ketanserin has been researched along with naloxone in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.18) | 18.7374 |
| 1990's | 10 (30.30) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dannals, RF; Frost, JJ; Ravert, HT; Wagner, HN; Wilson, AA | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Gabel, RA; Macia, RA; Matthews, WD; Reginato, MJ | 1 |
| Beczkowska, IW; Bodnar, RJ | 1 |
| Giordano, J | 1 |
| Kamei, J; Kasuya, Y; Tanihara, H | 1 |
| Bieger, D; Triggle, C | 1 |
| Aasen, AO; Pillgram-Larsen, J; Ruud, TE; Stadaas, JO | 2 |
| Emmers, R; Tamir, H; Wilchek, M | 1 |
| Beubler, E; Bukhave, K; Rask-Madsen, J | 1 |
| Goshadrou, F; Pourgholami, MH | 1 |
| Chen, DY; Koob, GF; Lau, C; Lin, T; Smith, NT; Weinger, MB | 1 |
| Aasen, AO; Naess, F; Roeise, O; Stadaas, JO; Waage, A | 1 |
| Ottani, A; Pini, LA; Sandrini, M; Vitale, G | 1 |
| Takeshita, N; Yamaguchi, I | 1 |
| Kulkarni, SK; Ninan, I | 1 |
| Castro-Souza, C; Coimbra, NC; Garcia-Cairasco, N; Herrero, CF; Nora, JE; Segato, EN; Tedeschi-Filho, W | 1 |
| Chu, YC; Pan, JT; Tsou, MY | 1 |
| Duman, EN; Erciyes, N; Kadioglu, M; Kalyoncu, NI; Kesim, M; Yaris, E | 1 |
| Coimbra, NC; Freitas, RL; Kishi, R; Morato, S; Rebouças, EC; Savoldi, M; Segato, EN | 1 |
| Kamei, J; Nozaki, C | 1 |
| Honda, M; Ono, H; Ono, K; Takasu, K; Tanabe, M; Tokuda, Y | 1 |
| Gupta, MC; Rani, S | 1 |
| Carrillo-Munguía, N; Díaz-Reval, MI; González-Trujano, ME; Huerta, M; Trujillo, X | 1 |
| Back, SK; Han, RT; Kim, HJ; Lee, H; Lee, J; Lee, SB; Na, HS | 1 |
1 review(s) available for ketanserin and naloxone
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
32 other study(ies) available for ketanserin and naloxone
| Article | Year |
|---|---|
Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist.
Topics: Animals; Dexetimide; Iodine Radioisotopes; Isotope Labeling; Male; Mice; Parasympatholytics; Piperidines; Receptors, Muscarinic; Tomography, Emission-Computed | 1989 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hypotension induced by growth-hormone-releasing peptide is mediated by mast cell serotonin release in the rat.
Topics: Analysis of Variance; Animals; Cimetidine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Synergism; Growth Hormone-Releasing Hormone; Histamine H2 Antagonists; Histamine Release; Hormones; Hypotension; Injections, Intravenous; Ketanserin; Male; Mast Cells; Naloxone; Oligopeptides; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Naloxone and serotonin receptor subtype antagonists: interactive effects upon deprivation-induced intake.
Topics: Animals; Drug Interactions; Feeding Behavior; Food Deprivation; Indoles; Ketanserin; Male; Methysergide; Naloxone; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Tropisetron | 1991 |
Analgesic profile of centrally administered 2-methylserotonin against acute pain in rats.
Topics: Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Ketanserin; Male; Mianserin; Motor Activity; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, Serotonin; Respiration; Serotonin; Serotonin Antagonists; Tropanes | 1991 |
Antitussive effects of two specific kappa-opioid agonists, U-50,488H and U-62,066E, in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antitussive Agents; Cisterna Magna; Cough; Injections; Ketanserin; Male; Methysergide; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Rats, Inbred Strains; Reflex | 1990 |
Pharmacological properties of mechanical responses of the rat oesophageal muscularis mucosae to vagal and field stimulation.
Topics: Animals; Dioxolanes; Electric Stimulation; Esophagus; Hexamethonium Compounds; In Vitro Techniques; Ketanserin; Male; Morphine; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Naloxone; Piperidines; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Serotonin; Tetrodotoxin; Tubocurarine; Vagus Nerve | 1985 |
Multitherapy: a new treatment regimen in endotoxemia.
Topics: Animals; Drug Therapy, Combination; Endotoxins; Escherichia coli; Hemodynamics; Kallikreins; Ketanserin; Methylprednisolone; Naloxone; Oxygen; Promethazine; Protease Inhibitors; Shock, Septic; Swine | 1987 |
Hemodynamic consequences of multitherapy pretreatment in experimental endotoxemia.
Topics: Animals; Drug Therapy, Combination; Endotoxins; Escherichia coli; Hemodynamics; Ketanserin; Lipopolysaccharides; Methylprednisolone; Naloxone; Oxygen; Promethazine; Protease Inhibitors; Pulmonary Circulation; Shock, Septic; Swine | 1987 |
Influence of a serotonin receptor antagonist, 5-HTP-DP-hex, on spinal and thalamic nociceptive neurons in rats.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Ketanserin; Male; Methysergide; Naloxone; Nerve Fibers; Pain; Periaqueductal Gray; Rats; Reaction Time; Sciatic Nerve; Spinothalamic Tracts; Thalamic Nuclei | 1987 |
Colonic secretion mediated by prostaglandin E2 and 5-hydroxytryptamine may contribute to diarrhea due to morphine withdrawal in the rat.
