Page last updated: 2024-08-17

kanamycin a and bekanamycin

kanamycin a has been researched along with bekanamycin in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (28.79)	18.7374
1990's	13 (19.70)	18.2507
2000's	14 (21.21)	29.6817
2010's	19 (28.79)	24.3611
2020's	1 (1.52)	2.80

Authors

Authors	Studies
Fosso, MY; Garneau-Tsodikova, S; Green, KD; Shrestha, SK	1
Fridman, M; Herzog, IM; Louzoun Zada, S	1
AlFindee, MN; Chang, CT; Subedi, YP; Takemoto, JY	1
Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J	1
Douboyas, J; Grigoriadou-Edipides, A; Papapanagiotou, J; Paradelis, AG; Stathopoulos, G; Triantaphylidis, C	1
Colomba, A; Fundarò, S; Pitruzzella, E	1
Kobayashi, Y; Shitara, T; Tsuchiya, T; Umezawa, S	1
Busson, R; Claes, PJ; Delcourt, J; Mingeot-Leclercq, MP; Mulier, M; Tulkens, PM; Van Schepdael, A; Vanderhaeghe, HJ; Verbist, L	1
Brasseur, R; Busson, R; Claes, PJ; Mingeot-Leclercq, MP; Tulkens, PM; Van Schepdael, A; Vanderhaeghe, HJ	1
Brasseur, R; Busson, R; Claes, PJ; Mingeot-Leclercq, MP; Tulkens, PM; Van Schepdael, A; Vanderhaeghe, HJ; Verbist, L	1
Aburaki, S; Hoshi, H; Kamei, H; Kawaguchi, H; Naito, T; Narita, Y; Yamasaki, T	1
Koeda, T; Yoshida, M	1
Chizhova, NV; Kartseva, VD; Nikolaev, GM; Portnoĭ, IuA	1
Bourret, C; Mallart, A	1
Bartoshevich, IuE; Vikhanskiĭ, IuD; Zhdanovich, IuV	1
Green, C; Yung, MW	1
Hayasaka, S; Shiono, T	1
Beck, H; Eikenberg, P; Sack, K	1
Alvisini, A; Belli, M; Cigala, O	1
Lemeignan, M; Molgo, J; Uchiyama, T	1
Rajan, VS; Thirumoorthy, T	1
Inagaki, M; Majima, Y; Mitsui, H; Miyoshi, Y; Sakakura, Y	1
Inagaki, M; Majima, Y; Miyoshi, Y; Sakakura, Y	1
Cagiano, R; Cuomo, V; Renna, G; Siro-Brigiani, G	1
Sapori, L; Visentin, G	1
Biolchi, S; Germiniani, R; Limido, P; Maltempi, P; Tajana, A	1
Bottino, G; Costa, E; Giannotti, A	1
Cox, JR; Serpersu, EH	1
Hamilton-Miller, JM; Shah, S	1
Castrillon, JL; Hernandez, DA; Morales, MA	1
Carrier, D; Chartrand, N; Matar, W	1
Farca, AM; Maffei, F; Piromalli, G; Re, G	1
Cho, J; Hamasaki, K; Killian, J; Rando, RR	1
Jezowska-Bojczuk, M; Karaczyn, A; Kozłowski, H	1
Brännvall, M; Kirsebom, LA; Mikkelsen, NE; Virtanen, A	1
Chun, SM; Jeong, S; Kwon, M; Yu, J	1
Rando, RR; Ryu, DH	1
Hoogmartens, J; Kaale, E; Roets, E; Van Schepdael, A	1
ITO, T; NISHIO, M; OGAWA, H	1
Tor, Y	1
Chen, CH; Chou, CH; Hung, SC; Kulkarni, SS; Lu, LD; Wong, CH; Wu, CS	1
Chang, CW; Chang, H; Czyryca, PG; Evanson, R; Li, J; Orsak, TW; Wang, J	1
Du, Y; Li, T; Wang, YG; Xia, H	1
Ozen, C; Serpersu, EH	1
Chang, CW; Chang, H; Chen, HN; Czyryca, PG; Li, J; Liu, HH; Tanifum, CT; Wang, J	1
Hanko, VP; Rohrer, JS	1
Hauser, PC; Kubán, P; Law, WS; Li, SF; Yuan, LL; Zhao, JH	1
Barbieri, CM; Kaul, M; Pilch, DS; Srinivasan, AR	1
Birk, AV; Dubovi, EJ; Szeto, HH; Zhang, X	1
Belousoff, MJ; Graham, B; Spiccia, L; Tor, Y	1
Norris, AL; Ozen, C; Serpersu, EH	1
Asensio, JL; Bastida, A; Corzana, F; Gómez, AM; González, C; Jiménez-Osés, G; Revuelta, J; Vacas, T	1
Bensaci, MF; Chang, CW; Evans, CK; Fosso, M; Kawasaki, Y; Shrestha, S; Takemoto, JY; Wang, J	1
Huang, T; Li, D; Li, H; Ni, X; Xia, H; Yang, L	1
Cowan, JA; Patwardhan, A	1
Asensio, JL; Bastida, A; Corzana, F; Gómez-Pinto, I; González, C; Jiménez-Barbero, J; Jiménez-Moreno, E; Revuelta, J; Santana, AG	1
He, HM; Li, C; Liu, FJ; Qiao, RZ; Wang, BW; Zhang, J; Zhang, Y	1
Chen, Y; Fierke, CA; Liu, X	1
Choi, BE; Li, J; Soto, AM; Truitt, AR	1
Asensio, JL; Bastida, A; Cañada, FJ; Corzana, F; Gómez, AM; Gómez-Pinto, I; González, C; Jiménez-Barbero, J; Jiménez-Moreno, E; Jiménez-Osés, G; Montalvillo-Jiménez, L; Santana, AG	1
Eguchi, T; Kudo, F; Tokumitsu, T	1
Borovika, A; Khomutnyk, Y; Lee, J; Nagorny, P	1
Gao, W; Ni, X; Sun, J; Wu, Z; Xia, H	1
Bury, PDS; Dias, MVB; Huang, F; Leadlay, PF; Li, S; Sun, Y	1
Chen, T; Guo, L; Jia, J; Li, C; Qiao, R; Zhang, H; Zhang, S	1
Borowski, T; Guzik, M; Minor, W; Miłaczewska, A; Mrugała, B; Niedzialkowska, E; Porebski, PJ	1

