reverse the 5-HT2 receptor antagonist suppression of head-twitch behavior in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Drug Evaluation, Preclinical; Fenclonine; Head Movements; Ketanserin; Male; Mice; Mice, Inbred Strains; Norepinephrine; Oxidopamine; Ritanserin; Serotonin; Serotonin Antagonists | 1997 |
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1997 |
5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.
Topics: Animals; Binding Sites; Brain; Cell Differentiation; DNA Primers; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Induction; Gene Expression Regulation, Developmental; Heart; Humans; In Situ Hybridization; Ketanserin; Methysergide; Mice; Microscopy, Electron, Scanning; Morphogenesis; Neural Crest; Organ Culture Techniques; Paroxetine; Polymerase Chain Reaction; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Ritanserin; RNA, Messenger; Serotonin; Serotonin Antagonists; Signal Transduction; Transcription, Genetic | 1997 |
5-HT2 receptor regulation of acetylcholine release induced by dopaminergic stimulation in rat striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzazepines; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Male; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Potassium; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Substance P | 1997 |
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzopyrans; Discrimination, Psychological; Ketanserin; Lysergic Acid Diethylamide; Male; Nicotinic Acids; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
High-voltage electroencephalogram spindles in rats, aging and 5-HT2 antagonism.
Topics: Aging; Alpha Rhythm; Animals; Cyproheptadine; Electroencephalography; Ketanserin; Male; Rats; Rats, Wistar; Ritanserin; Serotonin Antagonists; Time Factors | 1998 |
Vascular and cardiac effects of DV-7028, a selective, 5-HT2-receptor antagonist in rats.
Topics: Animals; Baroreflex; Blood Pressure; Cardiovascular System; Coronary Circulation; Heart; Heart Rate; Hindlimb; Injections, Intravenous; Ketanserin; Male; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Triazines; Vagotomy | 1998 |
Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms.
Topics: Amphetamines; Animals; Body Temperature; Circadian Rhythm; Ketanserin; Light; Male; Melatonin; Periodicity; Photic Stimulation; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 1998 |
5-HT2A receptor antagonists block MK-801-induced stereotypy and hyperlocomotion.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Ketanserin; Locomotion; Male; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereotypic Movement Disorder | 1998 |
p-Chloroamphetamine, a serotonin-releasing drug, elicited in rats a hyperglycemia mediated by the 5-HT1A and 5-HT2B/2C receptors.
Topics: 4-Aminobenzoic Acid; Adrenal Medulla; Adrenalectomy; Aminopyridines; Animals; Blood Glucose; Dose-Response Relationship, Drug; Ergolines; Fenclonine; Hyperglycemia; Indoles; Ketanserin; Male; Methysergide; p-Chloroamphetamine; para-Aminobenzoates; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin; Serotonin Agents; Serotonin Antagonists; Tropisetron | 1998 |
Chimeric receptor analysis of the ketanserin binding site in the human 5-Hydroxytryptamine1D receptor: importance of the second extracellular loop and fifth transmembrane domain in antagonist binding.
Topics: Amino Acid Sequence; Animals; Binding Sites; COS Cells; Dogs; Guinea Pigs; Humans; Ketanserin; Molecular Sequence Data; Point Mutation; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1998 |
Effects of 5-hydroxytryptamine2 receptor antagonism on the behavioral activation and immediate early gene expression induced by dizocilpine.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Haloperidol; HSP70 Heat-Shock Proteins; Immediate-Early Proteins; Immunohistochemistry; Ketanserin; Mice; Motor Activity; Proto-Oncogene Proteins c-fos; Ritanserin; Serotonin Antagonists | 1998 |
Serotonergic 5-HT2A receptors important for the oestradiol-induced surge of luteinising hormone-releasing hormone in the rat.
Topics: Anesthesia; Anesthetics; Animals; Cyclic S-Oxides; Diestrus; Estradiol; Female; Fluoxetine; Gonadotropin-Releasing Hormone; Ketanserin; Naphthalenes; Ovariectomy; Pituitary Gland; Pregnanediones; Proestrus; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 1999 |
Effect of 5-HT2 receptor antagonists on a cranial nerve reflex in the rabbit: evidence for inverse agonism.
