Compounds > kelatorphan
Page last updated: 2024-09-03

kelatorphan and tiopronin

kelatorphan has been researched along with tiopronin in 6 studies

Compound Research Comparison

Studies
(kelatorphan)		Trials
(kelatorphan)		Recent Studies (post-2010)
(kelatorphan)		Studies
(tiopronin)		Trials
(tiopronin)		Recent Studies (post-2010) (tiopronin)
580191232107

Protein Interaction Comparison

ProteinTaxonomykelatorphan (IC50)tiopronin (IC50)
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)1.9

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benoliel, JJ; Berthier, JL; Bourgoin, S; Cesselin, F; Hamon, M; Hirsch, M; Mauborgne, A1
Bourgoin, S; Cesselin, F; Dickenson, AH; Fournié-Zaluski, MC; Hamon, M; Le Bars, D; Roques, BP1
Artaud, F; Bouboutou, R; Bourgoin, S; Cesselin, F; Clot, AM; Fournie-Zaluski, MC; Hamon, M; Le Bars, D; Roques, BP1
Dickenson, AH; Fournie-Zaluski, MC; Roques, BP; Sullivan, AF1
Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G1
Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G1

Other Studies

6 other study(ies) available for kelatorphan and tiopronin

ArticleYear
Enkephalinase is involved in the degradation of endogenous substance P released from slices of rat substantia nigra.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

    Topics: Animals; Captopril; Dipeptides; In Vitro Techniques; Leucine; Male; Metalloendopeptidases; Naloxone; Neprilysin; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Thiorphan; Tiopronin

1987
Increase in met-enkephalin level and antinociceptive effects induced by kelatorphan in the rat spinal cord.
    NIDA research monograph, 1986, Volume: 75

    Topics: Analgesics; Animals; Dipeptides; Enkephalin, Methionine; In Vitro Techniques; Leucine; Neurons; Pain; Rats; Spinal Cord; Thiorphan; Tiopronin

1986
Effects of kelatorphan and other peptidase inhibitors on the in vitro and in vivo release of methionine-enkephalin-like material from the rat spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Animals; Dipeptides; Dose-Response Relationship, Drug; Enkephalin, Methionine; Leucine; Male; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin

1986
Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: Action Potentials; Animals; Dipeptides; Enkephalins; Leucine; Male; Naloxone; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin

1987
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
    European journal of pharmacology, 1985, Nov-05, Volume: 117, Issue:2

    Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1985
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin

1984