Reviews

3 review(s) available for kanamycin a and bekanamycin

Article	Year
Antifungal amphiphilic kanamycins: new life for an old drug. MedChemComm, 2018, Jun-01, Volume: 9, Issue:6 Topics:	2018
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities. European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles	2019
Targeting RNA with small molecules. Chembiochem : a European journal of chemical biology, 2003, Oct-06, Volume: 4, Issue:10 Topics: Anti-Bacterial Agents; Drug Delivery Systems; Kanamycin; Models, Molecular; RNA; RNA, Catalytic; RNA, Ribosomal; Static Electricity; Structure-Activity Relationship	2003

Trials

1 trial(s) available for kanamycin a and bekanamycin

Article	Year
[Short-term prevention of surgical infections with antibiotics. Preliminary results of a controlled clinical experimentation]. Minerva chirurgica, 1982, Mar-15, Volume: 37, Issue:5 Topics: Ampicillin; Anti-Bacterial Agents; Clinical Trials as Topic; Fosfomycin; Humans; Kanamycin; Respiratory Tract Infections; Surgical Wound Infection; Urinary Tract Infections	1982

Other Studies

62 other study(ies) available for kanamycin a and bekanamycin

Article	Year
Synthesis and Bioactivities of Kanamycin B-Derived Cationic Amphiphiles. Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Bacterial Infections; Cell Line; Cell Survival; Drug Design; Drug Resistance, Microbial; Fungi; Hemolysis; Humans; Kanamycin; Mice; Mycoses; Surface-Active Agents	2015
Effects of 5-O-Ribosylation of Aminoglycosides on Antimicrobial Activity and Selective Perturbation of Bacterial Translation. Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17 Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli Proteins; Framycetin; Gram-Negative Bacteria; Kanamycin; Microbial Sensitivity Tests; Ribose; Structure-Activity Relationship; Trisaccharides	2016
In vitro comparison of kanamycin, kanendomycin, gentamicin, amikacin, sisomicin, and dibekacin against 200 strains of Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:3 Topics: Dibekacin; Drug Resistance, Microbial; Gentamicins; Kanamycin; Pseudomonas aeruginosa	1978
[Treatment of enteritis with kanendomycin]. Minerva pediatrica, 1978, Jul-15, Volume: 30, Issue:13 Topics: Anti-Bacterial Agents; Child; Child, Preschool; Enteritis; Enterobacteriaceae Infections; Female; Humans; Infant; Kanamycin; Male	1978
Synthesis of 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of kanamycin B and its analogs. Study on structure-toxicity relationships. Carbohydrate research, 1992, Aug-03, Volume: 232, Issue:2 Topics: Carbohydrate Sequence; Kanamycin; Molecular Sequence Data; Structure-Activity Relationship	1992
New derivatives of kanamycin B obtained by modifications and substitutions in position 6". 1. Synthesis and microbiological evaluation. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship	1991
New derivatives of kanamycin B obtained by modifications and substitutions in position 6''. 2. In vitro and computer-aided toxicological evaluation with respect to interactions with phosphatidylinositol. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Computer Graphics; Indicators and Reagents; Kanamycin; Lysosomes; Models, Molecular; Molecular Conformation; Molecular Structure; Phospholipases A; Phospholipases A1; Structure-Activity Relationship	1991
New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Gram-Positive Bacteria; Indicators and Reagents; Kanamycin; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship	1991
Synthesis and biological activity of 1-N-[4-(substituted)amidino and guanidino-2-hydroxybutyryl]kanamycins A and B. The Journal of antibiotics, 1991, Volume: 44, Issue:6 Topics: Animals; Bacteria; Bacterial Infections; Kanamycin; Kidney; Lethal Dose 50; Magnetic Resonance Spectroscopy; Mice; Molecular Structure	1991