Topics: Animals; Cranial Nerves; Ergolines; Female; Ketanserin; Lysergic Acid Diethylamide; Male; Mianserin; Piperidines; Rabbits; Receptors, Serotonin; Reflex; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction | 1999 |
Serotonin modulation of catalepsy induced by N(G)-nitro-L-arginine in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds, Heterocyclic; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indoles; Ketanserin; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Prazosin; Ritanserin; Serotonin Antagonists; Time Factors | 1999 |
[Effect of 5HT2 receptor blockade on the startle reflex and its prepulse inhibition in mice and rats of various strains].
Topics: Animals; Catalepsy; Cyproheptadine; Ketanserin; Mice; Mice, Inbred CBA; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reflex, Startle; Ritanserin; Serotonin Antagonists; Species Specificity | 1999 |
Serotonin and the 5-HT(2B) receptor in the development of enteric neurons.
Topics: Age Factors; Amphetamines; Animals; Antibodies; Antigens, Differentiation; Cell Differentiation; Cells, Cultured; Female; Fetus; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Guinea Pigs; In Situ Hybridization; Indoles; Intestines; Ketanserin; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myenteric Plexus; Neurons; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Ritanserin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Ubiquitin Thiolesterase | 2000 |
Dorsal raphe nuclear stimulation of SCN serotonin release and circadian phase-resetting.
Topics: Animals; Cinanserin; Circadian Rhythm; Cricetinae; Electric Stimulation; Ketanserin; Male; Mesocricetus; Neural Pathways; Piperazines; Raphe Nuclei; Ritanserin; Serotonin; Serotonin Antagonists; Suprachiasmatic Nucleus | 2000 |
The 5-HT(2C/2B) receptor agonist, m-chlorophenylpiperazine, increases plasma glucagon levels in rats.
Topics: Adrenal Medulla; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Ketanserin; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |
The serotonin 5-HT(2A) receptor subtype does not mediate apomorphine-induced aggressive behaviour in male Wistar rats.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Time Factors | 2000 |
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium | 2000 |
Pharmacological characterization of the 5-HT receptor-mediated contraction in the mouse isolated ileum.
Topics: Animals; Atropine; Dioxanes; Dose-Response Relationship, Drug; Female; Granisetron; Ileum; In Vitro Techniques; Indoles; Ketanserin; Male; Mice; Muscle Contraction; Ondansetron; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropanes; Tropisetron | 2000 |
Effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on plasma glucose and glucagon levels of rats.
Topics: Adrenal Medulla; Amphetamines; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Hyperglycemia; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Serotonin 2A receptor regulation of striatal neuropeptide gene expression is selective for tachykinin, but not enkephalin neurons following dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sympatholytics; Tachykinins; Transcription, Genetic | 2001 |
Role of central 5-HT(2) receptors in fluoxetine-induced decreases in T lymphocyte activity.
Topics: Animals; Fluoxetine; Immunosuppression Therapy; Injections; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; T-Lymphocytes | 2002 |
Peripheral 5-HT(2A)-receptor-mediated formation of an inhibitor of atrial natriuretic peptide binding involves inflammation.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atrial Natriuretic Factor; Catecholamines; Cyclooxygenase Inhibitors; Dexamethasone; Ditiocarb; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Indomethacin; Inflammation; Isatin; Ketanserin; Muscle, Smooth; Prazosin; Propranolol; Protein Binding; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Serotonin, 5-HT2A; Receptors, Angiotensin; Receptors, Serotonin; Reserpine; Ritanserin; Serotonin; Serotonin Receptor Agonists; Tyrosine 3-Monooxygenase; Urination; Vascular Resistance; Yohimbine | 2002 |
Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Body Weight; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Hippocampus; Ketanserin; Male; Norfenfluramine; Peptide Fragments; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin | 2002 |
5-HT2 and 3 receptor antagonists suppress the response of rat type I slowly adapting mechanoreceptor: an in vitro study.
