ketanserin has been researched along with metoprolol in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (61.54) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 5 (19.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Barankay, A; Heimisch, W; Hesse, S; Mendler, N; Schad, H | 2 |
| Fasano, ML; Ferrara, LA; Mancini, M; Marotta, G; Rubba, P; Soro, S | 1 |
| Bernardiner, E; Finkielman, S; Lemus, J; Milei, J; Nahmod, VE | 1 |
| Casiglia, E; Gava, R; Nicolin, P; Pessina, AC; Semplicini, A | 1 |
| Parag, KB; Seedat, YK | 1 |
| Gould, SE; Kane, JA; Sibbald, B; Tooley, M | 1 |
| Mauersberger, H | 1 |
| Bernardiner, E; Lemus, J; Milei, J | 2 |
| Assogna, G; Costantini, C; del Rosso, G; Libretti, A; Mara, G; Palermo, A; Pizza, N | 1 |
| Buzzaccarini, F; Casiglia, E; Dal Palù, C; Gava, R; Nicolin, P; Pessina, AC; Rossi, GP; Semplicini, A | 1 |
| Fasano, ML; Ferrara, LA; Iannuzzi, A; Rubba, P; Soro, S | 1 |
| Findlay, JG; Murray, GD | 1 |
| Buzzetti, G; Crispino, M; De Luca, N; Galletti, P; Rosiello, G; Trimarco, B; Volpe, M | 1 |
| Agerter, DC; Araas, FJ; Collins, JB; Fisher, LD; Schirger, A; Sheps, SG; Spiekerman, RE; Zachariah, PK | 1 |
| Finkielman, S | 1 |
| Deis, RP; Hole, D; Jahn, GA; Kalia, V; Wilson, CA | 1 |
1 review(s) available for ketanserin and metoprolol
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
14 trial(s) available for ketanserin and metoprolol
| Article | Year |
|---|---|
Study with the competitive 5-HT2-serotonergic antagonist ketanserin.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hypertension; Ketanserin; Leg; Metoprolol; Physical Exertion; Piperidines; Random Allocation; Regional Blood Flow; Serotonin Antagonists | 1985 |
Ketanserin in the treatment of essential hypertension. A double blind trial against metoprolol followed by one-year open treatment.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Statistics as Topic; Time Factors | 1989 |
The mechanism of the antihypertensive effects of ketanserin: a comparison with metoprolol.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Humans; Ketanserin; Metoprolol; Vascular Resistance | 1986 |
A comparative study of ketanserin and metoprolol in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Piperidines; Random Allocation; Time Factors | 1985 |
A comparative study of ketanserin and metoprolol in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Piperidines; Placebos | 1986 |
Long-term safety and efficacy of ketanserin in essential hypertension: ketanserin versus or in combination with metoprolol.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Piperidines; Random Allocation | 1986 |
Ketanserin versus metoprolol in the treatment of essential hypertension.
Topics: Adult; Aged; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Piperidines; Placebos | 1986 |
Clinical experience with ketanserin in the treatment of hypertension.
Topics: Double-Blind Method; Heart Rate; Humans; Hypertension; Ketanserin; Metoprolol; Piperidines | 1986 |
Cardiovascular effects of ketanserin, a new antiserotonergic agent in the treatment of arterial hypertension.
Topics: Adult; Blood Pressure; Body Weight; Exercise Test; Heart Rate; Hemodynamics; Humans; Hypertension; Ketanserin; Metoprolol; Middle Aged; Piperidines; Regional Blood Flow; Serotonin Antagonists; Vascular Resistance | 1985 |
Correcting for the bias caused by drop-outs in hypertension trials.
Topics: Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blind Method; Humans; Hypertension; Ketanserin; Metoprolol; Patient Dropouts; Random Allocation | 1988 |
Effects of chronic antihypertensive treatment with ketanserin versus metoprolol on blood pressure and large arteries' compliance in humans: a cross-over double-blind study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Brachial Artery; Cardiac Output; Compliance; Double-Blind Method; Female; Forearm; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Random Allocation; Regional Blood Flow; Ultrasonography; Vascular Resistance | 1988 |
Ketanserin in the treatment of essential hypertension. A double-blind study against metoprolol and a further long-term open treatment.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged | 1986 |
Comparison of ketanserin and metoprolol in the treatment of essential hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Posture; Time Factors | 1987 |
[Prolonged treatment with ketanserin in essential hypertension and comparison with metoprolol].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged | 1985 |
11 other study(ies) available for ketanserin and metoprolol
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Heart; Heart Rate; Ketanserin; Male; Metoprolol; Myocardial Contraction; Myocardial Ischemia; Premedication | 1992 |
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Heart; Heart Rate; Ketanserin; Metoprolol; Myocardial Contraction; Stroke Volume; Ventricular Function, Left | 1989 |
[Hypotensive effect of ketanserin and evaluation of its alpha-blocking activity].
Topics: Adult; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Metoprolol; Middle Aged; Random Allocation; Receptors, Adrenergic, alpha | 1986 |
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamines; Analysis of Variance; Animals; Brain Chemistry; Dopamine; Female; Fenclonine; Fenfluramine; Gestational Age; Ketanserin; Metoprolol; Norepinephrine; p-Chloroamphetamine; Prazosin; Pregnancy; Pregnancy, Animal; Prolactin; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1999 |