kadsurenone has been researched along with lignans in 41 studies
| Studies (kadsurenone) | Trials (kadsurenone) | Recent Studies (post-2010) (kadsurenone) | Studies (lignans) | Trials (lignans) | Recent Studies (post-2010) (lignans) |
|---|---|---|---|---|---|
| 51 | 0 | 3 | 7,024 | 95 | 4,172 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (68.29) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 3 (7.32) | 29.6817 |
| 2010's | 2 (4.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottlieb, OR | 1 |
| Chen, CC; Huang, TF; Huang, YL; Teng, CM; Yu, SM | 1 |
| Hussaini, IM; Shen, TY | 1 |
| Chen, CC; Huang, TF; Huang, YL; Lin, CH; Teng, CM; Tsai, CW; Yu, SM | 1 |
| Audry, E; Braquet, P; Colleter, JC; Croizet, F; Dallet, P; Dubost, JP; Langlois, MH | 1 |
| Dillon, PK; Durán, WN | 1 |
| Gustafson, KS; Jacob, HS; Nelson, RD; Vercellotti, GM; Yin, HQ | 1 |
| Bittner, C; Lambrecht, G; Parnham, MJ | 1 |
| Dutka, AJ; Hallenbeck, JM; Kochanek, PM; Kumaroo, KK | 1 |
| Dillon, PK; Durán, WN; Ritter, AB | 1 |
| Felsen, D; Freund, RM; Vaughan, ED; Weisman, SM | 1 |
| Chang, MN; Doebber, TW; Han, GQ; Hwang, SB; Lam, MH; Li, RZ; Shen, TY; Wang, X; Wu, MS | 1 |
| Chang, MN; Choy, BM; Doebber, TW; Robbins, JC; Shen, TY; Wu, MS | 1 |
| Chang, MN; Doebber, TW; Hwang, SB; Lam, MH; Shen, TY; Wang, X; Wu, MS | 1 |
| Beattie, TR; Biftu, T; Hwang, SB; Lam, MH; Shen, TY | 1 |
| Hwang, SB; Lam, MH; Pong, SS | 1 |
| Lambrecht, G; Parnham, MJ | 1 |
| Tokumura, A; Tsukatani, H | 1 |
| Darius, H; Lefer, AM; Smith, JB | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Hwang, SB; Lam, MH | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Mariano, F; Montrucchio, G; Tetta, C | 1 |
| Brooker, DR; Bugianesi, RL; Hwang, SB; Ponpipom, MM; Shen, TY; Yue, BZ | 1 |
| Benveniste, J; Braquet, P; Chignard, M; Korth, R; Le Couedic, JP; Norel, X; Nunez, D; Spinnewyn, B | 1 |
| Darius, H; Lefer, AM | 1 |
| Braquet, P; Neuwirth, R; Satriano, JA; Schlondorff, D; Singhal, P | 1 |
| Debs, RJ; Philip, R; Valone, FH | 1 |
| Baggiolini, M; Dewald, B | 1 |
| Rainsford, KD | 1 |
| Dideberg, O; Dupont, L; Germain, G | 1 |
| Chang, MN; Han, GQ; Hwang, SB; Li, CL; Li, SM; Springer, JP | 1 |
| Hwang, SB; Lam, MH; Li, CL; Shen, TY | 2 |
| Han, GQ; Ma, Y; Wang, YY | 1 |
| Chen, ZN | 1 |
| Huang, TF; Hung, ML; Ko, FN; Teng, CM; Tsai, IH | 1 |
| Akai, S; Iio, K; Kita, Y; Morita, N; Nakamura, Y | 1 |
| Li, X; Luo, H | 1 |
| Huang, SP; Lin, LC; Tsai, TH; Wu, YT | 1 |
| Dong, N; Li, R; Shi, D; Wang, H; Yu, H; Zhang, N; Zhang, S | 1 |
| Chen, YH; Ding, DD; Kong, Y; Li, Y; Long, CL; Luo, JF; Mei, RQ; Wang, YH; Yang, J | 1 |
4 review(s) available for kadsurenone and lignans
| Article | Year |
|---|---|
The rational search for natural neolignans.
Topics: Benzofurans; Drug Design; Lignans; Lignin; Molecular Structure; Plants, Medicinal; Platelet Activating Factor | 1991 |
[Antagonists of platelet activating factor].
Topics: Animals; Benzofurans; Benzopyrans; Depression, Chemical; Guinea Pigs; Lignans; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Thiazoles | 1985 |
[Recent progress in the study of anti-PAF (platelet activating factor) constituents of medicinal herbs].
Topics: Animals; Asthma; Benzofurans; Diterpenes; Drugs, Chinese Herbal; Furans; Ginkgolides; Humans; Lactones; Lignans; Plant Extracts; Platelet Activating Factor | 1993 |
[Advances in pharmacological study of Piper kadsura (Choisy) Ohwi].
Topics: Animals; Benzofurans; Cerebrovascular Circulation; Drugs, Chinese Herbal; Humans; Lignans; Neuroprotective Agents; Piper; Plant Stems; Plants, Medicinal; Platelet Activating Factor | 2002 |
37 other study(ies) available for kadsurenone and lignans
| Article | Year |
|---|---|
Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone.
Topics: Animals; Benzofurans; Blood Platelets; Calcium; Collagen; In Vitro Techniques; Lignans; Molecular Structure; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Rabbits; Stereoisomerism; Thrombin; Thromboxane B2 | 1990 |
Kadsurenone and other related lignans as antagonists of platelet-activating factor receptor.
Topics: Benzofurans; Cell Membrane; Drugs, Chinese Herbal; Humans; Kinetics; Lignans; Lignin; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 1990 |
Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii.
Topics: Animals; Aorta, Thoracic; Benzofurans; Caffeine; Calcium; Calcium Radioisotopes; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Epoprostenol; In Vitro Techniques; Lignans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains | 1990 |
Lipophilicity force field profile: an expressive visualization of the lipophilicity molecular potential gradient.
Topics: Benzofurans; Computer Graphics; Diterpenes; Fats; Ginkgolides; Lactones; Lignans; Mathematics; Models, Molecular; Solubility | 1990 |
Effect of platelet-activating factor on microvascular permselectivity: dose-response relations and pathways of action in the hamster cheek pouch microcirculation.
Topics: Animals; Benzofurans; Blood Pressure; Capillary Permeability; Cheek; Cricetinae; Dexamethasone; Dextrans; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluoresceins; Hematocrit; Indomethacin; Lignans; Macromolecular Substances; Male; Mesocricetus; Methacrylates; Microcirculation; Platelet Activating Factor | 1988 |
Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage.
Topics: Benzofurans; Cell Aggregation; Cell Survival; Diterpenes; Endothelium, Vascular; Fetal Hemoglobin; Furans; Ginkgolides; Hemoglobins, Abnormal; Humans; Inflammation; Lactones; Lignans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides | 1988 |
Antagonism of platelet activating factor-induced chemiluminescence in guinea-pig peritoneal macrophages in differing states of activation.
Topics: Alprazolam; Animals; Benzofurans; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Lignans; Luminescent Measurements; Macrophage Activation; Macrophages; Male; Platelet Activating Factor; Thiazoles | 1989 |
Platelet activating factor receptor blockade enhances recovery after multifocal brain ischemia.
Topics: Animals; Benzofurans; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Dogs; Evoked Potentials, Somatosensory; Lignans; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1987 |
Vasoconstrictor effects of platelet-activating factor in the hamster cheek pouch microcirculation: dose-related relations and pathways of action.
Topics: Animals; Arterioles; Benzofurans; Blood Pressure; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hematocrit; Lignans; Male; Mesocricetus; Microcirculation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Vasoconstriction | 1988 |
Differential effect of platelet-activating factor (PAF) receptor antagonists on peptide and PAF-stimulated prostaglandin release in unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Benzofurans; Dinoprostone; Kidney; Lignans; Male; Peptides; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins E; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Triazolam; Ureteral Obstruction | 1988 |
Characterization of a platelet-activating factor receptor antagonist isolated from haifenteng (Piper futokadsura): specific inhibition of in vitro and in vivo platelet-activating factor-induced effects.
Topics: Animals; Benzofurans; Benzopyrans; Capillary Permeability; Guinea Pigs; Humans; Lignans; Magnoliopsida; Mathematics; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1985 |
Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF-receptor antagonist kadsurenone.
Topics: Animals; Benzofurans; Benzopyrans; Endotoxins; Escherichia coli; Female; Hypotension; Kinetics; Lignans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1985 |
The isolation and characterization of kadsurenone from haifenteng (Piper futokadsura) as an orally active specific receptor antagonist of platelet-activating factor.
Topics: Animals; Benzofurans; Benzopyrans; Binding, Competitive; Capillary Permeability; Guinea Pigs; Humans; Lignans; Lysosomes; Neutrophils; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1985 |
trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.
Topics: Animals; Benzofurans; Benzopyrans; Blood Platelets; Bradykinin; Capillary Permeability; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Furans; Histamine; Humans; Lignans; Magnesium; Mathematics; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sodium; Thiazoles | 1985 |
Ionic and GTP regulation of binding of platelet-activating factor to receptors and platelet-activating factor-induced activation of GTPase in rabbit platelet membranes.
Topics: Animals; Benzofurans; Benzopyrans; Calcium; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; Guanosine Triphosphate; Kinetics; Lignans; Magnesium; Manganese; Platelet Activating Factor; Platelet Membrane Glycoproteins; Potassium; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sodium; Temperature | 1986 |
Kadsurenone distinguishes between different platelet activating factor receptor subtypes on macrophages and polymorphonuclear leucocytes.
Topics: Animals; Benzofurans; Benzopyrans; Cell Aggregation; Guinea Pigs; Lignans; Luminescent Measurements; Macrophages; Male; Neutrophils; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Swine | 1986 |
Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists.
Topics: Alprazolam; Anaphylaxis; Animals; Benzodiazepines; Benzofurans; Benzopyrans; Diphenhydramine; Guinea Pigs; Histamine; Lignans; Male; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Species difference in the specific receptors of platelet activating factor.
