Compounds > itraconazole

itraconazole and heme

itraconazole has been researched along with heme in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Barbuch, R; Bard, M; Gachotte, D; Koegel, C; Lees, ND; Pierson, CA1
Hutzler, JM; Locuson, CW; Tracy, TS1
Akiyoshi, T; Guengerich, FP; Miyazaki, M; Murase, S; Murayama, N; Nakamura, K; Ohtani, H; Saito, T; Yamamoto, K; Yamazaki, H1
Isoherranen, N; Kunze, KL; Liu, JO; Lutz, JD; Nelson, WL; Peng, CC; Shi, W1
Chen, M; Chen, P; Li, L; Wang, S; Zhong, G1

Other Studies

5 other study(ies) available for itraconazole and heme

ArticleYear
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Antifungal Agents; Azoles; Clotrimazole; Genes, Fungal; Genotype; Heme; Itraconazole; Ketoconazole; Lanosterol; Mixed Function Oxygenases; Mutation; Saccharomyces cerevisiae; Sterols; Suppression, Genetic

1997
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles

2007
Comparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variants.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:4

    Topics: 14-alpha Demethylase Inhibitors; Androgens; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Genetic Variation; Heme; Humans; Hydroxytestosterones; Itraconazole; Recombinant Proteins; Testosterone

2011
Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:3

    Topics: Antifungal Agents; Azoles; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxolanes; Female; Heme; Humans; Hydroxylation; Iron; Itraconazole; Male; Metabolic Networks and Pathways; Midazolam; Stereoisomerism; Triazoles

2012
Deletion of
    Antimicrobial agents and chemotherapy, 2022, 06-21, Volume: 66, Issue:6

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Electron Transport Complex IV; Ergosterol; Fungal Proteins; Heme; Humans; Itraconazole; Microbial Sensitivity Tests; Nuclear Proteins

2022