Page last updated: 2024-08-17

kanamycin a and methotrexate

kanamycin a has been researched along with methotrexate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bera, S; Mondal, D1
Huber, JF; van der Wal, S1
Caplan, A; Dekeyser, R; Van Montagu, M1
Frisby, SA; Oliverio, VT; Zager, RF1
Hanazono, H; Imamura, M; Sakamoto, S1

Reviews

2 review(s) available for kanamycin a and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019

Other Studies

11 other study(ies) available for kanamycin a and methotrexate

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Improvement of the efficiency of ion-exchange cellulose columns and their application.
    Journal of chromatography, 1977, May-21, Volume: 135, Issue:2

    Topics: Cellulose; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Kanamycin; Leucovorin; Methotrexate; Novobiocin

1977
Selectable markers for rice transformation.
    Methods in enzymology, 1992, Volume: 216

    Topics: Agrobacterium tumefaciens; Aminobutyrates; Bleomycin; Cinnamates; DNA, Recombinant; Drug Resistance; Electric Stimulation; Gene Expression; Genetic Markers; Gentamicins; Herbicides; Hygromycin B; Kanamycin; Kanamycin Kinase; Methotrexate; Oryza; Phosphotransferases; Protoplasts; Recombinant Proteins; Transfection; Transformation, Genetic

1992
The effects of antibiotics and cancer chemotherapeutic agents on the cellular transport and antitumor activity of methotrexate in L1210 murine leukemia.
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Biological Transport; Bleomycin; Cells, Cultured; Cephalothin; Dose-Response Relationship, Drug; Drug Synergism; Female; Glucocorticoids; Hydroxyurea; Kanamycin; Leukemia L1210; Methotrexate; Mice; Penicillins; Vinblastine; Vinca Alkaloids; Vincristine

1973
Malignant histiocytosis: a case of generalized histiocytosis with infiltration of Langerhans' granule-containing histiocytes.
    Cancer, 1971, Volume: 28, Issue:2

    Topics: Antibiotics, Antineoplastic; Autopsy; Blood Cell Count; Child; Erythrocytes; Female; Histiocytes; Humans; Kanamycin; Leukocyte Count; Liver; Lymph Nodes; Lymphatic Diseases; Methotrexate; Microscopy, Electron; Prednisolone; Skin; Skin Manifestations

1971