jujuboside a has been researched along with beta-escin in 41 studies
| Studies (jujuboside a) | Trials (jujuboside a) | Recent Studies (post-2010) (jujuboside a) | Studies (beta-escin) | Trials (beta-escin) | Recent Studies (post-2010) (beta-escin) |
|---|---|---|---|---|---|
| 43 | 0 | 28 | 14,137 | 211 | 6,278 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 12 (29.27) | 29.6817 |
| 2010's | 18 (43.90) | 24.3611 |
| 2020's | 9 (21.95) | 2.80 |
| Authors | Studies |
|---|---|
| Lan, MY; Li, LF; Wu, SX; Xu, T; Zhang, JX; Zhao, SY | 1 |
| Li, Y; Ou, Y; Wang, Z; Zhou, X; Zhou, Y | 1 |
| Guo, DW; Shou, CH; Wang, J; Zheng, XX | 1 |
| Feng, Z; Shou, C; Wang, J; Zheng, X | 1 |
| Bi, KS; Che, ZT; Li, M; Li, YJ; Xu, ZM | 1 |
| Hong, D; Lu, Y; Ning, G; Shou, C; Zhang, M; Zheng, X | 1 |
| Bai, YJ; Cheng, G; Liu, Y; Ma, LB; Tao, J; Tu, GZ; Wang, B; Zhao, YY | 1 |
| Liang, H; Liu, MJ; Liu, QX; Wang, B; Zhao, YY | 1 |
| Lu, YJ; Zhang, HY; Zhang, SM; Zheng, XX; Zhou, J | 1 |
| Chen, MX; Wang, XL; Wang, ZF; Zhang, YJ | 1 |
| Wang, C; Xia, Q; Xia, Y; Xiong, T; Yao, DZ; You, ZL | 1 |
| Bollinger, L; Förstermann, U; Horke, S; Li, H; Steinkamp-Fenske, K; Xu, H; Yao, Y | 1 |
| Xie, J; Zhang, M; Zhang, Y | 1 |
| Kang, HS; Kim, CJ; Lee, JY; Moon, HJ; Park, BE; Sim, SS | 1 |
| He, JJ; Huang, J; Liang, FR; Tang, YJ; Xia, Q; Xu, CL; You, ZL; Zhang, WZ; Zhao, L | 1 |
| Sun, H; Wang, X; Yan, G; Yang, B; Zhang, A | 1 |
| He, S; Huang, X; Li, N; Li, Y; Liu, C; Mi, S; Wang, N; Zheng, X; Zhong, Y | 1 |
| Cheng, HP; Cui, HM; Dong, Y; Guo, LL; Huang, SJ; Wang, J; Wu, P; Zhang, CY | 1 |
| Kim, WI; Lee, JH; Son, JK; Woo, MH; Zhang, HY; Zhao, BT | 1 |
| Bi, KS; Jia, Y; Li, H; Liu, AJ; Liu, B; Liu, Z; Mao, X; Wu, B; Zhao, X | 1 |
| Goda, Y; Hakamatsuka, T; Hamato, A; Kamakura, H; Kang, DH; Maruyama, T; Oshima, N; Yamamoto, Y; Yokokura, T; Zaima, K | 1 |
| Ma, GI; Pang, GC; Wang, XX; Xie, JB | 1 |
| Liu, CY; Ren, Z; Zhao, HR | 1 |
| Ahibo Coffy, A; Alabdul Magid, A; Gangloff, SC; Gossan, DP; Josse, J; Morjani, H; Voutquenne-Nazabadioko, L; Yao-Kouassi, PA | 1 |
| Deng, Y; Geng, L; Li, H; Lin, F; Lu, Y; Miao, Y; Wu, L; Yu, S; Zhao, X | 1 |
| Ma, G; Song, P; Xie, J; Zhang, Y; Zhou, A | 1 |
| Qiao, HY; Qu, HH; Wang, QG; Xu, JK; Zhang, WK; Zhao, Y | 1 |
| Han, DD; Liu, FH; Mei, C; Wan, CR; Xia, ZF; Xu, JQ; Xu, XL; Yin, P | 1 |
| Du, CH; Feng, HX; Jia, JP; Li, Q; Qin, XM; Yan, Y | 1 |
| Du, H; Hou, J; Wang, C; Wang, Y; Yan, S; Yang, J; Zhang, X; Zhao, H; Zhu, L | 1 |
| Chen, J; Long, C; Misrani, A; Tabassum, S; Tang, BL; Yang, L | 1 |
| Chen, GH; Wu, CQ | 1 |
| Ali, A; Khan, MN; Musharraf, SG; Rahman, S; Ul Haq, F | 1 |
| Chu, C; Jiang, L; Li, H; Li, J; Lian, L; Liu, C; Yan, J; Zhu, L | 1 |
| Chen, Y; Huang, Q; Huang, Y; Huang, Z; Liu, Z; Lu, L; Qi, X; Wang, W; Wang, Y | 1 |
| Lei, M; Liang, X; Liu, Q; Luo, R; Peng, X; Wang, X; Zhong, Y; Zhu, J | 1 |
| Chen, JC; Cui, L; Kong, L; Li, H; Shang, DJ; Shi, YJ; Tian, JM; Tian, Y; Wang, C; Wen, CM; Xiao, HH; Yang, JX; Zhao, YM | 1 |
| Gong, J; Li, H; Li, J; Xie, X; Zhang, T | 1 |
| Chen, JC; Kong, L; Li, H; Tian, JM; Tian, Y; Wang, C; Wang, TM; Xiao, HH; Yang, JX; Zhang, Q; Zhao, YM | 1 |
| Cao, XY; Hao, SL; Ji, B; Jiang, ZZ; Kuang, XF; Li, L; Liu, YY; Lu, Q; Qian, ST; Wei, CJ; Xu, J; Yang, TT; Yin, XX; Yuan, JY | 1 |
| Chen, M; Dong, D; Dong, L; Du, J; Wu, B; Xiao, Y; Zhang, F; Zhang, L | 1 |
41 other study(ies) available for jujuboside a and beta-escin
| Article | Year |
|---|---|
