Page last updated: 2024-09-03

kelatorphan and captopril

kelatorphan has been researched along with captopril in 2 studies

Compound Research Comparison

Studies (kelatorphan)	Trials (kelatorphan)	Recent Studies (post-2010) (kelatorphan)	Studies (captopril)	Trials (captopril)	Recent Studies (post-2010) (captopril)
58	0	1	10,320	1,514	890

Protein Interaction Comparison

Protein	Taxonomy	captopril (IC50)
Leukotriene A-4 hydrolase	Homo sapiens (human)	3.6
Angiotensin-converting enzyme	Homo sapiens (human)	0.084
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	0.0173
Succinyl-diaminopimelate desuccinylase	Haemophilus influenzae Rd KW20	3.3
Angiotensin-converting enzyme	Rattus norvegicus (Norway rat)	0.1004
Beta-lactamase	Pseudomonas aeruginosa	5
Angiotensin-converting enzyme 2	Homo sapiens (human)	0.011
Beta-lactamase class B VIM-2	Pseudomonas aeruginosa	3.5

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Devi, LA; Fournié-Zaluski, MC; Gagnidze, K; Orng, SV; Ouimet, T; Poras, H; Roques, BP	1
Benoliel, JJ; Berthier, JL; Bourgoin, S; Cesselin, F; Hamon, M; Hirsch, M; Mauborgne, A	1

Other Studies

2 other study(ies) available for kelatorphan and captopril

Article	Year
Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay. The Journal of biological chemistry, 2010, Nov-05, Volume: 285, Issue:45 Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Endothelins; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Humans; Metalloendopeptidases; Mice; Organ Specificity; Peptide Library; Peptides; Substrate Specificity	2010
Enkephalinase is involved in the degradation of endogenous substance P released from slices of rat substantia nigra. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2 Topics: Animals; Captopril; Dipeptides; In Vitro Techniques; Leucine; Male; Metalloendopeptidases; Naloxone; Neprilysin; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Thiorphan; Tiopronin	1987

Article

Year

Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.

The Journal of biological chemistry, 2010, Nov-05, Volume: 285, Issue:45

Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Endothelins; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Humans; Metalloendopeptidases; Mice; Organ Specificity; Peptide Library; Peptides; Substrate Specificity

2010

Enkephalinase is involved in the degradation of endogenous substance P released from slices of rat substantia nigra.

The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

Topics: Animals; Captopril; Dipeptides; In Vitro Techniques; Leucine; Male; Metalloendopeptidases; Naloxone; Neprilysin; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Protease Inhibitors; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Thiorphan; Tiopronin

1987