kainic acid has been researched along with phenobarbital in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (35.14) | 18.7374 |
| 1990's | 9 (24.32) | 18.2507 |
| 2000's | 8 (21.62) | 29.6817 |
| 2010's | 5 (13.51) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Cavazos, J; Golarai, G; Sutula, T | 1 |
| Daniels, S; Inman, N; Price, DJ; Shelton, CJ; Smith, EB; Zhao, DM | 1 |
| Frandsen, A; Quistorff, B; Schousboe, A | 1 |
| Kubová, H; Mares, P; Roztocilová, L; Velísek, L | 1 |
| Ackermann, RF; Feldblum, S | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV | 1 |
| Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Okazaki, MM | 1 |
| Choi, DW; Koh, JY | 1 |
| De Bonnel, G; De Montigny, C | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 1 |
| Fuller, TA; Olney, JW | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Gerard, D; Potashner, SJ | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L | 1 |
| Bernard, PS; Liebman, JM; Pastor, G; Saelens, JK | 1 |
| Costa, E; Gillin, JC; Hong, JS; Wood, PL; Yang, HY | 1 |
| Chronopoulos, A; Gatt, A; Holmes, GL; Hyde, P; Liu, Z; Mikati, MA; Stafstrom, CE; Thurber, S; Werner, S | 1 |
| Kiuchi, Y; Kuroiwa, Y; Numazawa, S; Oguchi, K; Tanaka, S; Yoshida, T | 1 |
| Bolanos, AR; Helmers, SL; Holmes, GL; Hori, A; Mikati, M; Sarkisian, M; Stafstrom, CE; Tandon, P; Yang, Y | 1 |
| Gelowitz, DL; Paterson, IA | 1 |
| Andoh, T; Furuya, R; Hattori, S; Ito, H; Kamiya, Y; Okumura, F; Sasaki, T; Watanabe, I | 1 |
| Czuczwar, SJ; Haberek, G; Kleinrok, Z; Matyska, J; Pilip, S; Tomczyk, T; Turski, WA; Urbanska, EM | 1 |
| Mellanby, J; Milward, AJ | 1 |
| Burgos, JS; Frizzo, ME; Lara, DR; Ramírez, G; Schmidt, AP; Souza, DO | 1 |
| Brown-Croyts, LM; Caton, PW; McPherson, SL; Radecki, DT | 1 |
| Abu Rialy, S; Farhat, F; Francis, E; Geha, G; Kurdit, RM; Lteif, L; Maraashli, W; Mikati, MA; Rahmeh, AA | 1 |
| Kato, N; Kayama, T; Sato, S; Yokoyama, H; Yoshimura, T | 1 |
| Benke, TA; Brumback, AC; Delpire, E; Dzhala, VI; Jensen, FE; Mathews, GC; Sdrulla, DA; Staley, KJ; Talos, DM | 1 |
| Liu, X; Yang, H; Yang, J; Yang, Z | 1 |
| Brooks-Kayal, AR; Cooper, EC; Keating, JG; Lapides, DA; Raol, YH | 1 |
| Brandt, C; Löscher, W; Rattka, M | 1 |
| Balderas, G; Diaz-Ruiz, A; Galván-Arzate, S; Manjarrez, J; Mendez-Armenta, M; Nava-Ruiz, C; Ríos, C; Santander, I | 1 |
| Brandt, C; Erker, T; Löscher, W; Töllner, K | 1 |
| Bankstahl, M; Klein, S; Löscher, W | 1 |
| Boylan, GB; Henshall, DC; Jimenez-Mateos, EM; Madden, SF; Molloy, EJ; Quinlan, SMM; Rodriguez-Alvarez, N | 1 |
| Auer, T; Erker, T; Schreppel, P; Schwarzer, C | 1 |
| Barker-Haliski, M; Knox, K; Koneval, Z; Metcalf, C; White, HS; Wilcox, KS; Zierath, D | 1 |
37 other study(ies) available for kainic acid and phenobarbital
| Article | Year |
|---|---|
Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital.
Topics: Animals; Hippocampus; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Nerve Degeneration; Nerve Fibers; Phenobarbital; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Time Factors | 1992 |
Effects of general anesthetics and pressure on mammalian excitatory receptors expressed in Xenopus oocytes.
