itraconazole and ergosterol

itraconazole has been researched along with ergosterol in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.50)18.7374
1990's9 (22.50)18.2507
2000's8 (20.00)29.6817
2010's17 (42.50)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Ballard, SA; Ellis, SW; Kelly, SL; Troke, PF1
Hart, DT; Lauwers, WJ; Opperdoes, FR; Vanden Bossche, H; Willemsens, G1
Geerts, H; Gorrens, J; Janssen, PA; Marichal, P; Vanden Bossche, H1
Rippon, JW1
Brasini, S; De Luca, C; Fabbri, AA; Fanelli, C; Passi, S1
Baldwin, BC; Corran, A; Kelly, SL; Kwon-Chung, J; Lamb, DC1
Bartlett, MS; Queener, SF; Richardson, JD; Shaw, MM; Smith, JW1
Coene, MC; Cools, W; Gorrens, J; Le Jeune, L; Marichal, P; Vanden Bossche, H1
Connolly, P; Le Monte, A; Marichal, P; Vanden Bossche, H; Wheat, J1
Denning, DW; Kelly, SL; Venkateswarlu, K1
Leyden, J1
Borgers, M; Gorrens, J; Laurijssens, L; Le Jeune, L; Marichal, P; Odds, F; Ramaekers, FC; Sanglard, D; Van Hove, C; Vanden Bossche, H; Verhasselt, P; Vermuyten, K1
Borel, E; Dannaoui, E; Persat, F; Picot, S; Piens, MA1
Evans, EG1
Arthington-Skaggs, BA; Brandt, ME; Ciblak, MA; Frade, JP; Hajjeh, RA; Harrison, LH; Lee-Yang, W; Sofair, AN; Warnock, DW1
Le Baut, G; Le Borgne, M; Le Pape, P; Marchand, P; Na, YM; Pagniez, F; Robert-Piessard, S1
Ausma, J; Bohets, H; Borgers, M; Marichal, P; Meerpoel, L; Odds, F; Vanden Bossche, H; Vermuyten, K; Willemsens, G1
Han, XY; Hassan, SA; Matsuda, SP; May, GS; Tarrand, JJ; Wilson, WK; Xiong, Q1
Bien, CM; Chang, YC; Espenshade, PJ; Kwon-Chung, KJ; Lee, H1
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M1
Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, NJ; Warrilow, AG1
Dan, H; Jinhua, L; Lei, G; Li, W; Song, G; Wei, Y1
Kontoyiannis, DP; Lewis, RE; Lortholary, O; Roilides, E; Spellberg, B; Walsh, TJ1
Bulgheroni, A; Celandroni, F; Ghelardi, E; Gueye, SA; Mailland, F; Salvetti, S; Senesi, S1
Bailão, AM; Carvalho, PF; da Silva Neto, BR; Martins, WS; Pereira, M; Soares, CM1
Anyatonwu, H; Chaudhuri, M; Haubrich, BA; Leaver, DJ; Lecordier, L; Miller, MB; Nes, CR; Nes, WD; Patkar, P; Singha, UK; Vanhollebeke, B; Villalta, F1
de Macedo-Silva, ST; de Souza, W; Rodrigues, JC; Urbina, JA; Visbal, G1
Alencar, LP; Bandeira, TJPG; Brilhante, RSN; Cordeiro, RA; Evangelista, AJJ; Franco, JDS; Marques, FJF; Melo, CVS; Oliveira, JS; Rocha, MFG; Serpa, R; Sidrim, JJC1
Alencar, LP; Bandeira, SP; Bandeira, TJ; Brandine, GS; Brilhante, RS; Castelo-Branco, DS; Cordeiro, RA; Guedes, GM; Melo, LM; Moreira, JL; Paiva, MA; Pereira-Neto, WA; Ponte, YB; Rocha, MF; Sales, JA; Sidrim, JJ1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG1
Bandeira, Tde J; Brilhante, RS; Caetano, EP; Cordeiro, Rde A; da Silva, MR; de Melo, CV; de Oliveira, Mda C; Evangelista, AJ; Mafezoli, J; Marques, FJ; Moreira, JL; Rocha, MF; Serpa, R; Sidrim, JJ1
DuBois, JC; Smulian, AG1
Long, N; Lu, L; Sang, H; Xu, X; Zeng, Q1
Alterovitz, G; Cheng, L; Luo, H; Ren, B; Tang, F; Yang, H; Yang, J; Zhou, X; Zhou, Y1
Keniya, MV; Monk, BC; Ruma, YN; Tyndall, JDA1
Ballard, E; Brakhage, AA; Brown, AJP; Melchers, WJG; Tammireddy, S; Verweij, PE; Warris, A; Weber, J; Whitfield, PD1
Araújo, NMS; da Costa, HPS; da Silva Neto, JX; de Oliveira Bezerra de Sousa, D; Dias, LP; Guedes, MIF; Lopes, LA; Lopes, TDP; Morais, EG; Moura, LFWG; Oliveira, JTA; Pereira, ML; Van Tilburg, MF; Vasconcelos, IM1
Castanheira, M; Collingsworth, TD; Davis, AP; Deshpande, LM; Pfaller, MA1
Chen, M; Chen, P; Li, L; Wang, S; Zhong, G1
Cannon, RD; Holmes, AR; Lamping, E; Nakamura, K; Niimi, K; Niimi, M; Ranchod, A; Tyndall, JD1

