ketanserin has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 226 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (12.83) | 18.7374 |
| 1990's | 130 (57.52) | 18.2507 |
| 2000's | 45 (19.91) | 29.6817 |
| 2010's | 20 (8.85) | 24.3611 |
| 2020's | 2 (0.88) | 2.80 |
| Authors | Studies |
|---|---|
| Newman-Tancredi, A; Strange, PG; Wootton, R | 1 |
| Glennon, RA | 4 |
| Berardi, F; Colabufo, NA; Fiorentini, F; Ghiglieri, A; Govoni, S; Leopoldo, M; Olgiati, V; Perrone, R; Tortorella, V | 1 |
| Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S | 1 |
| Frescas, S; Gudelsky, GA; Huang, X; Marona-Lewicka, D; Nash, JF; Nichols, DE; Roth, BL | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Kung, HF; Kung, MP; Zhuang, ZP | 1 |
| Berardi, F; Colabufo, NA; Fiorentini, F; Govoni, S; Olgiati, V; Perrone, R; Tortorella, V; Vanotti, E | 1 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Berardi, F; Caccia, C; Fornaretto, MG; Leopoldo, M; McArthur, RA; Perrone, R; Tortorella, V | 1 |
| Berardi, F; Giudice, G; Govoni, S; Lucchi, L; Perrone, R; Tortorella, V | 1 |
| Berardi, F; Caccia, C; Colabufo, NA; Fornaretto, MG; Leopoldo, M; McArthur, RA; Perrone, R; Tortorella, V | 1 |
| Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R | 1 |
| Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP | 1 |
| Beleta, J; Doménech, T; Palacios, JM | 1 |
| Brown, AM; Collin, LL; Ellis, CE; Forbes, IT; Gittins, SA; Gloger, I; Hagan, J; Middlemiss, DN; Riley, G; Thomas, DR | 1 |
| Fujio, M; Katayama, J; Kuroita, T; Matsumoto, Y; Morio, Y; Togo, Y; Tomozane, H | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Berardi, F; Colabufo, NA; Contino, M; Lacivita, E; Leopoldo, M; Perrone, R | 1 |
| Betti, L; Caputo, F; Clerici, F; Fabbrini, L; Gelmi, ML; Giannaccini, G; Lucacchini, A; Palego, L; Pellegrino, S; Schmid, L | 1 |
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Caliendo, G; De Angelis, F; Esposito, A; Fiorino, F; Frecentese, F; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B; Viti, B | 1 |
| Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J | 1 |
| Caliendo, G; Ciano, A; Esposito, A; Fiorino, F; Frecentese, F; Incisivo, GM; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Benhamú, B; Berkels, R; Lauterbach, T; López-Rodríguez, ML; Marco, I; Martín-Fontecha, M; Ramos, JA; Valhondo, M; Vázquez-Villa, H | 1 |
| Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A | 1 |
| Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Lepailleur, A; Rochais, C; Thirumaran, SL | 1 |
| Chen, Z; Collier, T; Fu, H; Liang, SH; Rong, J; Zhou, J | 1 |
| Brands, J; Dijkema, R; Olijve, W; Stam, NJ; Tonnaer, JA; Van Alebeek, C; Van Huizen, F | 1 |
| Jacobs, M; McRee, C; Meyer, DC | 1 |
| Hasegawa, H; Nakamura, M; Wada, Y; Yamaguchi, N | 1 |
| Miletic, V; Tan, H | 1 |
| Griebel, G; Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Widmer, U | 1 |
| Aulakh, CS; Goldman, D; Hulihan-Giblin, BA; Park, YD | 1 |
| Clark, AH; Garland, CJ; Seager, JM | 1 |
| Chen, HY; Lee, EH; Liang, KC; Lin, WR; Shiu, WH | 1 |
| Bowen, DM; Francis, PT; Middlemiss, DN; Pangalos, MN; Pearson, RC; Stratmann, GC | 1 |
| Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D | 1 |
| Feniuk, W; Humphrey, PP; Perren, MJ | 1 |
| Ewing, FE; Furman, JS; Heym, JH; Howard, HR; Lowe, JA; Nagel, AA; Newman, ME; Schmidt, AW; Seeger, TF; Seymour, PA | 1 |
| Anderson, JM; Balfour, DJ; Benwell, ME | 1 |
| Deliganis, AV; Peroutka, SJ; Pierce, PA | 1 |
| Barzizza, A; Folghera, S; Maura, G; Raiteri, M | 1 |
| Fone, KC; Marsden, CA; Robinson, AJ | 1 |
| Cerruti, C; Marlier, L; Privat, A; Teilhac, JR | 1 |
| Baimbridge, KG; Klancnik, JM; Obenaus, A; Phillips, AG | 1 |
| Carbone, R; Guido, M; Maura, G; Pestarino, M; Raiteri, M | 1 |
| Ulrichsen, J | 1 |
| Baudrie, V; Chaouloff, F; Laude, D | 1 |
| Bird, ED; Crino, PB; Plager, MD; Vogt, BA | 1 |
| Bennett, DA; Glaeser, BS; Hutchison, AJ; Liebman, JM; Lovell, RA; Sills, MA; Williams, M; Wood, PL | 1 |
| Debler, EA; Lipovac, MN; Schlecht, MF; Tsarouhtsis, D | 1 |
| Anderson, SM; Elphick, M; Grahame-Smith, DG; Hallis, KF | 1 |
| Ashby, CR; Jiang, LH; Kasser, RJ; Wang, RY | 1 |
| Drummer, D; Lerer, B; Newman, ME | 1 |
| Eison, AS; Margraf, RR; Wright, RN; Yocca, FD | 1 |
| Geyer, MA; Tapson, GS; Wing, LL | 1 |
| Backus, LI; Grahame-Smith, DG; Sharp, T | 1 |
| Darmani, NA; Glennon, RA; Martin, BR; Pandey, U | 1 |
| Akaike, N; Murase, K; Nakagawa, T; Randic, M; Shirasaki, T | 1 |
| Jackson, DA; White, SR | 1 |
| Adams, RJ; Aronstam, RS; Martin, DC | 1 |
| Battista, PJ; Condon, WA; Rexroad, CE | 1 |
| Hellstrand, K; Hermodsson, S | 1 |
| Ramage, AG | 1 |
| Gillis, RA; Hamosh, P; Hill, KJ; Kellar, KJ; Kirby, JS; Norman, WP; Quest, JA | 1 |
| Bom, AH; Saxena, PR; Verdouw, PD | 1 |
| Arnt, J; Hyttel, J | 1 |
| Adler-Graschinsky, E; Butta, NV; Elgoyhen, AB | 1 |
| Nanry, KP; Tilson, HA | 1 |
| Hashimoto, T; Katsura, M; Koda, H; Kuriyama, K | 1 |
| Cook, LL; Reiter, LW; Sheets, LP | 1 |
| Coscia, EC; Daw, NW; Parkinson, D | 1 |
| Docherty, JR | 1 |
| Brown, CM; Kilpatrick, AT; MacKinnon, AC; Spedding, M | 1 |
| Chaouloff, F; Jeanrenaud, B | 1 |
| Barrett, JE; Bolger, GT; Mansbach, RS; Skolnick, P; Weissman, B; Witkin, JM | 1 |
| Beck, SG; Clarke, WP; Goldfarb, J | 1 |
| Engel, G; Hoyer, D; Kalkman, HO | 1 |
| Hibert, M; Middlemiss, DN | 1 |
| Gudelsky, GA; Koenig, JI; Meltzer, HY | 2 |
| Gole, D; Kreiman, MA; Ram, JL | 1 |
| Houston, DS; Vanhoutte, PM | 1 |
| Gilbert, MJ; Newberry, NR | 1 |
| Maura, G; Raiteri, M; Roccatagliata, E; Ulivi, M | 1 |
| el-Yassir, N; Fleetwood-Walker, SM; Mitchell, R | 1 |
| Aihara, H; Araki, H; Chaki, S; Muramatsu, M; Tamaki-Ohashi, J; Usuki, C | 1 |
| Bockaert, J; Kemp, DE; Sebben, M; Weiss, S | 1 |
| Björklund, M; Jäkälä, P; Kaukua, J; Koivisto, E; Riekkinen, P; Sirviö, J | 1 |
| Fiorella, D; Johnson, RG; Rabin, RA | 1 |
| Burnet, PW; Eastwood, SL; Harrison, PJ | 2 |
| Gower, AJ; Kendall, DA; Marsden, CA; Robson, L | 1 |
| Martin, GR; Mills, A | 1 |
| Hirayama, T; Kikuchi, K; Morita, K; Ogawa, Y; Onodera, S; Takeda, A; Takenaka, T; Tobise, K | 1 |
| Dondi, M; Pini, LA; Sandrini, M; Vitale, G | 1 |
| Blanchard, DC; Blanchard, RJ; McEwen, BS; McKittrick, CR; Sakai, RR | 1 |
| Miyamoto, A; Nishio, A; Sakota, T | 1 |
| Riekkinen, P | 1 |
| Katusić, ZS; Krstić, MK | 1 |
| Klimek, V; Papp, M; Willner, P | 1 |
| Kolpakov, VG; Kozintsev, I; Kulikov, AV; Maslova, GB; Popova, NK | 1 |
| Calabrese, JR; Khaitan, L; Stockmeier, CA | 1 |
| Butterworth, RF; Rao, VL | 1 |
| Cools, AR; Ellenbroek, BA; Prinssen, EP | 1 |
| Bielecka, Z; Bojarski, AJ; Boksa, J; Maćkowiak, M; Mokrosz, JL | 1 |
| Arranz, B; Eriksson, A; Marcusson, J; Mellerup, E; Plenge, P | 2 |
| Sillar, KT; Wedderburn, JF | 1 |
| Huang, X; Marona-Lewicka, D; Nichols, DE; Pfaff, RC | 1 |
| Bansse, MT; Stam, NJ; van Huizen, F | 1 |
| Damaj, MI; Glennon, RA; Martin, BR | 1 |
| Berg, M; Johansson-Wallsten, CE; Meyerson, BJ | 1 |
| Battaglia, G; Pinto, W | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Bojarski, AJ; Cegła, MT; Charakchieva-Minol, S; Maćkowiak, M; Misztal, S; Mokrosz, JL; Mokrosz, MJ | 1 |
| Davis, JM; Javaid, JI; Pandey, SC; Sahni, SK | 1 |
| Goldman, D; Hulihan-Giblin, BA; Pivorun, EB | 1 |
| Arneklo-Nobin, B; Bodelsson, M; Törnebrandt, K | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS; Murnion, B | 1 |
| Grignaschi, G; Mantelli, B; Samanin, R | 1 |
| Arita, H; Ichikawa, K; Sakamoto, M | 1 |
| Bobirnac, I; Schoeffter, P | 1 |
| Crick, H; Manuel, NA; Wallis, DI | 1 |
| Fletcher, A; Marsden, CA; Mundey, MK | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Marona-Lewicka, D; Monte, AP; Nelson, DL; Nichols, DE; Parker, MA; Wainscott, DB | 1 |
| Butterworth, RF; Mousseau, DD; Rao, VL | 1 |
| Burnet, PW; Chen, CP; Franklin, M; Harrison, PJ; McGowan, S | 1 |
| Austin, RH; Borroni, E; Bourson, A; Monsma, FJ; Sleight, AJ | 1 |
| Friedman, E; Tilakaratne, N | 1 |
| Chauveau, J; Doyen, C; Hamon, M; Hauw, JJ; Laporte, AM; Nevo, IT | 1 |
| Pini, LA; Sandrini, M; Vitale, G | 1 |
| Imamura, K; Muguruma, K; Watanabe, Y | 1 |
| Clayton, RA; MacLean, MR; Morecroft, I; Templeton, AG | 1 |
| Ichikawa, J; Meltzer, HY; Sumiyoshi, T | 1 |
| Aguerre, S; Berton, O; Chaouloff, F; Kulikov, A; Mormede, P; Ramos, A | 1 |
| Deschaux, P; Ferriere, F; Khan, NA; Meyniel, JP | 1 |
| Bigl, V; Heider, M; Rossner, S; Schliebs, R | 1 |
| Charakchieva-Minol, S; Chojnacka-Wójcik, E; Dereń-Wesołek, A; Duszyńska, B; Kowalska, T; Kowalski, P; Kłodzińska, A; Majka, Z; Misztal, S; Mokrosz, JL; Mokrosz, MJ; Tatarczyńska, E | 1 |
| Assié, MB; Kleven, MS; Koek, W | 1 |
| Barnes, PJ; Chung, KF; Stone, RA | 1 |
| Kitamura, Y; Nagatani, T; Takao, K; Yamawaki, S | 1 |
| Hagino, Y; Kaichi, Y; Kodama, Y; Nonaka, R; Watanabe, M | 1 |
| Crews, FT; Knapp, DJ; Overstreet, DH | 1 |
| Chairungsrilerd, N; Furukawa, K; Kisara, K; Ohizumi, Y; Tadano, T | 1 |
| Freier, D; Jähkel, M; Oehler, J; Rilke, O | 1 |
| Gean, PW; Lu, KT | 1 |
| Pearce, WJ; Purdy, R; Teng, GQ; Williams, J; Zhang, L | 1 |
| Dun, NJ; Hwang, LL | 1 |
| Burrows, GD; McGrath, C; Norman, TR | 1 |
| Hensler, JG; Truett, KA | 1 |