Effect of aminoglycoside antibiotics on the electrical stimulation-induced contractile response of the guinea-pig ureter. Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:3 Topics: Animals; Anti-Bacterial Agents; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kanamycin; Muscle Contraction; Muscle, Smooth; Ribostamycin; Ureter	1989
[Determination of the kanamycin B content of kanamycin preparations by column chromatography]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:8 Topics: Anion Exchange Resins; Chromatography, Ion Exchange; Drug Contamination; Electron Spin Resonance Spectroscopy; Kanamycin; Resins, Synthetic	1987
Depression of calcium current at mouse motor nerve endings by polycationic antibiotics. Brain research, 1989, Jan-30, Volume: 478, Issue:2 Topics: Animals; Anti-Bacterial Agents; Calcium; Electric Stimulation; In Vitro Techniques; Kanamycin; Membrane Potentials; Mice; Neuromuscular Junction; Tetraethylammonium Compounds	1989
[Identification of idiotrophs for 3'-deoxykanamycin B synthesis in Streptomyces tenebrarius (Higgens a. Kastner)]. Genetika, 1987, Volume: 23, Issue:5 Topics: Bacteriological Techniques; Kanamycin; Mutation; Streptomyces; Tobramycin	1987
Interaction of kanamycin A and kanamycin B with phospholipids. The Journal of antibiotics, 1987, Volume: 40, Issue:6 Topics: Anilino Naphthalenesulfonates; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Kanamycin; Liposomes; Membrane Lipids; Phosphatidylinositols; Phospholipids; Spectrometry, Fluorescence	1987
Aminoglycoside antibiotics and lysosomal enzymes of human tears. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:11 Topics: Acetylglucosaminidase; Acid Phosphatase; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Depression, Chemical; Dibekacin; Erythromycin; Gentamicins; Hexosaminidases; Humans; Kanamycin; Muramidase; Sulbenicillin; Tears; Tobramycin	1985
[Experimental study on renal tolerability of aminoglycosides butirosin and bekanamycin (author's transl)]. Arzneimittel-Forschung, 1980, Volume: 30, Issue:2 Topics: Animals; Anti-Bacterial Agents; Butirosin Sulfate; Enzymes; Female; Kanamycin; Kidney; Kidney Diseases; Proteinuria; Rats; Time Factors; Urea	1980
[Kanendomycin in the topical treatment of proctosigmoiditis]. La Clinica terapeutica, 1984, Oct-31, Volume: 111, Issue:2 Topics: Administration, Topical; Colitis; Humans; Kanamycin; Proctocolitis	1984
Presynaptic effects of bekanamycin at the frog neuromuscular junction. Reversibility by calcium and aminopyridines. European journal of pharmacology, 1981, Jul-10, Volume: 72, Issue:4 Topics: Aminopyridines; Animals; Calcium; Evoked Potentials; In Vitro Techniques; Kanamycin; Motor Endplate; Neuromuscular Junction; Rana esculenta; Synaptic Transmission	1981
Penicillinase-producing Neisseria gonorrhoeae in Great Britain, 1977-81. British medical journal (Clinical research ed.), 1982, Nov-27, Volume: 285, Issue:6354 Topics: Cefotaxime; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Kanamycin; Male; Neisseria gonorrhoeae; Ophthalmia Neonatorum; Penicillinase	1982
Absorption of various drugs through the rabbit's respiratory mucosa in vitro. Archives of oto-rhino-laryngology, 1983, Volume: 238, Issue:1 Topics: Absorption; Animals; Cefazolin; Doxycycline; Immunoenzyme Techniques; Immunoglobulin G; Kanamycin; Mucous Membrane; Nasal Mucosa; Penicillin G; Pharmaceutical Preparations; Prednisolone; Rabbits; Respiratory System	1983
[Absorption of drugs from rabbit nasal mucosa in vivo]. Nihon Jibiinkoka Gakkai kaiho, 1984, Volume: 87, Issue:2 Topics: Absorption; Aerosols; Animals; Guinea Pigs; Immunoenzyme Techniques; Immunoglobulin G; Kanamycin; Models, Biological; Nasal Mucosa; Rabbits	1984
