kelatorphan has been researched along with morphine in 5 studies
| Studies (kelatorphan) | Trials (kelatorphan) | Recent Studies (post-2010) (kelatorphan) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 58 | 0 | 1 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | kelatorphan (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fournié-Zaluski, MC; Maldonado, R; Roques, BP | 1 |
| Fournié-Zaluski, MC; Noble, F; Peyroux, J; Roques, BP; Schmidt, C | 1 |
| Delay-Goyet, P; Roques, BP; Zajac, JM | 1 |
| Castro-Lopes, JM; Evan, G; Roques, BP; Schadrack, J; Tölle, TR; Zieglgänsberger, W | 1 |
| Crain, SM; Shen, KF | 1 |
5 other study(ies) available for kelatorphan and morphine
| Article | Year |
|---|---|
Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.
Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; Enkephalins; Hydroxamic Acids; Male; Morphine; Morphine Dependence; Naloxone; Neprilysin; Periaqueductal Gray; Phenylalanine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Thiorphan | 1992 |
Analgesic responses elicited by endogenous enkephalins (protected by mixed peptidase inhibitors) in a variety of morphine-sensitive noxious tests.
Topics: Analgesics; Animals; Dipeptides; Dose-Response Relationship, Drug; Enkephalins; Hydroxamic Acids; Male; Mice; Morphine; Naloxone; Phenylalanine; Rats; Rats, Inbred Strains | 1991 |
Effects of repeated treatment with haloperidol on rat striatal neutral endopeptidase, and on mu- and delta-opioid binding sites: comparison with chronic morphine and chronic kelatorphan.
Topics: Animals; Autoradiography; Corpus Striatum; Dipeptides; Haloperidol; Male; Morphine; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1989 |
Effects of Kelatorphan and morphine before and after noxious stimulation on immediate-early gene expression in rat spinal cord neurons.
Topics: Analgesics; Animals; Dipeptides; Dose-Response Relationship, Drug; Gene Expression; Genes, Immediate-Early; Hot Temperature; Immunohistochemistry; Male; Morphine; Naloxone; Neurons; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice.
Topics: Analgesics, Opioid; Animals; Chronic Disease; Dipeptides; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; G(M1) Ganglioside; Hyperalgesia; Male; Mice; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 2007 |