Reviews

2 review(s) available for itraconazole and ergosterol

ArticleYear
Pharmacokinetics and pharmacology of terbinafine and itraconazole.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 3

    Topics: Antifungal Agents; Arthrodermataceae; Candida; Dermatomycoses; Dose-Response Relationship, Drug; Ergosterol; Humans; Itraconazole; Metabolic Clearance Rate; Nails; Naphthalenes; Terbinafine

1998
The rationale for combination therapy.
    The British journal of dermatology, 2001, Volume: 145 Suppl 60

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Arthrodermataceae; Cell Wall; Drug Therapy, Combination; Ergosterol; Humans; Itraconazole; Morpholines; Naphthalenes; Onychomycosis; Recurrence; Terbinafine

2001

Other Studies

38 other study(ies) available for itraconazole and ergosterol

ArticleYear
A novel method for studying ergosterol biosynthesis by a cell-free preparation of Aspergillus fumigatus and its inhibition by azole antifungal agents.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1990, Volume: 28, Issue:4

    Topics: Antifungal Agents; Aspergillus fumigatus; Autoradiography; Azoles; Chromatography, Thin Layer; Ergosterol; Fluconazole; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Molecular Structure

1990
Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages.
    Molecular and biochemical parasitology, 1989, Mar-01, Volume: 33, Issue:2

    Topics: Acetates; Animals; Antiprotozoal Agents; Cell Division; Cell Line; Cholesterol; Ergosterol; Itraconazole; Ketoconazole; Leishmania mexicana; Macrophages; Sterols

1989
Mode of action studies. Basis for the search of new antifungal drugs.
    Annals of the New York Academy of Sciences, 1988, Volume: 544

    Topics: Acetates; Antifungal Agents; Candida; Candida albicans; Cytochrome P-450 Enzyme System; Drug Design; Ergosterol; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Microsomes

1988
A new era in antimycotic agents.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Animals; Antifungal Agents; Azoles; Candida albicans; Chitin; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Dogs; Ergosterol; Fungi; Humans; Itraconazole; Ketoconazole; Lanosterol; Liver; Rats; Sterols

1986
Effect of different inhibitors of sterol biosynthesis on both fungal growth and aflatoxin production.
    Natural toxins, 1995, Volume: 3, Issue:2

    Topics: Aflatoxins; Antifungal Agents; Aspergillus; Culture Media; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Econazole; Ergosterol; Fatty Acids; Itraconazole; Ketoconazole; Miconazole

1995
Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cryptococcosis; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Drug Tolerance; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Microsomes; Oxidoreductases; Sterol 14-Demethylase; Sterols; Treatment Failure