Effects of two new aminoglycoside antibiotics on the rat sciatic nerve-gastrocnemius muscle preparation. Arzneimittel-Forschung, 1983, Volume: 33, Issue:10 Topics: Animals; Calcium; Electric Stimulation; In Vitro Techniques; Kanamycin; Male; Neostigmine; Neuromuscular Blocking Agents; Rats; Rats, Inbred Strains; Sisomicin; Tobramycin	1983
[Personal experience with kanendomycin in the treatment of various infectious bronchopulmonary diseases]. La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1 Topics: Adolescent; Adult; Aged; Bacterial Infections; Bronchiectasis; Bronchitis; Bronchopneumonia; Female; Humans; Kanamycin; Male; Middle Aged; Respiratory Tract Infections	1983
[The use of kanendomycin in aerosol administration in chronic obstructive bronchopneumopathy]. La Clinica terapeutica, 1981, Oct-31, Volume: 99, Issue:2 Topics: Adolescent; Adult; Aerosols; Aged; Female; Humans; Kanamycin; Lung Diseases, Obstructive; Male; Middle Aged	1981
The complete 1H NMR assignments of aminoglycoside antibiotics and conformational studies of butirosin A through the use of 2D NMR spectroscopy. Carbohydrate research, 1995, Jul-10, Volume: 271, Issue:1 Topics: Butirosin Sulfate; Carbohydrate Conformation; Carbohydrate Sequence; Hydrogen-Ion Concentration; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure	1995
Activity of the semi-synthetic kanamycin B derivative, arbekacin against methicillin-resistant Staphylococcus aureus. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:6 Topics: Aminoglycosides; Anti-Bacterial Agents; Dibekacin; Kanamycin; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus	1995
Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells. Archives of medical research, 1993,Winter, Volume: 24, Issue:4 Topics: Action Potentials; Animals; Anura; Calcium; Dibekacin; Heart Conduction System; In Vitro Techniques; Kanamycin; Verapamil	1993
Comparison of the effects of amikacin and kanamycins A and B on dimyristoylphosphatidylglycerol bilayers. An infrared spectroscopic investigation. Biochemical pharmacology, 1997, Feb-07, Volume: 53, Issue:3 Topics: Amikacin; Anti-Bacterial Agents; Kanamycin; Lipid Bilayers; Membrane Fluidity; Phosphatidylglycerols; Spectroscopy, Fourier Transform Infrared	1997
Potentiating effect of EDTA-Tris on the activity of antibiotics against resistant bacteria associated with otitis, dermatitis and cystitis. The Journal of small animal practice, 1997, Volume: 38, Issue:6 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Buffers; Cephaloridine; Cephalosporins; Cystitis; Dermatitis; Dog Diseases; Dogs; Drug Synergism; Edetic Acid; Enrofloxacin; Escherichia coli Infections; Female; Fluoroquinolones; Kanamycin; Male; Otitis; Proteus Infections; Proteus mirabilis; Pseudomonas Infections; Quinolones; Staphylococcal Infections; Time Factors; Tromethamine	1997
Minimal RNA constructs that specifically bind aminoglycoside antibiotics with high affinities. Biochemistry, 1998, Jan-13, Volume: 37, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Gentamicins; Kanamycin; Neomycin; Nucleic Acid Conformation; RNA; Structure-Activity Relationship; Tobramycin	1998
Copper(II) binding to tobramycin: potentiometric and spectroscopic studies. Carbohydrate research, 1998, Dec-15, Volume: 313, Issue:3-4 Topics: Anti-Bacterial Agents; Carbohydrate Conformation; Chelating Agents; Circular Dichroism; Copper; Electron Spin Resonance Spectroscopy; Humans; Kanamycin; Potentiometry; Protons; Tobramycin; Ultraviolet Rays	1998
