jl 18 and clozapine

jl 18 has been researched along with clozapine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruhwyler, J; Chleide, EM; Damas, J; Delarge, JE; Liégeois, JF; Mercier, MG; Nguyen, TP; Rogister, FA1
Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW; TenBrink, RE1
Bruhwyler, J; Carato, P; Damas, J; Delarge, J; Ellenbroek, BA; Eyrolles, L; Géczy, J; Lejeune, C; Liégeois, JF1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Bruhwyler, J; Damas, J; Delarge, J; Geczy, J; Liégeois, JF; Masereel, B; Rogister, F1
Bangassoro, E; Bédard, PJ; Bélanger, N; Grégoire, L; Hadj Tahar, A1
Katsuragi, T; Kita, S; Morishita, H; Sakata, N; Shibata, K1

Other Studies

8 other study(ies) available for jl 18 and clozapine

ArticleYear
New pyridobenzodiazepine derivatives as potential antipsychotics: synthesis and neurochemical study.
    Journal of medicinal chemistry, 1993, Jul-23, Volume: 36, Issue:15

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding Sites; Dogs; Rats; Structure-Activity Relationship

1993
(S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Animals; Antipsychotic Agents; Biological Availability; CHO Cells; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ergolines; Humans; Molecular Structure; Piperazines; Protein Binding; Quinpirole; Receptors, Adrenergic; Receptors, Dopamine D4; Receptors, Serotonin; Schizophrenia; Sulfonamides

1996
New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors.
    Journal of medicinal chemistry, 2002, Nov-07, Volume: 45, Issue:23

    Topics: Amines; Animals; Antidepressive Agents; Benzodiazepines; Catalepsy; Cell Line; Dopamine Agents; Female; Humans; Mice; Molecular Conformation; Piperazines; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Serotonin; Serotonin Agents; Structure-Activity Relationship

2002
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Modulation of the clozapine structure increases its selectivity for the dopamine D4 receptor.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Apomorphine; Binding, Competitive; Cells, Cultured; Clozapine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Spiperone; Structure-Activity Relationship

1995
Antidyskinetic effect of JL-18, a clozapine analog, in parkinsonian monkeys.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Benserazide; Clozapine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Activity; Parkinsonian Disorders

2000
A new approach to finding specific dopamine D4 receptor agonists.
    European journal of pharmacology, 2005, Jun-01, Volume: 516, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Apomorphine; Blotting, Western; Bromocriptine; Cloning, Molecular; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Phenethylamines; Prazosin; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Vas Deferens

2005