| De Leyn, P; Demedts, MG; Deneffe, G; Dupont, LJ; Pype, JL; Verleden, GM | 1 |
| Aguerre, S; Chaouloff, F; Mormede, P | 1 |
| Alder, JT; Bray, L; Chen, CP; Foster, OJ; Francis, PT; Kingsbury, AE | 1 |
| Kitchen, I; Mehta, S | 1 |
| Abe, S; Baba, A; Hori, T; Shiraishi, H; Suzuki, T; Yamamoto, T | 1 |
| Jeanningros, R; Kulikov, A; Moreau, X | 1 |
| Bard, JA; Branchek, T; Edvinsson, L; Longmore, J; Nilsson, T; Pantev, E; Shaw, D | 1 |
| Bult, H; Geerts, IS; Herman, AG; Matthys, KE | 1 |
| Ferrari, PF; Greengrass, P; Horton, RW; Lowther, S; Tidbury, H; Wilson, CA | 1 |
| Alfaro, MJ; Goicoechea, C; Martín, MI; Ormazábal, MJ; Sánchez, E | 1 |
| Browning, KN; Travagli, RA | 1 |
| Cousins, MS; Overstreet, DH; Seiden, LS; Vosmer, G | 1 |
| Barker, JL; Ma, W; Rubinow, DR; Zhang, L | 1 |
| Deis, RP; Hole, D; Jahn, GA; Kalia, V; Wilson, CA | 1 |
| Kulkarni, SK; Ninan, I | 1 |
| Dunn, AJ; Swiergiel, AH | 1 |
| Bonfante, V; Dall'Olio, R; Gaggi, R; Gandolfi, O | 1 |
| Placantonakis, DG; Schwarz, C; Welsh, JP | 1 |
| Dall'Olio, R; Gaggi, R; Gandolfi, O | 1 |
| Bisgard, GE; Herman, JK; O'Halloran, KD | 2 |
| Liang, SL; Pan, JT | 1 |
| Hayashi, Y; Hosokawa, M; Murayama, T; Nomura, Y; Oketani, Y; Okuma, Y; Ono, C; Onodera, T; Tha, KK; Watanabe, R | 1 |
| Fujio, M; Kuroita, T; Matsumoto, Y; Nakagawa, H; Sakai, Y | 1 |
| Borsini, F; Monferini, E; Scandroglio, A | 1 |
| Arai, Y; Hishinuma, T; Hozumi, M; Kinemuchi, H; Kisara, K; Mizugaki, M; Nakagawasai, O; Niijima, F; Oka, R; Satoh, N; Tadano, T; Tan-no, K; Yasuhara, H | 1 |
| Jeanningros, R; Mazzola-Pomietto, P; Moreau, X | 1 |
| Andorn, AC; Pappolla, MA | 1 |
| Audenaert, K; De Ley, G; De Vos, F; Dierckx, RA; Leysen, D; Slegers, G; Vandecapelle, M; Vermeirsch, H | 1 |
| Arai, Y; Indra, B; Kisara, K; Nakagawasai, O; Ohizumi, Y; Tadano, T; Yasuhara, H | 1 |
| Estrada-Camarena, E; López-Rubalcava, C; Martínez-Mota, L | 1 |
| Lograno, MD; Romano, MR | 1 |
| Saifullah, AS; Tomioka, K | 1 |
| Cocks, TM; Moffatt, JD; Page, CP | 1 |
| Menescal-de-Oliveira, L; Monassi, CR | 1 |
| McDonald, MD; Walsh, PJ | 1 |
| Cavaillon, JM; Cloëz-Tayarani, I; Fanburg, BL; Kayyali, US | 1 |
| Giarola, AS; Large, CH; Sokal, DM | 1 |
| Höglund, AU; Kommalage, M | 1 |
| Chandler, SH; Hsiao, CF; Wu, N | 1 |
| Jazvinsćak Jembrek, M; Lazić, J; Pericić, D; Svob Strac, D | 1 |
| Centurión, D; Gupta, S; MaassenVanDenBrink, A; Mehotra, S; Sánchez-López, A; Villalón, CM | 1 |
| Ferrarese, AA; Leite-Panissi, CR; Menescal-de-Oliveira, L; Terzian, AL | 1 |
| Pericić, D; Strac, DS; Vlainić, J | 1 |
| Araki, H; Fujitani, Y; Gomita, Y; Kitagawa, K; Kitamura, Y; Sendou, T; Shibata, K | 1 |
| Balsamo, A; Betti, L; Giannaccini, G; Nencetti, S; Orlandini, E; Rapposelli, S | 1 |
| Harris, MB; Kober, AM; Leiter, JC; St-John, WM; Toppin, VA | 1 |
| Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R | 1 |
| Günther, L; Jähkel, M; Liebscher, S; Oehler, J | 1 |
| Becnel, J; Johnson, O; Nichols, CD | 1 |
| Albrechet-Souza, L; Almada, RC; Borelli, KG; Brandão, ML | 1 |
| Anselmo-Franci, JA; Bícego, KC; de Souza Moreno, V; Gargaglioni, LH; Szawka, RE | 1 |
| Chen, CP; Esiri, MM; Francis, PT; Lai, MK; Tsang, SW; Wong, PT | 1 |
| Arango, V; Bakalian, MJ; Galfalvy, H; Kassir, SA; Mann, JJ; Underwood, MD | 1 |
| Baptista, D; Canto-de-Souza, A; Nunes-de-Souza, RL | 1 |
| Corcoran, AE; Harris, MB; Richerson, GB | 1 |
| de Paula, BB; Leite-Panissi, CR | 1 |
| Aronsen, D; Bukholt, N; Foote, J; Highgate, Q; Schenk, S; Van de Wetering, R; Webster, J | 1 |
| Barresi, M; Grasso, C; Li Volsi, G | 1 |
| Becegato, M; Bioni, VS; Cunha, DMG; Kurita, JPF; Leão, AHFF; Lima, AC; Lopes-Silva, LB; Marinho, GF; Paiva-Santos, MA; Ribeiro, AM; Silva, RH; Wuo-Silva, R | 1 |
4 review(s) available for ketanserin and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Structure-activity relationships of serotonin 5-HT
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship | 2019 |
Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors.
Topics: Brain; Humans; Ligands; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Serotonin | 2022 |
222 other study(ies) available for ketanserin and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection | 1992 |
High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[1-tetralin)alkyl]piperazines. 2.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; Isomerism; Kinetics; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1995 |
Cloning and characterisation of the human 5-HT5A serotonin receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection | 1994 |
1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cell Line; Discrimination, Psychological; Frontal Lobe; Hippocampus; Iodine Radioisotopes; Ketanserin; Male; Mice; Phenethylamines; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tritium | 1994 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Iodine Radioisotopes; Ligands; Rats; Receptors, Serotonin; Stereoisomerism; Tetrahydronaphthalenes; Tritium | 1993 |
Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Ketanserin; Male; Molecular Structure; Naphthalenes; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone; Structure-Activity Relationship; Tritium | 1994 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3.
Topics: Animals; Buspirone; Mass Spectrometry; Molecular Structure; Piperazines; Protein Binding; Rats; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists | 1996 |
Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Topics: Animals; Hippocampus; Ketanserin; Phencyclidine; Piperidines; Rats; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, sigma; Spiperone; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Structure-activity relationship studies on the 5-HT(1A) receptor affinity of 1-phenyl-4-[omega-(alpha- or beta-tetralinyl)alkyl]piperazines. 4.
Topics: Magnetic Resonance Spectroscopy; Piperazines; Radioligand Assay; Receptors, Serotonin; Structure-Activity Relationship | 1996 |
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents | 1996 |
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 1997 |
Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist.
Topics: Benzamides; Binding, Competitive; Gene Expression; HeLa Cells; Humans; Kinetics; Ligands; Pyridines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Tritium | 1997 |
Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719.
Topics: Adenylyl Cyclases; Cell Line; Cloning, Molecular; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Piperidines; Protein Binding; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Sulfonamides | 1998 |
N-[[1-(2-phenylethyl)pyrrolidin-2-yl]methyl]cyclohexanecarboxamides as selective 5-HT1A receptor agonists.
Topics: Amides; Animals; Binding, Competitive; In Vitro Techniques; Neurons; Pyrrolidines; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2000 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tetrahydronaphthalenes | 2007 |
1-Aminocyclopentane-1,2,4-tricarboxylic acids screening on glutamatergic and serotonergic systems.
Topics: Animals; Cells, Cultured; Cyclopentanes; Drug Evaluation, Preclinical; Humans; Molecular Structure; Rats; Receptors, Glutamate; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Tricarboxylic Acids | 2007 |
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.
Topics: Animals; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Indoles; Ligands; Male; Microwaves; Piperazine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 2010 |
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase | 2011 |
New potent 5-HT(2A) receptor ligands containing an N'-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation.
Topics: Amides; Animals; Drug Design; Ligands; Male; Picolinic Acids; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Stereoisomerism; Substrate Specificity | 2012 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.
Topics: Analgesics; Animals; Binding, Competitive; Cyclic AMP; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; HeLa Cells; Heterocyclic Compounds, 2-Ring; Humans; Hydantoins; Kinetics; Ligands; Male; Mice; Models, Chemical; Molecular Structure; Pain; Pain Measurement; Piperazines; Pyridines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists | 2013 |
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 2014 |
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming | 2015 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin | 2017 |
Genomic organization, coding sequence and functional expression of human 5-HT2 and 5-HT1A receptor genes.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cyclic AMP; Gene Expression; Genes; GTP-Binding Proteins; Humans; Inositol Phosphates; Ketanserin; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin; Transfection | 1992 |
Role of 5-hydroxytryptamine receptors on luteinizing-hormone-releasing hormone release in the ovariectomized, estradiol-treated rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ergolines; Estradiol; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Ketanserin; Ovariectomy; Pindolol; Preoptic Area; Quipazine; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin Antagonists; Suprachiasmatic Nucleus; Tetrahydronaphthalenes | 1992 |