Inhibition of RNase P RNA cleavage by aminoglycosides. Proceedings of the National Academy of Sciences of the United States of America, 1999, May-25, Volume: 96, Issue:11 Topics: Anti-Bacterial Agents; Base Sequence; Binding, Competitive; Endoribonucleases; Escherichia coli; Escherichia coli Proteins; Framycetin; Kanamycin; Kinetics; Lead; Magnesium; Models, Molecular; Molecular Sequence Data; Mycoplasma; Nucleic Acid Conformation; Paromomycin; Recombinant Proteins; Ribonuclease P; RNA; RNA, Catalytic; RNA, Ribosomal, 16S; Substrate Specificity; Transcription, Genetic	1999
In vitro selection of RNA against kanamycin B. Molecules and cells, 2001, Jun-30, Volume: 11, Issue:3 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Drug Design; In Vitro Techniques; Kanamycin; Molecular Sequence Data; Nucleic Acid Conformation; RNA	2001
Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10 Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Fluorescence Polarization; Framycetin; Humans; Kanamycin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Paromomycin; Rhodamines; RNA, Ribosomal; RNA, Ribosomal, 16S; RNA, Ribosomal, 18S; Structure-Activity Relationship; Tobramycin	2001
Development and validation of capillary electrophoresis method for tobramycin with precapillary derivatization and UV detection. Electrophoresis, 2002, Volume: 23, Issue:11 Topics: Acetonitriles; Anti-Bacterial Agents; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Kanamycin; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Temperature; Tobramycin	2002
THE STRUCTURE OF KANAMYCIN B. The Journal of antibiotics, 1964, Volume: 17 Topics: Kanamycin	1964
Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues. Organic letters, 2004, Feb-19, Volume: 6, Issue:4 Topics: Aminoglycosides; Catalysis; Glycosylation; Indicators and Reagents; Kanamycin; Molecular Structure; Stereoisomerism	2004
Application of glycodiversification: expedient synthesis and antibacterial evaluation of a library of kanamycin B analogues. Organic letters, 2004, Apr-29, Volume: 6, Issue:9 Topics: Anti-Bacterial Agents; Carbohydrate Conformation; Carbohydrate Sequence; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Microbial Sensitivity Tests; Molecular Sequence Data; RNA, Ribosomal, 16S; Staphylococcus aureus; Structure-Activity Relationship	2004
Identification and functional analysis of dTDP-glucose-4,6-dehydratase gene and its linked gene cluster in an aminoglycoside antibiotics producer of Streptomyces tenebrarius H6. Current microbiology, 2004, Volume: 49, Issue:2 Topics: Amino Acid Sequence; Chromosomes, Bacterial; Clostridium; DNA, Bacterial; Gene Deletion; Gene Order; Genes, Bacterial; Glycosyltransferases; Hydro-Lyases; Kanamycin; Mannosyltransferases; Molecular Sequence Data; Multigene Family; Mutagenesis, Insertional; Nebramycin; Open Reading Frames; Pseudomonas putida; Rhamnose; Sequence Analysis, DNA; Sequence Homology; Streptomyces; Thymine Nucleotides; Tobramycin; Xanthomonas	2004
Thermodynamics of aminoglycoside binding to aminoglycoside-3'-phosphotransferase IIIa studied by isothermal titration calorimetry. Biochemistry, 2004, Nov-23, Volume: 43, Issue:46 Topics: Adenosine Triphosphate; Amines; Aminoglycosides; Binding Sites; Calcium; Calorimetry; Entropy; Hexosamines; Hydroxides; Kanamycin; Kanamycin Kinase; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Substrate Specificity; Thermodynamics	2004
Glycodiversification for the optimization of the kanamycin class aminoglycosides. Journal of medicinal chemistry, 2005, Oct-06, Volume: 48, Issue:20 Topics: Anti-Bacterial Agents; Carbohydrate Sequence; Drug Resistance, Bacterial; Escherichia coli; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; RNA; Staphylococcus aureus; Structure-Activity Relationship	2005
Determination of tobramycin and impurities using high-performance anion exchange chromatography with integrated pulsed amperometric detection. Journal of pharmaceutical and biomedical analysis, 2006, Mar-03, Volume: 40, Issue:4 Topics: Anion Exchange Resins; Anti-Bacterial Agents; Chromatography, Ion Exchange; Electrochemistry; Electrodes; Gold; Kanamycin; Reproducibility of Results; Technology, Pharmaceutical; Temperature; Tobramycin	2006
