jmv 449 has been researched along with neurotensin in 11 studies
| Studies (jmv 449) | Trials (jmv 449) | Recent Studies (post-2010) (jmv 449) | Studies (neurotensin) | Trials (neurotensin) | Recent Studies (post-2010) (neurotensin) |
|---|---|---|---|---|---|
| 15 | 0 | 5 | 4,054 | 45 | 544 |
| Protein | Taxonomy | jmv 449 (IC50) | neurotensin (IC50) |
|---|---|---|---|
| Neurotensin receptor type 1 | Homo sapiens (human) | 0.0013 | |
| Neurotensin receptor type 2 | Rattus norvegicus (Norway rat) | 0.0582 | |
| Sortilin | Homo sapiens (human) | 0.36 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Forgez, P; Hermans, E; Lebeau, A; Lhiaubet, AM; Pelaprat, D; Rostene, W; Skrzydelski, D; Yamada, M | 1 |
| Costentin, J; Doulut, S; Dubuc, I; Kitabgi, P; Martinez, J; Rodriguez, M | 1 |
| Bourdel, E; Brotchi, J; Camby, I; Danguy, A; Kiss, R; Martinez, J; Nagy, N; Pasteels, JL; Salmon, I | 1 |
| Forgez, P; Rostène, W; Souazé, F | 1 |
| Forgez, P; Lombet, A; Rostène, W; Yamada, M | 1 |
| Forgez, P; Hermans, E; Najimi, M; Rostène, W | 1 |
| Forgez, P; Mallet, J; Najimi, M; Robert, JJ; Rostène, W | 1 |
| Borsdal, J; Sager, T; Torup, L | 1 |
| Hugel, S; Kadiri, N; Rodeau, JL; Schlichter, R | 1 |
| Männistö, PT; Myöhänen, TT; Peltonen, I | 1 |
| Craig, SL; Gault, VA; Hamscher, G; Irwin, N; Shiels, CE | 1 |
11 other study(ies) available for jmv 449 and neurotensin
| Article | Year |
|---|---|
Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.
Topics: Animals; Arachidonic Acid; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Oligopeptides; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Rats; Receptors, Neurotensin; Tritium | 2003 |
JMV 449: a pseudopeptide analogue of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse.
Topics: Amino Acid Sequence; Analgesics; Animals; Guinea Pigs; Hypothermia; Male; Mice; Molecular Sequence Data; Neurotensin; Oligopeptides | 1992 |
Neurotensin-mediated effects on astrocytic tumor cell proliferation.
Topics: Astrocytoma; Cell Division; Colorimetry; Glioblastoma; Humans; Neurotensin; Oligopeptides; Protease Inhibitors; Tumor Cells, Cultured | 1996 |
Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms.
Topics: Analgesics; Humans; Neurotensin; Oligopeptides; Protein Processing, Post-Translational; Pyrazoles; Quinolines; Receptors, Neurotensin; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Distinct functional characteristics of levocabastine sensitive rat neurotensin NT2 receptor expressed in Chinese hamster ovary cells.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Neurotensin; Oligopeptides; Piperidines; Pyrazoles; Quinolines; Rats; Receptors, Neurotensin; Signal Transduction; Transfection | 1998 |
Transcriptional regulation of the tyrosine hydroxylase gene by neurotensin in human neuroblastoma CHP212 cells.
Topics: Blotting, Western; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Neuroblastoma; Neurotensin; Oligopeptides; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2001 |
Neurotensin induces tyrosine hydroxylase gene activation through nitric oxide and protein kinase C signaling pathways.
Topics: Animals; Gene Expression Regulation; Mice; Neurotensin; Nitric Oxide; Oligopeptides; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2002 |
Neuroprotective effect of the neurotensin analogue JMV-449 in a mouse model of permanent middle cerebral ischaemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Neurotensin; Oligopeptides | 2003 |
Neurotensin inhibits background K+ channels and facilitates glutamatergic transmission in rat spinal cord dorsal horn.
Topics: Animals; Benzophenanthridines; Excitatory Postsynaptic Potentials; Glutamic Acid; Neurotensin; Oligopeptides; Patch-Clamp Techniques; Pertussis Toxin; Piperidines; Posterior Horn Cells; Potassium Channels; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Signal Transduction; Synapses; Synaptic Transmission | 2011 |
Different interactions of prolyl oligopeptidase and neurotensin in dopaminergic function of the rat nigrostriatal and mesolimbic pathways.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Enzyme Inhibitors; Injections, Intraventricular; Limbic System; Male; Microscopy, Confocal; Microscopy, Fluorescence; Neural Pathways; Neurotensin; Oligopeptides; Prolyl Oligopeptidases; Pyrazoles; Quinolines; Rats; Rats, Wistar; Receptors, Neurotensin; Serine Endopeptidases; Stereotaxic Techniques; Substantia Nigra; Ventral Tegmental Area | 2012 |
Comparison of independent and combined effects of the neurotensin receptor agonist, JMV-449, and incretin mimetics on pancreatic islet function, glucose homeostasis and appetite control.
Topics: Animals; Appetite; Blood Glucose; Homeostasis; Incretins; Insulin Secretion; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Neurotensin; Oligopeptides; Receptors, Neurotensin | 2021 |