ketanserin has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 11 (39.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glennon, RA | 1 |
| Brodkin, J; Nash, JF | 1 |
| Gudelsky, GA; Meltzer, HY; Nash, JF | 1 |
| Arora, RC; Meltzer, HY; Nash, JF; Schreiber, MA | 1 |
| Azmitia, EC; Murphy, RB; Whitaker-Azmitia, PM | 1 |
| Appel, NM; De Souza, EB; Glennon, RA; Leonhardt, S; Teitler, M | 1 |
| Nash, JF | 1 |
| Barrett, JE; Hoffmann, SM; Nader, MA | 1 |
| Schmidt, CJ; Taylor, VL | 1 |
| Malberg, JE; Sabol, KE; Seiden, LS | 1 |
| Galloway, MP; Koch, S | 1 |
| Azmitia, EC; Kramer, HK; Poblete, JC | 1 |
| Gamma, A; Hell, D; Liechti, ME; Saur, MR; Vollenweider, FX | 1 |
| Geyer, MA; Hell, D; Liechti, ME; Vollenweider, FX | 1 |
| Fantegrossi, WE; Godlewski, T; Karabenick, RL; Rice, KC; Stephens, JM; Ullrich, T; Woods, JH | 1 |
| Arnold, JC; McGregor, IS; Morley, KC | 1 |
| Alvaro, AR; Ambrósio, AF; Carvalho, F; Cavadas, C; Costa, AC; Fernandes, E; Martins, J | 1 |
| Biezonski, DK; Courtemanche, AB; Hong, SB; Meyer, JS; Piper, BJ | 1 |
| Chaudhary, S; Fantegrossi, WE; Harding, WW; Legendre, O; Pecic, S; Zimmerman, SM | 1 |
| Abbas, AI; Beck, SG; Crawford, LK; Deneris, ES; Farrell, MS; Gingrich, J; Huang, XP; Irwin, JJ; Keiser, MJ; Kroeze, WK; Piel, DA; Roth, BL; Sciaky, N; Setola, V; Shoichet, BK; Yadav, PN | 1 |
| Christoffersen, M; Erritzoe, D; Frokjaer, VG; Holst, KK; Jernigan, TL; Johansen, SS; Knudsen, GM; Madsen, J; Ramsøy, T; Rasmussen, PM; Svarer, C | 1 |
| Anneken, JH; Gudelsky, GA | 1 |
| Hondebrink, L; Meulenbelt, J; Rietjens, SJ; Westerink, RH | 1 |
| Bexis, S; Docherty, JR | 1 |
| Daniju, Y; Davidson, C; Dawson, P; Dutta, N; Moffatt, JD; Opacka-Juffry, J; Ramsey, J | 1 |
| Antunes, MJ; Carvalho, F; Cotrim, MD; Fernandes, E; Silva, S | 1 |
| Aronsen, D; Bukholt, N; Foote, J; Highgate, Q; Schenk, S; Van de Wetering, R; Webster, J | 1 |
| de la Torre, R; Farre, M; Haijen, E; Kuypers, KPC; Olesti, E; Pastor, A; Pizarro, N; Ramaekers, JG | 1 |
1 review(s) available for ketanserin and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.
Topics: Animals; Blood Pressure; Body Temperature; Brain; Carbazoles; Carvedilol; Cytochrome P-450 CYP2D6; Drug Interactions; Glutathione Transferase; Haloperidol; Heart Rate; Humans; Ketanserin; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Transport Proteins; Polymorphism, Genetic; Propanolamines; Receptors, Neurotransmitter; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome | 2012 |
2 trial(s) available for ketanserin and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
Psychological and physiological effects of MDMA ("Ecstasy") after pretreatment with the 5-HT(2) antagonist ketanserin in healthy humans.
Topics: Adult; Affect; Analysis of Variance; Blood Pressure; Body Temperature; Double-Blind Method; Female; Hallucinations; Hallucinogens; Heart Rate; Humans; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Perception; Psychometrics; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Statistics, Nonparametric | 2000 |
Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication.
Topics: Adult; Arachidonic Acids; Double-Blind Method; Endocannabinoids; Female; Humans; Ketanserin; Male; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Polyunsaturated Alkamides; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Verbal Learning; Young Adult | 2018 |
25 other study(ies) available for ketanserin and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin | 2017 |
Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluoxetine; Ketanserin; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Effect of 3,4-methylenedioxymethamphetamine on 3,4-dihydroxyphenylalanine accumulation in the striatum and nucleus accumbens.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Serotonin; Serotonin Antagonists | 1990 |
Effect of 3,4-methylenedioxymethamphetamine on [3H]paroxetine binding in the frontal cortex and blood platelets of rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Blood Platelets; Frontal Lobe; Hydroxyindoleacetic Acid; Ketanserin; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Time Factors; Tritium | 1991 |
MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2(+)-dependent toxicity linked to release.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cells, Cultured; Embryo, Mammalian; Fluoxetine; Ketanserin; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Serotonin | 1990 |
Receptor pharmacology of MDMA and related hallucinogens.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Designer Drugs; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Ketanserin; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1990 |
Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1990 |
Behavioral effects of (+-) 3,4-methylenedioxyamphetamine (MDA) and (+-) 3,4-methylenedioxymethamphetamine (MDMA) in the pigeon: interactions with noradrenergic and serotonergic systems.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Metergoline; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Reinforcement Schedule; Serotonin; Sympathetic Nervous System | 1989 |
Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Ketanserin; Kinetics; Male; Methiothepin; N-Methyl-3,4-methylenedioxyamphetamine; Piperonyl Butoxide; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase | 1987 |
Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.
