itaconic acid and succinic acid

itaconic acid has been researched along with succinic acid in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's1 (5.00)18.2507
2000's1 (5.00)29.6817
2010's8 (40.00)24.3611
2020's8 (40.00)2.80

Authors

AuthorsStudies
Hosono, H; Ohta, T; Tsukamoto, S; Yokosawa, H; Yoshida, T1
Ko, YH; McFadden, BA; Munske, GR; Vanni, P1
Cleland, WW; Schloss, JV1
COOPER, RA; ITIABA, K; KORNBERG, HL1
Cabrales, P; Cordes, T; Divakaruni, AS; Hiller, K; Koseki, H; Metallo, CM; Michelucci, A; Murphy, AN; Sapcariu, SC; Sousa, C; Wallace, M1
Artyomov, MN; Bambouskova, M; Cervantes-Barragan, L; Diamond, MS; Diwan, A; Griss, T; Huang, SC; Jones, RG; Khader, S; Lampropoulou, V; Loginicheva, E; Ma, X; Nair, S; Pearce, EJ; Randolph, GJ; Sergushichev, A; Vincent, EE; Weinheimer, CJ1
Burant, CF; ElAzzouny, M; Evans, CR; Gallagher, KA; Martin, BR; Olson, LL; Tanga, MJ; Tom, CT1
Hiller, K; Nonnenmacher, Y1
Murphy, MP; O'Neill, LAJ1
Bohannon, JK; Hernandez, A; Patil, NK; Patil, TK; Sherwood, ER1
Chouchani, ET; Frezza, C; Mills, EL; Murphy, MP; O'Neill, LA; Prag, HA; Ryan, DG1
Bailey, JD; Channon, KM; Chuaiphichai, S; Crabtree, MJ; Davis, S; Diotallevi, M; Fischer, R; Hale, A; Kessler, BM; McCullagh, J; McNeill, E; McShane, H; Nandi, M; Nicol, T; Shaw, A; Starr, A; Stylianou, E1
O'Neill, LAJ; Zasłona, Z1
Annavajhala, MK; Britto, CJ; Dach, F; Drikic, M; Francoeur, NJ; Gabryszewski, SJ; Groves, RA; Kahl, BC; Khanal, S; Lewis, I; Lung, TWF; Prince, AS; Riquelme, SA; Sebra, R; Smith, ML; Sridhar, SH; Tomlinson, KL; Uhlemann, AC1
Chun, HL; Ha, HJ; Kwon, S; Lee, SY; Park, HH1
Chen, YH; Gao, W; Li, P; Li, Y; Li, YC; Liu, B; Liu, XT; Yang, H; Zhang, L; Zhao, Q1
Goslen, KH; Hutchins, DC; Mainali, R; Oh, TS; Quinn, MA1
Beloborodova, N; Fedotcheva, N1
Aso, Y; Kataoka, C; Long, BHD; Miyazaki, C; Tanaka, K; Tanaka, T1
Chen, F; Cordes, T; Dowerg, B1

Reviews

6 review(s) available for itaconic acid and succinic acid

ArticleYear
Biochemistry of proinflammatory macrophage activation.
    Cellular and molecular life sciences : CMLS, 2018, Volume: 75, Issue:12

    Topics: Animals; Communicable Diseases; Energy Metabolism; Glycolysis; Humans; Inflammation; Macrophage Activation; Macrophages; Metabolic Networks and Pathways; Reactive Oxygen Species; Succinates; Succinic Acid

2018
Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.
    Cell, 2018, 08-09, Volume: 174, Issue:4

    Topics: Animals; Citric Acid Cycle; Humans; Signal Transduction; Succinates; Succinic Acid

2018
Regulation of leukocyte function by citric acid cycle intermediates.
    Journal of leukocyte biology, 2019, Volume: 106, Issue:1

    Topics: Animals; Citric Acid; Citric Acid Cycle; Fumarates; Humans; Leukocytes; Reactive Oxygen Species; Succinates; Succinic Acid

2019
Coupling Krebs cycle metabolites to signalling in immunity and cancer.
    Nature metabolism, 2019, Volume: 1

    Topics: Citric Acid Cycle; Humans; Immunity, Innate; Macrophages; Neoplasms; Signal Transduction; Succinate Dehydrogenase; Succinates; Succinic Acid

2019
Cytokine-like Roles for Metabolites in Immunity.
    Molecular cell, 2020, 06-04, Volume: 78, Issue:5

    Topics: Animals; Carboxylic Acids; Citric Acid Cycle; Cytokines; Energy Metabolism; Humans; Immunity; Inflammation; Ketoglutaric Acids; Lactic Acid; Signal Transduction; Succinates; Succinic Acid

2020
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment.
    Current opinion in biotechnology, 2023, Volume: 84

    Topics: Humans; Neoplasms; Succinates; Succinic Acid; Tumor Microenvironment

2023

Other Studies

14 other study(ies) available for itaconic acid and succinic acid

ArticleYear
Hexylitaconic acid: a new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp.
    Bioorganic & medicinal chemistry letters, 2006, Jan-01, Volume: 16, Issue:1