Role of serotonin receptor subtype in seizures kindled from the feline hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anticonvulsants; Cats; Electric Stimulation; Female; Hallucinogens; Hippocampus; Ketanserin; Kindling, Neurologic; Male; Receptors, Serotonin; Seizures; Tetrahydronaphthalenes | 1992 |
Diverse actions of 5-hydroxytryptamine on frog spinal dorsal horn neurons in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dioxanes; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Ketanserin; Kinetics; Male; Membrane Potentials; Methysergide; Mianserin; Neurons; Rana pipiens; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Synapses; Tetrodotoxin; Tropanes | 1992 |
Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Brain; Cerebral Ventricles; Conditioning, Operant; Conflict, Psychological; Ergolines; Exploratory Behavior; Feeding Behavior; Injections, Intraventricular; Ketanserin; Learning; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Rats; Receptors, Serotonin; Seizures; Serotonin; Serotonin Antagonists | 1992 |
Regional analysis of 5-HT1A and 5-HT2 receptors in the fawn-hooded rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Ketanserin; Male; Platelet Storage Pool Deficiency; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin | 1992 |
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Ketanserin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Rabbits; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Fluoxetine and 8-OH-DPAT in the lateral septum enhances and impairs retention of an inhibitory avoidance response in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Brain Mapping; Dose-Response Relationship, Drug; Fear; Fluoxetine; Injections; Ketanserin; Male; Mental Recall; Rats; Rats, Inbred Strains; Receptors, Serotonin; Retention, Psychology; Ritanserin; Septum Pellucidum; Tetrahydronaphthalenes; Zimeldine | 1992 |
5-Hydroxytryptamine1A but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Glycoproteins; Ketanserin; Male; N-Glycosyl Hydrolases; Plant Lectins; Plant Proteins; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ribosome Inactivating Proteins, Type 2; Tetrahydronaphthalenes | 1992 |
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; In Vitro Techniques; Indoles; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Renal Artery; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Sympathectomy; Tetrahydronaphthalenes; Tyramine; Vasoconstrictor Agents; Vasodilation | 1991 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents | 1991 |
1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Dopamine Antagonists; Haloperidol; Ketanserin; Locomotion; Male; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetrahydronaphthalenes | 1991 |
Smoking-associated changes in the serotonergic systems of discrete regions of human brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Aged, 80 and over; Binding, Competitive; Brain Chemistry; Female; Hippocampus; Humans; Hydroxyindoleacetic Acid; Ketanserin; Male; Middle Aged; Serotonin; Smoking; Tetrahydronaphthalenes | 1990 |
Differential interactions of dimethyltryptamine (DMT) with 5-HT1A and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Guanosine Triphosphate; Ketanserin; N,N-Dimethyltryptamine; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Release of endogenous aspartate from rat cerebellum slices and synaptosomes: inhibition mediated by a 5-HT2 receptor and by a 5-HT1 receptor of a possibly novel subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Aspartic Acid; Calcium; Cerebellum; Ketanserin; Male; Methiothepin; Potassium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes | 1991 |
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, Spinal; Ketanserin; Male; Motor Activity; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1991 |
Autoradiographic mapping of 5-HT1, 5-HT1A, 5-HT1B and 5-HT2 receptors in the rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Iodine Radioisotopes; Iodocyanopindolol; Ketanserin; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tritium | 1991 |
The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Ketanserin; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1991 |
5-HT2 presynaptic receptors mediate inhibition of glutamate release from cerebellar mossy fibre terminals.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Calcium; Cerebellum; Glutamates; In Vitro Techniques; Ketanserin; Male; Microscopy, Electron; Nerve Endings; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes; Tetrodotoxin | 1991 |
Alterations in serotonin receptor subtypes in ethanol-dependent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Animals; Brain; Ethanol; Ketanserin; Pindolol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Evidence that 5-HT1A receptors are involved in the adrenaline-releasing effects of 8-OH-DPAT in the conscious rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Glucose; Epinephrine; Ketanserin; Male; Naphthalenes; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1990 |
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Autoradiography; Cerebral Cortex; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Humans; Iodocyanopindolol; Ketanserin; Male; Middle Aged; Oxotremorine; Paroxetine; Pindolol; Piperidines; Pirenzepine; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
CGS 18102A, a benzopyranopyridine anxiolytic with 5-HT1 agonist and 5-HT2 antagonist properties.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzopyrans; Binding, Competitive; Cerebral Cortex; Ketanserin; Kinetics; Piperidines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Synthesis and serotonin binding site studies of some conformationally restricted indolylethylamine analogues based on 2-amino-3-(3'-indolyl)bicyclo[2.2.2]octane.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Chemistry, Physical; Indoles; Ketanserin; Mice; Molecular Conformation; Molecular Structure; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes; Thermodynamics | 1990 |
Effects of carbamazepine on 5-hydroxytryptamine function in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Carbamazepine; Ketanserin; Male; Mice; Mice, Inbred C57BL; Models, Biological; Potassium; Serotonin; Tetrahydronaphthalenes; Tranylcypromine; Tryptophan; Tryptophan Hydroxylase | 1990 |
Electrophysiological characterization of 5-hydroxytryptamine2 receptors in the rat medial prefrontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ergolines; Frontal Lobe; Ketanserin; Magnesium; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Sodium Glutamate; Tetrahydronaphthalenes | 1990 |
Single and combined effects of desimipramine and lithium on serotonergic receptor number and second messenger function in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Desipramine; In Vitro Techniques; Inositol Phosphates; Ketanserin; Lithium; Male; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Head; Ketanserin; Male; Naphthalenes; Pindolol; Pyrimidines; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
5HT-2 mediation of acute behavioral effects of hallucinogens in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Ketanserin; Male; Mescaline; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Tetrahydronaphthalenes | 1990 |
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
Do functional relationships exist between 5-HT1A and 5-HT2 receptors?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Ketanserin; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred ICR; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Stereoisomerism; Tetrahydronaphthalenes | 1990 |
Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Synergism; Glycine; In Vitro Techniques; Indoles; Kainic Acid; Ketanserin; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropisetron | 1990 |
Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; In Vitro Techniques; Injections, Intravenous; Iontophoresis; Ketanserin; Male; Methysergide; Microelectrodes; Motor Neurons; Piperidines; Prazosin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes | 1990 |
The influence of isoflurane on the synaptic activity of 5-hydroxytryptamine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cell Membrane; Hippocampus; Isoflurane; Ketanserin; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes | 1990 |
Mechanisms involved in the action of serotonin-induced stimulation of progesterone production by bovine luteal cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cattle; Corpus Luteum; Estrus; Female; In Vitro Techniques; Ketanserin; Mianserin; Progesterone; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1987 |
Role of serotonin in the regulation of human natural killer cell cytotoxicity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cyproheptadine; Cytotoxicity, Immunologic; Drug Synergism; Humans; Interferons; Ketanserin; Killer Cells, Natural; Lymphocyte Culture Test, Mixed; Lymphokines; Monocytes; Receptors, Serotonin; Serotonin; Stimulation, Chemical; Tetrahydronaphthalenes | 1987 |
