itraconazole and ravuconazole

itraconazole has been researched along with ravuconazole in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (11.36)	18.2507
2000's	24 (54.55)	29.6817
2010's	6 (13.64)	24.3611
2020's	9 (20.45)	2.80

Authors

Authors	Studies
Coleman, DC; Gee, S; Joly, S; Messer, SA; Pfaller, MA; Pujol, C; Soll, DR; Sullivan, DJ	1
Diekema, DJ; Doern, GV; Hollis, RJ; Houston, A; Jones, RN; Messer, SA; Pfaller, MA	1
Bonner, DP; Fung-Tomc, JC; Huczko, E; Minassian, B; White, TC	1
Denning, DW; Moore, CB; Walls, CM	1
Hollis, RJ; Houston, A; Jones, RN; Messer, SA; Pfaller, MA; Yamazumi, T	1
Calderon, L; Clemons, KV; Martinez, M; Stevens, DA	1
Ichihara, S; Murasaki, C; Ohwada, J; Shimma, N; Umeda, I; Yamazaki, T	1
Kamei, K	1
Diekema, DJ; Hollis, RJ; Jones, RN; Messer, SA; Pfaller, MA	1
Bonner, D; Fung-Tomc, J; Huczko, E; Minassian, B; Washo, T	1
Capilla, J; Guarro, J; Javier Pastor, F; Ortoneda, M; Pujol, I	1
Batra, R; Gupta, AK; Kohli, Y	1
Steinbach, WJ	1
Cano, J; Gené, J; Gilgado, F; Guarro, J; Serena, C	1
Denning, DW; Gardiner, RE; Howard, SJ; Moore, CB; Park, S; Perlin, DS; Webster, I	1
Alastruey-Izquierdo, A; Alcazar-Fuoli, L; Cuenca-Estrella, M; Mellado, E; Monzon, A; Rodriguez-Tudela, JL	1
Ayala, J; Elizondo, M; González, GM	1
Dannaoui, E; Lortholary, O; Schwarz, P	1
Vera-Cabrera, L; Welsh, E; Welsh, O	1
Guarro, J; Mayayo, E; Pastor, FJ; Pujol, I; Ruíz-Cendoya, M; Sutton, DA	1
Ahmed, SA; de Hoog, GS; Duncanson, F; Fahal, AH; Kloezen, W; van de Sande, WW; Zijlstra, EE	1
Ikeda, F; Iyoda, T; Mikawa, T; Suzuki, M; Yamaguchi, H	1
Aramaki, C; Kamata, H; Kano, R; Mori, Y; Murayama, N; Yamagishi, K; Yokoi, S	1
Ito, T; Kamata, H; Kano, R; Miura, A; Suzuki, K	1
Harada, K; Hase, M; Hiruma, J; Hiruma, M; Kamata, H; Kano, R; Noguchi, H; Yokota, M	1
Abastabar, M; Badali, H; Bonifaz, A; Fahal, A; Lim, W; Nyuykonge, B; van Amelsvoort, L; van de Sande, W; Verbon, A	1
Bakhiet, S; Fahal, AH; Mhmoud, NA; Nyaoke, BA; Nyuykonge, B; Siddig, EE; van de Sande, WWJ; Verbon, A; Zijlstra, EE	1
Hirasawa, Y; Hiruma, M; Ikeda, S; Kano, R; Komiyama, E; Ogawa, T; Ogawa, Y; Tsuchihashi, H; Watanabe, M	1
Harada, K; Hiruma, J; Hiruma, M; Kano, R; Noguchi, H; Shimizu, T	1
Harada, K; Hiruma, J; Hiruma, M; Kano, R; Makimura, K; Noguchi, H; Nojo, H	1
Algueró, M; Bartroli, J; Boncompte, E; Conte, L; Forn, J; García-Rafanell, J; Merlos, M; Ramis, J; Turmo, E; Vericat, ML	2
Alcázar-Fuoli, L; Cuenca-Estrella, M; Garcia-Effron, G; Melchers, WJ; Mellado, E; Rodríguez-Tudela, JL; Verweij, PE	1
Cano, J; Gené, J; Guarro, J; Marimon, R; Serena, C	1
Alastruey-Izquierdo, A; Alcazar-Fuoli, L; Cuenca-Estrella, M; Mellado, E; Rodriguez-Tudela, JL	2
Alastruey-Izquierdo, A; Almirante, B; Cuenca-Estrella, M; Gomez-Lopez, A; Pahissa, A; Rodriguez, D; Rodriguez-Tudela, JL	1
Azor, M; Cano, J; Fothergill, AW; Gené, J; Guarro, J; Rinaldi, MG; Sutton, DA	1
Alastruey-Izquierdo, A; Castelli, MV; Cuenca-Estrella, M; Cuesta, I; Mellado, E; Monzon, A; Rodriguez-Tudela, JL	1
Alastruey-Izquierdo, A; Cuenca-Estrella, M; Lass-Flörl, C; Perkhofer, S; Rodriguez-Tudela, JL	1
Alastruey-Izquierdo, A; Castelli, MV; Cuenca-Estrella, M; Cuesta, I; Monzon, A; Rodriguez-Tudela, JL	1
Alastruey-Izquierdo, A; Cuenca-Estrella, M; Cuesta, I; Rodriguez-Tudela, JL; Walther, G	1
Cai, T; Cao, X; Cao, Y; Chu, W; Hu, W; Sun, Z; Wang, R; Yang, Y	1
Emami, S; Ghobadi, E; Saednia, S	1