1995
Pneumocystis carinii is resistant to imidazole antifungal agents.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Animals; Antifungal Agents; Ergosterol; Female; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Miconazole; Pneumocystis; Rats; Rats, Sprague-Dawley; Triazoles

1994
Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:10

    Topics: Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ergosterol; Itraconazole; Ketosteroids; Lanosterol; Methylation; Oxidation-Reduction; Sterols

1993
Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Drug Resistance, Microbial; Ergosterol; Fluconazole; Histoplasma; Histoplasmosis; Humans; Itraconazole; Male; Microbial Sensitivity Tests; Polymerase Chain Reaction

1997
In-vitro activity of D0870, a new triazole antifungal drug, in comparison with fluconazole and itraconazole against Aspergillus fumigatus and Candida krusei.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:6

    Topics: Antifungal Agents; Aspergillus fumigatus; Candida; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ergosterol; Fluconazole; Itraconazole; Time Factors; Triazoles

1997
Accumulation of 3-ketosteroids induced by itraconazole in azole-resistant clinical Candida albicans isolates.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:11

    Topics: Antifungal Agents; Azoles; Candida albicans; DNA-Binding Proteins; Drug Resistance, Microbial; Ergosterol; Itraconazole; Ketosteroids; Microbial Sensitivity Tests; Mixed Function Oxygenases; Polymerase Chain Reaction; Trans-Activators; Transcription Factors; Transcriptional Regulator ERG

1999
Sterol composition of itraconazole-resistant and itraconazole-susceptible isolates of Aspergillus fumigatus.
    Canadian journal of microbiology, 2001, Volume: 47, Issue:8

    Topics: Antifungal Agents; Aspergillus fumigatus; Drug Resistance, Fungal; Ergosterol; Humans; Itraconazole; Microbial Sensitivity Tests; Sterols

2001
Comparison of visual and spectrophotometric methods of broth microdilution MIC end point determination and evaluation of a sterol quantitation method for in vitro susceptibility testing of fluconazole and itraconazole against trailing and nontrailing Cand
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8

    Topics: Antifungal Agents; Candida; Candidiasis; Endpoint Determination; Ergosterol; Fluconazole; Indicator Dilution Techniques; Itraconazole; Microbial Sensitivity Tests; Spectrophotometry; Sterols

2002
In vitro activity of a new antifungal azolyl-substituted indole against Aspergillus fumigatus.
    Journal of enzyme inhibition and medicinal chemistry, 2002, Volume: 17, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Aspergillus fumigatus; Ergosterol; Hyphae; Indoles; Itraconazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Phospholipases A; Phospholipases A2

2002
The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Adrenal Cortex; Androgens; Animals; Antifungal Agents; Candida albicans; Cattle; Cells, Cultured; Cholesterol; Cytochrome P-450 Enzyme System; Epidermis; Ergosterol; Estrogens; Humans; Imidazoles; In Vitro Techniques; Itraconazole; Kidney; Male; Microsomes; Microsomes, Liver; Microsporum; Mitochondria; Pharmaceutical Preparations; Placenta; Rats; Rats, Wistar; Steroid 11-beta-Hydroxylase; Testis; Tretinoin; Triazoles; Trichophyton

2004
Cholesterol import by Aspergillus fumigatus and its influence on antifungal potency of sterol biosynthesis inhibitors.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Cell Membrane; Cholesterol; Culture Media, Conditioned; Ergosterol; Humans; Itraconazole; Magnetic Resonance Spectroscopy; Oxygen Consumption; Pyrimidines; Spores, Fungal; Sterols; Triazoles; Voriconazole

2005
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans.
    Molecular microbiology, 2007, Volume: 64, Issue:3

