Compounds > ivabradine
Page last updated: 2024-09-04

ivabradine and diltiazem

ivabradine has been researched along with diltiazem in 3 studies

Compound Research Comparison

Studies
(ivabradine)		Trials
(ivabradine)		Recent Studies (post-2010)
(ivabradine)		Studies
(diltiazem)		Trials
(diltiazem)		Recent Studies (post-2010) (diltiazem)
1,1431978336,4021,073578

Protein Interaction Comparison

ProteinTaxonomyivabradine (IC50)diltiazem (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.45
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.605
Cytochrome P450 3A4Homo sapiens (human)1.8366
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.896
Sodium channel protein type 1 subunit alphaHomo sapiens (human)9
Sodium channel protein type 4 subunit alphaHomo sapiens (human)9
Sodium channel protein type 7 subunit alphaHomo sapiens (human)9
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.605
Sodium channel protein type 5 subunit alphaHomo sapiens (human)9
Sodium channel protein type 9 subunit alphaHomo sapiens (human)9
Sodium channel protein type 2 subunit alphaHomo sapiens (human)9
Sodium channel protein type 3 subunit alphaHomo sapiens (human)9
Sodium channel protein type 11 subunit alphaHomo sapiens (human)9
Sodium channel protein type 8 subunit alphaHomo sapiens (human)9
Sodium channel protein type 10 subunit alphaHomo sapiens (human)9

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drożdż, J; Filipiak, KJ; Grajek, S; Kasprzak, JD; Opolski, G; Rynkiewicz, A; Stępińska, J; Tykarski, A; Wożakowska Kapłon, B1
Belardinelli, L; Machado, AD; Nearing, BD; Sobrado, LF; Varone, BB; Verrier, RL; Zeng, D1
Mittal, SR1

Other Studies

3 other study(ies) available for ivabradine and diltiazem

ArticleYear
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
    Kardiologia polska, 2012, Volume: 70, Issue:10

    Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Digoxin; Diltiazem; Heart Diseases; Heart Rate; Humans; Hypertension; Ivabradine; Verapamil

2012
Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect.
    Journal of cardiovascular electrophysiology, 2013, Volume: 24, Issue:8

    Topics: Amiodarone; Analysis of Variance; Animals; Arterial Pressure; Benzazepines; Blood Pressure; Bradycardia; Diltiazem; Dronedarone; Isoproterenol; Ivabradine; Myocardial Contraction; Swine

2013
Slow junctional rhythm, QTc prolongation and transient torsades de-pointes following combined use of Ivabradine, Diltiazem and Ranolazine.
    The Journal of the Association of Physicians of India, 2014, Volume: 62, Issue:5

    Topics: Acetanilides; Aged, 80 and over; Angina, Unstable; Benzazepines; Bradycardia; Diltiazem; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Electrocardiography; Female; Humans; Ivabradine; Long QT Syndrome; Piperazines; Ranolazine; Torsades de Pointes

2014