Reviews

4 review(s) available for itraconazole and ravuconazole

Article	Year
[Present status and future prospects of azole antifungal agents in Japan]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6 Topics: Antifungal Agents; Azoles; Cyclodextrins; Drug Design; Fluconazole; Forecasting; Itraconazole; Japan; Miconazole; Pyrimidines; Thiazoles; Triazoles; Voriconazole	2002
Antifungal agents in children. Pediatric clinics of North America, 2005, Volume: 52, Issue:3 Topics: Age Factors; Amphotericin B; Anidulafungin; Antifungal Agents; Caspofungin; Chemistry, Pharmaceutical; Child; Clinical Trials as Topic; Drug Approval; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Lipopeptides; Lipoproteins; Micafungin; Mycoses; Patient Selection; Pediatrics; Peptides, Cyclic; Pyrimidines; Safety; Thiazoles; Triazoles; United States; Voriconazole	2005
Onychomycosis. Clinics in dermatology, 2010, Mar-04, Volume: 28, Issue:2 Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Ciclopirox; Drug Administration Schedule; Drug Therapy, Combination; Fluconazole; Foot Dermatoses; Humans; Itraconazole; Mitosporic Fungi; Morpholines; Naphthalenes; Onychomycosis; Pyridones; Pyrimidines; Terbinafine; Thiazoles; Triazoles; Voriconazole	2010
Synthetic approaches and structural diversity of triazolylbutanols derived from voriconazole in the antifungal drug development. European journal of medicinal chemistry, 2022, Mar-05, Volume: 231 Topics: Antifungal Agents; Drug Development; Fungi; Voriconazole	2022

