ketanserin and methyldopa

ketanserin has been researched along with methyldopa in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Lapidus, AM; Margulies, M; Neira, J; Voto, LS; Zin, C1
Alcocer, L; Copertari, P; Feruglio, F; Landi, E; Lopes, M; San Martin, C; Zin, C1
Janssens, M; Symoens, J1
Timmermans, PB; Van Brummelen, P; Van Zwieten, PA1
Bolte, AC; Dekker, GA; van Geijn, HP1
Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V1
Bhat, AD; Dombrowski, MM; Keasler, PM; Kolluru, L; Palanisamy, A; Singh, PM1

Reviews

4 review(s) available for ketanserin and methyldopa

ArticleYear
Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment.
    The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Calcium Channel Blockers; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; Ketanserin; Methyldopa; Muscle, Smooth, Vascular; Phenylacetates; Piperazines; Piperidines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Vascular Resistance

1984
Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 95, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Female; Humans; Hypertension; Ketanserin; Labetalol; Methyldopa; Nitric Oxide Donors; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Receptors, Serotonin; Serotonin Antagonists

2001
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:4

    Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease; Female; Fetal Growth Retardation; Furosemide; Gestational Age; Humans; Hypertension; Incidence; Infant, Small for Gestational Age; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Perinatal Death; Pindolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Severity of Illness Index

2020
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
    Pregnancy hypertension, 2023, Volume: 34

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as Topic

2023

Trials

3 trial(s) available for ketanserin and methyldopa

ArticleYear
Ketanserin versus alpha-methyldopa in the treatment of hypertension during pregnancy: a preliminary report.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 3

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Fetus; Humans; Ketanserin; Methyldopa; Pre-Eclampsia; Pregnancy; Random Allocation

1987
Evaluation of a new antihypertensive agent ketanserin versus methyldopa in the treatment of essential hypertension in older patients: an international multicenter trial.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 3

    Topics: Blood Pressure; Body Weight; Central Nervous System; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Methyldopa; Middle Aged; Random Allocation

1987
Ketanserin compared to nifedipine and methyldopa in patients aged above 50 years: two international multicentre studies. For the International Study Group.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:6

    Topics: Blood Pressure; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Methyldopa; Middle Aged; Nifedipine

1986

Other Studies

5 other study(ies) available for ketanserin and methyldopa

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010