Compounds > jolkinolide b
Page last updated: 2024-09-03

jolkinolide b and indomethacin

jolkinolide b has been researched along with indomethacin in 2 studies

Compound Research Comparison

Studies
(jolkinolide b)		Trials
(jolkinolide b)		Recent Studies (post-2010)
(jolkinolide b)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
3502729,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyjolkinolide b (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bai, J; Hua, HM; Li, DH; Li, N; Li, ZL; Liu, ZG; Meng, DL; Zhao, F1
Han, SB; Hong, JT; Hwang, BY; Jang, H; Jin, Q; Kim, Y; Lee, C; Lee, D; Lee, HJ; Lee, JW; Lee, MK; Shin, JW1

Other Studies

2 other study(ies) available for jolkinolide b and indomethacin

ArticleYear
ent-Abietane-type diterpenoids from the roots of Euphorbia ebracteolata with their inhibitory activities on LPS-induced NO production in RAW 264.7 macrophages.
    Bioorganic & medicinal chemistry letters, 2016, Jan-01, Volume: 26, Issue:1

    Topics: Abietanes; Animals; Dose-Response Relationship, Drug; Euphorbia; Lipopolysaccharides; Macrophages; Mice; Molecular Conformation; Nitric Oxide; Plant Roots; Structure-Activity Relationship

2016
Diterpenoids from the Roots of Euphorbia fischeriana with Inhibitory Effects on Nitric Oxide Production.
    Journal of natural products, 2016, Jan-22, Volume: 79, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; Diterpenes; Drugs, Chinese Herbal; Euphorbia; Lipopolysaccharides; Macrophages; Mice; Molecular Conformation; Molecular Structure; Nitric Oxide; Plant Roots; Republic of Korea

2016