ketanserin and ketanserinol

ketanserin has been researched along with ketanserinol in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's2 (11.76)18.2507
2000's4 (23.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barendregt, JN; Tjandra, YI; Van Der Hoeven, JG; Van Oene, JC; Van Peer, A1
Benhamou, JP; Berthelot, P; Fraitag, B; Gaudin, C; Hadengue, A; Lebrec, D; Levron, JC1
Gould, S; Gush, R; Jayson, MI; Kay, EA; Klimiuk, PS; Mitchell, WS; Taylor, L1
Kurowski, M1
Awouters, F; Heykants, J; Leysen, JE; Michiels, M; Schuurkes, J; Van Nueten, JM; Woestenborghs, R1
De Cree, J; Hendrickx, J; Heykants, J; Lauwers, W; Meuldermans, W; Van Peer, A; Woestenborghs, R1
Heykants, J; Knaeps, F; Meuldermans, W; Mostmans, E; Van Houdt, J; Verluyten, W1
Hedner, T; Persson, B; Pettersson, A1
Leeser, JE; Rawlins, MD; Williams, FM1
Embrechts, L; Heykants, J; Van Peer, A; Woestenborghs, R1
Gould, S; Heykants, J; Mills, J; Van Peer, A; Woestenborghs, R1
Frenken, M; Kaumann, AJ1
Lindelauf, F1
Schoenwald, RD; Zhu, J1
Hanff, LM; Vulto, AG; Yassen, A1
Sinclair-Worley, L; Uphouse, L1
Drozdov, I; Gustafsson, BI; Joseph, R; Kidd, M; Modlin, IM; Pfragner, R; Svejda, B1

Trials

3 trial(s) available for ketanserin and ketanserinol

ArticleYear
Pharmacokinetics of ketanserin in patients with cirrhosis.
    Clinical pharmacokinetics, 1990, Volume: 19, Issue:2

    Topics: Administration, Oral; Chromatography, High Pressure Liquid; Female; Humans; Injections, Intravenous; Ketanserin; Liver Cirrhosis; Male; Middle Aged; Models, Biological

1990
Pharmacodynamics and pharmacokinetics of single doses of ketanserin and propranolol alone and in combination in healthy volunteers.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:3

    Topics: Adult; Blood Pressure; Drug Administration Schedule; Female; Half-Life; Heart Rate; Humans; Ketanserin; Kinetics; Male; Middle Aged; Physical Exertion; Propranolol; Time Factors

1986
Pharmacokinetics of ketanserin and its metabolite ketanserin-ol in man after intravenous, intramuscular and oral administration.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:3

    Topics: Administration, Oral; Adult; Analysis of Variance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketanserin; Kinetics; Male; Random Allocation; Regression Analysis

1986

Other Studies

14 other study(ies) available for ketanserin and ketanserinol

ArticleYear
Ketanserin pharmacokinetics in patients with renal failure.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:6

    Topics: Adult; Aged; Blood Proteins; Female; Half-Life; Humans; Ketanserin; Kidney Failure, Chronic; Male; Middle Aged; Protein Binding; Renal Dialysis

1990
Ketanserin: an effective treatment regimen for digital ischaemia in systemic sclerosis.
    Scandinavian journal of rheumatology, 1989, Volume: 18, Issue:2

    Topics: Administration, Oral; Adult; Aged; Female; Fingers; Humans; Infusions, Intravenous; Ischemia; Ketanserin; Middle Aged; Pain Measurement; Scleroderma, Systemic

1989
Simultaneous determination of ketanserin and ketanserinol in biological fluids using ion-pair liquid chromatography and fluorometric detection.
    Journal of chromatography, 1985, May-31, Volume: 341, Issue:1

    Topics: Aged; Antihypertensive Agents; Body Fluids; Chromatography, High Pressure Liquid; Female; Humans; Hydrogen-Ion Concentration; Ketanserin; Kinetics; Piperidines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1985
Pharmacokinetic evaluation of the in vitro and in vivo pharmacological profile of the major metabolites of ketanserin in the rat.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cricetinae; In Vitro Techniques; Injections, Subcutaneous; Ketanserin; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Receptors, Drug; Stomach Ulcer

1988
Absorption, metabolism and excretion of ketanserin in man after oral administration.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Administration, Oral; Adult; Biotransformation; Chromatography, High Pressure Liquid; Feces; Humans; Ketanserin; Male

1988
Plasma protein binding of ketanserin and its distribution in blood.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:6

    Topics: Administration, Oral; Animals; Blood Proteins; Dogs; Drug Interactions; Humans; Hydrogen-Ion Concentration; Ketanserin; Male; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution

1988
Pharmacokinetics of ketanserin in patients with essential hypertension.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:3

    Topics: Administration, Oral; Aged; Biological Availability; Female; Half-Life; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Ketanserin; Kinetics; Male; Metabolic Clearance Rate; Middle Aged

1987
Pharmacokinetic approach to equilibrium between ketanserin and ketanserin-ol.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:3

    Topics: Administration, Oral; Adult; Half-Life; Humans; Ketanserin; Kinetics; Male; Oxidation-Reduction

1986
Interaction of ketanserin and its metabolite ketanserinol with 5HT2 receptors in pulmonary and coronary arteries of calf.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:4

    Topics: Animals; Cattle; Coronary Vessels; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Pulmonary Artery; Receptors, Serotonin; Yohimbine

1984
Determination of ketanserin and its major metabolite (reduced ketanserin) in human plasma by high-performance liquid chromatography.
    Journal of chromatography, 1983, Oct-14, Volume: 277

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Ketanserin; Oxidation-Reduction; Piperidines; Spectrophotometry, Ultraviolet

1983
The ocular pharmacokinetics of ketanserin and its metabolite, ketanserinol, in albino rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:5

    Topics: Administration, Topical; Animals; Eye; Female; Intraocular Pressure; Ketanserin; Male; Rabbits; Serotonin Antagonists

2000
Simultaneous quantitative analysis of ketanserin and ketanserinol in plasma by RP-HPLC with fluorescence detection.
    Biomedical chromatography : BMC, 2003, Volume: 17, Issue:8

    Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Ketanserin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

2003
Effect of estrogen on the lordosis-inhibiting action of ketanserin and SB 206553.
    Behavioural brain research, 2004, Jun-04, Volume: 152, Issue:1

    Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Female; Hypothalamus, Middle; Indoles; Ketanserin; Posture; Progesterone; Pyridines; Rats; Rats, Inbred F344; Serotonin Antagonists; Sexual Behavior, Animal; Time Factors

2004
Autoregulatory effects of serotonin on proliferation and signaling pathways in lung and small intestine neuroendocrine tumor cell lines.
    Cancer, 2009, Nov-01, Volume: 115, Issue:21

    Topics: Cell Line, Tumor; Cell Proliferation; Homeostasis; Humans; Intestinal Neoplasms; JNK Mitogen-Activated Protein Kinases; Ketanserin; Lung Neoplasms; Mitogen-Activated Protein Kinase 3; Neuroendocrine Tumors; Phosphorylation; Receptors, Serotonin; Serotonin; Signal Transduction; Tryptophan

2009