    Topics: Animals; Antifungal Agents; Azoles; Blotting, Northern; Brain; Cryptococcus neoformans; Electrophoresis, Polyacrylamide Gel; Ergosterol; Female; Fungal Proteins; Gene Expression Regulation, Fungal; Genome, Fungal; Homeostasis; Iron; Itraconazole; Mice; Mice, Inbred BALB C; Models, Biological; Oligonucleotide Array Sequence Analysis; Oxygen; Sterol Regulatory Element Binding Proteins; Sterols; Virulence

2007
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole

2010
Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Aspergillus fumigatus; Azoles; Clotrimazole; Cytochrome P-450 Enzyme System; Doxycycline; Ergosterol; Fluconazole; Fungal Proteins; Genetic Complementation Test; Itraconazole; Pyrimidines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triazoles; Voriconazole

2010
Berberine and itraconazole are not synergistic in vitro against Aspergillus fumigatus isolated from clinical patients.
    Molecules (Basel, Switzerland), 2011, Nov-03, Volume: 16, Issue:11

    Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Berberine; Ergosterol; Gene Expression Profiling; Gene Expression Regulation, Fungal; Humans; Itraconazole; Microbial Sensitivity Tests; Molecular Structure

2011
How does antifungal pharmacology differ for mucormycosis versus aspergillosis?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 54 Suppl 1

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Cell Membrane; Cell Wall; Drug Resistance, Multiple, Fungal; Ergosterol; Gene Duplication; Genome, Fungal; Genomic Instability; Humans; Itraconazole; Microbial Sensitivity Tests; Mucormycosis; Pyrimidines; Rhizopus; Species Specificity; Triazoles; Virulence Factors; Voriconazole

2012
Potential of Ergosterol synthesis inhibitors to cause resistance or cross-resistance in Trichophyton rubrum.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:5

    Topics: Antifungal Agents; Ciclopirox; Drug Resistance, Fungal; Ergosterol; Itraconazole; Microbial Sensitivity Tests; Morpholines; Naphthalenes; Pyridones; Terbinafine; Trichophyton

2014
Transcriptional profile of Paracoccidioides spp. in response to itraconazole.
    BMC genomics, 2014, Apr-01, Volume: 15

    Topics: Adaptation, Biological; Antifungal Agents; Biological Transport; Computational Biology; Ergosterol; Gene Expression Profiling; Gene Expression Regulation, Fungal; Genes, Fungal; Itraconazole; Models, Biological; Paracoccidioides; Transcription, Genetic; Transcriptome

2014
Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth.
    Journal of lipid research, 2015, Volume: 56, Issue:2

    Topics: Animals; Cholesterol; Ergosterol; Itraconazole; Male; Methyltransferases; Mice; Mice, Inbred BALB C; Protozoan Proteins; RNA; Trypanosoma brucei brucei

2015
Potent In Vitro Antiproliferative Synergism of Combinations of Ergosterol Biosynthesis Inhibitors against Leishmania amazonensis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: 14-alpha Demethylase Inhibitors; Animals; Culture Media; Drug Synergism; Drug Therapy, Combination; Ergosterol; Farnesyl-Diphosphate Farnesyltransferase; Humans; Itraconazole; Leishmania mexicana; Leishmaniasis, Diffuse Cutaneous; Lipid Droplets; Membrane Potential, Mitochondrial; Mice; Mitochondria; Parasitic Sensitivity Tests; Pyridines; Quinuclidines; Reactive Oxygen Species; Sterol 14-Demethylase; Triazoles; Trypanocidal Agents

2015
Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species complex.
    Microbiology (Reading, England), 2016, Volume: 162, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Biofilms; Caenorhabditis elegans; Cell Membrane; Cryptococcosis; Cryptococcus gattii; Cryptococcus neoformans; Ergosterol; Fluconazole; HSP90 Heat-Shock Proteins; Humans; Itraconazole; Melanins; Microbial Sensitivity Tests; Plankton; Voriconazole

