isradipine and verapamil

isradipine has been researched along with verapamil in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (24.21)	18.7374
1990's	50 (52.63)	18.2507
2000's	14 (14.74)	29.6817
2010's	8 (8.42)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dietel, M; Höllt, V; Kouba, M; Vogt, G	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Araie, E; Miwa, K; Miyagi, Y; Sasayama, S	1
Colombo, G; Fadda, F; Garau, B; Gessa, GL	1
Mason, RP; Moisey, DM; Shajenko, L	1
Glossmann, H; Knaus, HG; Staudinger, R	1
Keith, RA; Moore, WC; Patel, J; Salama, AI	1
Böhm, M; Erdmann, E; Schwinger, RH	3
Naitoh, T; Sugimoto, T; Toyo-Oka, T	1
Rampe, D; Triggle, DJ; Zheng, W	1
Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A	1
Murphy, BJ; Tuana, BS	1
Pinchuk, GV; Pinchuk, LN; Rudenko, AE; Tkachenko, YV	1
Asahina, T; Ikebuchi, M; Kashiwagi, A; Kodama, M; Nishio, Y; Ogawa, T; Shigeta, Y	1
Beaufort, P; Chatelain, P; Clinet, M; Laruel, R; Meysmans, L; Nokin, P	1
Dacquet, C; Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I	1
Harada, Y; Kimura, R; Nakayama, K; Yamada, S	1
Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG	1
Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I	1
Hosey, MM; McMahon, KK; Ptasienski, J	1
Benavides, J; Bertrand, P; Burgevin, MC; Doble, A; Ferris, O; Gueremy, C; Le Fur, G; Menager, J; Uzan, A; Vaucher, N	1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J	1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A	1
Hofmann, F; Nastainczyk, W; Sieber, M; Wernet, W; Zubor, V	1
Highsmith, RF; Schwartz, A; Whitmer, KR; Williams-Lawson, JS	1
Becker, C; Porzig, H	1
Dunn, SM	2
Dillon, JS; Gu, XH; Nayler, WG	1
Fitscha, P; Gazsó, A; Gludovacz, D; Sinzinger, H; Weiss, K	1
Dillon, JS; Gu, XH; Liu, JJ; Nayler, WG	1
Hudecová, S; Krizanová, O; Orlický, J; Zachar, J	1
Ferry, DR; Glossmann, H; Goll, A; Linn, T	1
Garcia, L; Lazdunski, M; Rieger, F; Romey, G	1
Hof, RP	1
Cook, NS; Hof, RP	1
Bevan, JA; Hwa, JJ	1
Hoch, K; Johnson, BF; Johnson, J; Marwaha, R; Wilson, J	1
Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H	1
Johnson, BF; Johnson, J; Ritchie, P; Rodin, SM; Wilson, J	1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M	1
Reynolds, IJ; Snowman, AM; Snyder, SH	1
Arneric, SP; Donnelly-Roberts, DL; Sullivan, JP	1
Bosse, E; Flockerzi, V; Hofmann, F; Lacinová, L; Ludwig, A	1
Akimoto, T; Ichida, S; Kishino, H; Matsuda, N; Nakazaki, S; Wada, T	1
Bosse, E; Donatin, K; Flockerzi, V; Hofmann, F; Lacinova, L; Ludwig, A; Welling, A	1
Anderson, K; Meissner, G	1
Carozzi, S; Fontana, I; Nasini, MG; Nocera, A; Pietrucci, A; Valente, U	1
Locher, R; Lupo, E; Vetter, W; Weisser, B	1
Docherty, JC; Dubo, DF; Lonsberry, BB; Maddaford, TG; Pierce, GN; Thomas, SM	1
Lombet, A; Spedding, M	1
Boksa, P; Quirion, R; Sen, AP	1
Coutinho, N; Goldman, I; Landau, S; Somberg, J; Tullo, NG	1
Birnbaumer, L; Hofmann, F; Ito, H; Klugbauer, N; Lacinová, L; Schuster, A	1
Dei, S; Gualtieri, F; Lemoine, H; Mannhold, R; Romanelli, MN; Teodori, E; Voigt, W	1
Frohlich, ED; Gossman, E; Oren, S	1
Godfraind, T; Morel, N; Salomone, S; Silva, CL	1
Hagiwara, M; Nagao, T; Shimasue, K; Urushidani, T	1
Luus, HG; Müller, FO; Müller, FR; Schall, R	1
Abu Khoudoud, OR; Bikhazi, AB; Bitar, KM; el-Kasti, MM; Ibrahim, MZ; Kreydiyyeh, SI; Saleh, RS	1
Adachi-Akahane, S; Hagiwara, M; Nagao, T	1
Ngan, ET; Vincent, SR	1
Bollo-Dragnic, S; Díaz-Araya, G; Letelier, ME; Marín-Catalán, R; Núñez-Vergara, LJ; Pino, L; Squella, JA	1
Ahmed, A; Kanaide, H; Kobayashi, S; Nishimura, J; Shikasho, T	1
Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H	1
Akkaya, V; Ark, E; Ecder, T; Sever, MS; Türk, S; Türkmen, A; Yildiz, A	1
Chan, L; Jacob, LP; Malhotra, D; Shapiro, JI	1
Borges, AC; Paiva, TB; Prioste, RN; Shimuta, SI	1
Aardal, S; Helle, KB; Lillestłl, IK	1
Bodi, I; Motoike, HK; Nakayama, H; Schwartz, A; Varadi, G	1
An, RH; Hofmann, F; Ito, H; Kass, RS; Klugbauer, N; Lacinová, L; Triggle, D; Xia, J	1
Marche, P; Stepien, O	1
Benquet, P; Frere, S; Pichon, Y; Tiaho, F	1
Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L	1
El Bardai, S; Hamaide, MC; Lyoussi, B; Morel, N; Quetin-Leclercq, J; Wibo, M	1
Hoda, JC; Huber, IG; Sinnegger-Brauns, MJ; Striessnig, J; Walter-Bastl, D; Wappl-Kornherr, E	1
Faverdin, C; Marche, P; Polidano, E; Yin, X	1
Prisant, LM; Spaulding, VC	1
Sahney, S	1
Fujino Oki, T; Kato, Y; Kurosawa, S; Nanri, M; Uchida, S; Yamada, S; Yoshida, K	1
Daschil, N; Humpel, C	1
Attenburrow, MJ; Cipriani, A; Geddes, JR; Harrison, PJ; Lane, TA; Panchal, P; Saunders, K; Stefaniak, J; Stockton, S; Tunbridge, EM	1

Reviews