Determination of tobramycin in human serum by capillary electrophoresis with contactless conductivity detection. Electrophoresis, 2006, Volume: 27, Issue:10 Topics: Acetic Acid; Anti-Bacterial Agents; Blood Chemical Analysis; Electric Conductivity; Electrophoresis, Capillary; Humans; Kanamycin; Sensitivity and Specificity; Tobramycin	2006
Molecular determinants of antibiotic recognition and resistance by aminoglycoside phosphotransferase (3')-IIIa: a calorimetric and mutational analysis. Journal of molecular biology, 2007, May-25, Volume: 369, Issue:1 Topics: Amino Acids; Anti-Bacterial Agents; Calorimetry; Catalysis; Circular Dichroism; Coenzymes; DNA Mutational Analysis; Drug Resistance, Bacterial; Escherichia coli; Hydrogen-Ion Concentration; Kanamycin; Kanamycin Kinase; Kanamycin Resistance; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mutation; Neomycin; Protein Binding; Protons; Structure-Activity Relationship; Temperature; Thermodynamics; Titrimetry	2007
Antiviral activity of geneticin against bovine viral diarrhoea virus. Antiviral chemistry & chemotherapy, 2008, Volume: 19, Issue:1 Topics: Animals; Antiviral Agents; Bovine Virus Diarrhea-Mucosal Disease; Cattle; Cell Survival; Cells, Cultured; Diarrhea Virus 1, Bovine Viral; Gentamicins; Interferons; Kanamycin; Kidney; Neutralization Tests; Peptide Hydrolases; Reverse Transcriptase Polymerase Chain Reaction; RNA Helicases; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication	2008
Cleavage of RNA oligonucleotides by aminoglycosides. Organic & biomolecular chemistry, 2009, Jan-07, Volume: 7, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Esterification; Framycetin; HIV Long Terminal Repeat; HIV-1; Hydrogen-Ion Concentration; Kanamycin; Kinetics; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Ribosomes; RNA	2009
Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme. Biochemistry, 2010, May-18, Volume: 49, Issue:19 Topics: Acetyltransferases; Anti-Bacterial Agents; Binding Sites; Kanamycin; Kinetics; Paromomycin; Ribostamycin; Substrate Specificity; Thermodynamics; Tobramycin	2010
Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: implications for drug design. Journal of the American Chemical Society, 2010, Sep-01, Volume: 132, Issue:34 Topics: Aminoglycosides; Anti-Bacterial Agents; Crystallography, X-Ray; Drug Design; Kanamycin; Models, Molecular; Molecular Conformation; Ribostamycin; Stereoisomerism	2010
Antibacterial to antifungal conversion of neamine aminoglycosides through alkyl modification. Strategy for reviving old drugs into agrofungicides. The Journal of antibiotics, 2010, Volume: 63, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Cell Membrane; Crops, Agricultural; Fungicides, Industrial; Fusarium; Kanamycin; Plant Diseases; Plant Leaves; Trisaccharides; Triticum	2010
Construction of kanamycin B overproducing strain by genetic engineering of Streptomyces tenebrarius. Applied microbiology and biotechnology, 2011, Volume: 89, Issue:3 Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Gene Deletion; Genes, Bacterial; Genetic Engineering; Kanamycin; Oxidoreductases; Streptomyces	2011
Influence of charge and structure on the coordination chemistry of copper aminoglycosides. Dalton transactions (Cambridge, England : 2003), 2011, Feb-28, Volume: 40, Issue:8 Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Copper; Framycetin; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Structure; Paromomycin; Spectrophotometry, Ultraviolet; Static Electricity; Tobramycin	2011