Are drugs that act both on serotonin receptors and alpha 1-adrenoceptors more potent hypotensive agents than those that act only on alpha 1-adrenoceptors?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Cinanserin; Ergolines; Ketanserin; Male; Metergoline; Piperidines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1988 |
Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Brain; Cats; Dioxanes; Female; Heart Rate; Ketanserin; Male; Piperazines; Receptors, Serotonin; Respiration; Tetrahydronaphthalenes; Uracil | 1989 |
Carotid haemodynamics in pigs during infusions of 8-OH-DPAT: reduction in arteriovenous shunting is mediated by 5-HT1-like receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriovenous Anastomosis; Blood Pressure; Carotid Arteries; Heart Rate; Hemodynamics; Infusions, Intra-Arterial; Ketanserin; Methiothepin; Microspheres; Naphthalenes; Receptors, Serotonin; Swine; Tetrahydronaphthalenes | 1989 |
Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Injections, Subcutaneous; Ketanserin; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes | 1989 |
Different receptor subtypes mediate the dual presynaptic effects of 5-hydroxytryptamine on peripheral sympathetic neurones.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Cyproheptadine; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Ketanserin; Male; Membranes; Metoclopramide; Neurons; Norepinephrine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes; Tropanes | 1989 |
The role of 5HT1A receptors in the modulation of the acoustic startle reflex in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Metergoline; Methoxydimethyltryptamines; Quipazine; Rats; Rats, Inbred F344; Receptors, Serotonin; Reflex, Startle; Serotonin Antagonists; Tetrahydronaphthalenes | 1989 |
Effect of (+/-)-methyl 3-ethyl-2,3,3a,4-tetrahydro-1H-indolo-[3,2,1-de] [1,5] naphthyridine-6-carboxylate hydrochloride (OM-853), a new vincamine analogue, on the metabolism and function of cerebral serotonergic neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Animals; Brain; Brain Chemistry; Corpus Striatum; Ketanserin; Male; Neurons; Potassium Chloride; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Vinca Alkaloids; Vincamine | 1989 |
Serotonergic modulation of the acoustic startle response in rats during preweaning development.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Age Factors; Animals; Animals, Suckling; Brain Chemistry; Cyproheptadine; Dopamine; Dose-Response Relationship, Drug; Female; Fenclonine; Ketanserin; Male; Methoxydimethyltryptamines; Norepinephrine; Piperazines; Rats; Reflex, Startle; Serotonin; Tetrahydronaphthalenes | 1989 |
Identification and localization of 5-hydroxytryptamine receptor sites in macaque visual cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Chromatography, High Pressure Liquid; Female; Ketanserin; Macaca nemestrina; Male; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tissue Distribution; Visual Cortex | 1989 |
An investigation of the effects of intravenous injection of the 5-hydroxytryptamine 2 receptor antagonists ketanserin and LY 53857 on blood pressure in anesthetized spontaneously hypertensive rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Pressure; Ergolines; Heart Rate; Hypertension; Ketanserin; Male; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Xylazine | 1989 |
The alpha 2-adrenoceptor antagonist SK&F 104078 has high affinity for 5-HT1A and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Tetrahydronaphthalenes | 1989 |
5-HT1A and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n-propylamino)tetralin in the conscious rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Brain; Fasting; Insulin; Ketanserin; Male; Naphthalenes; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reserpine; Tetrahydronaphthalenes | 1987 |
Behavioral studies with anxiolytic drugs. IV. Serotonergic involvement in the effects of buspirone on punished behavior of pigeons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Dose-Response Relationship, Drug; Ketanserin; Male; Punishment; Pyrazines; Pyrimidines; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Tritium | 1987 |
Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Butyrophenones; Hippocampus; In Vitro Techniques; Ketanserin; Piperidines; Rats; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1985 |
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Choroid Plexus; Ergolines; In Vitro Techniques; Iodocyanopindolol; Ketanserin; Male; Membranes; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tetrahydronaphthalenes | 1985 |
Stereoselective blockade at the 5-HT autoreceptor and inhibition of radioligand binding to central 5-HT recognition sites by the optical isomers of methiothepin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dibenzothiepins; Frontal Lobe; In Vitro Techniques; Ketanserin; Male; Methiothepin; Piperidines; Rats; Receptors, Serotonin; Serotonin; Stereoisomerism; Tetrahydronaphthalenes | 1986 |
Discriminative stimulus properties of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH DPAT).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ketanserin; Male; Naphthalenes; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1986 |
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Ketanserin; Male; Methoxydimethyltryptamines; Pindolol; Piperidines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1986 |
Stimulation of corticosterone and beta-endorphin secretion in the rat by selective 5-HT receptor subtype activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; beta-Endorphin; Corticosterone; Endorphins; Ketanserin; Male; Pindolol; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes | 1987 |
LY165163 and 8-OH-DPAT have agonist effects on a serotonin responsive muscle of Aplysia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperazines; Serotonin; Tetrahydronaphthalenes | 1987 |
Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ketanserin; Male; Metergoline; Methiothepin; Muscle, Smooth, Vascular; Pindolol; Receptors, Serotonin; Tetrahydronaphthalenes; Vasodilation | 1988 |
A 5-HT1-like receptor mediates a sympathetic ganglionic hyperpolarization.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ganglia, Sympathetic; In Vitro Techniques; Ketanserin; Membrane Potentials; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tropanes | 1987 |
Serotonin-glutamate interaction in rat cerebellum: involvement of 5-HT1 and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Calcium; Cerebellum; Glutamates; In Vitro Techniques; Ketanserin; Male; Methiothepin; Potassium; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1988 |
Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Indoles; Ketanserin; Male; Neurons, Afferent; Pain; Physical Stimulation; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes | 1988 |
5-HT2 antagonists and minaprine block the 5-HT-induced inhibition of dopamine release from rat brain striatal slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Corpus Striatum; Dopamine; In Vitro Techniques; Ketanserin; Male; Medial Forebrain Bundle; Membranes; Pyridazines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tetrahydronaphthalenes | 1988 |
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; Fetus; Indoles; Ketanserin; Metergoline; Mice; Neurons; Piperidines; Pregnancy; Receptors, Serotonin; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide | 1986 |
Modulation of rat neocortical high-voltage spindle activity by 5-HT1/5-HT2 receptor subtype specific drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Cerebral Cortex; Electroencephalography; Infusions, Parenteral; Ketanserin; Male; Methiothepin; Methysergide; Neural Pathways; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Thalamus | 1995 |
Effects of chronic cocaine administration on the serotonergic system in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 1993 |
Detection and quantitation of 5-HT1A and 5-HT2A receptor mRNAs in human hippocampus using a reverse transcriptase-polymerase chain reaction (RT-PCR) technique and their correlation with binding site densities and age.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aging; Amino Acid Isomerases; Base Sequence; Binding Sites; Carrier Proteins; Chaperonins; DNA Primers; Hippocampus; Humans; Ketanserin; Middle Aged; Molecular Sequence Data; Peptidylprolyl Isomerase; Polymerase Chain Reaction; Receptors, Serotonin; RNA-Directed DNA Polymerase; RNA, Messenger; Tritium | 1994 |
Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hydroxyindoleacetic Acid; Ketanserin; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1993 |
Autoradiographic mapping of [3H]sumatriptan binding in cat brain stem and spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Stem; Cats; Ketanserin; Male; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Spinal Cord; Sumatriptan; Trigeminal Nuclei | 1995 |
Comparison of 5-hydroxytryptamine-induced contraction of rat pulmonary artery to that of aorta in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Ketanserin; Male; Pindolol; Pulmonary Artery; Quinazolines; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Ritanserin; Serotonin; Vasoconstriction | 1995 |