Topics: Animals; Brain; Female; Kainic Acid; Male; Membrane Potentials; Microinjections; Oocytes; Phenobarbital; Poly A; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; RNA, Messenger; Spinal Cord; Xenopus laevis | 1991 |
Phenobarbital protects cerebral cortex neurones against toxicity induced by kainate but not by other excitatory amino acids.
Topics: Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Kainic Acid; Mice; Neurotoxins; Phenobarbital | 1990 |
Effects of carbamazepine and phenobarbital on kainic acid-induced model of psychomotor seizures during ontogenesis in the rat.
Topics: Aging; Animals; Carbamazepine; Dose-Response Relationship, Drug; Kainic Acid; Male; Phenobarbital; Rats; Rats, Inbred Strains; Seizures | 1989 |
Increased susceptibility to hippocampal and amygdala kindling following intrahippocampal kainic acid.
Topics: Amygdala; Animals; Diazepam; Electric Stimulation; Electroencephalography; Hippocampus; Kainic Acid; Kindling, Neurologic; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
Efficacy of baclofen and phenobarbital against the kainic acid limbic seizure-brain damage syndrome.
Topics: Animals; Baclofen; Behavior, Animal; Brain; Electroencephalography; Injections, Intraventricular; Kainic Acid; Limbic System; Male; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Time Factors | 1986 |
Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Phenobarbital; Rats; Seizures; Time Factors | 1986 |
Effect of anticonvulsant drugs on glutamate neurotoxicity in cortical cell culture.
Topics: Animals; Anticonvulsants; Brain Diseases; Cells, Cultured; Cerebral Cortex; Diazepam; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Mice; Phenobarbital; Phenytoin | 1987 |
Benzodiazepine selectively antagonize kainate-induced activation in the rat hippocampus.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Benzodiazepinones; Chlorpromazine; Diazepam; Flumazenil; Glutamates; Hippocampus; Injections, Intravenous; Iontophoresis; Kainic Acid; Lorazepam; Male; Phenobarbital; Pyramidal Tracts; Pyrrolidines; Rats; Rats, Inbred Strains | 1983 |
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid | 1981 |
Only certain anticonvulsants protect against kainate neurotoxicity.
Topics: Animals; Anticonvulsants; Diazepam; Kainic Acid; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1981 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Kainate-enhanced release of D-[3H]aspartate from cerebral cortex and striatum: reversal by baclofen and pentobarbital.
Topics: Animals; Aspartic Acid; Baclofen; Biological Transport; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Guinea Pigs; Kainic Acid; Kinetics; Phenobarbital; Pyrrolidines; Sodium; Tritium | 1983 |
Anticonvulsant action of phenobarbital, diazepam, carbamazepine, and diphenylhydantoin in the electroshock test in mice after lesion of hippocampal pyramidal cells with intracerebroventricular kainic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Electroshock; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Seizures | 1982 |
Antagonism of intrastriatal and intravenous kainic acid by 1-nuciferine: comparison with various anticonvulsants and GABAmimetics.
Topics: Animals; Aporphines; Baclofen; Behavior, Animal; Choline O-Acetyltransferase; Corpus Striatum; Diazepam; Excitatory Amino Acid Antagonists; Haloperidol; Injections; Kainic Acid; Male; Phenobarbital; Pyrrolidines; Rats; Seizures | 1980 |
Changes of hippocampal Met-enkephalin content after recurrent motor seizures.
Topics: Animals; Endorphins; Enkephalins; Functional Laterality; Hippocampus; Kainic Acid; Male; Phenobarbital; Pyrrolidines; Rats; Seizures; Time Factors | 1980 |
Phenobarbital modifies seizure-related brain injury in the developing brain.
Topics: Aging; Analysis of Variance; Animals; Brain Diseases; Kainic Acid; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Status Epilepticus | 1994 |
Changes in glutamate receptors, c-fos mRNA expression and activator protein-1 (AP-1) DNA binding activity in the brain of phenobarbital-dependent and -withdrawn rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Brain; Dizocilpine Maleate; DNA-Binding Proteins; GABA Modulators; Histocytochemistry; In Situ Hybridization; Kainic Acid; Male; Phenobarbital; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Receptors, Glutamate; RNA, Messenger; Substance Withdrawal Syndrome; Substance-Related Disorders; Transcription Factor AP-1 | 1997 |
Comparison of valproate and phenobarbital treatment after status epilepticus in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Maze Learning; Phenobarbital; Rats; Rats, Sprague-Dawley; Status Epilepticus; Stress, Physiological; Valproic Acid | 1998 |
Neuronal sparing and behavioral effects of the antiapoptotic drug, (-)deprenyl, following kainic acid administration.
