ketanserin has been researched along with desipramine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.86) | 18.7374 |
| 1990's | 14 (50.00) | 18.2507 |
| 2000's | 3 (10.71) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Barden, N; Peiffer, A; Veilleux, S | 1 |
| Drummer, D; Lerer, B; Newman, ME | 1 |
| Inoue, O; Kobayasi, K; Suhara, T | 1 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
| Cross, JA; Horton, RW | 1 |
| Göthert, M; Kollecker, P; Schlicker, E | 1 |
| Anwyl, R; Rowan, MJ | 1 |
| Baker, GB; McManus, DJ; Todd, KG | 1 |
| Friedman, E; Tilakaratne, N; Yang, Z | 1 |
| Little, KY; Mason, GA; Walker, CH | 1 |
| Elliott, P; Wallis, DI | 1 |
| Battaglia, G; Brownfield, MS; Cabrera, TM; Levy, AD; Li, Q; Rittenhouse, PA; van de Kar, LD | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J | 1 |
| Allikmets, L; Matto, V; Skrebuhhova, T | 1 |
| Cousins, MS; Overstreet, DH; Seiden, LS; Vosmer, G | 1 |
1 review(s) available for ketanserin and desipramine
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
27 other study(ies) available for ketanserin and desipramine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Antidepressant and other centrally acting drugs regulate glucocorticoid receptor messenger RNA levels in rat brain.
Topics: Amygdala; Animals; Antidepressive Agents; Blotting, Northern; Brain; Brain Chemistry; Desipramine; Female; Hippocampus; Hypothalamo-Hypophyseal System; Hypothalamus; Imipramine; Ketanserin; Lithium; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; RNA, Messenger; Sex Characteristics; Up-Regulation | 1991 |
Single and combined effects of desimipramine and lithium on serotonergic receptor number and second messenger function in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Desipramine; In Vitro Techniques; Inositol Phosphates; Ketanserin; Lithium; Male; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
Effect of desipramine on dopamine receptor binding in vivo.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzazepines; Cerebellum; Corpus Striatum; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Male; Mice; Receptors, Dopamine; Spiperone | 1990 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |
Effects of chronic oral administration of the antidepressants, desmethylimipramine and zimelidine on rat cortical GABAB binding sites: a comparison with 5-HT2 binding site changes.
Topics: Animals; Antidepressive Agents; Body Weight; Cerebral Cortex; Desipramine; Hippocampus; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Zimeldine | 1988 |
Receptor-mediated effects of serotonin and 5-methoxytryptamine on noradrenaline release in the rat vena cava and in the heart of the pithed rat.
Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Decerebrate State; Desipramine; Electric Stimulation; Heart; Heart Rate; Ketanserin; Male; Myocardium; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Tryptamines; Vagotomy; Vena Cava, Inferior | 1986 |
The effect of prolonged treatment with tricyclic antidepressants on the actions of 5-hydroxytryptamine in the hippocampal slice of the rat.
Topics: Animals; Cyproheptadine; Desipramine; Evoked Potentials; Hippocampus; Imipramine; In Vitro Techniques; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Clomipramine; Desipramine; Flunitrazepam; Fluoxetine; Ketanserin; Male; Maprotiline; Phenelzine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Chronic fluoxetine or desmethylimipramine treatment alters 5-HT2 receptor mediated c-fos gene expression.
Topics: Amphetamines; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Desipramine; Fluoxetine; Gene Expression; Genes, fos; Hippocampus; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Effects of concurrent subchronic treatments with desmethylimipramine and propranolol on beta-adrenergic and serotonin2 receptors in rat brain.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Desipramine; Dihydroalprenolol; Hippocampus; In Vitro Techniques; Ketanserin; Male; Membranes; Neostriatum; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin | 1993 |
Glutamatergic and non-glutamatergic responses evoked in neonatal rat lumbar motoneurons on stimulation of the lateroventral spinal cord surface.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Citalopram; Cocaine; Desipramine; Electric Stimulation; Ergolines; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Serotonin Antagonists; Spinal Cord; Strychnine; Synapses | 1993 |
Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI).
Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Desipramine; Drug Synergism; Fluoxetine; Hormones; Ketanserin; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Vasopressins | 1993 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1997 |
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium | 1999 |
[3H]-ketanserin binding and elevated plus-maze behavior after chronic antidepressant treatment in DSP-4 and P-CPA pretreated rats: evidence for partial involvement of 5-HT2A receptors.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzylamines; Binding Sites; Citalopram; Desipramine; Fenclonine; Ketanserin; Kinetics; Male; Maze Learning; Neurotransmitter Uptake Inhibitors; Protein Binding; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Tritium | 1999 |
Rats selectively bred for responsiveness to 5-hydroxytryptamine(1A) receptor stimulation: differences in differential reinforcement of low rate 72-second performance and response to serotonergic drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Age Factors; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hypothermia; Ketanserin; Male; Rats; Receptors, Serotonin; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |