justicidin a has been researched along with lignans in 33 studies
| Studies (justicidin a) | Trials (justicidin a) | Recent Studies (post-2010) (justicidin a) | Studies (lignans) | Trials (lignans) | Recent Studies (post-2010) (lignans) |
|---|---|---|---|---|---|
| 45 | 0 | 22 | 7,024 | 95 | 4,172 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (39.39) | 29.6817 |
| 2010's | 16 (48.48) | 24.3611 |
| 2020's | 4 (12.12) | 2.80 |
| Authors | Studies |
|---|---|
| Alfermann, AW; Mohagheghzadeh, A; Schmidt, TJ | 1 |
| Chung, MI; Day, SH; Ko, HH; Lee, JC; Lin, CN; Lin, YC; Tsai, ML; Tsao, LT; Wang, JP; Won, SJ | 1 |
| Brun, R; Gertsch, J; Heilmann, J; Sticher, O; Tobler, RT | 1 |
| Lin, CN; Tsao, LT; Wang, JP | 1 |
| Ionkova, I; Nedialkov, P; Ninov, S; Vasilev, N | 1 |
| Huang, CW; Lee, CH; Lee, JC; Lin, CN; Liu, HS; Su, CL; Won, SJ | 1 |
| Chen, J; Guo, Y; Jin, Y; Wu, J; Xu, X; Yang, M | 1 |
| Cheng, F; Wu, J; Yang, M; Zhou, Y | 1 |
| Huang, LL; Huang, LM; Lee, JC; Lin, CN; Su, CL; Won, SJ | 1 |
| Bos, R; Ionkova, I; Kayser, O; Konstantinov, S; Momekov, G; Vasilev, N | 1 |
| Fuss, E; Hemmati, S; Schmidt, TJ | 1 |
| da Silva, R; Donate, PM; Ruas, MM | 1 |
| El-Gendy, MM; Hawas, UW; Jaspars, M | 1 |
| Dineva, I; Ionkova, I; Konstantinov, S; Momekov, G | 1 |
| Balamurugan, R; Gudla, V | 1 |
| Argade, NP; Patel, RM | 1 |
| Hu, Y; Kong, W; Luo, J; Yang, M | 1 |
| Atanasova, T; Ilieva, Y; Ionkova, I; Konstantinov, S; Sasheva, P; Zaharieva, MM; Zhelezova, I | 1 |
| Jiang-Shieh, YF; Lan, SH; Lin, CN; Liu, HS; Su, CL; Won, SJ; Wu, SY; Yen, CH | 1 |
| Guenova, M; Ionkov, T; Ionkova, I; Konstantinov, S; Michova, A; Momekov, G; Sacheva, P; Stoyanov, N; Yossifov, D | 1 |
| Chang, TY; Cheng, HL; Chow, NH; Chuang, JJ; Lee, CT; Liu, HS; Tsai, HW; Tzai, TS; Wang, YW; Won, SJ | 1 |
| Kao, TT; Lin, CC; Shia, KS | 1 |
| Kant, R; Narender, T; Naresh, G | 1 |
| Gu, MY; Kim, J; Yang, HO | 1 |
| Hemmati, S; Seradj, H | 1 |
| Hu, Y; Luo, J; Qin, J; Yang, M | 1 |
| Barak, LS; Bock, CB; Caron, MG; Lubkov, V; Lyerly, HK; Pack, TF; Ray, C; Rochelle, LK; Snyder, JC; Waggoner, AS | 1 |
| Choi, Y; Lee, H; Yoon, J; Youm, J | 1 |
| Ai, Z; Hao, P; Liu, B; Sun, Y; Wu, H; Wu, S; Xiao, W; Xie, Z; Xiong, W; Yang, Y | 1 |
| Abrunhosa-Thomas, I; Akssira, M; Chalard, P; Daniellou, R; Ketatni, EM; Khouili, M; Ourhzif, EM; Pâris, A; Troin, Y | 1 |
| Alfieri, M; Consonni, R; Cusano, E; Dougué Kentsop, RA; Faoro, F; Laura, M; Lauria, M; Locatelli, F; Mascheretti, I; Mattana, M; Ottolina, G | 1 |
| Choi, P; Ham, J; Jeong, KH; Ju, HN; Kim, JY; Kim, T; Kim, YJ; Kwon, H; Park, YT; Yoon, CH | 1 |
| Hong, Z; Liu, B; Lu, Y; Wu, H; Xie, Z; Yang, Y; Yao, Y; Zhang, T; Zhang, Y | 1 |
1 review(s) available for justicidin a and lignans
| Article | Year |
|---|---|
Justicidin B: A Promising Bioactive Lignan.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antiprotozoal Agents; Biological Products; Biosynthetic Pathways; Biotechnology; Chemistry; Dioxolanes; Humans; Lignans; Metabolomics; Plant Extracts; Platelet Aggregation Inhibitors; Toxicity Tests | 2016 |
32 other study(ies) available for justicidin a and lignans
| Article | Year |
|---|---|
Arylnaphthalene lignans from in vitro cultures of Linum austriacum.
Topics: Chromatography, High Pressure Liquid; Dioxolanes; Flax; Iran; Lactones; Lignans; Mass Spectrometry; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Seeds | 2002 |
Potent cytotoxic lignans from Justicia procumbens and their effects on nitric oxide and tumor necrosis factor-alpha production in mouse macrophages.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Line, Transformed; Dioxolanes; Drug Screening Assays, Antitumor; Glycosides; Inhibitory Concentration 50; Lignans; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Spectrophotometry, Ultraviolet; Taiwan; Tumor Necrosis Factor-alpha | 2002 |
Antifungal, antiprotozoal, cytotoxic and piscicidal properties of Justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Dioxolanes; Humans; Inhibitory Concentration 50; Lethal Dose 50; Lignans; Mitosporic Fungi; Phyllanthus; Phytotherapy; Plant Extracts; Plasmodium; Rats; Trypanosoma; Tumor Cells, Cultured; Zebrafish | 2003 |
Justicidin A inhibits the transport of tumor necrosis factor-alpha to cell surface in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Topics: Animals; Biological Transport; Cell Line; Dioxolanes; Drug Interactions; Gene Expression; Interleukin-6; Lignans; Lipopolysaccharides; Macrophages; Mice; RNA, Messenger; Tumor Necrosis Factor-alpha | 2004 |
HPTLC densitomeric determination of justicidin B in Linum in vitro cultures.
Topics: Cells, Cultured; Chromatography, Thin Layer; Densitometry; Dioxolanes; Flax; Lignans; Spectrophotometry, Ultraviolet | 2004 |
Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.
Topics: Animals; Antigens, Nuclear; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclosporine; Cytoplasm; Dioxolanes; DNA-Binding Proteins; Female; G1 Phase; Humans; Ku Autoantigen; Lignans; Mice; Mice, Nude; Mitochondria; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Uterine Cervical Neoplasms | 2005 |
A new lignan from the Jian-er syrup and its content determination by RP-HPLC.
Topics: Apocynaceae; Chromatography, High Pressure Liquid; Dioxolanes; Drugs, Chinese Herbal; Lignans; Molecular Structure; Plants, Medicinal; Reproducibility of Results | 2006 |
Complete assignments of 1H and 13C NMR data for seven arylnaphthalide lignans from Justicia procumbens.
Topics: Acanthaceae; Dioxolanes; Lignans; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Molecular Structure; Naphthalenes | 2006 |
Caspase-8 acts as a key upstream executor of mitochondria during justicidin A-induced apoptosis in human hepatoma cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cell Proliferation; Cytochromes c; Dioxolanes; Down-Regulation; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lignans; Liver Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Mitochondrial Proteins; Proto-Oncogene Proteins c-bcl-2; Up-Regulation; Xenograft Model Antitumor Assays | 2006 |
Production of justicidin B, a cytotoxic arylnaphthalene lignan from genetically transformed root cultures of Linum leonii.
Topics: Antineoplastic Agents, Phytogenic; Dioxolanes; Drug Screening Assays, Antitumor; Flax; France; Inhibitory Concentration 50; Lignans; Molecular Structure; Plant Roots; Plants, Genetically Modified; Plants, Medicinal | 2006 |
(+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B.
Topics: Base Sequence; Blotting, Southern; Catalysis; Cloning, Molecular; Dioxolanes; DNA, Plant; Escherichia coli; Flax; Furans; Gene Expression Regulation, Plant; Gene Silencing; Genes, Plant; Genome, Plant; Lignans; Plant Proteins; Plant Roots; RNA, Messenger | 2007 |
Complete assignments of (1)H and (13)C NMR spectral data for arylnaphthalene lignan lactones.
Topics: Carbon Isotopes; Dioxolanes; Lactones; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Naphthalenes; Protons | 2007 |
Novel bioactive metabolites from a marine derived bacterium Nocardia sp. ALAA 2000.
Topics: Anthraquinones; Anti-Bacterial Agents; Antifungal Agents; Chromatography; Coumarins; Crystallography, X-Ray; Dioxolanes; Egypt; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Laurencia; Lignans; Microbial Sensitivity Tests; Molecular Structure; Nocardia | 2008 |
Effect of justicidin B - a potent cytotoxic and pro-apoptotic arylnaphtalene lignan on human breast cancer-derived cell lines.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Dioxolanes; DNA Fragmentation; Female; Humans; Inhibitory Concentration 50; Lignans | 2011 |
Synthesis of arylnaphthalene lignan scaffold by gold-catalyzed intramolecular sequential electrophilic addition and benzannulation.
Topics: Biological Factors; Catalysis; Cyclization; Dioxolanes; Gold Compounds; Lactones; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Naphthalenes; Stereoisomerism | 2011 |
Palladium-promoted [2 + 2 + 2] cocyclization of arynes and unsymmetrical conjugated dienes: synthesis of justicidin B and retrojusticidin B.
Topics: Catalysis; Cyclization; Dioxolanes; Lignans; Molecular Structure; Naphthalenes; Palladium | 2013 |
Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents.