Topics: Animals; Apoptosis; Drug Interactions; Excitatory Amino Acid Agonists; Hypnotics and Sedatives; Kainic Acid; Male; Motor Activity; Neurons; Neuroprotective Agents; Phenobarbital; Rats; Rats, Wistar; Selegiline | 1999 |
Comparison of the effects of convulsant and depressant barbiturate stereoisomers on AMPA-type glutamate receptors.
Topics: Animals; Cells, Cultured; Central Nervous System Depressants; Convulsants; Kainic Acid; Phenobarbital; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Stereoisomerism; Temperature; Thiopental | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Recurrence; Tetanus Toxin | 2001 |
Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.
Topics: Animals; Brain; Caffeine; Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Elapid Venoms; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine; Kainic Acid; Male; Mice; Neuroprotective Agents; Phenobarbital; Phosphodiesterase Inhibitors; Quinolinic Acid; Receptors, Purinergic P1 | 2001 |
Phenobarbital pre-treatment prevents kainic acid-induced impairments in acquisition learning.
Topics: Animals; Behavior, Animal; Cues; Excitatory Amino Acid Agonists; GABA Modulators; Kainic Acid; Learning; Male; Maze Learning; Memory; Phenobarbital; Rats; Rats, Long-Evans; Seizures | 2000 |
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats.
Topics: Acute Disease; Aggression; Animals; Anticonvulsants; Creatine; Creatinine; Dietary Supplements; Emotions; Hippocampus; Kainic Acid; Learning Disabilities; Male; Neuroprotective Agents; Phenobarbital; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Status Epilepticus | 2004 |
Sequential changes of nitric oxide levels in the temporal lobes of kainic acid-treated mice following application of nitric oxide synthase inhibitors and phenobarbital.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Phenobarbital; Spectrometry, Fluorescence; Temporal Lobe | 2005 |
NKCC1 transporter facilitates seizures in the developing brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Bumetanide; Cerebral Cortex; Diuretics; Electroencephalography; Gene Expression Regulation, Developmental; Hippocampus; Humans; Immunohistochemistry; Infant; Kainic Acid; Membrane Potentials; Phenobarbital; Rats; Rats, Long-Evans; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2005 |
Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Hypnotics and Sedatives; Kainic Acid; Kindling, Neurologic; Male; Muscarinic Agonists; Pentylenetetrazole; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Rhodamine 123; Up-Regulation | 2007 |
A KCNQ channel opener for experimental neonatal seizures and status epilepticus.
Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Female; Flurothyl; Kainic Acid; KCNQ Potassium Channels; Male; Phenobarbital; Pregnancy; Rats; Seizures; Spectrum Analysis; Status Epilepticus; Time Factors | 2009 |
The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats.
Topics: Animals; Anticonvulsants; Cognition Disorders; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Hippocampus; Hyperkinesis; Kainic Acid; Phenobarbital; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2013 |
Antioxidant, anticonvulsive and neuroprotective effects of dapsone and phenobarbital against kainic acid-induced damage in rats.
Topics: Animals; Anticonvulsants; Antioxidants; Cell Death; Dapsone; Glutathione; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Neuroprotective Agents; Phenobarbital; Rats; Rats, Wistar | 2013 |
Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models.
Topics: Animals; Anticonvulsants; Basolateral Nuclear Complex; Bumetanide; Disease Models, Animal; Drug Synergism; Electric Stimulation; Kainic Acid; Lithium; Male; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Seizures | 2018 |
Functional characterization of novel bumetanide derivatives for epilepsy treatment.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Bumetanide; Convulsants; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Kainic Acid; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2 | 2020 |
Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital.
Topics: Animals; Anticonvulsants; Body Weight; Convulsants; Cost of Illness; Disease Models, Animal; Drug Compounding; Drug Discovery; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Temporal Lobe; Everolimus; High-Throughput Screening Assays; Kainic Acid; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Seizures; Translational Research, Biomedical | 2021 |