ketanserin has been researched along with 1-(3-chlorophenyl)piperazine in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (15.79) | 18.7374 |
| 1990's | 16 (42.11) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 8 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glennon, RA | 2 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Berardi, F; Caroli, A; Colabufo, NA; Contino, M; De Giorgio, P; Di Pilato, P; Hedlund, PB; Lacivita, E; Leopoldo, M; Niso, M; Patarnello, D; Perrone, R; Stroth, N; Svenningsson, P | 1 |
| Cho, H; Cho, YS; Choi, GD; Choi, K; Im, HY; Jang, H; Kim, CH; Kim, YJ; Ko, M; Kwon, OS; Lee, J; Pae, AN; Park, WK; Seo, YW; Tae, J; Yang, HY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Pan, JT; Tai, MH | 1 |
| Broekkamp, CL; Jenck, F; Van Delft, AM | 1 |
| Dyer, DC; Zhang, LB | 1 |
| Cook, LL; Reiter, LW; Sheets, LP | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Barrett, JE; Brady, LS | 1 |
| Clineschmidt, BV; Pettibone, DJ; Reiss, DR; Robinson, JL | 1 |
| Curzon, G; Dourish, CT; Kennett, GA | 1 |
| Bielecka, Z; Bojarski, AJ; Boksa, J; Maćkowiak, M; Mokrosz, JL | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Aulakh, CS; Hulihan-Giblin, BA; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Takeshita, N; Yamaguchi, I | 1 |
| Fiorella, D; Helsley, S; Rabin, RA; Winter, JC | 1 |
| Carey, JE; Chen, C; Elliott, JM; Flanigan, TP; Kumar, C; McDonald, B; Newberry, NR; Newton, RA; Phipps, SL | 1 |
| Abraini, JH; Kriem, B; Rostain, JC | 1 |
| Kennaway, DJ; Moyer, RW | 1 |
| Li, XF; Lovren, F; Lytton, J; Triggle, C | 1 |
| Sugimoto, Y; Yamada, J | 1 |
| Bercovici, E; Cortez, MA; Snead, OC | 1 |
| Canto-de-Souza, A; Nunes-de-Souza, RL; Nunes-de-Souza, V; Rodgers, RJ | 1 |
| Ebiko, M; Ise, SN; Kimura, Y; Mizoguchi, H; Sakurada, S; Watanabe, C; Yonezawa, A; Yoshizumi, M | 1 |
| Fedotova, YO; Ordyan, NE | 1 |
| Fedotova, IuO | 1 |
| Fedotova, IuO; Ordian, NE; Pivina, SG | 1 |
| Baptista, D; Canto-de-Souza, A; Nunes-de-Souza, RL | 1 |
| Fedotova, IuO; Frolova, HO; Ordian, NE; Soboliev, VI | 1 |
2 review(s) available for ketanserin and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
36 other study(ies) available for ketanserin and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action.
Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1999 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
Topics: Animals; Guinea Pigs; HeLa Cells; Humans; Ileum; Ligands; Models, Molecular; Molecular Weight; Piperazine; Piperazines; Protein Conformation; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Substrate Specificity | 2012 |
Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.
Topics: Animals; Anti-Obesity Agents; Area Under Curve; Azepines; Binding, Competitive; Dose-Response Relationship, Drug; Eating; HEK293 Cells; Humans; Ligands; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Chemical; Molecular Structure; Obesity; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Agents; Weight Gain | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of ketanserin on DOI-, MCPP- and TRH-induced prolactin secretion in estrogen-treated rats.
Topics: Amphetamines; Animals; Dopamine Antagonists; Drug Synergism; Estrogens; Female; Ketanserin; Piperazines; Prolactin; Rats; Rats, Inbred Strains; Serotonin Antagonists; Sulpiride; Thyrotropin-Releasing Hormone; Time Factors | 1992 |
5-HT1C receptors in the serotonergic control of periaqueductal gray induced aversion in rats.
Topics: Amphetamines; Animals; Cyproheptadine; Indoles; Ketanserin; Male; Periaqueductal Gray; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement, Psychology; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
Characterization of serotonergic receptors mediating contraction of ovine umbilical artery.
Topics: Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Female; In Vitro Techniques; Ketanserin; Piperazines; Pregnancy; Receptors, Serotonin; Serotonin; Sheep; Umbilical Arteries; Vasoconstriction | 1990 |
Serotonergic modulation of the acoustic startle response in rats during preweaning development.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Age Factors; Animals; Animals, Suckling; Brain Chemistry; Cyproheptadine; Dopamine; Dose-Response Relationship, Drug; Female; Fenclonine; Ketanserin; Male; Methoxydimethyltryptamines; Norepinephrine; Piperazines; Rats; Reflex, Startle; Serotonin; Tetrahydronaphthalenes | 1989 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Effects of serotonin receptor agonists and antagonists on schedule-controlled behavior of squirrel monkeys.
