kaempferol-3-o-rhamnoside has been researched along with astragalin* in 2 studies
2 other study(ies) available for kaempferol-3-o-rhamnoside and astragalin
| Article | Year |
|---|---|
Determination of Afzelin and Astragalin from Lespedeza cuneata on Aldose Reductase Inhibition.
The bioactive chemicals in L. cuneata were investigated by repeated column chromatography and their effect on aldose reductase (AR), obtained from rat lenses, was examined. Results showed that the ethyl acetate and n-butanol fractions of L. cuneata exhibited potential inhibitory effect against AR with IC50 values of 0.57 and 0.49 μg/mL, respectively. Phytochemical analysis of these two fractions resulted in the isolation of five flavonoids namely, acacetin (1), afzelin (2), astragalin (3), kaempferol (4) and scutellarein 7-O-glucoside (5). The AR inhibitory effect of compounds 1-5 was explored; compounds 2, 3 and 5 showed potential AR-inhibitory effects with IC50 values of 2.20, 1.91 and 12.87 μM, respectively. Quantitative analysis of afzelin (2) and astragalin (3) in L. cuneata by high performance liquid chromatography with ultraviolet detection revealed its content to be 0.722-11.828 and 2.054-7.006 mg/g, respectively. Overall, this study showed that L. cuneata is rich in flavonoids with promising AR-inhibitory activities, which can be utilized for the development of natural therapies for treating and managing diabetic complications. Topics: Aldehyde Reductase; Animals; Flavonoids; Kaempferols; Lens, Crystalline; Lespedeza; Mannosides; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley | 2021 |
[Studies on flavonoids from the leaves of Lindera aggregata].
To investigate the chemical constituents in the leaves of Lindera aggregate.. Compounds were separated by column chromatography with silica gel and ODS. The structures were identified by physicochemical properties and spectral analysis (1H-NMR, 13C-NMR).. Eight compounds were isolated and identified as: quercetin-3-O-L-rhamnoside(1), kaempferol-3-O-L-rhamnoside(2), kaempferol(3), dihydrokaempferol-3-O-L-rhamnoside (4), quercetin (5), quercetin-3-O-alpha-D-arabinofuranoside (6), quercetin-3-O-alpha-D-glucopyranoside(7), kaempferol-3-O-D-glucopyranoside(8).. Compounds 2,4 and 8 are obtained from Lindera aggregata for the first time. Topics: Flavonoids; Glycosides; Kaempferols; Lindera; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Leaves; Plants, Medicinal; Quercetin | 2011 |