Topics: Animals; Benzofurans; Blood Platelets; Cell Membrane; Diterpenes; Furans; Ginkgolides; Humans; Lactones; Lignans; Lung; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Thiazoles; Thiophenes | 1986 |
Cardiovascular alterations in the rabbit infused with platelet activating factor (PAF): effect of kadsurenone, a PAF-receptor antagonist.
Topics: Animals; Benzofurans; Cardiovascular Physiological Phenomena; Cardiovascular System; Electrocardiography; Female; Hemodynamics; Lignans; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1986 |
Structure-activity relationships of kadsurenone analogues.
Topics: Animals; Benzofurans; Blood Platelets; Cell Membrane; Circular Dichroism; Indicators and Reagents; Kinetics; Lignans; Magnetic Resonance Spectroscopy; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 1987 |
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Benzofurans; Benzopyrans; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lignans; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thiazoles | 1986 |
Pharmacologic antagonism of platelet activating factor and peptide leukotrienes inhibits guinea pig anaphylaxis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Blood Pressure; Diphenhydramine; Guinea Pigs; In Vitro Techniques; Lignans; Lung; Male; Platelet Activating Factor; Platelet Count; Pyrazoles | 1987 |
Effect of platelet activating factor antagonists on cultured rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Cells, Cultured; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Glomerular Mesangium; Lactones; Lignans; Male; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Rats; Thiazoles | 1987 |
Enhanced human monocyte cytotoxicity by platelet-activating factor.
Topics: Benzofurans; Cells, Cultured; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Humans; Isomerism; Lignans; Monocytes; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1988 |
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay.
Topics: Benzofurans; Diterpenes; Exocytosis; Fluorescence; Ginkgolides; Humans; Lactones; Lignans; Methods; Neutrophils; Pancreatic Elastase; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Pyridines; Thiazoles | 1987 |
Relative roles of leukotrienes and platelet activating factor in experimentally-induced gastric ulceration.
Topics: Animals; Aspirin; Benzofurans; Ethanol; Gastric Mucosa; Intestinal Mucosa; Lignans; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer | 1986 |
Crystal and molecular structure of BN 52021, a PAF-acether antagonist. Comparison with the conformation of Kadsurenone and related compounds.
Topics: Benzofurans; Chemical Phenomena; Chemistry, Physical; Crystallization; Diterpenes; Ginkgolides; Lactones; Lignans; Molecular Conformation; Plant Extracts; Platelet Activating Factor; Temperature | 1986 |
[Neolignans from Piper hancei Maxim].
Topics: Alkaloids; Benzofurans; Chemical Phenomena; Chemistry; Lignans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plant Extracts; Plants, Medicinal; Platelet Activating Factor | 1986 |
Characterization of cutaneous vascular permeability induced by platelet-activating factor in guinea pigs and rats and its inhibition by a platelet-activating factor receptor antagonist.
Topics: Animals; Benzofurans; Benzopyrans; Binding Sites; Bradykinin; Cell Membrane Permeability; Cyclooxygenase Inhibitors; Drug Interactions; Female; Guinea Pigs; Histamine; Indomethacin; Lignans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Skin; Species Specificity; Tritium | 1985 |
Release of platelet activating factor and its involvement in the first phase of carrageenin-induced rat foot edema.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Benzopyrans; Carrageenan; Edema; Lignans; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Time Factors | 1986 |
[PAF antagonistic benzofuran neolignans from Piper kadsura].
Topics: Benzofurans; Bridged Bicyclo Compounds; Drugs, Chinese Herbal; Humans; Lignans; Molecular Structure; Platelet Activating Factor; Stereoisomerism | 1993 |
Trimucytin: a collagen-like aggregating inducer isolated from Trimeresurus mucrosquamatus snake venom.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Benzofurans; Calcium; Collagen; Crotalid Venoms; Lignans; Molecular Sequence Data; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Proteoglycans; Rabbits; Sequence Homology, Amino Acid; Thromboxane A2 | 1993 |
Ambident effect of a p-sulfinyl group for the introduction of two carbon substituents to phenol rings: a convergent synthesis of diverse benzofuran neolignans.
Topics: Benzofurans; Ligands; Lignans; Lithium; Phenols; Sulfinic Acids | 2000 |
Pharmacokinetics of kadsurenone and its interaction with cyclosporin A in rats using a combined HPLC and microdialysis system.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzofurans; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Data Interpretation, Statistical; Drugs, Chinese Herbal; Lignans; Male; Microdialysis; Piper; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Development of an LC-MS/MS method for quantification of kadsurenone in rat plasma and its application to a pharmacokinetic study.
Topics: Animals; Benzofurans; Chromatography, Liquid; Least-Squares Analysis; Lignans; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2013 |
Amides and neolignans from the aerial parts of Piper bonii.
Topics: Alkaloids; Amides; Benzofurans; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Glycosides; Humans; Inhibitory Concentration 50; Lignans; Molecular Structure; Piper; Piperidines; Plant Components, Aerial; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Tirofiban; Tyrosine | 2016 |