2016
Cross-resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
    Mycoses, 2016, Volume: 59, Issue:5

    Topics: Animals; Anti-Allergic Agents; Antifungal Agents; ATP-Binding Cassette Transporters; Candida; Chlorobenzenes; Drug Resistance, Microbial; Ergosterol; Fluconazole; Fungicides, Industrial; Gene Expression Regulation, Fungal; Humans; Itraconazole; Malathion; Microbial Sensitivity Tests; Promethazine; Rhodamines; Sterol 14-Demethylase; Triazoles; Voriconazole

2016
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole

2016
Synthesis and in vitro antifungal activity of isoniazid-derived hydrazones against Coccidioides posadasii.
    Microbial pathogenesis, 2016, Volume: 98

    Topics: Amphotericin B; Antifungal Agents; Biosynthetic Pathways; Cell Membrane; Coccidioides; Drug Synergism; Ergosterol; Hydrazones; Itraconazole; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Permeability

2016
Sterol Regulatory Element Binding Protein (Srb1) Is Required for Hypoxic Adaptation and Virulence in the Dimorphic Fungus Histoplasma capsulatum.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Adaptation, Physiological; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Ergosterol; Fungal Proteins; Gene Expression Regulation, Fungal; Gene Silencing; Histoplasma; Itraconazole; Macrophages; Mice; Oxygen; Virulence

2016
Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus.
    Applied and environmental microbiology, 2017, 02-15, Volume: 83, Issue:4

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Drug Resistance, Fungal; Ergosterol; Gene Deletion; Gene Expression Regulation, Fungal; Humans; Itraconazole; Mice; Microbial Sensitivity Tests; Oxidoreductases; Saccharomyces cerevisiae Proteins; Spores, Fungal; Voriconazole

2017
Lovastatin synergizes with itraconazole against planktonic cells and biofilms of Candida albicans through the regulation on ergosterol biosynthesis pathway.
    Applied microbiology and biotechnology, 2018, Volume: 102, Issue:12

    Topics: Antifungal Agents; Biofilms; Candida albicans; Ergosterol; Fungal Proteins; Gene Expression Regulation, Fungal; Itraconazole; Lovastatin; Microbial Sensitivity Tests; Mutation

2018
Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Candida glabrata; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Humans; Itraconazole; Lanosterol; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Sterol 14-Demethylase; Triazoles; Voriconazole

2018
Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism.
    Fungal genetics and biology : FG & B, 2019, Volume: 130

    Topics: Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Azoles; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Cas Systems; Drug Resistance, Multiple, Fungal; Ergosterol; Fungal Proteins; Genotype; Host-Pathogen Interactions; Humans; Itraconazole; Microbial Sensitivity Tests; Mycelium; Phenotype; Polymorphism, Single Nucleotide

2019
Role of membrane sterol and redox system in the anti-candida activity reported for Mo-CBP
    International journal of biological macromolecules, 2020, Jan-15, Volume: 143

    Topics: Animals; Antifungal Agents; Antioxidants; Candida; Cell Membrane; Cell Survival; Chlorocebus aethiops; Cytochromes c; DNA Fragmentation; Ergosterol; Glucose; Itraconazole; Lipid Peroxidation; Moringa oleifera; Nystatin; Oxidation-Reduction; Plant Proteins; Reactive Oxygen Species; Seeds; Sterols; Vero Cells

2020
Isavuconazole nonwildtype Aspergillus fumigatus isolates from a global surveillance study display alterations in multiple genes involved in the ergosterol biosynthesis pathway not previously associated with resistance to other azoles.
    Mycoses, 2021, Volume: 64, Issue:10

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Drug Resistance, Fungal; Ergosterol; Fungal Proteins; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole; Whole Genome Sequencing

2021
Deletion of
    Antimicrobial agents and chemotherapy, 2022, 06-21, Volume: 66, Issue:6

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Electron Transport Complex IV; Ergosterol; Fungal Proteins; Heme; Humans; Itraconazole; Microbial Sensitivity Tests; Nuclear Proteins

2022
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Blotting, Northern; Blotting, Southern; Candida; Candidiasis; Cell Membrane; Chromosomes, Fungal; Drug Resistance, Fungal; Endoplasmic Reticulum; Humans; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae

2009