Chemical interrogation of drug/RNA complexes: from chemical reactivity to drug design. Angewandte Chemie (International ed. in English), 2013, Mar-11, Volume: 52, Issue:11 Topics: Amination; Aminoglycosides; Chemistry, Pharmaceutical; Combinatorial Chemistry Techniques; Drug Design; Formaldehyde; Kanamycin; Models, Molecular; RNA	2013
HPLC-ELSD determination of kanamycin B in the presence of kanamycin A in fermentation broth. Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3 Topics: Calibration; Chemical Fractionation; Chromatography, High Pressure Liquid; Culture Media; Drug Stability; Fermentation; Kanamycin; Light; Reproducibility of Results; Scattering, Radiation; Sensitivity and Specificity; Temperature	2015
A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P. Nucleic acids research, 2014, Nov-10, Volume: 42, Issue:20 Topics: Anti-Bacterial Agents; Bacillus subtilis; Enzyme Inhibitors; Fluorescence Polarization; Framycetin; High-Throughput Screening Assays; Kanamycin; Ribonuclease P; RNA Cleavage; RNA, Transfer	2014
Effect of Mutations on the Binding of Kanamycin-B to RNA Hairpins Derived from the Mycobacterium tuberculosis Ribosomal A-Site. Biochemistry, 2015, Dec-29, Volume: 54, Issue:51 Topics: Anti-Bacterial Agents; Circular Dichroism; Kanamycin; Molecular Structure; Mutation; Mycobacterium tuberculosis; Nucleic Acid Conformation; Ribosomes; RNA, Bacterial; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	2015
Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders. Journal of the American Chemical Society, 2016, 05-25, Volume: 138, Issue:20 Topics: Combinatorial Chemistry Techniques; Drug Discovery; Kanamycin; Microdialysis; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Quantum Theory; Small Molecule Libraries	2016
Substrate specificity of radical S-adenosyl-l-methionine dehydratase AprD4 and its partner reductase AprD3 in the C3'-deoxygenation of aminoglycoside antibiotics. The Journal of antibiotics, 2017, Volume: 70, Issue:4 Topics: Actinobacteria; Aminoglycosides; Anti-Bacterial Agents; Hydro-Lyases; Kanamycin; NADP; Nebramycin; Substrate Specificity	2017
Chiral phosphoric acid-catalyzed desymmetrizative glycosylation of 2-deoxystreptamine and its application to aminoglycoside synthesis. Chemical communications (Cambridge, England), 2017, Aug-08, Volume: 53, Issue:64 Topics: Aminoglycosides; Catalysis; Framycetin; Glycosylation; Hexosamines; Kanamycin; Phosphoric Acids; Stereoisomerism	2017
Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering. PloS one, 2017, Volume: 12, Issue:7 Topics: Biosynthetic Pathways; Cell Proliferation; Genotype; Kanamycin; Metabolic Engineering; Metabolome; Metabolomics; Multigene Family; Real-Time Polymerase Chain Reaction; Recombination, Genetic; Streptomyces; Transcription, Genetic	2017
Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS chemical biology, 2017, 11-17, Volume: 12, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Crystallography, X-Ray; Gentamicins; Kanamycin; Methyltransferases; Micromonospora; Models, Molecular; Protein Conformation; Substrate Specificity; Tobramycin	2017
Establishment of a highly efficient conjugation protocol for Streptomyces kanamyceticus ATCC12853. MicrobiologyOpen, 2019, Volume: 8, Issue:6 Topics: Anti-Bacterial Agents; Conjugation, Genetic; Escherichia coli; Fermentation; Gene Transfer Techniques; Kanamycin; Plasmids; Streptomyces	2019
A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. The FEBS journal, 2021, Volume: 288, Issue:4 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Biocatalysis; Carbohydrate Sequence; Catalytic Domain; Crystallography, X-Ray; Dioxygenases; Kanamycin; Kinetics; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Protein Conformation; Streptomyces; Substrate Specificity	2021