Topics: Animals; Body Temperature; Drug Combinations; Fluoxetine; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Tyrosine | 1996 |
MDMA induced dopamine release in vivo: role of endogenous serotonin.
Topics: Animals; Chromatography, High Pressure Liquid; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; In Vitro Techniques; Ketanserin; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists | 1997 |
Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter.
Topics: Animals; Binding Sites; Brain; Brain Stem; Carrier Proteins; Cerebral Cortex; Enzyme Activation; Female; Fluoxetine; Hippocampus; Ketanserin; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins | 1997 |
Effects of MDMA (ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin.
Topics: Acoustic Stimulation; Adult; Citalopram; Dose-Response Relationship, Drug; Double-Blind Method; Female; Habituation, Psychophysiologic; Haloperidol; Humans; Ketanserin; Male; Models, Psychological; N-Methyl-3,4-methylenedioxyamphetamine; Psychiatric Status Rating Scales; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin | 2001 |
Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice.
Topics: Animals; Body Temperature; Cold Temperature; Crowding; Dose-Response Relationship, Drug; Fluorobenzenes; Fluoxetine; Hallucinogens; Ketanserin; Lethal Dose 50; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Platelet Aggregation Inhibitors; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Isolation; Stereoisomerism; Telemetry | 2003 |
Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat.
Topics: Animals; Hallucinogens; Indoles; Interpersonal Relations; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Agents; Serotonin Antagonists; Serotonin Syndrome | 2005 |
Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy.
Topics: Animals; Cell Death; Cells, Cultured; Hot Temperature; Immunohistochemistry; Ketanserin; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuropeptide Y; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Retina; Serotonin Agents; Serotonin Antagonists | 2008 |
Repeated adolescent MDMA ("Ecstasy") exposure in rats increases behavioral and neuroendocrine responses to a 5-HT2A/2C agonist.
Topics: Amphetamines; Animals; Behavior, Animal; Brain; Corticosterone; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurosecretory Systems; Prolactin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents | 2009 |
Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aporphines; Appetite Depressants; Cyclization; Fluoroacetates; Iodobenzenes; Ketanserin; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Receptors, Adrenergic, alpha-1; Stereoisomerism; Trifluoroacetic Acid | 2010 |
The presynaptic component of the serotonergic system is required for clozapine's efficacy.
Topics: Acoustic Stimulation; Action Potentials; Adrenergic Uptake Inhibitors; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Checkpoint Kinase 2; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Ketanserin; Lysine; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Patch-Clamp Techniques; Phencyclidine; Presynaptic Terminals; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Radioligand Assay; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin; Serotonin Antagonists; Stereotyped Behavior; Tritium; Tryptophan Hydroxylase | 2011 |
In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users.
Topics: Adult; Amphetamine-Related Disorders; Aniline Compounds; Brain; Case-Control Studies; Cross-Sectional Studies; Female; Fluorine Radioisotopes; Hallucinogens; Humans; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Serotonin Plasma Membrane Transport Proteins; Sulfides | 2011 |
MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus.
Topics: Adrenergic Uptake Inhibitors; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Fluoxetine; Glutamic Acid; Hippocampus; Ketanserin; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Influence of ketanserin on the effects of methylenedioxymethamphetamine on body temperature in the mouse.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Aorta; Body Temperature; Fever; Ketanserin; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Prazosin; Rats; Serotonin Antagonists; Vas Deferens | 2013 |
The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat.
Topics: Animals; Aorta; Benzofurans; Brain; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; In Vitro Techniques; Iodine Isotopes; Ketanserin; Male; Muscle Contraction; N-Methyl-3,4-methylenedioxyamphetamine; Propylamines; Protein Binding; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Serotonin Agents; Tritium; Vasoconstriction | 2014 |
Contractile effects of 3,4-methylenedioxymethamphetamine on the human internal mammary artery.
Topics: Fluoxetine; Hallucinogens; Humans; In Vitro Techniques; Isometric Contraction; Ketanserin; Mammary Arteries; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2016 |
Serotonin antagonists fail to alter MDMA self-administration in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug-Seeking Behavior; Extinction, Psychological; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists | 2016 |