jervine has been researched along with cyclopamine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, N; Mahindroo, N; Punchihewa, C | 1 |
| Giannis, A; Heretsch, P; Tzagkaroulaki, L | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Keeler, RF | 1 |
| Beachy, PA; Cooper, MK; Porter, JA; Young, KE | 1 |
| Helms, JA; Hu, D; Schneider, RA; Young, DL | 1 |
| Beachy, PA; Mann, RK | 1 |
| Gaffield, W; Lee, ST; Panter, KE; Stegelmeier, BL | 1 |
| Gaffield, W; Liu, HX; MacCallum, DK; Mistretta, CM | 1 |
| Edwards, C; Gaffield, W; Liu, HX; Maccallum, DK; Mistretta, CM | 1 |
| Fujita, T; Koshima, I; Nagase, M; Nagase, T | 1 |
| Chen, MH; Chuang, PT; Wilson, CW | 1 |
| Giannis, A; Heretsch, P; Rabe, S | 1 |
| Aran, JM; Balbuena, J; Castresana, JS; Lopez-Torrents, G; Pachon, G; Petriz, J | 1 |
| Beneytout, JL; Cook-Moreau, J; Ghezali, L; Leger, DY; Liagre, B; Limami, Y | 1 |
| Kazuma, K; Konno, K | 1 |
| Altmeyer, R; Bailly, B; Cao, J; Cui, R; Eléouët, JF; Galloux, M; Guillon, P; Johansen, L; Pendharkar, V; Richard, CA; Sharma, DC; Sharma, G; von Itzstein, M; Wang, L; Wang, Y; Zou, G | 1 |
| Lin, X; Liu, M; Lu, X; Zhang, J; Zhang, W; Zhao, X | 1 |
5 review(s) available for jervine and cyclopamine
| Article | Year |
|---|---|
Hedgehog-Gli signaling pathway inhibitors as anticancer agents.
Topics: Antineoplastic Agents; Drug Discovery; Hedgehog Proteins; Humans; Neoplasms; Signal Transduction; Transcription Factors; Zinc Finger Protein GLI1 | 2009 |
Modulators of the hedgehog signaling pathway.
Topics: Antineoplastic Agents; Hedgehog Proteins; Humans; Neoplasms; Signal Transduction; Veratrum Alkaloids | 2010 |
Genetic and teratogenic approaches to craniofacial development.
Topics: Animals; Chick Embryo; Cleft Lip; Cleft Palate; Cytoskeletal Proteins; DNA-Binding Proteins; Embryonic and Fetal Development; Embryonic Induction; Gene Expression Regulation, Developmental; Genes, Homeobox; Hedgehog Proteins; Homeodomain Proteins; Maxillofacial Development; Mice; Proteins; Retinoids; RNA-Binding Proteins; Skull; Teratogens; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Veratrum Alkaloids | 2000 |
Cholesterol modification of proteins.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cholesterol; Drosophila; Embryonic Induction; Endodeoxyribonucleases; Hedgehog Proteins; Membrane Glycoproteins; Models, Chemical; Molecular Sequence Data; Nematoda; Proteins; Proton-Translocating ATPases; Saccharomyces cerevisiae Proteins; Signal Transduction; Teratogens; Trans-Activators; Veratrum Alkaloids | 2000 |
[Poisoning by accidental ingestion of poisonous plants].
Topics: Accidents; Aconitine; Aconitum; Cicuta; Conium; Humans; Japan; Plant Poisoning; Plants, Toxic; Scopolia; Veratrum; Veratrum Alkaloids | 2013 |
13 other study(ies) available for jervine and cyclopamine
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Teratogenic effects of cyclopamine and jervine in rats, mice and hamsters.
Topics: Animals; Brain; Cleft Lip; Cricetinae; Female; Furans; Gestational Age; Mice; Microphthalmos; Piperidines; Pregnancy; Rats; Teratogens; Veratrum Alkaloids | 1975 |
Teratogen-mediated inhibition of target tissue response to Shh signaling.
Topics: Abnormalities, Drug-Induced; Animals; Cell Membrane; Central Nervous System; Chick Embryo; Cholesterol; Culture Techniques; DNA-Binding Proteins; Endoplasmic Reticulum; Hedgehog Proteins; Hepatocyte Nuclear Factor 3-beta; Holoprosencephaly; Homeodomain Proteins; LIM-Homeodomain Proteins; Membrane Proteins; Muscle Proteins; Nerve Tissue Proteins; Nuclear Proteins; Patched Receptors; PAX7 Transcription Factor; Proteins; Receptors, Cell Surface; Signal Transduction; Teratogens; Tomatine; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Trans-Activators; Transcription Factors; Triparanol; Veratrum Alkaloids | 1998 |
Development of an enzyme-linked immunosorbent assay for the veratrum plant teratogens: cyclopamine and jervine.
Topics: Abnormalities, Drug-Induced; Animals; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Immune Sera; Sheep; Sheep Diseases; Teratogens; Veratrum; Veratrum Alkaloids | 2003 |
Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number and form in novel locations in dorsal lingual epithelium.
Topics: Animals; Body Patterning; Epithelium; Female; Hedgehog Proteins; Immunohistochemistry; Microscopy, Electron, Scanning; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Taste Buds; Tongue; Trans-Activators; Veratrum Alkaloids | 2003 |
Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development.
Topics: Animals; Embryo, Mammalian; Female; Gestational Age; Hedgehog Proteins; Mandible; Membrane Proteins; Microscopy, Electron, Scanning; Morphogenesis; Patched Receptors; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Signal Transduction; Taste Buds; Tissue Culture Techniques; Tongue; Trans-Activators; Veratrum Alkaloids | 2004 |
Critical time window of hedgehog-dependent angiogenesis in murine yolk sac.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Culture Media; Embryo, Mammalian; Gene Expression; Hedgehog Proteins; Immunohistochemistry; In Situ Hybridization; Mice; Neovascularization, Physiologic; Organ Culture Techniques; Receptor, TIE-2; Time Factors; Trans-Activators; Veratrum Alkaloids; Yolk Sac | 2006 |
Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.
Topics: Animals; Cells, Cultured; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fibroblasts; GTP-Binding Protein alpha Subunits, Gs; Hedgehog Proteins; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; Piperazines; Protein Conformation; Protein Transport; Pyrazoles; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Veratrum Alkaloids | 2009 |
Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine.
Topics: Biological Products; Catalysis; Molecular Structure; Piperidines; Stereoisomerism; Veratrum Alkaloids | 2009 |
ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Blotting, Western; Carbazoles; Flow Cytometry; Hedgehog Proteins; Humans; Hydroxycholesterols; Indole Alkaloids; KB Cells; Mitoxantrone; Neoplasm Proteins; Patched Receptors; Receptors, Cell Surface; Side-Population Cells; Signal Transduction; Transfection; Veratrum Alkaloids | 2011 |
Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Humans; Leukemia, Erythroblastic, Acute; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Veratrum Alkaloids | 2013 |
Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication.
Topics: Alkaloids; Animals; Cell Line; Disease Models, Animal; DNA-Directed RNA Polymerases; Drug Resistance, Viral; Female; Gene Expression Regulation, Viral; Humans; Mice, Inbred BALB C; Models, Molecular; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Smoothened Receptor; Transcription, Genetic; Veratrum; Veratrum Alkaloids; Viral Proteins; Virus Replication | 2016 |
Teratogenic jervine increases the activity of doxorubicin in MCF-7/ADR cells by inhibiting ABCB1.
Topics: ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; Protein Structure, Secondary; Substrate Specificity; Teratogens; Veratrum Alkaloids | 2019 |