Topics: Animals; Atropine; Clonidine; Colon; Cyclic AMP; Diarrhea; Dinoprostone; Female; Humans; Indomethacin; Ketanserin; Morphine Dependence; Naloxone; Piperidines; Prostaglandins E; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome | 1984 |
Evidence for serotonergic system involvement in the effect of morphine on gastrointestinal motility in the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Central Nervous System; Charcoal; Depression, Chemical; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Gastrointestinal Motility; Ketanserin; Male; Morphine; Naloxone; Rats; Serotonin | 1995 |
A role for CNS alpha-2 adrenergic receptors in opiate-induced muscle rigidity in the rat.
Topics: Adrenergic alpha-Agonists; Alfentanil; Animals; Electromyography; Hindlimb; Imidazoles; Ketanserin; Male; Medetomidine; Muscle Rigidity; Naloxone; Narcotics; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1995 |
Effects of a combined drug regimen on tumour necrosis factor and plasma kallikrein activity in experimental endotoxaemia.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli Infections; Hemodynamics; Kallikreins; Ketanserin; Methylprednisolone; Naloxone; Promethazine; Protease Inhibitors; Shock, Septic; Swine; Tumor Necrosis Factor-alpha | 1994 |
Naloxone-reversible antinociception by paracetamol in the rat.
Topics: Acetaminophen; Animals; Cerebral Cortex; Formaldehyde; Hot Temperature; Ketanserin; Kinetics; Male; Morphine; Motor Activity; Naloxone; Pain; Pons; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Stereotyped Behavior | 1997 |
Insulin attenuates formalin-induced nociceptive response in mice through a mechanism that is deranged by diabetes mellitus.
Topics: Analgesics; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Indoles; Insulin; Ketanserin; Male; Mice; Mice, Inbred C57BL; Naloxone; Pindolol; Streptozocin; Sulpiride; Tropisetron | 1997 |
Ketanserin reverses dizocilpine-suppression of morphine dependence but not tolerance in mice.
Topics: Animals; Dizocilpine Maleate; Drug Combinations; Drug Tolerance; Excitatory Amino Acid Antagonists; Female; Ketanserin; Mice; Mice, Inbred BALB C; Morphine Dependence; Naloxone; Narcotic Antagonists | 2000 |
Post-ictal analgesia: involvement of opioid, serotoninergic and cholinergic mechanisms.
Topics: Analgesia; Animals; Atropine; Convulsants; Disease Models, Animal; Injections, Intraperitoneal; Ketanserin; Methysergide; Motor Activity; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Pain Measurement; Pentylenetetrazole; Rats; Rats, Wistar; Reaction Time; Reflex; Seizures; Serotonin Antagonists | 2001 |
Prostaglandins may participate in opioidergic and cholinergic control of the diurnal changes of tuberoinfundibular dopaminergic neuronal activity and serum prolactin level in ovariectomized, estrogen-treated rats.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Circadian Rhythm; Dopamine; Estrogens; Female; Hypothalamo-Hypophyseal System; Ketanserin; Median Eminence; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neurons; Opioid Peptides; Ovariectomy; Prolactin; Prostaglandins; Rats; Rats, Sprague-Dawley; Serotonin | 2001 |
The different roles of 5-HT(2) and 5-HT(3) receptors on antinociceptive effect of paroxetine in chemical stimuli in mice.
Topics: Abdominal Pain; Acetic Acid; Analgesia; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Injections, Intraperitoneal; Ketanserin; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Ondansetron; Pain Measurement; Paroxetine; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3 | 2005 |
Effect of the blockade of mu1-opioid and 5HT2A-serotonergic/alpha1-noradrenergic receptors on sweet-substance-induced analgesia.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesia; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Methysergide; Naloxone; Naltrexone; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Serotonin Antagonists; Sucrose; Taste | 2005 |
Possible involvement of opioidergic systems in the antinociceptive effect of the selective serotonin reuptake inhibitors in sciatic nerve-injured mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fluvoxamine; Hyperalgesia; Injections, Spinal; Ketanserin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Neuralgia; Ondansetron; Receptors, Opioid; Sciatic Nerve; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists; Time Factors | 2006 |
The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Biogenic Monoamines; Dose-Response Relationship, Drug; Fenclonine; Hot Temperature; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Ketanserin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Neural Pathways; Norepinephrine; Oxidopamine; Pain Measurement; Physical Stimulation; Reaction Time; Serotonin; Serotonin Agents; Sympatholytics; Thyrotropin; Thyrotropin-Releasing Hormone; Yohimbine | 2007 |
Evaluation and comparison of antinociceptive activity of aspartame with sucrose.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Aspartame; Disease Models, Animal; Ketanserin; Naloxone; Narcotic Antagonists; Pain; Rats; Rats, Wistar; Serotonin Antagonists; Sucrose | 2012 |
Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.
Topics: Analgesics, Opioid; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ketanserin; Naloxone; Ondansetron; Pain; Pain Measurement; Rats; Tramadol | 2015 |
Brief Isolation Changes Nociceptive Behaviors and Compromises Drug Tests in Mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Drug Evaluation, Preclinical; Feces; Hot Temperature; Ketanserin; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Narcotic Antagonists; Nociceptive Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Serotonin Antagonists; Social Isolation; Vasotocin | 2016 |