[Effects of seeds, leaves and fruits of Ziziphus spinosa and jujuboside A on central nervous system function].
Topics: Animals; Drug Synergism; Drugs, Chinese Herbal; Female; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentobarbital; Phenylalanine; Rats; Rats, Wistar; Saponins; Sleep; Thiopental | 1993 |
1H NMR and spin-labeled EPR studies on the interaction of calmodulin with jujuboside A.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Calmodulin; Carbohydrate Sequence; Cattle; Electron Spin Resonance Spectroscopy; Hypnotics and Sedatives; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Saponins; Spin Labels | 1994 |
Inhibitory effect of jujuboside A on penicillin sodium induced hyperactivity in rat hippocampal CA1 area in vitro.
Topics: Animals; Drug Hypersensitivity; Drug Interactions; Female; Hippocampus; In Vitro Techniques; Male; Neurons; Penicillin G; Penicillins; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Saponins | 2001 |
The inhibitory effects of jujuboside A on rat hippocampus in vivo and in vitro.
Topics: Animals; Carbohydrate Sequence; Dentate Gyrus; Drugs, Chinese Herbal; Excitatory Postsynaptic Potentials; Female; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Injections, Intraventricular; Male; Molecular Sequence Data; Neurons; Penicillins; Plant Extracts; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Saponins; Seeds; Ziziphus | 2002 |
[Determination of jujubaside A in semen ziziphi spinosae by RP-HPLC].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Plants, Medicinal; Saponins; Ziziphus | 2001 |
Inhibitory effect of jujuboside A on glutamate-mediated excitatory signal pathway in hippocampus.
Topics: Animals; Calcium Signaling; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Glutamic Acid; Hippocampus; Hypnotics and Sedatives; Male; Penicillins; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Saponins; Seeds; Ziziphus | 2003 |
[Structure identification of jujuboside E].
Topics: Inosine; Molecular Conformation; Molecular Structure; Plants, Medicinal; Saponins; Seeds; Stearic Acids; Sucrose; Ziziphus | 2003 |
[Structure identification of jujuboside D].
Topics: Molecular Conformation; Molecular Structure; Phenylalanine; Plants, Medicinal; Saponins; Seeds; Ziziphus | 2004 |
Inhibitory effects of jujuboside A on EEG and hippocampal glutamate in hyperactive rat.
Topics: Animals; Behavior, Animal; Diazepam; Electroencephalography; Glutamic Acid; Hippocampus; Hyperkinesis; Male; Penicillins; Rats; Rats, Sprague-Dawley; Saponins | 2005 |
[Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets].
Topics: Drugs, Chinese Herbal; Ethanol; Flavones; Plants, Medicinal; Saponins; Seeds; Technology, Pharmaceutical; Ziziphus | 2005 |
Upregulation of Mark3 and Rpgrip1 mRNA expression by jujuboside A in mouse hippocampus.
Topics: Animals; Cytoskeletal Proteins; Hippocampus; Hypnotics and Sedatives; Male; Mice; Motor Activity; Protein Serine-Threonine Kinases; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saponins; Transcription, Genetic | 2007 |
Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.
Topics: Acetophenones; Betulinic Acid; Blotting, Western; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; NADPH Oxidase 4; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Pentacyclic Triterpenes; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Spermine; Triterpenes; Ziziphus | 2007 |
Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection.