5 review(s) available for isradipine and verapamil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New drugs for hypertension--variations on old themes. Drug and therapeutics bulletin, 1991, Mar-18, Volume: 29, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil	1991
Bioequivalence of controlled-release calcium antagonists. Clinical pharmacokinetics, 1997, Volume: 32, Issue:1 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Drugs, Generic; Humans; Isradipine; Therapeutic Equivalency; United States; United States Food and Drug Administration; Verapamil	1997
A review of calcium channel antagonists in the treatment of pediatric hypertension. Paediatric drugs, 2006, Volume: 8, Issue:6 Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipine; Nifedipine; Verapamil	2006
A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development. Molecular psychiatry, 2016, Volume: 21, Issue:10 Topics: Bipolar Disorder; Calcium Channel Blockers; Calcium Channels, L-Type; Double-Blind Method; Humans; Isradipine; Nimodipine; Verapamil	2016

Trials

6 trial(s) available for isradipine and verapamil

Article	Year
The comparative effects of verapamil and a new dihydropyridine calcium channel blocker on digoxin pharmacokinetics. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:1 Topics: Adolescent; Adult; Digoxin; Drug Interactions; Humans; Isradipine; Kinetics; Male; Pyridines; Random Allocation; Verapamil	1987
Comparative effects of verapamil and isradipine on steady-state digoxin kinetics. Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:6 Topics: Adult; Calcium Channel Blockers; Digoxin; Drug Interactions; Heart Rate; Humans; Isradipine; Male; Pyridines; Verapamil	1988
Immunosuppressive effects of different calcium channel blockers in human kidney allografts. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Calcium; Calcium Channel Blockers; Cyclosporine; Cytokines; Diltiazem; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isradipine; Kidney Transplantation; Lymphocytes; Prednisolone; Transplantation, Homologous; Verapamil	1995
A randomized comparative study of the electrophysiological and electrocardiographic effects of isradipine vs verapamil. Acta anaesthesiologica Scandinavica. Supplementum, 1993, Volume: 99 Topics: Adult; Aged; Aged, 80 and over; Electrocardiography; Electrophysiology; Female; Humans; Infusions, Intravenous; Isradipine; Male; Middle Aged; Verapamil	1993
Effects of calcium entry blockers on distribution of blood volume. American journal of hypertension, 1996, Volume: 9, Issue:7 Topics: Blood Volume; Calcium Channel Blockers; Diltiazem; Female; Head-Down Tilt; Hemodynamics; Humans; Isradipine; Male; Middle Aged; Posture; Vascular Capacitance; Vasoconstriction; Verapamil	1996
Interaction between cyclosporine A and verapamil, felodipine, and isradipine. Nephron, 1999, Volume: 81, Issue:1 Topics: Adult; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Felodipine; Female; Humans; Immunosuppressive Agents; Isradipine; Kidney Transplantation; Male; Verapamil	1999

Other Studies

84 other study(ies) available for isradipine and verapamil

Article	Year
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein. Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine	1992
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5 Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effects of diltiazem and verapamil on (+)-PN 200-110 binding kinetics in dog cardiac membranes. European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3 Topics: Allosteric Regulation; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dogs; Female; In Vitro Techniques; Isradipine; Kinetics; Male; Myocardium; Receptors, Nicotinic; Temperature; Verapamil	1992
Isradipine and other calcium channel antagonists attenuate ethanol consumption in ethanol-preferring rats. Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:3 Topics: Alcohol Drinking; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil	1992
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer. Molecular pharmacology, 1992, Volume: 41, Issue:2 Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil	1992
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140. The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17 Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil	1991
Role of calcium in regulation of phosphoinositide signaling pathway. Journal of molecular neuroscience : MN, 1991, Volume: 3, Issue:1 Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbachol; Cations, Divalent; Cells, Cultured; Cerebral Cortex; Diltiazem; Egtazic Acid; Inositol; Inositol Phosphates; Isradipine; Kinetics; Models, Neurological; Neurons; Oxadiazoles; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Signal Transduction; Sulfonamides; Verapamil	1991
