jte 522 has been researched along with dinoprostone in 14 studies
| Studies (jte 522) | Trials (jte 522) | Recent Studies (post-2010) (jte 522) | Studies (dinoprostone) | Trials (dinoprostone) | Recent Studies (post-2010) (dinoprostone) |
|---|---|---|---|---|---|
| 61 | 1 | 7 | 29,105 | 1,346 | 6,357 |
| Protein | Taxonomy | jte 522 (IC50) | dinoprostone (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | 0.0155 | |
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0031 | |
| Prostaglandin E2 receptor EP4 subtype | Rattus norvegicus (Norway rat) | 0.0021 | |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | 0.002 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.0087 | |
| Prostacyclin receptor | Homo sapiens (human) | 0.26 | |
| Prostaglandin E2 receptor EP2 subtype | Rattus norvegicus (Norway rat) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 12 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mue, S; Niki, H; Ohuchi, K; Yamada, M; Yamaki, K | 1 |
| Masaki, M; Matsushita, M; Nanayama, T; Wakitani, K | 1 |
| Iwamura, H; Matsushita, M; Tazaki, H; Wakitani, K | 1 |
| Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Matsumoto, K; Nakano, H | 1 |
| Ding, Y; Hong, T; Imamura, M; Kaganoi, J; Kawabe, A; Komoto, I; Li, Z; Maeda, M; Sato, F; Shimada, Y | 1 |
| Dubois, RN; Kobayashi, O; Miwa, H; Sato, N; Tsujii, M; Watanabe, S | 1 |
| Harada, M; Hayakawa, T; Ito, T; Matsui, H; Naruse, K; Numaguchi, Y; Okumura, K; Yamada, M | 1 |
| Hirose, M; Kobayashi, O; Kurosawa, A; Misawa, H; Miwa, H; Oshida, K; Sato, N; Watanabe, S | 1 |
| Hirakawa, K; Nagatsuka, I; Nishino, H; Ohira, M; Seki, S; Shimizu, S; Yamada, N | 1 |
| Imamura, M; Itami, A; Kaganoi, J; Kawabe, A; Kiyono, T; Maeda, M; Shimada, Y; Soma, T | 1 |
| Asakage, M; Hori, N; Kaisaki, S; Kawai, K; Kitayama, J; Nagawa, H; Okaji, Y; Sunami, E; Takahashi, K; Tsuno, NH; Watanabe, T; Yazawa, K | 1 |
| Inoue, H; Kuge, Y; Minematsu, K; Tamaki, N; Yokota, C | 1 |
| Hirakawa, K; Kosaka, K; Nakazawa, K; Shinto, O; Tendo, M; Yashiro, M | 1 |
| Murawaki, Y; Nagahara, T; Okano, J | 1 |
14 other study(ies) available for jte 522 and dinoprostone
| Article | Year |
|---|---|
Effects of JTE-522, a specific inhibitor of cyclooxygenase-2, on the recurrence of allergic inflammation in rats.
Topics: Animals; Benzenesulfonates; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Hypersensitivity; Isoenzymes; Macrophages, Peritoneal; Male; Oxazoles; Peroxidases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley | 1998 |
Profile of JTE-522 as a human cyclooxygenase-2 inhibitor.
Topics: Benzenesulfonates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Isoenzymes; Leukocytes, Mononuclear; Lipopolysaccharides; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Time Factors | 1998 |
JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues.
Topics: Animals; Benzenesulfonates; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Foot; Gastric Mucosa; Inflammation; Isoenzymes; Macrophages, Peritoneal; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 2000 |
Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Benzenesulfonates; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Histamine; Immunohistochemistry; Isoenzymes; Male; Oxazoles; Oxidants, Photochemical; Ozone; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2 | 2000 |
Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by JTE-522, a selective COX-2 inhibitor.
Topics: Animals; Benzenesulfonates; Body Weight; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethylnitrosamine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells.
Topics: Animals; Arachidonic Acid; Benzenesulfonates; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA-Binding Proteins; Down-Regulation; Enzyme Induction; Epithelial Cells; I-kappa B Proteins; Interferon Regulatory Factor-1; Interferon-gamma; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazoles; Phosphoproteins; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Transcription Factor AP-1; Transfection | 2001 |
Prostacyclin synthase gene transfer modulates cyclooxygenase-2-derived prostanoid synthesis and inhibits neointimal formation in rat balloon-injured arteries.
Topics: Angioplasty, Balloon; Animals; Benzenesulfonates; Carotid Arteries; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Dinoprostone; Gene Transfer Techniques; Genetic Therapy; Immunohistochemistry; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Male; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; Tunica Intima | 2002 |
Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway.
Topics: Animals; Arachidonic Acid; Benzenesulfonates; Cell Division; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epithelial Cells; Gastric Mucosa; Isoenzymes; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Wound Healing | 2002 |
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
Topics: Animals; Benzenesulfonates; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Humans; Isoenzymes; Liver Neoplasms; Lymphokines; Matrix Metalloproteinases; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Oxazoles; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells.
Topics: Benzenesulfonates; Cell Survival; Cells, Cultured; Chenodeoxycholic Acid; Culture Media; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Duodenogastric Reflux; Epithelial Cells; Esophagus; Humans; Hydrogen-Ion Concentration; Immunoblotting; Isoenzymes; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Trypsin; Up-Regulation | 2004 |
Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.
Topics: Benzenesulfonates; Cell Adhesion; Cell Division; Cell Movement; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Matrix; HT29 Cells; Humans; Integrin beta1; Membrane Proteins; Oxazoles; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured | 2005 |
Bilateral induction of the S-100A9 gene in response to spreading depression is modulated by the cyclooxygenase-2 activity.
Topics: Animals; Benzenesulfonates; Brain; Cortical Spreading Depression; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Functional Laterality; Gene Expression; Male; Mitogen-Activated Protein Kinases; Oligonucleotide Array Sequence Analysis; Oxazoles; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S100 Proteins | 2005 |
Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma.
Topics: Animals; Benzenesulfonates; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Female; Fibroblast Growth Factor 7; Fibroblasts; Humans; Immunoblotting; Immunohistochemistry; Mesoderm; Mice; Mice, Inbred BALB C; Mice, Nude; Oxazoles; Paracrine Communication; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2007 |
Mechanisms of anti-proliferative effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on human liver cancer cells.
Topics: Apoptosis; Benzenesulfonates; Carcinoma, Hepatocellular; Caspases; Cell Proliferation; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; Oncogene Proteins; Oxazoles; PPAR gamma; Tumor Cells, Cultured | 2007 |