Topics: Betulinic Acid; Biomarkers; Chromatography, High Pressure Liquid; Light; Medicine, Chinese Traditional; Molecular Structure; Pentacyclic Triterpenes; Reference Standards; Reproducibility of Results; Saponins; Scattering, Radiation; Temperature; Triterpenes; Volatilization; Ziziphus | 2008 |
Inhibitory effects of Geijigajakyak-Tang on trinitrobenzene sulfonic acid-induced colitis.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Benzoates; Bridged-Ring Compounds; Chemotaxis; Colitis; Cyclohexanols; Eucalyptol; Female; Glucosides; Glycyrrhizic Acid; Ileum; Lipid Peroxidation; Magnoliopsida; Malondialdehyde; Mice; Mice, Inbred BALB C; Models, Animal; Monoterpenes; Muscle Contraction; Muscle, Smooth; Neutrophils; Parasympatholytics; Peroxidase; Phytotherapy; Plant Extracts; Saponins; Trinitrobenzenesulfonic Acid; Triterpenes | 2009 |
Effects on the expression of GABAA receptor subunits by jujuboside A treatment in rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saponins | 2010 |
Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition approach.
Topics: Animals; Biomarkers, Tumor; Chromatography; Chromatography, High Pressure Liquid; Drosophila melanogaster; Humans; Mass Spectrometry; Metabolomics; Models, Biological; Models, Chemical; Multivariate Analysis; Pattern Recognition, Automated; Proteomics; Saponins; Signal Transduction; Sleep Initiation and Maintenance Disorders; Spectrometry, Mass, Electrospray Ionization; Temperature | 2012 |
An LC-MS/MS method for determination of jujuboside A in rat plasma and its application to pharmacokinetic studies.
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Humans; Male; Rats; Rats, Sprague-Dawley; Saponins; Tandem Mass Spectrometry; Ziziphus | 2012 |
[Species differentiation and quality assessment of Ziziphus jujuba var. spinosa based on the HPLC fingerprint and quantitative analysis].
Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Drug Contamination; Drugs, Chinese Herbal; Fruit; Illicit Drugs; Pentacyclic Triterpenes; Principal Component Analysis; Quality Control; Reproducibility of Results; Saponins; Seeds; Triterpenes; Ziziphus | 2012 |
Quantitative and pattern recognition analyses of magnoflorine, spinosin, 6'''-feruloyl spinosin and jujuboside A by HPLC in Zizyphi Semen.
Topics: Analgesics; Anticonvulsants; Aporphines; Chromatography, High Pressure Liquid; Disaccharides; Drugs, Chinese Herbal; Ethnopharmacology; Flavones; Flavonoids; Limit of Detection; Medicine, Korean Traditional; Nephelometry and Turbidimetry; Pattern Recognition, Automated; Plant Extracts; Quality Control; Reproducibility of Results; Saponins; Seeds; Species Specificity; Spectrophotometry, Ultraviolet; Tranquilizing Agents; Ziziphus | 2014 |
Jujuboside A, a neuroprotective agent from semen Ziziphi Spinosae ameliorates behavioral disorders of the dementia mouse model induced by Aβ 1-42.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Cognition; Dementia; Disease Models, Animal; Hippocampus; Male; Maze Learning; Mice; Neuroprotective Agents; Nitric Oxide; Peptide Fragments; Saponins; Ziziphus | 2014 |
Identification of marker compounds for Japanese Pharmacopoeia non-conforming jujube seeds from Myanmar.
Topics: Biomarkers; China; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Japan; Myanmar; Oleanolic Acid; Peptides, Cyclic; Pharmacopoeias as Topic; Plant Extracts; Saponins; Seeds; Ziziphus | 2015 |
Influence of JuA in evoking communication changes between the small intestines and brain tissues of rats and the GABAA and GABAB receptor transcription levels of hippocampal neurons.
Topics: Animals; Brain; Cytokines; Hypnotics and Sedatives; Intestinal Mucosa; Intestine, Small; Neurons; Rats; Receptors, GABA-A; Receptors, GABA-B; RNA, Messenger; Saponins; Tissue Culture Techniques | 2015 |
[Purification Technology Optimization for Saponins from Ziziphi Spinosae Semen with Macroporous Adsorption Resin by Box-Behnken Design-Response Surface Methodology].
Topics: Adsorption; Drugs, Chinese Herbal; Ethanol; Resins, Plant; Saponins; Seeds; Solvents; Technology, Pharmaceutical; Water; Ziziphus | 2015 |
Triterpene glycosides from the aerial parts of Gouania longipetala.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Enterococcus faecalis; Escherichia coli; Glycosides; HL-60 Cells; Humans; K562 Cells; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Components, Aerial; Rhamnaceae; Saponins; Staphylococcus aureus; Triterpenes | 2017 |
Simultaneous label-free screening of G-quadruplex active ligands from natural medicine via a microfluidic chip electrophoresis-based energy transfer multi-biosensor strategy.