Topics: Action Potentials; Adaptation, Physiological; Animals; Female; Free Radical Scavengers; Ketanserin; Male; Mechanoreceptors; Organ Culture Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Serotonin Antagonists; Skin; Tropanes | 2003 |
Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Female; Ketanserin; Male; Myocardial Infarction; Prazosin; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Ritanserin; Time Factors | 2004 |
Effect of 5-HT(2) receptor blockade on cadmium-induced acute toxicity.
Topics: Animals; Apoptosis; Cadmium; Disease Models, Animal; In Situ Nick-End Labeling; Ketanserin; Liver Failure, Acute; Male; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Treatment Outcome | 2007 |
Diphenyl diselenide exerts anxiolytic-like effect in Wistar rats: putative roles of GABAA and 5HT receptors.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Benzene Derivatives; Bicuculline; Defecation; Electroshock; Exploratory Behavior; GABA Antagonists; Ketanserin; Male; Organoselenium Compounds; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, GABA-A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 2008 |
Human embryonic stem cell-derived oligodendrocyte progenitor cells express the serotonin receptor and are susceptible to JC virus infection.
Topics: Antibodies, Monoclonal; Antigens; Biomarkers; Cell Line; Embryonic Stem Cells; Fetus; Humans; JC Virus; Ketanserin; Leukoencephalopathy, Progressive Multifocal; Oligodendroglia; Proteoglycans; Receptor, Serotonin, 5-HT2A; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2008 |
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys: antagonism and apparent pA2 analyses.
Topics: Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Electroshock; Fluorobenzenes; Hallucinogens; Ketanserin; Macaca mulatta; Phenethylamines; Piperidines; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Regression Analysis; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Animals; Conditioning, Operant; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Ketamine; Ketanserin; Male; Morphine; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Inhibitory effect of serotonin antagonists on JC virus propagation in a carrier culture of human neuroblastoma cells.
Topics: Cell Line, Tumor; Down-Regulation; Humans; JC Virus; Ketanserin; Neuroblastoma; Receptor, Serotonin, 5-HT2A; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Virus Cultivation; Virus Replication | 2009 |
A pronociceptive role for the 5-HT2 receptor on spinal nociceptive transmission: an in vivo electrophysiological study in the rat.
Topics: Action Potentials; Amphetamines; Animals; Evoked Potentials; Ketanserin; Male; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission | 2011 |
Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).
Topics: Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dopamine; Frontal Lobe; Hallucinogens; Ketanserin; Lysergic Acid Diethylamide; Male; Rabbits; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Ritanserin; Serotonin; Serotonin Agents; Serotonin Antagonists; Temperature | 2012 |
5-HT2A receptor antagonists inhibit hepatic stellate cell activation and facilitate apoptosis.
Topics: Actins; Animals; Apoptosis; Cell Line; Cell Survival; Collagen Type I; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Humans; Ketanserin; Liver Cirrhosis, Experimental; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Serotonin, 5-HT2A; Ritanserin; RNA, Messenger; Serotonin 5-HT2 Receptor Antagonists; Smad2 Protein; Smad3 Protein; Succinates; Thioacetamide; Time Factors; Transforming Growth Factor beta; Wound Healing | 2013 |
Effect of 5-HT(2A) receptor antagonists on blood flow in the carotid vessels upon elevation of serotonin level.
Topics: Animals; Animals, Outbred Strains; Carotid Arteries; Drug Evaluation, Preclinical; Ketanserin; Male; Rats; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Vasoconstriction | 2014 |
The Ligand Binding Landscape of Diacylglycerol Kinases.
Topics: Adenosine Triphosphate; Binding Sites; Chromatography, High Pressure Liquid; Diacylglycerol Kinase; HEK293 Cells; Humans; Isotope Labeling; Ketanserin; Ligands; Peptides; Protein Binding; Protein Isoforms; Proteome; Recombinant Proteins; Ritanserin; Tandem Mass Spectrometry | 2017 |
Ritanserin blocks Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Binding Sites; Calcium Channels, L-Type; Electrophysiological Phenomena; Ketanserin; Male; Molecular Docking Simulation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Binding; Rats, Wistar; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Vasoconstriction | 2020 |
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists | 2020 |