Page last updated: 2024-09-04

jte 522 and fluorouracil

jte 522 has been researched along with fluorouracil in 3 studies

Compound Research Comparison

Studies
(jte 522)
Trials
(jte 522)
Recent Studies (post-2010)
(jte 522)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
611745,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomyjte 522 (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirose, F; Ikeda, Y; Nakamura, Y; Nishimura, G; Satake, K; Taguchi, T; Tsukuda, M; Yanoma, S1
Kamoi, K; Kawauchi, A; Miki, T; Mizutani, Y; Ukimura, O1
Hirakawa, K; Nakazawa, K; Tendo, M; Yamada, N; Yashiro, M1

Other Studies

3 other study(ies) available for jte 522 and fluorouracil

ArticleYear
An experimental model of tumor dormancy therapy for advanced head and neck carcinoma.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Biotransformation; Cell Division; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Combinations; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Organic Chemicals; Oxonic Acid; Probucol; Prodrugs; Prostaglandin-Endoperoxide Synthases; Pyridines; Tegafur; Telomerase; Xenograft Model Antitumor Assays

2000
Synergistic cytotoxicity and apoptosis of JTE-522, a selective cyclooxygenase-2 inhibitor, and 5-fluorouracil against bladder cancer.
    The Journal of urology, 2002, Volume: 168, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Benzenesulfonates; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Fluorouracil; Humans; Isoenzymes; Male; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2002
Inhibitory effect of a selective cyclooxygenase inhibitor on the invasion-stimulating activity of orthotopic fibroblasts for scirrhous gastric cancer cells.
    Cancer science, 2005, Volume: 96, Issue:7

    Topics: Adenocarcinoma, Scirrhous; Animals; Antineoplastic Agents; Benzenesulfonates; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Fibroblasts; Fluorouracil; Hepatocyte Growth Factor; Humans; In Vitro Techniques; Mice; Mice, Nude; Oxazoles; Prostaglandins E; Stomach Neoplasms

2005