jtp 4819 has been researched along with kyp 2047 in 5 studies
| Studies (jtp 4819) | Trials (jtp 4819) | Recent Studies (post-2010) (jtp 4819) | Studies (kyp 2047) | Trials (kyp 2047) | Recent Studies (post-2010) (kyp 2047) |
|---|---|---|---|---|---|
| 25 | 1 | 5 | 10 | 0 | 7 |
| Protein | Taxonomy | jtp 4819 (IC50) | kyp 2047 (IC50) |
|---|---|---|---|
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.006 | |
| Prolyl endopeptidase | Sus scrofa (pig) | 0.0018 | |
| Prolyl endopeptidase | Mus musculus (house mouse) | 0.0003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christiaans, JA; Forsberg, MM; Garcia-Horsman, JA; Gynther, J; Huuskonen, J; Jarho, EM; Järvinen, T; Männistö, PT; Venäläinen, JI; Wallén, EA | 1 |
| Christiaans, JA; Forsberg, MM; Gynther, J; Jarho, EM; Männistö, PT; Poso, A; Venäläinen, JI; Wallén, EA | 1 |
| Gerber-Lemaire, S; Juillerat-Jeanneret, L; Lawandi, J; Moitessier, N | 1 |
| Airaghi, F; Auclair, K; De Cesco, S; Huskić, I; Kurian, J; Mariaule, G; Mittermaier, A; Moitessier, N; Rocheleau, S; Schiavini, P | 1 |
| Dufresne, C; Hédou, D; Labarre, A; Mittermaier, A; Moitessier, N; Plescia, J; Pousse, ME | 1 |
1 review(s) available for jtp 4819 and kyp 2047
| Article | Year |
|---|---|
Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.
Topics: Animals; Blood-Brain Barrier; Central Nervous System; Humans; Prolyl Oligopeptidases; Protein Binding; Serine Endopeptidases; Serine Proteinase Inhibitors | 2010 |
4 other study(ies) available for jtp 4819 and kyp 2047
| Article | Year |
|---|---|
A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.
Topics: 1-Octanol; Animals; Brain; Buffers; Cyclopentanes; In Vitro Techniques; Molecular Mimicry; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Solubility; Structure-Activity Relationship; Swine | 2004 |
Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.
Topics: Amides; Animals; Aza Compounds; Brain; Dicarboxylic Acids; In Vitro Techniques; Models, Molecular; Proline; Prolyl Oligopeptidases; Pyrrolidines; Quantitative Structure-Activity Relationship; Serine Endopeptidases; Serine Proteinase Inhibitors; Swine | 2005 |
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.
Topics: Bridged Bicyclo Compounds; Carboxylic Acids; Humans; Isoindoles; Molecular Docking Simulation; Molecular Structure; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Stereoisomerism | 2016 |
Modulating the selectivity of inhibitors for prolyl oligopeptidase inhibitors and fibroblast activation protein-α for different indications.
Topics: Endopeptidases; Enzyme Inhibitors; Humans; Membrane Proteins; Neoplasms; Prolyl Oligopeptidases; Serine Endopeptidases | 2022 |