Other Studies

40 other study(ies) available for itraconazole and ravuconazole

Article	Year
In vitro susceptibilities of Candida dubliniensis isolates tested against the new triazole and echinocandin antifungal agents. Journal of clinical microbiology, 1999, Volume: 37, Issue:3 Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Candida; Candidiasis; Caspofungin; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Peptides; Peptides, Cyclic; Pyrimidines; Thiazoles; Triazoles; Voriconazole	1999
In vitro activities of BMS-207147 against over 600 contemporary clinical bloodstream isolates of Candida species from the SENTRY Antimicrobial Surveillance Program in North America and Latin America. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:9 Topics: Antifungal Agents; Candida; Dose-Response Relationship, Drug; Fluconazole; Humans; Itraconazole; Latin America; Microbial Sensitivity Tests; North America; Population Surveillance; Thiazoles; Triazoles	1999
In vitro antifungal activity of BMS-207147 and itraconazole against yeast strains that are non-susceptible to fluconazole. Diagnostic microbiology and infectious disease, 1999, Volume: 35, Issue:2 Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Thiazoles; Triazoles	1999
In vitro activity of the new triazole BMS-207147 against Aspergillus species in comparison with itraconazole and amphotericin B. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:2 Topics: Amphotericin B; Antifungal Agents; Aspergillus; Drug Resistance, Microbial; Humans; Itraconazole; Microbial Sensitivity Tests; Thiazoles; Triazoles	2000
In vitro activities of ravuconazole (BMS-207147) against 541 clinical isolates of Cryptococcus neoformans. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10 Topics: Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Humans; Itraconazole; Microbial Sensitivity Tests; Thiazoles; Triazoles	2000
Efficacy of ravuconazole in treatment of systemic murine histoplasmosis. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3 Topics: Animals; Antifungal Agents; Colony Count, Microbial; Female; Fluconazole; Histoplasmosis; Itraconazole; Liver; Mice; Spleen; Survival; Survival Analysis; Thiazoles; Triazoles	2002
Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals. Bioorganic & medicinal chemistry letters, 2002, Oct-07, Volume: 12, Issue:19 Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Azoles; Candida albicans; Candidiasis; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Prodrugs; Rats; Solubility; Thiazoles; Triazoles	2002
Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. Journal of clinical microbiology, 2003, Volume: 41, Issue:8 Topics: Amphotericin B; Anti-Bacterial Agents; Aspergillus; Caspofungin; Echinocandins; Fungi; Humans; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Mycoses; Penicillium; Peptides; Peptides, Cyclic; Pyrimidines; Thiazoles; Triazoles; Voriconazole	2003
In vitro activity of ravuconazole against Zygomycetes, Scedosporium and Fusarium isolates. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:12 Topics: Amphotericin B; Antifungal Agents; Fungi; Fusarium; Itraconazole; Microbial Sensitivity Tests; Pyrimidines; Scedosporium; Thiazoles; Triazoles; Voriconazole	2003
In vitro interactions of licensed and novel antifungal drugs against Fusarium spp. Diagnostic microbiology and infectious disease, 2004, Volume: 48, Issue:1 Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Drug Resistance, Fungal; Fusarium; Humans; Itraconazole; Microbial Sensitivity Tests; Naphthalenes; Pyrimidines; Quinazolines; Sensitivity and Specificity; Terbinafine; Thiazoles; Triazoles; Voriconazole	2004
In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species. Medical mycology, 2005, Volume: 43, Issue:2 Topics: Antifungal Agents; Arthrodermataceae; Fluconazole; Fungi; Humans; Itraconazole; Microbial Sensitivity Tests; Mycoses; Naphthalenes; Terbinafine; Thiazoles; Triazoles; Yeasts	2005
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:12 Topics: Amphotericin B; Antifungal Agents; Candida; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Naphthalenes; Peptides, Cyclic; Pseudallescheria; Pyrimidines; Quality Control; Quinazolines; Scedosporium; Terbinafine; Thiazoles; Triazoles; Voriconazole	2006
Multi-azole resistance in Aspergillus fumigatus. International journal of antimicrobial agents, 2006, Volume: 28, Issue:5 Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Caspofungin; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple, Fungal; Echinocandins; Fungal Proteins; Humans; Itraconazole; Lipopeptides; Lung Diseases, Fungal; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Peptides, Cyclic; Pyrimidines; Thiazoles; Triazoles; Voriconazole	2006
Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Amino Acid Substitution; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Azoles; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Genes, Fungal; Humans; Itraconazole; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Pyrimidines; Thiazoles; Triazoles; Voriconazole	2008
Trends in species distribution and susceptibility of bloodstream isolates of Candida collected in Monterrey, Mexico, to seven antifungal agents: results of a 3-year (2004 to 2007) surveillance study. Journal of clinical microbiology, 2008, Volume: 46, Issue:9 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Caspofungin; Child; Child, Preschool; Echinocandins; Female; Fluconazole; Humans; Infant; Infant, Newborn; Itraconazole; Lipopeptides; Male; Mexico; Microbial Sensitivity Tests; Middle Aged; Pyrimidines; Thiazoles; Triazoles; Voriconazole; Young Adult	2008
In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Amphotericin B; Antifungal Agents; Azoles; Cyclosporine; Drug Interactions; Immunosuppressive Agents; Itraconazole; Microbial Sensitivity Tests; Mucorales; Rhizopus; Sirolimus; Tacrolimus; Thiazoles; Triazoles	2009
In vitro and in vivo antifungal susceptibilities of the Mucoralean fungus Cunninghamella. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Amphotericin B; Animals; Antifungal Agents; Caspofungin; Cunninghamella; Diabetes Mellitus, Experimental; Echinocandins; Itraconazole; Lipopeptides; Male; Mice; Microbial Sensitivity Tests; Mucormycosis; Pyrimidines; Thiazoles; Triazoles; Voriconazole	2010
Madurella mycetomatis is highly susceptible to ravuconazole. PLoS neglected tropical diseases, 2014, Volume: 8, Issue:6 Topics: Antifungal Agents; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Thiazoles; Triazoles	2014
[In vitro antifungal activity of ravuconazole against isolates of dermatophytes and Candida species from patients with dermatomycoses]. Medical mycology journal, 2014, Volume: 55, Issue:4 Topics: Antifungal Agents; Arthrodermataceae; Candida; Dermatomycoses; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Humans; Itraconazole; Naphthalenes; Terbinafine; Thiazoles; Triazoles	2014
High multi-azole-resistant Malassezia pachydermatis clinical isolates from canine Malassezia dermatitis. Medical mycology, 2020, Feb-01, Volume: 58, Issue:2 Topics: Animals; Antifungal Agents; Azoles; Dermatomycoses; Dog Diseases; Dogs; Drug Resistance, Multiple, Fungal; Itraconazole; Japan; Malassezia; Microbial Sensitivity Tests; Thiazoles; Triazoles	2020
In vitro algaecid effect of itraconazole and ravuconazole on Prototheca species. Medical mycology, 2020, Aug-01, Volume: 58, Issue:6 Topics: Humans; Infections; Itraconazole; Microbial Sensitivity Tests; Prototheca; Thiazoles; Triazoles	2020
In Vitro Ravuconazole Susceptibility of Anthropophilic Dermatophyte Strains Isolated from Japanese Patients. Japanese journal of infectious diseases, 2020, May-22, Volume: 73, Issue:3 Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Drug Resistance, Fungal; Humans; Itraconazole; Microbial Sensitivity Tests; Terbinafine; Thiazoles; Triazoles	2020
Eumycetoma causative agents are inhibited in vitro by luliconazole, lanoconazole and ravuconazole. Mycoses, 2022, Volume: 65, Issue:6 Topics: Antifungal Agents; Humans; Imidazoles; Itraconazole; Madurella; Mycetoma; Thiazoles; Triazoles	2022
Epidemiological cut-off values for itraconazole and ravuconazole for Madurella mycetomatis, the most common causative agent of mycetoma. Mycoses, 2022, Volume: 65, Issue:12 Topics: Antifungal Agents; Humans; Itraconazole; Madurella; Mycetoma; Triazoles	2022
Antifungal Susceptibility Testing for Microsporum canis from Cats in Japan. Medical mycology journal, 2023, Volume: 64, Issue:1 Topics: Animals; Antifungal Agents; Canidae; Cats; Itraconazole; Japan; Terbinafine; Tinea	2023