Negative inotropic properties of isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardial tissue. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6 Topics: Adult; Aged; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Electric Stimulation; Female; Heart; Heart Diseases; Humans; In Vitro Techniques; Isradipine; Male; Middle Aged; Myocardial Contraction; Nifedipine; Papillary Muscles; Pyridines; Verapamil	1990
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system. Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil	1990
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations. Molecular pharmacology, 1991, Volume: 40, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Isradipine; Male; Myocardium; Potassium; Pyrroles; Radioligand Assay; Rats; Vasoconstriction; Verapamil	1991
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil	1991
Negative inotropic activity of the calcium antagonists isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardium. American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2 Topics: Antihypertensive Agents; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Heart Diseases; Humans; Hypertension; Isradipine; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Pyridines; Vasodilation; Verapamil	1991
Calcium ions inhibit the allosteric interaction between the dihydropyridine and phenylalkylamine binding site on the voltage-gated calcium channel in heart sarcolemma but not in skeletal muscle transverse tubules. Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:11 Topics: Allosteric Regulation; Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Heart; In Vitro Techniques; Isradipine; Kinetics; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Sarcolemma; Verapamil	1990
Calcium channel ligand binding to intact, concanavalin A and cyclic AMP-treated cells of the immune system. Immunology letters, 1990, Volume: 26, Issue:3 Topics: Animals; Bucladesine; Calcium Channels; Concanavalin A; Isradipine; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Mice, Inbred CBA; Nitrendipine; Oxadiazoles; Spleen; Verapamil	1990
Increase in [3H]PN 200-110 binding to cardiac muscle membrane in streptozocin-induced diabetic rats. Diabetes, 1990, Volume: 39, Issue:9 Topics: Animals; Binding Sites; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Isradipine; Male; Membranes; Myocardium; Oxadiazoles; Rats; Rats, Inbred Strains; Streptozocin; Tritium; Verapamil	1990
Different negative inotropic activity of Ca2(+)-antagonists in human myocardial tissue. Klinische Wochenschrift, 1990, Aug-17, Volume: 68, Issue:16 Topics: Calcium Channel Blockers; Depression, Chemical; Diltiazem; Heart Atria; Heart Failure; Heart Transplantation; Humans; Isradipine; Myocardial Contraction; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Verapamil	1990
SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2 Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Indolizines; Isradipine; Male; Myocardium; Oxadiazoles; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Sarcolemma; Verapamil	1990
Interactions of spironolactone with (+)-[3H]-isradipine and (-)-[3H]-desmethoxyverapamil binding sites in vascular smooth muscle. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Horses; In Vitro Techniques; Isradipine; Ligands; Muscle, Smooth, Vascular; Portal Vein; Progesterone; Pyridines; Spironolactone; Verapamil	1990
Calcium channel receptor sites for (+)-[3H]PN 200-110 in coronary artery. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Coronary Vessels; Diltiazem; Edetic Acid; Female; In Vitro Techniques; Isradipine; Kinetics; Male; Oxadiazoles; Receptors, Nicotinic; Swine; Verapamil	1990
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action. The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19 Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil	1990
Selective modulation by membrane potential of desmethoxyverapamil binding to calcium channels in rat portal vein. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3 Topics: Animals; Barium; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Isradipine; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Portal Vein; Pyridines; Rats; Strontium; Verapamil	1990
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations. Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3 Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil	1985
Dihydropyridine and peripheral type benzodiazepine binding sites: subcellular distribution and molecular size determination. European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3 Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dogs; Ion Channels; Isoquinolines; Isradipine; Male; Molecular Weight; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Verapamil	1985
Purified calcium channels have three allosterically coupled drug receptors. FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil	1986
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation. Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil	1986
The 165-kDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel. European journal of biochemistry, 1987, Aug-17, Volume: 167, Issue:1 Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Verapamil	1987
Effect of calcium channel modulators on isolated endothelial cells. Biochemical and biophysical research communications, 1988, Jul-29, Volume: 154, Issue:2 Topics: Adenosine Triphosphate; Animals; Benzofurans; Biological Products; Bradykinin; Calcium; Carbachol; Cattle; Diltiazem; Endothelium; Fura-2; Ion Channels; Isradipine; Nitric Oxide; Oxadiazoles; Thrombin; Verapamil	1988
Potential-dependent allosteric modulation of 1,4-dihydropyridine binding by d-(cis)-diltiazem and (+/-)-verapamil in living cardiac cells. Molecular pharmacology, 1988, Volume: 34, Issue:2 Topics: Allosteric Regulation; Animals; Calcium; Diltiazem; Heart; In Vitro Techniques; Ion Channels; Isradipine; Membrane Potentials; Myocardium; Oxadiazoles; Rats; Sarcolemma; Verapamil	1988
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function. Biochemistry, 1988, Jul-12, Volume: 27, Issue:14 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil	1988
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles. The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil	1989
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2 Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydropyridines; Indicators and Reagents; Isradipine; Male; Myocardium; Oxadiazoles; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Nicotinic; Time Factors; Verapamil	1989
Calcium blockers: antiatherogenic action by influencing the prostaglandin-system. Progress in clinical and biological research, 1989, Volume: 301 Topics: Adult; Animals; Arteriosclerosis; Calcium Channel Blockers; Diltiazem; Epoprostenol; Female; Humans; In Vitro Techniques; Isradipine; Male; Malondialdehyde; Nifedipine; Platelet Aggregation; Prostaglandins; Pyridines; Rats; Rats, Inbred Strains; Verapamil	1989
The failure of endothelin to displace bound, radioactively-labelled, calcium antagonists (PN 200/110, D888 and diltiazem). British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endothelins; Female; In Vitro Techniques; Isradipine; Oxadiazoles; Peptides; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil	1989
Is Ca2+ antagonists binding protein from cytosolic fraction the precursor of alpha 1-subunit of Ca2+ channel? General physiology and biophysics, 1989, Volume: 8, Issue:2 Topics: Affinity Labels; Animals; Antibodies; Azides; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cytoplasm; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Oxadiazoles; Protein Precursors; Rabbits; Radioligand Assay; Receptors, Nicotinic; Ultraviolet Rays; Verapamil	1989
Molecular approach to the calcium channel. Advances in myocardiology, 1985, Volume: 5 Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil	1985
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling. Biochemical and biophysical research communications, 1988, Nov-15, Volume: 156, Issue:3 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Isradipine; Mice; Muscle Contraction; Oxadiazoles; Piperidines; Thiazines; Verapamil	1988
Interaction between two calcium antagonists and two beta blockers in conscious rabbits: hemodynamic consequences of differing cardiodepressant properties. The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Consciousness; Drug Interactions; Hemodynamics; Humans; Isradipine; Oxadiazoles; Pindolol; Propranolol; Rabbits; Verapamil	1987
Cardioprotection by the calcium antagonist PN 200-110 in the absence and presence of cardiodepression. British journal of pharmacology, 1985, Volume: 86, Issue:1 Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; In Vitro Techniques; Isradipine; Myocardial Contraction; Myocardium; Oxadiazoles; Rabbits; Time Factors; Verapamil	1985
A nimodipine-resistant Ca2+ pathway is involved in myogenic tone in a resistance artery. The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 2 Topics: Analysis of Variance; Animals; Arteries; Calcium; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance; Isradipine; Male; Manganese; Muscle, Smooth, Vascular; Nicotinic Acids; Nimodipine; Oxadiazoles; Potassium; Rabbits; Vascular Resistance; Verapamil	1986
A novel high affinity class of Ca2+ channel blockers. Molecular pharmacology, 1988, Volume: 33, Issue:4 Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil	1988
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes. The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3 Topics: Affinity Labels; Animals; Autoradiography; Benzazepines; Bepridil; Binding, Competitive; Calcium Channels; Diltiazem; Isradipine; Kinetics; Muscles; Oxadiazoles; Photochemistry; Pyrrolidines; Rabbits; Receptors, Nicotinic; Verapamil	1986
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3 Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil	1986
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists. Biochemical and biophysical research communications, 1995, Aug-15, Volume: 213, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cadmium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Isradipine; Neuroblastoma; Neurons; Nicotine; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Receptors, Nicotinic; Spider Venoms; Tumor Cells, Cultured; Verapamil	1995
The block of the expressed L-type calcium channel is modulated by the beta 3 subunit. FEBS letters, 1995, Oct-09, Volume: 373, Issue:2 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; CHO Cells; Cricetinae; Feedback; Gallopamil; Gene Expression; Intracellular Membranes; Isradipine; Macromolecular Substances; Membrane Potentials; Mibefradil; Microsomes; Myocardium; Rabbits; Recombinant Proteins; Structure-Activity Relationship; Tetrahydronaphthalenes; Transfection; Verapamil	1995
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells. Neurochemical research, 1993, Volume: 18, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Bucladesine; Cell Differentiation; Cell Membrane; Diltiazem; Glioma; Hybrid Cells; Isradipine; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxin GVIA; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil	1993
Expression of the L-type calcium channel with two different beta subunits and its modulation by Ro 40-5967. Pflugers Archiv : European journal of physiology, 1995, Volume: 429, Issue:3 Topics: Animals; Antibodies, Monoclonal; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; CHO Cells; Cricetinae; Electrophysiology; Isradipine; Mibefradil; Muscle, Smooth; Stereoisomerism; Tetrahydronaphthalenes; Transfection; Verapamil	1995
T-tubule depolarization-induced SR Ca2+ release is controlled by dihydropyridine receptor- and Ca(2+)-dependent mechanisms in cell homogenates from rabbit skeletal muscle. The Journal of general physiology, 1995, Volume: 105, Issue:3 Topics: Animals; Calcium; Calcium Channels, L-Type; Egtazic Acid; Electrophysiology; Isradipine; Microtubules; Muscle Proteins; Muscle, Skeletal; Nifedipine; Rabbits; Sarcoplasmic Reticulum; Verapamil	1995
In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with alpha-tocopherol. Biochemical and biophysical research communications, 1994, Sep-30, Volume: 203, Issue:3 Topics: Adult; Amlodipine; Antioxidants; Calcium Channel Blockers; Copper; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; Isradipine; Lipoproteins, LDL; Oxidation-Reduction; Reference Values; Thiobarbituric Acid Reactive Substances; Verapamil; Vitamin E	1994
Effect of high-dose verapamil administration on the Ca2+ channel density in rat cardiac tissue. Pharmacology, 1994, Volume: 49, Issue:1 Topics: Animals; Calcium Channels; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Implants; Female; Heart Ventricles; Injections, Subcutaneous; Isradipine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Survival Rate; Verapamil	1994
Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels. European journal of pharmacology, 1994, Mar-15, Volume: 267, Issue:1 Topics: Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Rats; Receptors, Tachykinin; Verapamil	1994
Brain calcium channel related dihydropyridine and phenylalkylamine binding sites in Alzheimer's, Parkinson's and Huntington's diseases. Brain research, 1993, May-21, Volume: 611, Issue:2 Topics: Aged; Alzheimer Disease; Autopsy; Binding Sites; Brain; Calcium; Calcium Channels; Dihydropyridines; Female; Humans; Huntington Disease; Isradipine; Male; Middle Aged; Organ Specificity; Parkinson Disease; Reference Values; Verapamil	1993
The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines. The EMBO journal, 1996, May-15, Volume: 15, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Benzimidazoles; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Humans; Ion Channel Gating; Isradipine; Mibefradil; Molecular Sequence Data; Muscle Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Tetrahydronaphthalenes; Transfection; Verapamil	1996