Topics: Acanthaceae; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Proliferation; Cell Survival; Dioxolanes; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Lignans; Naphthalenes; Signal Transduction; Structure-Activity Relationship; Superoxide Dismutase | 2014 |
Cytotoxic effect of the biotechnologically-derived justicidin B on human lymphoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Dioxolanes; Etoposide; Female; Humans; Lignans; Lymphoma; Male; Mice; NF-kappa B | 2014 |
Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Topics: Adenine; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Colorectal Neoplasms; Dioxolanes; HT29 Cells; Humans; Lignans; Mice; Mice, SCID; Microtubule-Associated Proteins; Phosphatidylinositol 3-Kinases; RNA, Small Interfering; Signal Transduction | 2015 |
Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bioreactors; Biotechnology; Caspases; Dioxolanes; Flax; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lignans; Mitochondria; Plant Roots; Signal Transduction | 2014 |
Antiangiogenesis as the novel mechanism for justicidin A in the anticancer effect on human bladder cancer.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dioxolanes; Heterografts; Humans; Lignans; Male; Mice, SCID; Neoplasm Transplantation; Urinary Bladder Neoplasms | 2015 |
The Total Synthesis of Retrojusticidin B, Justicidin E, and Helioxanthin.
Topics: Catalysis; Cyclization; Dioxolanes; Lignans; Molecular Structure; Naphthalenes | 2015 |
Silver(I)-Catalyzed Regioselective Construction of Highly Substituted α-Naphthols and Its Application toward Expeditious Synthesis of Lignan Natural Products.
Topics: Alkynes; Antineoplastic Agents; Benzodioxoles; Biological Products; Catalysis; Dioxolanes; Lignans; Molecular Structure; Naphthalenes; Naphthols; Silver; Stereoisomerism | 2015 |
The Neuroprotective Effects of Justicidin A on Amyloid Beta25-35-Induced Neuronal Cell Death Through Inhibition of Tau Hyperphosphorylation and Induction of Autophagy in SH-SY5Y Cells.
Topics: Amyloid beta-Peptides; Autophagy; Cell Death; Cell Line, Tumor; Cell Survival; Dioxolanes; Dose-Response Relationship, Drug; Humans; Lignans; Neurons; Neuroprotective Agents; Peptide Fragments; Phosphorylation; tau Proteins | 2016 |
Ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry and pharmacokinetic analysis of justicidin B and 6'-hydroxy justicidin C in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Dioxolanes; Half-Life; Lignans; Limit of Detection; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2017 |
Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.
Topics: Adenosine Triphosphatases; Animals; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Clathrin; Dioxolanes; Endocytosis; Epithelium; Female; Homeostasis; Humans; Leucine; Lignans; Mice; Mice, Inbred C57BL; Protein Isoforms; Rats; Receptors, G-Protein-Coupled; Stem Cells; Stochastic Processes; Wnt Signaling Pathway | 2017 |
DW2008S and its major constituents from Justicia procumbens exert anti-asthmatic effect via multitargeting activity.
Topics: Animals; Anti-Asthmatic Agents; Antibodies, Neutralizing; Asthma; Cyclic Nucleotide Phosphodiesterases, Type 4; Dioxolanes; Disease Models, Animal; Female; Inflammation; Justicia; Lignans; Mice, Inbred BALB C; Plant Extracts; Protective Agents; Receptor, Adenosine A3; Receptors, Immunologic; Th2 Cells | 2018 |
A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) Nees.
Topics: Acanthaceae; Benzene Derivatives; Dioxolanes; Dose-Response Relationship, Drug; Ethers; Humans; Lignans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Structure-Activity Relationship | 2019 |
Design, synthesis, and evaluation of cytotoxic activities of arylnaphthalene lignans and aza-analogs.
Topics: Antineoplastic Agents; Aza Compounds; Cell Line, Tumor; Dioxolanes; Humans; Inhibitory Concentration 50; Lactones; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Naphthalenes; Phytochemicals; Structure-Activity Relationship | 2021 |
New Insight into Justicidin B Pathway and Production in
Topics: Dioxolanes; Flax; Gene Expression Profiling; Gene Expression Regulation, Plant; Lignans; Metabolic Networks and Pathways; Plant Proteins; Plant Roots; Transcriptome | 2021 |
The efficient synthesis and biological evaluation of justicidin B.
Topics: Animals; Cell Line; Dioxolanes; Humans; Lactones; Lignans; Mice | 2023 |
Reveals of candidate active ingredients in Justicia and its anti-thrombotic action of mechanism based on network pharmacology approach and experimental validation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Blood Platelets; Cells, Cultured; Chemokine CXCL12; Cyclic Nucleotide Phosphodiesterases, Type 5; Dioxolanes; Drug Discovery; Fibrinolytic Agents; Gene Regulatory Networks; Humans; Justicia; Lignans; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Protein Interaction Maps; Proto-Oncogene Proteins c-met; rac1 GTP-Binding Protein | 2021 |