Page last updated: 2024-09-03

kb 5492 and cimetidine

kb 5492 has been researched along with cimetidine in 2 studies

Compound Research Comparison

Studies
(kb 5492)
Trials
(kb 5492)
Recent Studies (post-2010)
(kb 5492)
Studies
(cimetidine)
Trials
(cimetidine)
Recent Studies (post-2010) (cimetidine)
8009,4731,687377

Protein Interaction Comparison

ProteinTaxonomykb 5492 (IC50)cimetidine (IC50)
Solute carrier family 22 member 1Mus musculus (house mouse)0.59
Solute carrier family 22 member 2Mus musculus (house mouse)8
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)0.82
Histamine H2 receptorHomo sapiens (human)1.1742
Histamine H2 receptorCavia porcellus (domestic guinea pig)1.02
Potassium-transporting ATPase subunit betaHomo sapiens (human)0.82
Multidrug and toxin extrusion protein 1Homo sapiens (human)3.0333

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morimoto, Y; Oshima, S; Shimohara, K; Sukamoto, T1
Hara, H; Morimoto, Y; Shimohara, K; Sukamoto, T; Tanaka, K1

Other Studies

2 other study(ies) available for kb 5492 and cimetidine

ArticleYear
Effects of the new anti-ulcer agent KB-5492 on experimental gastric mucosal lesions and gastric mucosal defensive factors, as compared to those of teprenone and cimetidine.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:4

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cimetidine; Diterpenes; Gastric Acid; Gastric Mucosa; Hexosamines; Male; Piperazines; Rats; Rats, Inbred Strains; Stomach Ulcer

1991
4-Methoxyphenyl 4-(3,4,5-trimethoxybenzyl)-1-piperazineacetate monofumarate monohydrate (KB-5492), a new anti-ulcer agent with a selective affinity for the sigma receptor, prevents cysteamine-induced duodenal ulcers in rats by a mechanism different from t
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Bicarbonates; Cimetidine; Cysteamine; Duodenal Ulcer; Duodenum; Gastric Acid; Intestinal Secretions; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, sigma

1994