Effects of acetylsalicylic acid on serotonin brain receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Aspirin; Brain Chemistry; Cerebral Cortex; Ketanserin; Male; Membranes; Pons; Rats; Rats, Wistar; Receptors, Serotonin | 1995 |
Serotonin receptor binding in a colony model of chronic social stress.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Autoradiography; Brain; Corticosterone; Dominance-Subordination; Female; Iodocyanopindolol; Ketanserin; Male; Pindolol; Rats; Receptors, Serotonin; Social Environment; Stress, Psychological | 1995 |
Characterization of 5-hydroxytryptamine receptors on the isolated pig basilar artery by functional and radioligand binding studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basilar Artery; Binding, Competitive; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Swine | 1994 |
5-HT1A and muscarinic acetylcholine receptors jointly regulate passive avoidance behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Choline O-Acetyltransferase; Drug Interactions; Ketanserin; Male; Motor Activity; Muscarinic Agonists; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin; Scopolamine; Septal Nuclei; Serotonin Receptor Agonists | 1994 |
Further evidence that the tachycardiac response to 5-hydroxytryptamine in rats is not mediated via typical 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Ergolines; Female; Heart Rate; Ketanserin; Male; Methiothepin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin | 1994 |
Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Dihydroalprenolol; Imipramine; Ketanserin; Kinetics; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Stress, Psychological | 1994 |
Effect of selective 5-HT1A agonists and 5-HT2 antagonists on inherited catalepsy in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Catalepsy; Dose-Response Relationship, Drug; Ketanserin; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Effects of chronic treatment with valproate on serotonin-1A receptor binding and function.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Brain Chemistry; Cerebral Cortex; Hippocampus; Ketanserin; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Valproic Acid | 1994 |
Alterations of [3H]8-OH-DPAT and [3H]ketanserin binding sites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Autopsy; Binding Sites; Brain; Hepatic Encephalopathy; Humans; Ketanserin; Liver Cirrhosis; Male; Middle Aged; Tissue Distribution; Tritium | 1994 |
The role of serotonin receptor subtypes in the behavioural effects of neuroleptic drugs. A paw test study in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Structure-activity relationship studies of CNS agents. Part 10(1): 1-Aryl-2-[3-(4-aryl-1-piperazinyl)propyl]-1,4-dihydro-3(2H)-isoquino linones: two modes of the interaction with the 5-HT1A receptor site.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; In Vitro Techniques; Isoquinolines; Ketanserin; Models, Molecular; Piperazines; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship | 1994 |
Brain 5-HT1A, 5-HT1D, and 5-HT2 receptors in suicide victims.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Age Factors; Brain; Depressive Disorder; Female; Frontal Lobe; Humans; Ketanserin; Male; Middle Aged; Organ Size; Receptors, Serotonin; Suicide | 1994 |
Modulation of rhythmic swimming activity in post-embryonic Xenopus laevis tadpoles by 5-hydroxytryptamine acting at 5HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Cyproheptadine; Ergolines; Ketanserin; Metamorphosis, Biological; Methysergide; Motor Activity; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Xenopus laevis | 1994 |
Drug discrimination and receptor binding studies of N-isopropyl lysergamide derivatives.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Binding, Competitive; Conditioning, Operant; Discrimination, Psychological; Hallucinogens; Iodine Radioisotopes; Ketanserin; Lysergic Acid Diethylamide; Male; Models, Molecular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement Schedule | 1994 |
Agonist-induced down-regulation of human 5-HT1A and 5-HT2 receptors in Swiss 3T3 cells.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Colforsin; Cyclic AMP; Down-Regulation; Humans; Hydrolysis; Ketanserin; Kinetics; Mice; Mice, Inbred Strains; Pertussis Toxin; Phosphatidylinositols; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Virulence Factors, Bordetella | 1993 |
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Ketanserin; Locomotion; Male; Mice; Mice, Inbred ICR; Nicotine; Nociceptors; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1994 |
The effects of long-term treatment with the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT2/1C receptor agonist DOI in the neonatal rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Ketanserin; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Vocalization, Animal | 1993 |
In vivo EEDQ dose-dependently inactivates rat brain 5-HT receptors but not 5-HT uptake sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Brain; Carrier Proteins; Cerebral Cortex; Dose-Response Relationship, Drug; Iodocyanopindolol; Ketanserin; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pindolol; Quinolines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 1993 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Structure-activity relationship studies of CNS agents. Part 9: 5-HT1A and 5-HT2 receptor affinity of some 2- and 3-substituted 1,2,3,4-tetrahydro-beta-carbolines.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain Chemistry; Carbolines; Cerebral Cortex; Hippocampus; In Vitro Techniques; Ketanserin; Rats; Receptors, Serotonin; Serotonin; Stereoisomerism; Structure-Activity Relationship | 1993 |
Effect of aging in human cortical pre- and postsynaptic serotonin binding sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Aging; Binding Sites; Female; Frontal Lobe; Humans; Ketanserin; Male; Middle Aged; Paroxetine; Radioligand Assay; Serotonin; Synapses | 1993 |
Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Hippocampus; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereotyped Behavior | 1993 |
Diurnal rhythms of 5-HT1A and 5-HT2 receptor binding in euthermic and torpor prone deermice, Peromyscus maniculatus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Brain Chemistry; Circadian Rhythm; Eating; Indicators and Reagents; Ketanserin; Kinetics; Membranes; Peromyscus; Radioligand Assay; Receptors, Serotonin; Sleep | 1993 |
Endothelial relaxing 5-hydroxytryptamine receptors in the rat jugular vein: similarity with the 5-hydroxytryptamine1C receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Endothelium, Vascular; Female; In Vitro Techniques; Jugular Veins; Ketanserin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Vasodilation | 1993 |
Excitation and inhibition of rat medial vestibular nucleus neurones by 5-hydroxytryptamine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Immunohistochemistry; Ketanserin; Male; Neurons; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Vestibular Nuclei | 1993 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Models, Animal; Feeding Behavior; Ketanserin; Male; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Ritanserin; Stress, Physiological | 1993 |
Serotonergic cells in nucleus raphe pallidus provide tonic drive to posterior cricoarytenoid motoneurons via 5-hydroxytryptamine2 receptors in cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Airway Obstruction; Animals; Cats; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electric Stimulation; Ketanserin; Laryngeal Muscles; Microinjections; Motor Neurons; Raphe Nuclei; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep, REM | 1995 |
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine | 1995 |
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan | 1995 |
Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Behavior, Animal; Carbidopa; Guinea Pigs; Ketanserin; Male; Neurons; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Dihydrobenzofuran analogues of hallucinogens. 3. Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Benzofurans; Binding, Competitive; Cell Membrane; Cricetinae; Hallucinogens; Hippocampus; Humans; Ketanserin; Lysergic Acid Diethylamide; Male; Mesocricetus; Molecular Conformation; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Structure-Activity Relationship; Tritium | 1996 |
Alterations in serotonin parameters in brain of thiamine-deficient rats are evident prior to the appearance of neurological symptoms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Autoradiography; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Feeding Behavior; Hydroxyindoleacetic Acid; Hypothermia; Ketanserin; Male; Monoamine Oxidase; Nervous System Diseases; Neurologic Examination; Pyrithiamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiamine Deficiency; Tritium | 1996 |
