ketanserin has been researched along with pyrilamine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (28.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A | 1 |
| Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Abdel-Hamid, MK; Andersson, S; Chau, N; Daniel, JA; Deane, FM; Hill, TA; McCluskey, A; Odell, LR; Robinson, PJ; Sakoff, JA; Young, KA | 1 |
| Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN | 1 |
| Feniuk, W; Humphrey, PP; Perren, MJ | 1 |
| Adelstein, RS; Corson, MA; Schoenberg, M; Sellers, JR | 1 |
| Gabel, RA; Macia, RA; Matthews, WD; Reginato, MJ | 1 |
| Braimbridge, MV; Erol, C; Hearse, DJ; Maxwell, MP; Saldanha, C; Sonmez, B | 1 |
| Acevedo, CG; Cruz, MA; Gonzalez, C; Rudolph, MI; Sepulveda, WH | 1 |
| Kawasaki, H; Takasaki, K | 1 |
| Bevan, J; Heptinstall, S | 2 |
| Laduron, PM; Leysen, JE; Van Dun, J; Wouters, W | 1 |
| Arakawa, H; Hayes, J; Kawikova, I; Löfdahl, CG; Lötvall, J; Morikawa, A; Skoogh, BE | 1 |
| Miller, DJ; O'Dowd, A | 1 |
| Hayashi, M; Ikawati, Z; Maeyama, K; Nose, M | 1 |
| Larrauri, JA; Levin, ED | 1 |
28 other study(ies) available for ketanserin and pyrilamine
| Article | Year |
|---|---|
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1986 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 2014 |
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming | 2015 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.
Topics: Binding, Competitive; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Drug Screening Assays, Antitumor; Dynamin I; Enzyme Inhibitors; Humans; Mass Spectrometry; Pleckstrin Homology Domains; Proton Magnetic Resonance Spectroscopy; Pyrimidines | 2017 |
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron | 1992 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents | 1991 |
Substance P contracts bovine tracheal smooth muscle via activation of myosin light chain kinase.
Topics: Animals; Atropine; Calcium; Cattle; Enzyme Activation; Glycopeptides; In Vitro Techniques; Indomethacin; Ketanserin; Kinetics; Masoprocol; Muscle Contraction; Muscle, Smooth; Myosin Subfragments; Myosin-Light-Chain Kinase; Peptide Mapping; Phosphorylation; Potassium Chloride; Prazosin; Propranolol; Pyrilamine; Substance P; Trachea | 1990 |
Hypotension induced by growth-hormone-releasing peptide is mediated by mast cell serotonin release in the rat.
Topics: Analysis of Variance; Animals; Cimetidine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Synergism; Growth Hormone-Releasing Hormone; Histamine H2 Antagonists; Histamine Release; Hormones; Hypotension; Injections, Intravenous; Ketanserin; Male; Mast Cells; Naloxone; Oligopeptides; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Particle-induced coronary vasoconstriction in the rat heart: pharmacological investigation of underlying mechanisms.
Topics: Animals; Bicarbonates; Calcium Chloride; Cimetidine; Coronary Circulation; Drug Contamination; Filtration; Heart Arrest, Induced; Isoproterenol; Ketanserin; Magnesium; Male; Methysergide; Phenylephrine; Potassium Chloride; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Sodium Chloride | 1986 |
Effects of histamine and serotonin on the contractility of isolated pregnant and nonpregnant human myometrium.
Topics: Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Humans; In Vitro Techniques; Ketanserin; Methysergide; Myometrium; Pregnancy; Pyrilamine; Serotonin; Uterine Contraction | 1989 |
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Serotonin-induced platelet aggregation in whole blood and the effects of ketanserin and mepyramine.
Topics: Aminopyridines; Dose-Response Relationship, Drug; Humans; Ketanserin; Piperidines; Platelet Aggregation; Pyrilamine; Serotonin; Time Factors | 1985 |
Differential photoaffinity labelling of serotonin-S2 receptors and histamine-H1 receptors using 7-azidoketanserin.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Butyrophenones; Cerebellum; Cerebral Cortex; Female; Guinea Pigs; Ketanserin; Photolysis; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Serotonin; Spiperone | 1985 |
Effects of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets.
Topics: Adenosine Diphosphate; Aminopyridines; Blood Platelets; Humans; Ketanserin; Piperidines; Platelet Aggregation; Pyrilamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1983 |
Role of arachidonic acid metabolites in airway responses induced by trimellitic anhydride in actively sensitized guinea pigs.
Topics: Airway Resistance; Animals; Arachidonic Acid; Bronchi; Evans Blue; Exudates and Transudates; Guinea Pigs; Immunization; Indazoles; Indomethacin; Ketanserin; Male; Methacrylates; Permeability; Phthalazines; Phthalic Anhydrides; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Thromboxane-A Synthase | 1993 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketanserin; Methiothepin; Muscle Contraction; Muscle Relaxation; Pyrilamine; Rabbits; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Saphenous Vein; Serotonin Antagonists; Vasoconstrictor Agents; Zinc | 1998 |
The lack of compound 48/80-induced contraction in isolated trachea of mast cell-deficient Ws/Ws rats in vitro: the role of connective tissue mast cells.
Topics: Animals; Anti-Asthmatic Agents; Carbachol; Connective Tissue; Female; Histamine; Histamine H1 Antagonists; Histocytochemistry; Ketanserin; Male; Mast Cells; Muscle, Smooth; Nedocromil; p-Methoxy-N-methylphenethylamine; Parasympathomimetics; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Trachea | 2000 |
PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin.
Topics: Acoustic Stimulation; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Female; Histamine H1 Antagonists; Inhibition, Psychological; Ketanserin; Physical Stimulation; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sensory Gating; Serotonin 5-HT2 Receptor Antagonists | 2010 |