ketanserin and idazoxan

ketanserin has been researched along with idazoxan in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Alhaider, AA1
Petty, AC; Scrutton, MC1
Dusting, GJ; Li, DM1
Clarke, DE; Ford, AP; Lachnit, WG1
Aguerre, S; Chaouloff, F; Mormede, P1
Bourin, M; Dailly, E; Hascoët, M; Masse, F1
Anselmo-Franci, JA; Bícego, KC; de Souza Moreno, V; Gargaglioni, LH; Szawka, RE1
Dong, YL; Hu, W; Li, HS; Lu, GJ; Sun, YH; Wu, SX; Yang, J; Zhao, GL; Zhu, C1

Other Studies

13 other study(ies) available for ketanserin and idazoxan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antinociceptive effect of ketanserin in mice: involvement of supraspinal 5-HT2 receptors in nociceptive transmission.
    Brain research, 1991, Mar-15, Volume: 543, Issue:2

    Topics: Acetates; Acetic Acid; Adrenergic alpha-Antagonists; Analgesics; Animals; Brain Chemistry; Dioxanes; Dopamine; Idazoxan; Ketanserin; Male; Methysergide; Mice; Norepinephrine; Pain; Reaction Time; Receptors, Serotonin; Serotonin; Synaptic Transmission

1991
Platelet aggregation in whole blood: is the response to adrenaline, 5-hydroxytryptamine and PAF a direct consequence of stimulation by these agonists?
    Thrombosis research, 1989, Apr-15, Volume: 54, Issue:2

    Topics: Apyrase; Azepines; Cell Count; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Hirudins; Humans; Idazoxan; Indomethacin; Ketanserin; Platelet Activating Factor; Platelet Aggregation; Serotonin; Triazines; Triazoles

1989
Catecholamine release and potentiation of thromboxane A2 production by nicotine in the greyhound.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Catecholamines; Dioxanes; Dogs; Epinephrine; Female; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Ketanserin; Male; Nicotine; Phenoxybenzamine; Piperidines; Thromboxane A2; Vasoconstriction

1986
SDZ NVI 085, an alpha 1A-adrenoceptor agonist with 5-HT2A receptor antagonist properties.
    European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged-Ring Compounds; Idazoxan; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Regional Blood Flow; Serotonin Antagonists; Tail

1996
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
    Neuropharmacology, 1998, Volume: 37, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase

1998
Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:3

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzylamines; Brain; Cyclopropanes; Dopamine; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Fluorobenzenes; Idazoxan; Indoles; Ketanserin; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phenols; Prazosin; Punishment; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2005
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Hydroxyindoleacetic Acid; Hypercapnia; Idazoxan; Ketanserin; Locus Coeruleus; Male; Microinjections; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Respiration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2010
The analgesia effect of duloxetine on post-operative pain via intrathecal or intraperitoneal administration.
    Neuroscience letters, 2014, May-07, Volume: 568

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Idazoxan; Injections, Intraperitoneal; Injections, Spinal; Ketanserin; Male; Microdialysis; Norepinephrine; Pain, Postoperative; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spinal Cord; Thiophenes

2014