ketanserin has been researched along with cimetidine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Abdel-Hamid, MK; Andersson, S; Chau, N; Daniel, JA; Deane, FM; Hill, TA; McCluskey, A; Odell, LR; Robinson, PJ; Sakoff, JA; Young, KA | 1 |
| Gabel, RA; Macia, RA; Matthews, WD; Reginato, MJ | 1 |
| Dikshit, M; Srimal, RC | 1 |
| Campbell, AM; Glatfelter, A; Kunkel, RG; Ulevitch, RJ; Wiggins, RC | 1 |
| Braimbridge, MV; Erol, C; Hearse, DJ; Maxwell, MP; Saldanha, C; Sonmez, B | 1 |
| Acevedo, CG; Cruz, MA; Gonzalez, C; Rudolph, MI; Sepulveda, WH | 1 |
| Kawasaki, H; Takasaki, K | 1 |
| Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL | 1 |
| Blocher, CR; Kellum, JM; Sielaff, TD; Sugerman, HJ; Tatum, JL | 1 |
| Miller, DJ; O'Dowd, A | 1 |
| SHUGAR, D; SZER, W | 1 |
| BLAUG, SM; RICH, AG | 1 |
| BANKER, GS; WOLFSON, BB | 1 |
27 other study(ies) available for ketanserin and cimetidine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.
Topics: Binding, Competitive; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Drug Screening Assays, Antitumor; Dynamin I; Enzyme Inhibitors; Humans; Mass Spectrometry; Pleckstrin Homology Domains; Proton Magnetic Resonance Spectroscopy; Pyrimidines | 2017 |
Hypotension induced by growth-hormone-releasing peptide is mediated by mast cell serotonin release in the rat.
Topics: Analysis of Variance; Animals; Cimetidine; Cyproheptadine; Dose-Response Relationship, Drug; Drug Synergism; Growth Hormone-Releasing Hormone; Histamine H2 Antagonists; Histamine Release; Hormones; Hypotension; Injections, Intravenous; Ketanserin; Male; Mast Cells; Naloxone; Oligopeptides; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Evidence for the presence of a new plasma factor which acts synergistically to ADP induced platelet aggregation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Animals; Biological Factors; Cimetidine; Drug Synergism; Enzymes; Epoprostenol; Heparin; Indomethacin; Ketanserin; Macaca mulatta; Male; Masoprocol; Mice; Mice, Inbred Strains; Phentolamine; Platelet Aggregation | 1990 |
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autonomic Nervous System; Blood Platelets; Bradycardia; Chemoreceptor Cells; Cimetidine; Complement C3; Dextran Sulfate; Dextrans; Factor XII; Histamine; Histamine Release; Hypotension; Injections, Intravenous; Ketanserin; Leukocyte Count; Lung; Male; Methysergide; Piperidines; Rabbits; Serotonin | 1985 |
Particle-induced coronary vasoconstriction in the rat heart: pharmacological investigation of underlying mechanisms.
Topics: Animals; Bicarbonates; Calcium Chloride; Cimetidine; Coronary Circulation; Drug Contamination; Filtration; Heart Arrest, Induced; Isoproterenol; Ketanserin; Magnesium; Male; Methysergide; Phenylephrine; Potassium Chloride; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Sodium Chloride | 1986 |
Effects of histamine and serotonin on the contractility of isolated pregnant and nonpregnant human myometrium.
Topics: Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Humans; In Vitro Techniques; Ketanserin; Methysergide; Myometrium; Pregnancy; Pyrilamine; Serotonin; Uterine Contraction | 1989 |
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin; Methylprednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Distress Syndrome; Swine | 1987 |
Treatment of porcine Pseudomonas ARDS with combination drug therapy.
Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug Combinations; Drug Therapy, Combination; Extracellular Space; Ibuprofen; Ketanserin; Lung; Methylprednisolone; Pseudomonas Infections; Respiratory Distress Syndrome; Serotonin; Swine | 1987 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketanserin; Methiothepin; Muscle Contraction; Muscle Relaxation; Pyrilamine; Rabbits; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Saphenous Vein; Serotonin Antagonists; Vasoconstrictor Agents; Zinc | 1998 |
Preparation of poly-5-fluorouridylic acid and the properties of halogenated poly-uridylic acids and their complexes with poly-adenylic acid.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Uracil Nucleotides; Uridine Monophosphate | 1963 |
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION.
Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines | 1965 |
SOLUBILIZATION AND EVALUATION OF POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE BARBITURATE SYSTEMS.
Topics: Barbiturates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Oxazoles; Oxazolidinones; Phenobarbital; Povidone; Research; Solubility | 1965 |