Topics: 5-Hydroxytryptophan; Animals; Cinanserin; Conditioning, Operant; Cyproheptadine; Electroshock; Female; Ketanserin; Male; Metergoline; Methysergide; Piperazines; Piperidines; Pyrazines; Quipazine; Receptors, Serotonin; Saimiri | 1985 |
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperazines; Piperidines; Propranolol; Pyrazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 1985 |
5-HT1B agonists induce anorexia at a postsynaptic site.
Topics: Animals; Appetite Depressants; Haloperidol; Indoles; Ketanserin; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synapses | 1987 |
Structure-activity relationship studies of CNS agents. Part 10(1): 1-Aryl-2-[3-(4-aryl-1-piperazinyl)propyl]-1,4-dihydro-3(2H)-isoquino linones: two modes of the interaction with the 5-HT1A receptor site.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; In Vitro Techniques; Isoquinolines; Ketanserin; Models, Molecular; Piperazines; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship | 1994 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Lack of cross-tolerance for hypophagia induced by DOI versus m-CPP suggests separate mediation by 5-HT2A and 5-HT2C receptors, respectively.
Topics: Amphetamines; Animals; Binding, Competitive; Drug Tolerance; Eating; Ergolines; Frontal Lobe; Injections, Intraperitoneal; Ketanserin; Male; Piperazines; Propane; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Time Factors | 1995 |
Meta-chlorophenylpiperazine attenuates formalin-induced nociceptive responses through 5-HT1/2 receptors in both normal and diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Formaldehyde; Indoles; Ketanserin; Male; Mice; Pain Measurement; Piperazines; Receptors, Serotonin; Serotonin Receptor Agonists; Tropisetron | 1995 |
5-HT2C receptor-mediated phosphoinositide turnover and the stimulus effects of m-chlorophenylpiperazine.
Topics: Animals; Choroid Plexus; Conditioning, Operant; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Ketanserin; Lysergic Acid Diethylamide; Ondansetron; Phosphatidylinositols; Piperazines; Pyrazines; Quipazine; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysiology; Ergolines; Ergotamine; Frontal Lobe; Hallucinogens; Humans; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mescaline; Methoxydimethyltryptamines; Neuroblastoma; Phosphatidylinositols; Piperazines; Quipazine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured | 1996 |
Crucial role of the 5-HT2C receptor, but not of the 5-HT2A receptor, in the down regulation of stimulated dopamine release produced by pressure exposure in freely moving rats.
Topics: Animals; Dopamine; Electrochemistry; Helium; High Pressure Neurological Syndrome; Ketanserin; Male; Nucleus Accumbens; Piperazines; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin | 1998 |
Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms.
Topics: Amphetamines; Animals; Body Temperature; Circadian Rhythm; Ketanserin; Light; Male; Melatonin; Periodicity; Photic Stimulation; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 1998 |
Functional characterization and m-RNA expression of 5-HT receptors mediating contraction in human umbilical artery.
Topics: Humans; Ketanserin; Oxadiazoles; Piperazines; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Sumatriptan; Umbilical Arteries; Vasoconstriction | 1999 |
The 5-HT(2C/2B) receptor agonist, m-chlorophenylpiperazine, increases plasma glucagon levels in rats.
Topics: Adrenal Medulla; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Ketanserin; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |
5-HT2 modulation of AY-9944 induced atypical absence seizures.
Topics: Amphetamines; Animals; Anticholesteremic Agents; Epilepsy, Absence; Ketanserin; Piperazines; Rats; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Serotonin Receptor Agonists; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2007 |
5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice.
Topics: Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Ketanserin; Male; Mesencephalon; Mice; Microinjections; Periaqueductal Gray; Piperazines; Pyridines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2008 |
Ejaculatory response induced by a 5-HT2 receptor agonist m-CPP in rats: differential roles of 5-HT2 receptor subtypes.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Ejaculation; Grooming; Indoles; Injections, Intraperitoneal; Ketanserin; Male; Penile Erection; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2008 |
Blockade of 5-HT2A/2C-type receptors impairs learning in female rats in the course of estrous cycle.
Topics: Analysis of Variance; Animals; Estrous Cycle; Female; Ketanserin; Learning; Maze Learning; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists | 2010 |
[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; Estrogens; Estrous Cycle; Female; Ketanserin; Maze Learning; Piperazines; Rats; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
[Behavioral effects of ketanserine in prenatally stressed female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Female; Ketanserin; Maze Learning; Piperazines; Pregnancy; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2012 |
Activation of 5-HT(2C) receptors in the dorsal periaqueductal gray increases antinociception in mice exposed to the elevated plus-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Maze Learning; Mice; Microinjections; Nociception; Periaqueductal Gray; Piperazines; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists | 2012 |
[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats].
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Depression; Estrogens; Estrus; Female; Injections, Intraperitoneal; Ketanserin; Piperazines; Proestrus; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |