jadomycin-a and 4-aminophenylalanine

jadomycin-a has been researched along with 4-aminophenylalanine* in 1 studies

Other Studies

1 other study(ies) available for jadomycin-a and 4-aminophenylalanine

ArticleYear
Isolation and Synthetic Diversification of Jadomycin 4-Amino-l-phenylalanine.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Streptomyces venezuelae ISP5230 was grown in the presence of phenylalanine analogues to observe whether they could be incorporated into novel jadomycin structures. It was found that the bacteria successfully produced jadomycins incorporating 4-aminophenylalanine enantiomers. Upon isolation and characterization of jadomycin 4-amino-l-phenylalanine (1), it was synthetically derivatized, using activated succinimidyl esters, to yield a small jadomycin amide library. These are the first examples of oxazolone-ring-containing jadomycins that have incorporated an amino functionality subsequently used for derivatization.

    Topics: Isoquinolines; Molecular Structure; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Oxazolone; Phenylalanine; Streptomyces

2015