Epidemiological study of antifungal-resistant dermatophytes isolated from Japanese patients. The Journal of dermatology, 2023, Volume: 50, Issue:8 Topics: Antifungal Agents; East Asian People; Humans; Itraconazole; Microbial Sensitivity Tests; Terbinafine; Trichophyton	2023
In vitro Azole Susceptibility Testing of Japanese Isolates of Itraconazole-Resistant Dermatophytes. Medical mycology journal, 2023, Volume: 64, Issue:4 Topics: Antifungal Agents; Arthrodermataceae; Azoles; Drug Resistance, Fungal; Itraconazole; Microbial Sensitivity Tests; Terbinafine; Trichophyton	2023
New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol. Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11 Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis; Colony Count, Microbial; Fungi; Male; Mice; Molecular Conformation; Pyrimidinones; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiophenes; Triazoles	1998
New azole antifungals. 3. Synthesis and antifungal activity of 3-substituted-4(3H)-quinazolinones. Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11 Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis; Colony Count, Microbial; Fungi; Male; Mice; Molecular Conformation; Quinazolines; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles	1998
A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Amino Acid Substitution; Antifungal Agents; Aspergillus fumigatus; Azoles; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Genotype; Humans; Microbial Sensitivity Tests; Tandem Repeat Sequences	2007
In vitro antifungal susceptibilities of five species of sporothrix. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Species Specificity; Sporothrix; Sporotrichosis	2008
Aspergillus section Fumigati: antifungal susceptibility patterns and sequence-based identification. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Antifungal Agents; Aspergillus fumigatus; Fungal Proteins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Nuclear Proteins; Phylogeny; Polymerase Chain Reaction; Sequence Analysis, DNA; Tubulin	2008
Prevalence and susceptibility profile of Candida metapsilosis and Candida orthopsilosis: results from population-based surveillance of candidemia in Spain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Antifungal Agents; Candida; Candidiasis; Fungemia; Humans; Microbial Sensitivity Tests; Population Surveillance; Prevalence; Spain; Species Specificity	2008
In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Fusarium; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mycoses; Naphthalenes; Sequence Analysis, DNA; Terbinafine; Triazoles; Tubulin	2008
Susceptibility testing and molecular classification of Paecilomyces spp. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Amphotericin B; Antifungal Agents; DNA, Fungal; DNA, Ribosomal; Echinocandins; Itraconazole; Microbial Sensitivity Tests; Paecilomyces; Phylogeny	2008
In vitro activities of various antifungal drugs against Aspergillus terreus: Global assessment using the methodology of the European committee on antimicrobial susceptibility testing. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Antifungal Agents; Aspergillosis; Aspergillus; DNA, Fungal; Humans; Microbial Sensitivity Tests; Soil Microbiology	2009
Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Amphotericin B; Antifungal Agents; DNA, Ribosomal Spacer; Microbial Sensitivity Tests; Mucorales; Triazoles	2009
Species identification and antifungal susceptibility patterns of species belonging to Aspergillus section Nigri. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Antifungal Agents; Aspergillus; Itraconazole; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny	2009
Antifungal susceptibility profile of human-pathogenic species of Lichtheimia. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Amphotericin B; Antifungal Agents; Humans; Microbial Sensitivity Tests; Mucorales; Pyrimidines; Triazoles; Voriconazole	2010
Design, synthesis, and structure-activity relationship studies of novel fused heterocycles-linked triazoles with good activity and water solubility. Journal of medicinal chemistry, 2014, May-08, Volume: 57, Issue:9 Topics: Animals; Antifungal Agents; Area Under Curve; Candida; Drug Design; Drug Evaluation, Preclinical; Half-Life; Heterocyclic Compounds; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Molecular Docking Simulation; Rats; Solubility; Structure-Activity Relationship; Triazoles; Water	2014