Compounds > ivabradine
Page last updated: 2024-09-04

ivabradine and verapamil

ivabradine has been researched along with verapamil in 4 studies

Compound Research Comparison

Studies
(ivabradine)		Trials
(ivabradine)		Recent Studies (post-2010)
(ivabradine)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
1,14319783317,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyivabradine (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Camm, AJ; Yusuf, S1
Boldt, A; Gergs, U; Neumann, J; Pönicke, K; Silber, RE; Simm, A1
Drożdż, J; Filipiak, KJ; Grajek, S; Kasprzak, JD; Opolski, G; Rynkiewicz, A; Stępińska, J; Tykarski, A; Wożakowska Kapłon, B1
Chang, S; Lu, S; Shen, L; Tong, X; Wang, Y; Zhou, X1

Reviews

2 review(s) available for ivabradine and verapamil

ArticleYear
Sinus tachyarrhythmias and the specific bradycardic agents: a marriage made in heaven?
    Journal of cardiovascular pharmacology and therapeutics, 2003, Volume: 8, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Benzazepines; Calcium Channel Blockers; Clonidine; Diagnosis, Differential; Humans; Isoindoles; Ivabradine; Phthalimides; Pyrimidines; Sinoatrial Node; Tachycardia, Sinus; Vasodilator Agents; Verapamil

2003
Comparative Efficacy of Different Drugs for the Treatment of Dilated Cardiomyopathy: A Systematic Review and Network Meta-analysis.
    Drugs in R&D, 2023, Volume: 23, Issue:3

    Topics: Cardiomyopathy, Dilated; Carvedilol; Humans; Ivabradine; Network Meta-Analysis; Randomized Controlled Trials as Topic; Stroke Volume; Trimetazidine; Ventricular Function, Left; Verapamil

2023

Other Studies

2 other study(ies) available for ivabradine and verapamil

ArticleYear
Inotropic effects of ivabradine in the mammalian heart.
    Pharmacology, 2010, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Benzazepines; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Atria; Humans; Ivabradine; Male; Mice; Middle Aged; Myocardial Contraction; Piperidines; Species Specificity; Verapamil

2010
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
    Kardiologia polska, 2012, Volume: 70, Issue:10

    Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Digoxin; Diltiazem; Heart Diseases; Heart Rate; Humans; Hypertension; Ivabradine; Verapamil

2012