The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Organ Specificity; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values; RNA, Messenger; Serotonin; Transcription, Genetic; Tritium | 1996 |
Effects of altered 5-ht6 expression in the rat: functional studies using antisense oligonucleotides.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Base Sequence; Behavior, Animal; Binding, Competitive; In Vitro Techniques; Injections, Intraventricular; Ketanserin; Lysergic Acid Diethylamide; Male; Membranes; Molecular Sequence Data; Oligonucleotides, Antisense; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Genomic responses to 5-HT1A or 5-HT2A/2C receptor activation is differentially regulated in four regions of rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blotting, Northern; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; DNA Probes; Gene Expression; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Hippocampus; Ketanserin; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Autoradiographic mapping of serotonin 5-HT1A, 5-HT1D, 5-HT2A and 5-HT3 receptors in the aged human spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Aged, 80 and over; Aging; Autoradiography; Humans; Ketanserin; Ligands; Pain; Postmortem Changes; Receptors, Serotonin; Spinal Cord | 1996 |
Lack of activity of azapropazone in the hot-plate test and in 5-HT1A and 5-HT2 receptor subtypes in rat brain membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apazone; Binding, Competitive; Brain Chemistry; Ketanserin; Male; Membranes; Motor Activity; Pain Measurement; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Repeated peripheral administration of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin alters the binding activities of 5-HT1A and 5-HT2 receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biopterins; Brain; Ketanserin; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Tritium | 1996 |
Evidence for 5-HT1-like receptor-mediated vasoconstriction in human pulmonary artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Benzamides; Humans; In Vitro Techniques; Ketanserin; Kinetics; Methiothepin; Pulmonary Artery; Pyridines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction | 1996 |
5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Animals; Antipsychotic Agents; Autoradiography; Binding Sites; Brain; Female; Haloperidol; Humans; Ketanserin; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Schizophrenia | 1996 |
The effect of streptozotocin-induced diabetes on dopamine2, serotonin1A and serotonin2A receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diabetes Mellitus, Experimental; Dopamine Antagonists; Frontal Lobe; Haloperidol; Hippocampus; Ketanserin; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Streptozocin | 1997 |
Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Citalopram; Female; Hippocampus; Hydroxyindoleacetic Acid; Ketanserin; Male; Mesencephalon; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Receptors, Serotonin; Serotonin; Tritium; Tryptophan Hydroxylase | 1997 |
5-Hydroxytryptamine-induced calcium-channel gating in rainbow trout (Oncorhynchus mykiss) peripheral blood lymphocytes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Calcium Channels; Dopamine Antagonists; Ion Channel Gating; Ionomycin; Ionophores; Ketanserin; Lymphocytes; Metoclopramide; Oncorhynchus mykiss; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulpiride | 1997 |
Basal forebrain cholinergic immunolesion by 192IgG-saporin: evidence for a presynaptic location of subpopulations of alpha 2- and beta-adrenergic as well as 5-HT2A receptors on cortical cholinergic terminals.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholinesterase; Animals; Antibodies, Monoclonal; Autoradiography; Cerebral Cortex; Cholinergic Fibers; Dihydroalprenolol; Immunotoxins; Isotope Labeling; Ketanserin; Male; N-Glycosyl Hydrolases; Prazosin; Presynaptic Terminals; Prosencephalon; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ribosome Inactivating Proteins, Type 1; Saporins; Tritium; Yohimbine | 1997 |
5-HT1A and 5-HT2A receptor affinity and functional profile of some N-[3-(4-aryl-1-piperazinyl)propyl] derivatives of indolin-2(1H)-one, quinolin-2(1 H)-one and isoquinolin-1(2H)-one. Part 30: Structure-activity relationship studies of CNS agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Ketanserin; Kinetics; Male; Mice; Piperazines; Quinolones; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzopyrans; Discrimination, Psychological; Ketanserin; Lysergic Acid Diethylamide; Male; Nicotinic Acids; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Effect of 5-HT1A receptor agonist, 8-OH-DPAT, on cough responses in the conscious guinea pig.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cough; Guinea Pigs; Ketanserin; Male; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Respiration; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Inflammatory Agents; Behavior, Animal; Corticosterone; Frontal Lobe; Hippocampus; Ketanserin; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tremor | 1997 |
Effect of chronic amitriptyline administration on serotonergic receptors in rats with methylazoxymethanol-induced microencephaly.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkylating Agents; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebral Cortex; Female; Ketanserin; Kinetics; Male; Methylazoxymethanol Acetate; Microcephaly; Pregnancy; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Brain 5-HT1A receptor autoradiography and hypothermic responses in rats bred for differences in 8-OH-DPAT sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animal Husbandry; Animals; Autoradiography; Body Temperature; Brain; Drug Resistance; Hypothermia; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Selection, Genetic; Serotonin Antagonists | 1998 |
Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Injections, Intraventricular; Inositol Phosphates; Ketanserin; Male; Mice; Motor Activity; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tryptamines; Xanthenes; Xanthones | 1998 |
Dynamic alterations of serotonergic metabolism and receptors during social isolation of low- and high-active mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Hippocampus; Ketanserin; Kinetics; Male; Mesencephalon; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Isolation | 1998 |
Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Barium; Epilepsy; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Ketanserin; Male; Membrane Potentials; Metergoline; Neurons; Oxadiazoles; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1998 |
Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Carotid Artery, Common; Cerebral Arteries; Female; Ketanserin; Male; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sheep | 1998 |
5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Diphosphate; Ketanserin; Medulla Oblongata; Membrane Potentials; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Synaptic Transmission; Thionucleotides | 1998 |
Neurochemical effects of the enantiomers of mirtazapine in normal rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Body Temperature; Injections, Intraperitoneal; Ketanserin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism | 1998 |
Effect of chronic serotonin-2 receptor agonist or antagonist administration on serotonin-1A receptor sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Hypothermia; Ketanserin; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents | 1998 |
The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Capsaicin; Cholinergic Fibers; Culture Techniques; Cyclohexane Monoterpenes; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Humans; Indoles; Ketanserin; Methysergide; Muscle Contraction; Muscle, Smooth; Neuropeptides; Pindolol; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Trachea; Tropisetron | 1998 |
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase | 1998 |
Post-synaptic 5-HT1A and 5-HT2A receptors are increased in Parkinson's disease neocortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Humans; Ketanserin; Kinetics; Neocortex; Parkinson Disease; Paroxetine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values | 1998 |
Regional changes in 5-HT1A but not in 5-HT2A receptors in mouse brain after Semliki Forest virus infection: radioligand binding and autoradiographic studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alphavirus Infections; Animals; Autoradiography; Brain Chemistry; Brain Stem; Corticosterone; Hypothalamus; Image Processing, Computer-Assisted; Ketanserin; Male; Mice; Mice, Inbred BALB C; Nucleus Accumbens; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Semliki forest virus; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 1998 |
Effects of chronic administration of interferon alpha A/D on serotonergic receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Carrier Proteins; Cell Membrane; Cerebral Cortex; Hippocampus; Interferon Type I; Ketanserin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Tritium | 1999 |
