ivabradine has been researched along with spironolactone in 9 studies
| Studies (ivabradine) | Trials (ivabradine) | Recent Studies (post-2010) (ivabradine) | Studies (spironolactone) | Trials (spironolactone) | Recent Studies (post-2010) (spironolactone) |
|---|---|---|---|---|---|
| 1,143 | 197 | 833 | 7,222 | 960 | 1,923 |
| Protein | Taxonomy | ivabradine (IC50) | spironolactone (IC50) |
|---|---|---|---|
| Chain A, Mineralocorticoid receptor | Homo sapiens (human) | 0.049 | |
| Chain A, Mineralocorticoid receptor | Homo sapiens (human) | 0.049 | |
| Estrogen receptor | Homo sapiens (human) | 5.702 | |
| Glucocorticoid receptor | Homo sapiens (human) | 4.0745 | |
| Progesterone receptor | Homo sapiens (human) | 1.675 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 1.9025 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0315 | |
| Androgen receptor | Homo sapiens (human) | 0.3585 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.406 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 1.9025 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 1.9025 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 1.9025 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 6.92 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akchurin, RS; Chernova, NA; Erastova, NV; Grishin, IR; Karpov, IuA; Latypov, RS; Lopukhova, VV; Mareev, IuV; Saidova, MA; Sapel'nikov, OV | 1 |
| Ertl, G; Merx, MW | 1 |
| Alabd, A; Gamal, A; Rayan, M; Tawfik, M | 1 |
| Taylor, J | 1 |
| Cowie, MR | 1 |
| Sayer, GT; Tannenbaum, S | 1 |
| Gómez Casal, V; Lage Cendon, L; Lago Preciado, G; Vara Adrio, S | 1 |
| Kanorskiy, SG; Pokrovskiy, VM; Tregubov, VG | 1 |
| Brugts, JJ; Brunner-La Rocca, HP; Hoes, AW; Linssen, GC; Rademaker, PC; Schaafsma, HJ; Smeele, FJ; van de Kamp, HJ; van Drimmelen, AA; Westendorp, PH | 1 |
2 review(s) available for ivabradine and spironolactone
| Article | Year |
|---|---|
[Heart failure].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Benzazepines; Cardiac Resynchronization Therapy; Combined Modality Therapy; Cyclic Nucleotide-Gated Cation Channels; Eplerenone; Heart Failure; Heart Rate; Hemodynamics; Humans; Ivabradine; Mineralocorticoid Receptor Antagonists; Spironolactone; Stroke Volume; Survival Rate | 2011 |
Advances in the pathophysiology and treatment of heart failure with preserved ejection fraction.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiovascular Agents; Heart Failure; Humans; Ivabradine; Mineralocorticoid Receptor Antagonists; Phosphodiesterase 5 Inhibitors; Renin-Angiotensin System; Spironolactone; Stroke Volume; Water-Electrolyte Imbalance | 2015 |
1 trial(s) available for ivabradine and spironolactone
| Article | Year |
|---|---|
Ivabradine, a novel heart rate slower: is it a sword of double blades in patients with idiopathic dilated cardiomyopathy?
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzazepines; Carbazoles; Cardiomyopathy, Dilated; Cardiotonic Agents; Carvedilol; Digoxin; Diuretics; Drug Therapy, Combination; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Propanolamines; Prospective Studies; Spironolactone; Vasodilator Agents; Ventricular Premature Complexes | 2011 |
6 other study(ies) available for ivabradine and spironolactone
| Article | Year |
|---|---|
[Application of cardiac resynchronization therapy and ivabradine in a patient with chronic heart failure].
Topics: Benzazepines; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiovascular Agents; Digoxin; Diuretics; Echocardiography; Electrocardiography; Furosemide; Heart Atria; Heart Failure; Heart Rate; Heart Ventricles; Humans; Ivabradine; Male; Middle Aged; Myocardial Infarction; Spironolactone; Treatment Outcome | 2010 |
The 2012 ESC Guidelines on Heart Failure.
Topics: Benzazepines; Cardiac Resynchronization Therapy; Cardiotonic Agents; Eplerenone; Europe; Heart Failure; Humans; Infusions, Intravenous; Iron; Ivabradine; Life Style; Mineralocorticoid Receptor Antagonists; Practice Guidelines as Topic; Societies, Medical; Spironolactone | 2012 |
Recent developments in the management of heart failure.
Topics: Algorithms; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Eplerenone; Heart Failure; Humans; Ivabradine; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Patient Care Team; Peptide Fragments; Spironolactone; Ventricular Dysfunction, Left | 2012 |
[Ivabradine poisoning with suicide intention].
Topics: Adult; Antidotes; Benzazepines; Bradycardia; Calcium Gluconate; Combined Modality Therapy; Drug Overdose; Electrocardiography; Female; Humans; Ivabradine; Loperamide; Losartan; Norepinephrine; Pacemaker, Artificial; Poisoning; Spironolactone; Suicide, Attempted | 2015 |
[Regulatory Adaptive Status in Assessment of Efficacy of Pharmacotherapy and Prognostication of Complications in Functional Class III Chronic Heart Failure].
Topics: Aged; Benzazepines; Cardiovascular Agents; Chronic Disease; Echocardiography; Exercise Test; Female; Heart Failure; Humans; Hypertension; Ivabradine; Male; Metoprolol; Middle Aged; Quinapril; Random Allocation; Spironolactone; Tetrahydroisoquinolines; Treatment Outcome; Ventricular Function, Left | 2016 |
Contemporary Drug Treatment of Chronic Heart Failure With Reduced Ejection Fraction: The CHECK-HF Registry.
Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Agents; Chronic Disease; Cross-Sectional Studies; Female; Furosemide; Guideline Adherence; Heart Failure; Humans; Ivabradine; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Netherlands; Practice Guidelines as Topic; Registries; Renin-Angiotensin System; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone; Stroke Volume | 2019 |