    Topics: Ascomycota; Chemistry, Pharmaceutical; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fungal Proteins; Humans; Inhibitory Concentration 50; Models, Chemical; Protein Binding; Proto-Oncogene Proteins c-mdm2; Succinates; Tumor Suppressor Protein p53

2006
Substrate-decreased modification by diethyl pyrocarbonate of two histidines in isocitrate lyase from Escherichia coli.
    Biochemistry, 1991, Jul-30, Volume: 30, Issue:30

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Diethylamines; Escherichia coli; Glyoxylates; Histidine; Hydrogen-Ion Concentration; Isocitrate Lyase; Isocitrates; Kinetics; Macromolecular Substances; Molecular Sequence Data; Spectrophotometry, Ultraviolet; Succinates; Succinic Acid

1991
Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue.
    Biochemistry, 1982, Aug-31, Volume: 21, Issue:18

    Topics: Chromatography, Gel; Glutarates; Glyoxylates; Isocitrate Lyase; Kinetics; Maleates; Nitro Compounds; Oxo-Acid-Lyases; Propionates; Pseudomonas; Succinates; Succinic Acid

1982
THE UTILIZATION OF ACONATE AND ITACONATE BY MICROCOCCUS SP.
    The Biochemical journal, 1965, Volume: 94

    Topics: Acetyl Coenzyme A; Aldehydes; Carbon Dioxide; Citric Acid Cycle; Coenzyme A; L-Lactate Dehydrogenase; Metabolism; Micrococcus; NAD; NADP; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Spectrophotometry; Succinates; Succinic Acid

1965
Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
    The Journal of biological chemistry, 2016, Jul-01, Volume: 291, Issue:27

    Topics: Animals; Cell Line; Hydro-Lyases; Lipopolysaccharides; Macrophages; Mice; Succinate Dehydrogenase; Succinates; Succinic Acid

2016
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
    Cell metabolism, 2016, 07-12, Volume: 24, Issue:1

    Topics: Animals; Cell Respiration; Female; Inflammation; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice, Inbred C57BL; Mitochondria; Reactive Oxygen Species; Reperfusion Injury; Succinate Dehydrogenase; Succinates; Succinic Acid

2016
Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.
    The Journal of biological chemistry, 2017, 03-24, Volume: 292, Issue:12

    Topics: Animals; Cells, Cultured; Inflammation; Lipopolysaccharides; Macrophages; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Succinates; Succinic Acid

2017
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
    Cell reports, 2019, 07-02, Volume: 28, Issue:1

    Topics: Animals; Biopterins; Citric Acid Cycle; Electron Transport; Endotoxemia; Glycolysis; GTP Cyclohydrolase; Inflammation; Interferon-gamma; Interleukin-1beta; Isocitrate Dehydrogenase; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Knockout; Mitochondria; Mycobacterium Infections; Nitric Oxide; Nitric Oxide Synthase Type II; Peptide Fragments; Proteome; Succinates; Succinic Acid; Tandem Mass Spectrometry

2019
Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation.
    Nature communications, 2021, 03-03, Volume: 12, Issue:1

    Topics: Adult; Animals; Biofilms; Bronchoalveolar Lavage Fluid; Carbohydrate Metabolism; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Glycolysis; Host-Pathogen Interactions; Humans; Hydro-Lyases; Mice, Inbred C57BL; Pseudomonas Infections; Reactive Oxygen Species; Sputum; Staphylococcal Infections; Staphylococcus aureus; Stress, Physiological; Succinates; Succinic Acid; Young Adult

2021
Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Catalysis; Catalytic Domain; Glyoxylates; Isocitrate Lyase; Isocitrates; Mycobacterium tuberculosis; Protein Conformation; Succinates; Succinic Acid

2021
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation.
    Cell reports, 2022, 02-15, Volume: 38, Issue:7

    Topics: Acetylation; Animals; Biological Transport; Carrier Proteins; Citric Acid; Citric Acid Cycle; Histones; Hydro-Lyases; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophage Activation; Macrophages; Mice, Inbred C57BL; Mitochondria; NAD; Organelle Biogenesis; Oxidation-Reduction; Succinates; Succinic Acid; Thrombosis; Transcription, Genetic; Zebrafish

2022
Itaconate and Its Derivatives Repress Early Myogenesis
    Frontiers in immunology, 2022, Volume: 13

    Topics: Muscle Development; Signal Transduction; Succinates; Succinic Acid

2022
Influence of Microbial Metabolites and Itaconic Acid Involved in Bacterial Inflammation on the Activity of Mitochondrial Enzymes and the Protective Role of Alkalization.
    International journal of molecular sciences, 2022, Aug-14, Volume: 23, Issue:16

    Topics: Glutamate Dehydrogenase; Glutamic Acid; Humans; Inflammation; Mitochondria; Oxidation-Reduction; Pyridines; Succinate Dehydrogenase; Succinates; Succinic Acid

2022
Photoclick reaction for rapid and simple fluorescence detection of itaconic acid and its derivatives in fungal cultures.
    Analytical and bioanalytical chemistry, 2023, Volume: 415, Issue:19

    Topics: Glucose; Reducing Agents; Succinates; Succinic Acid

2023