Effects of experimental hypothyroidism on 5-HT1A, 5-HT2A receptors, 5-HT uptake sites and tryptophan hydroxylase activity in mature rat brain1.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Citalopram; Hypothyroidism; Ketanserin; Luminescent Measurements; Male; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thyroidectomy; Thyroxine; Triiodothyronine; Tryptophan Hydroxylase | 1999 |
Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cardiovascular System; Coronary Vessels; Dose-Response Relationship, Drug; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Ketanserin; Methiothepin; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tissue Distribution; Tryptamines; Vasoconstriction | 1999 |
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction | 1999 |
The influence of gender and age on neonatal rat hypothalamic 5-HT1A and 5-HT2A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amygdala; Animals; Animals, Newborn; Female; Gene Expression Regulation, Developmental; Hypothalamus; Ketanserin; Male; Nerve Tissue Proteins; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Sex Characteristics; Testosterone | 1999 |
Study of mechanisms of calcitonin analgesia in mice. Involvement of 5-HT3 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Brain Chemistry; Calcitonin; Dose-Response Relationship, Drug; Indoles; Indophenol; Ketanserin; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain; Pain Measurement; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1999 |
Characterization of the in vitro effects of 5-hydroxytryptamine (5-HT) on identified neurones of the rat dorsal motor nucleus of the vagus (DMV).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cesium; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Indoles; Intestines; Ketanserin; Ligands; Male; Membrane Potentials; Motor Neurons; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Stomach; Synaptic Transmission; Tropisetron; Vagus Nerve | 1999 |
Rats selectively bred for responsiveness to 5-hydroxytryptamine(1A) receptor stimulation: differences in differential reinforcement of low rate 72-second performance and response to serotonergic drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Age Factors; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hypothermia; Ketanserin; Male; Rats; Receptors, Serotonin; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |
Sex differences in expression of serotonin receptors (subtypes 1A and 2A) in rat brain: a possible role of testosterone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Autoradiography; Female; Gene Expression; Hypothalamus; In Situ Hybridization; Ketanserin; Male; Orchiectomy; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Sex Characteristics; Testosterone; Transcription, Genetic; Tritium | 1999 |
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamines; Analysis of Variance; Animals; Brain Chemistry; Dopamine; Female; Fenclonine; Fenfluramine; Gestational Age; Ketanserin; Metoprolol; Norepinephrine; p-Chloroamphetamine; Prazosin; Pregnancy; Pregnancy, Animal; Prolactin; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1999 |
Quinpirole, 8-OH-DPAT and ketanserin modulate catalepsy induced by high doses of atypical antipsychotics.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Benzodiazepines; Catalepsy; Clozapine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Indoles; Ketanserin; Male; Mice; Mice, Inbred BALB C; Olanzapine; Pirenzepine; Quinpirole; Random Allocation; Rats; Rats, Wistar; Risperidone; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity | 1999 |
Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Eating; Interleukin-1; Ketanserin; Lipopolysaccharides; Male; Mice; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sulfonamides | 2000 |
The non-competitive NMDA receptor blocker dizocilpine potentiates serotonergic function.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ketanserin; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sulpiride | 1999 |
Serotonin suppresses subthreshold and suprathreshold oscillatory activity of rat inferior olivary neurones in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Cardiovascular Agents; Electric Impedance; Electrophysiology; Ketanserin; Methysergide; Neurons; Olivary Nucleus; Periodicity; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Blockade of the serotonergic system counteracts the dizocilpine-induced changes in dopaminergic function.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Grooming; Ketanserin; Male; Methysergide; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2000 |
Serotonin and the hypoxic ventilatory response in awake goats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acclimatization; Animals; Carotid Body; Chemoreceptor Cells; Female; Goats; Hypoxia; Ketanserin; Methysergide; Oxygen; Respiration; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
An endogenous serotonergic rhythm acting on 5-HT(2A) receptors may be involved in the diurnal changes in tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Circadian Rhythm; Dihydroxyphenylalanine; Dopamine; Estrogens; Female; Ketanserin; Nerve Degeneration; Neurons; Ovariectomy; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence accelerated mouse (SAM)-P10.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Behavior, Animal; Benzazepines; Brain; Depression; Ketanserin; Male; Mice; Quinpirole; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 2000 |
N-[1-(2-Phenylethyl)pyrrolidin-3-yl]-1-adamantanecarboxamides as novel 5-HT2 receptor antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adamantane; Animals; Brain Chemistry; Ketanserin; Male; Molecular Structure; Platelet Aggregation Inhibitors; Pyrrolidines; Rabbits; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 2000 |
Effect of 8-OH DPAT and ketanserin on the ventilatory acclimatization to hypoxia in awake goats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Consciousness; Female; Goats; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Ketanserin; Pulmonary Ventilation; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tidal Volume | 2001 |
Ex vivo binding of flibanserin to serotonin 5-HT1A and 5-HT2A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzimidazoles; Brain; Dose-Response Relationship, Drug; Ketanserin; Male; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Central serotonergic mechanisms on head twitch response induced by benzodiazepine receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Dihydroxytryptamines; Estazolam; Fluoxetine; GABA-A Receptor Agonists; Hypnotics and Sedatives; Ketanserin; Male; Mice; Piperazines; Receptors, GABA-A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Triazolam | 2001 |
Chronic effects of triiodothyronine in combination with imipramine on 5-HT transporter, 5-HT(1A) and 5-HT(2A) receptors in adult rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain; Carrier Proteins; Citalopram; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Imipramine; Ketanserin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Thyroid Gland; Time Factors; Triiodothyronine | 2001 |
Catecholamines inhibit lipid peroxidation in young, aged, and Alzheimer's disease brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Aging; Alzheimer Disease; Autopsy; Brain; Catecholamines; Caudate Nucleus; Cerebellum; Dopamine; Haloperidol; Humans; Ketanserin; Lipid Peroxidation; Melatonin; Middle Aged; Postmortem Changes; Prefrontal Cortex; Putamen; Serotonin; Thiobarbituric Acid Reactive Substances | 2001 |
In vivo evaluation of 4-[123I]iodo-N-[2[4-(6-trifluoromethyl-2-pyridinyl)-1-piperazinyl]ethyl]benzamide, a potential SPECT radioligand for the 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Brain; Ketanserin; Male; Piperazines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2001 |
Suppressive effect of nantenine, isolated from Nandina domestica Thunberg, on the 5-hydroxy-L-tryptophan plus clorgyline-induced head-twitch response in mice.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aporphines; Brain; Clorgyline; Fruit; Ketanserin; Male; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Movement Disorders; Plant Extracts; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Indorenate produces antidepressant-like actions in the rat forced swimming test via 5-HT1A receptors.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Buspirone; Dose-Response Relationship, Drug; Drug Interactions; Ketanserin; Male; Motor Activity; Pindolol; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 2002 |
Pharmacological characterization of the 5-HT1A, 5-HT2 and 5-HT3 receptors in the bovine ciliary muscle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cattle; Cell Membrane; Ciliary Body; Dose-Response Relationship, Drug; Granisetron; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle, Smooth; Ondansetron; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 2003 |