Topics: Aptamers, Nucleotide; Biosensing Techniques; Drug Evaluation, Preclinical; Electrophoresis; Energy Transfer; Fluoresceins; G-Quadruplexes; Graphite; Ligands; Microfluidics; Reproducibility of Results; Saponins | 2017 |
Gastrointestinal Absorption and Metabolic Dynamics of Jujuboside A, A Saponin Derived from the Seed of Ziziphus jujuba.
Topics: Animals; Drugs, Chinese Herbal; Gastrointestinal Absorption; Gastrointestinal Tract; Rats; Rats, Sprague-Dawley; Saponins; Seeds; Ziziphus | 2017 |
[Preparation and identification of Jujuboside A artificial antigen].
Topics: Animals; Antigens; Enzyme-Linked Immunosorbent Assay; Mice; Saponins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Jujuboside A attenuates norepinephrine-induced apoptosis of H9c2 cardiomyocytes by modulating MAPK and AKT signaling pathways.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cell Survival; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Norepinephrine; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Saponins; Signal Transduction | 2018 |
[Investigation of the potentially effective components of Semen Ziziphi Spinosae based on “in vitro to in vivo” translation approach].
Topics: Animals; Apigenin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Mass Spectrometry; Rats; Saponins; Ziziphus | 2017 |
Anti-depressive effect of Shuangxinfang on rats with acute myocardial infarction: Promoting bone marrow mesenchymal stem cells mobilization and alleviating inflammatory response.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Cell Movement; Cells, Cultured; Male; Mesenchymal Stem Cells; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins | 2019 |
Jujuboside A prevents sleep loss-induced disturbance of hippocampal neuronal excitability and memory impairment in young APP/PS1 mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Female; Hippocampus; Male; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Saponins; Sleep Wake Disorders | 2019 |
Detection of synergistic effect of superoxide dismutase and jujubosides on scavenging superoxide anion radical by capillary electrophoresis.
Topics: Anions; Drug Synergism; Electrophoresis, Capillary; Free Radical Scavengers; Linear Models; Pyrogallol; Reproducibility of Results; Saponins; Superoxide Dismutase; Superoxides | 2019 |
Metabolite distribution and correlation studies of Ziziphus jujuba and Ziziphus nummularia using LC-ESI-MS/MS.
Topics: Chromatography, High Pressure Liquid; Correlation of Data; Fruit; Plant Extracts; Plant Leaves; Quercetin; Reproducibility of Results; Saponins; Tandem Mass Spectrometry; Ziziphus | 2020 |
A sensitive two-step stacking by coupling field-enhanced sample injection and micelle to cyclodextrin stacking for the determination of neutral analytes.
Topics: Animals; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Limit of Detection; Micelles; Rats; Saponins | 2020 |
The novel FAT4 activator jujuboside A suppresses NSCLC tumorigenesis by activating HIPPO signaling and inhibiting YAP nuclear translocation.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents, Phytogenic; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Hippo Signaling Pathway; Humans; Lung Neoplasms; Mice; Saponins; Tumor Suppressor Proteins; YAP-Signaling Proteins | 2021 |
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Topics: Animals; Apoptosis; Autophagy; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Kidney; Male; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Saponins; Streptozocin | 2022 |
Jujuboside a promotes proliferation and neuronal differentiation of APPswe-overexpressing neural stem cells by activating Wnt/β-catenin signaling pathway.
Topics: Amyloid beta-Protein Precursor; Animals; Basic Helix-Loop-Helix Transcription Factors; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Female; Heterocyclic Compounds, 3-Ring; Hippocampus; Homeodomain Proteins; Male; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Saponins; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2022 |
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Hippocampus; Humans; Mice; Saponins; Stress, Psychological | 2022 |
Jujuboside A inhibits oxidative stress damage and enhances immunomodulatory capacity of human umbilical cord mesenchymal stem cells through up-regulating IDO expression.
Topics: Animals; Cell Differentiation; Humans; Hydrogen Peroxide; Mesenchymal Stem Cells; Oxidative Stress; Rats; Saponins; Umbilical Cord | 2022 |
Jujuboside A ameliorates tubulointerstitial fibrosis in diabetic mice through down-regulating the YY1/TGF-β1 signaling pathway.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fibrosis; Mice; Saponins; Signal Transduction; Streptozocin; Transforming Growth Factor beta1 | 2022 |
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice.
Topics: Animals; Cognition; Delirium; Hippocampus; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Saponins; Tumor Necrosis Factor-alpha | 2023 |