jk184 and pyridine

jk184 has been researched along with pyridine* in 1 studies

Other Studies

1 other study(ies) available for jk184 and pyridine

Article	Year
The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:13 Eradicating hedgehogs: The title molecule has been previously identified as a potent inhibitor of the Hedgehog signaling pathway, which gives embryonic cells information needed to develop properly. This molecule is shown to modulate Hedgehog target gene expression by depolymerizing microtubules, thus revealing dual roles of the cytoskeleton in pathway regulation (see figure). Topics: Animals; Cell Line; Gene Expression Regulation, Developmental; Hedgehog Proteins; Heterocyclic Compounds, 2-Ring; Mice; Microtubules; NIH 3T3 Cells; Pyridines; Signal Transduction; Thiazoles	2009

Article

Year

The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling.

Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:13

Eradicating hedgehogs: The title molecule has been previously identified as a potent inhibitor of the Hedgehog signaling pathway, which gives embryonic cells information needed to develop properly. This molecule is shown to modulate Hedgehog target gene expression by depolymerizing microtubules, thus revealing dual roles of the cytoskeleton in pathway regulation (see figure).

Topics: Animals; Cell Line; Gene Expression Regulation, Developmental; Hedgehog Proteins; Heterocyclic Compounds, 2-Ring; Mice; Microtubules; NIH 3T3 Cells; Pyridines; Signal Transduction; Thiazoles

2009