Page last updated: 2024-09-02

kahweol and dinoprostone

kahweol has been researched along with dinoprostone in 3 studies

Compound Research Comparison

Studies
(kahweol)
Trials
(kahweol)
Recent Studies (post-2010)
(kahweol)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
11895529,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomykahweol (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jeong, HG; Kim, DH; Kim, JY1
Cho, JY; Kim, SH; Lee, J; Park, YC; Shen, T1
Azevedo, AO; Caliari, MV; Duarte, ID; Guzzo, LS; Perez, AC; Queiroz-Junior, CM; Romero, TR1

Other Studies

3 other study(ies) available for kahweol and dinoprostone

ArticleYear
Inhibitory effect of the coffee diterpene kahweol on carrageenan-induced inflammation in rats.
    BioFactors (Oxford, England), 2006, Volume: 26, Issue:1

    Topics: Air; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Count; Coffee; Cyclooxygenase 2 Inhibitors; Dinoprostone; Diterpenes; Edema; Enzyme Inhibitors; Exudates and Transudates; Foot; Inflammation; Male; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2006
Nuclear factor-kappaB/signal transducers and activators of transcription-1-mediated inflammatory responses in lipopolysaccharide-activated macrophages are a major inhibitory target of kahweol, a coffee diterpene.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:7

    Topics: Animals; Base Sequence; Blotting, Western; Coffee; Dinoprostone; Diterpenes; DNA Primers; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT1 Transcription Factor

2010
Involvement of endogenous opioid peptides in the peripheral antinociceptive effect induced by the coffee specific diterpene kahweol.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:5

    Topics: Analgesics; Animals; beta-Endorphin; Coffee; Dinoprostone; Diterpenes; Hyperalgesia; Leucine; Male; Naloxone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Peptides; Pressure; Rats; Rats, Wistar; Skin

2015