5-HT(7)-like receptors mediate serotonergic modulation of photo-responsiveness of the medulla bilateral neurons in the cricket, Gryllus bimaculatus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Colforsin; Dose-Response Relationship, Drug; Electrophysiology; Gryllidae; Ketanserin; Light; Neurons; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Visual Pathways | 2003 |
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum Toxins, Type A; Calcium Channel Blockers; Calcium Channels; Cartilage; Electric Stimulation; Epithelial Cells; Epithelium; Female; Ganglia, Parasympathetic; Inositol 1,4,5-Trisphosphate Receptors; Ketanserin; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Receptors, Cytoplasmic and Nuclear; Serotonin; Surface-Active Agents; Tetrodotoxin; Trachea | 2004 |
Serotonin 5-HT2 and 5-HT1A receptors in the periaqueductal gray matter differentially modulate tonic immobility in guinea pig.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Immobilization; Ketanserin; Male; Microinjections; Neural Networks, Computer; Periaqueductal Gray; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Dogmas and controversies in the handling of nitrogenous wastes: 5-HT2-like receptors are involved in triggering pulsatile urea excretion in the gulf toadfish, Opsanus beta.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Batrachoidiformes; Biological Transport; Dose-Response Relationship, Drug; Hydrocortisone; Ketanserin; Polyethylene Glycols; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin 5-HT2 Receptor Agonists; Time Factors; Tritium; Urea | 2004 |
5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fluoxetine; Humans; Immunologic Factors; Ketanserin; Leukocytes, Mononuclear; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2004 |
Effects of GABA(B), 5-HT(1A), and 5-HT(2) receptor stimulation on activation and inhibition of the rat lateral amygdala following medial geniculate nucleus stimulation in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Amygdala; Animals; Anxiety; Baclofen; Evoked Potentials; GABA Agonists; Geniculate Bodies; Ketanserin; Male; Neural Pathways; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, GABA-B; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Involvement of spinal serotonin receptors in the regulation of intraspinal acetylcholine release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Amphetamines; Animals; Biguanides; Citalopram; Dose-Response Relationship, Drug; Ketanserin; Male; Microdialysis; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors | 2005 |
Voltage-dependent calcium currents in trigeminal motoneurons of early postnatal rats: modulation by 5-HT receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Neural Inhibition; Patch-Clamp Techniques; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trigeminal Nuclei | 2005 |
Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Drug Administration Schedule; Drug Therapy, Combination; Ketanserin; Male; Mice; Mice, Inbred CBA; Picrotoxin; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Seizures; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological; Swimming | 2005 |
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buspirone; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Ergotamine; Heart Rate; Ketanserin; Lisuride; Male; Metergoline; Methiothepin; Methysergide; Phenylephrine; Piperazines; Pizotyline; Prazosin; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 2006 |
Serotoninergic activation of the basolateral amygdala and modulation of tonic immobility in guinea pig.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Guinea Pigs; Immobility Response, Tonic; Ketanserin; Male; Microinjections; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Zimelidine decreases seizure susceptibility in stressed mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Behavior, Animal; Convulsants; Ketanserin; Male; Mianserin; Mice; Mice, Inbred CBA; Phenols; Picrotoxin; Piperazines; Pyridines; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Sulfonamides; Swimming; Zimeldine | 2006 |
The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Body Temperature; Brain; Dose-Response Relationship, Drug; Hypothermia; Ketanserin; Male; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Tremor | 2007 |
Synthesis and 5-HT2A, 5-HT1A and alpha1-binding affinities of 2-[2-Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-hydroxy-3-(2-pyridin-2-yl-ethyl)amino]- and 2-[2-hydroxy-3-(4-N-methyl-piperazin-1-yl)-amino]propoxybenzaldehyde-O-(substituted) benzyl oximes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Ketanserin; Ligands; Molecular Structure; Oximes; Piperazines; Prazosin; Protein Binding; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Succinates | 2007 |
Persistence of eupnea and gasping following blockade of both serotonin type 1 and 2 receptors in the in situ juvenile rat preparation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Decerebrate State; Disease Models, Animal; Dose-Response Relationship, Drug; Hypoglossal Nerve; Ischemia; Ketanserin; Lung; Methysergide; Peripheral Nerves; Phrenic Nerve; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin, 5-HT1; Respiratory Mechanics; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Vagus Nerve | 2007 |
Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Anxiety; Aripiprazole; Behavior, Animal; Benzodiazepines; Catalepsy; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Indoles; Ketanserin; Male; Mice; Mice, Inbred ICR; Olanzapine; Piperazines; Piperidines; Postural Balance; Psychomotor Performance; Pyridines; Quinolones; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists | 2008 |
Effects of chronic citalopram treatment on 5-HT1A and 5-HT2A receptors in group- and isolation-housed mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents; Autoradiography; Brain; Brain Chemistry; Citalopram; Data Interpretation, Statistical; Ketanserin; Male; Mice; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Social Environment; Social Isolation | 2008 |
Serotonin 5-HT(2) and 5-HT(1A)-like receptors differentially modulate aggressive behaviors in Drosophila melanogaster.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Amphetamines; Analysis of Variance; Animals; Drosophila melanogaster; Drosophila Proteins; Drug Interactions; Female; Gene Expression; Ketanserin; Male; Membrane Glycoproteins; Motor Activity; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Receptors, Serotonin, 5-HT2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior | 2009 |
Serotonergic mechanisms of the median raphe nucleus-dorsal hippocampus in conditioned fear: Output circuit involves the prefrontal cortex and amygdala.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Conditioning, Classical; Electroshock; Fear; Hippocampus; Ketanserin; Male; Neural Pathways; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Hydroxyindoleacetic Acid; Hypercapnia; Idazoxan; Ketanserin; Locus Coeruleus; Male; Microinjections; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Respiration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Binding Sites; Citalopram; Female; Follow-Up Studies; Hippocampus; Humans; Ketanserin; Longitudinal Studies; Male; Prospective Studies; Protein Binding; Receptor, Serotonin, 5-HT1A | 2011 |
Neuron density and serotonin receptor binding in prefrontal cortex in suicide.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Autoradiography; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Imipramine; Ketanserin; Male; Middle Aged; Neurons; Postmortem Changes; Prefrontal Cortex; Protein Binding; Receptors, Serotonin; Serotonin Agents; Suicide; Tritium; Up-Regulation; Young Adult | 2012 |
Activation of 5-HT(2C) receptors in the dorsal periaqueductal gray increases antinociception in mice exposed to the elevated plus-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Maze Learning; Mice; Microinjections; Nociception; Periaqueductal Gray; Piperazines; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists | 2012 |
Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Stem; Hypercapnia; Ketanserin; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Respiratory Mechanics; Serotonergic Neurons; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2013 |
Distinct effect of 5-HT1A and 5-HT2A receptors in the medial nucleus of the amygdala on tonic immobility behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Corticomedial Nuclear Complex; Fear; Guinea Pigs; Immobility Response, Tonic; Ketanserin; Male; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2016 |
Serotonin antagonists fail to alter MDMA self-administration in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug-Seeking Behavior; Extinction, Psychological; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists | 2016 |
Serotonin modifies the spontaneous spiking activity of gracile nucleus neurons in rats: role of 5-HT1A and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Iontophoresis; Ketanserin; Male; Medulla Oblongata; Neurons; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2016 |
Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear Complex; Fluoxetine; Ketanserin; Male; Rats; Rats, Wistar; Serotonin | 2023 |