Structural dependence of the allosteric interaction of semi-rigid verapamil analogues with dihydropyridine-binding in kitten heart. European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3 Topics: Allosteric Site; Animals; Calcium Channel Blockers; Cats; Isradipine; Models, Molecular; Myocardium; Structure-Activity Relationship; Verapamil	1995
Facilitation of the vasorelaxant action of calcium antagonists by basal nitric oxide in depolarized artery. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:4 Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Isradipine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Verapamil	1996
Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. European journal of pharmacology, 1996, Feb-05, Volume: 296, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endocannabinoids; Isradipine; Male; Polyunsaturated Alkamides; Rabbits; Verapamil	1996
Binding and distribution of three prototype calcium channel blockers in perfused rat liver. Molecular and cellular biochemistry, 1997, Volume: 169, Issue:1-2 Topics: Animals; Azides; Calcium Channel Blockers; Calcium Channels; Carbon Radioisotopes; Dihydropyridines; Inulin; Isradipine; Liver; Models, Biological; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Urea; Verapamil	1997
High-affinity binding of DTZ323, a novel derivative of diltiazem, to rabbit skeletal muscle L-type Ca++ channels. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Diltiazem; Isradipine; Male; Muscle, Skeletal; Rabbits; Verapamil	1997
Carbamazepine and L-type calcium channel inhibitors: a binding assay study. Biological psychiatry, 1996, Jun-01, Volume: 39, Issue:11 Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Calcium Channel Blockers; Carbamazepine; Diltiazem; In Vitro Techniques; Isradipine; Lithium; Male; Phenethylamines; Rats; Rats, Wistar; Verapamil	1996
Isradipine and lacidipine: effects in vivo and in vitro on Trypanosoma cruzi epimastigotes. General pharmacology, 1998, Volume: 30, Issue:1 Topics: Animals; Calcium Channel Blockers; Cattle; Dihydropyridines; Diltiazem; Isradipine; Oxygen Consumption; Trypanocidal Agents; Trypanosoma cruzi; Verapamil	1998
Differential effects of Ca2+ channel blockers on Ca2+ transients and cell cycle progression in vascular smooth muscle cells. European journal of pharmacology, 1998, Mar-05, Volume: 344, Issue:2-3 Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Isradipine; Male; Muscle, Smooth, Vascular; Nickel; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Verapamil	1998
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil	1998
Absence of a dose-response of cyclosporine levels to clinically used doses of diltiazem and verapamil. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:2 Topics: Administration, Oral; Calcium Channel Blockers; Cyclosporine; Diltiazem; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Isradipine; Medical Records; Nifedipine; Radioimmunoassay; Retrospective Studies; Verapamil	1999
Different pathways for Ca2+ mobilization by angiotensin II and carbachol in the circular muscle of the guinea-pig ileum. European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Isradipine; Losartan; Male; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nickel; Nifedipine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Vasoconstrictor Agents; Verapamil	1999
Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery. Scandinavian journal of clinical and laboratory investigation, 1998, Volume: 58, Issue:8 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isradipine; Milrinone; Muscle, Smooth, Vascular; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Rolipram; Swine; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilation; Verapamil; Vinca Alkaloids	1998
A region in IVS5 of the human cardiac L-type calcium channel is required for the use-dependent block by phenylalkylamines and benzothiazepines. The Journal of biological chemistry, 1999, Apr-02, Volume: 274, Issue:14 Topics: Amino Acid Sequence; Animals; Barium; Calcium Channels; Calcium Channels, L-Type; Humans; Isradipine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Oocytes; Rats; Sodium Channels; Structure-Activity Relationship; Verapamil; Xenopus	1999
Distinctions in the molecular determinants of charged and neutral dihydropyridine block of L-type calcium channels. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Amino Acid Sequence; Amino Acid Substitution; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Humans; Isradipine; Kinetics; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Structure, Secondary; Recombinant Fusion Proteins; Recombinant Proteins; Threonine; Transfection; Tyrosine; Verapamil	1999
Amlodipine inhibits thapsigargin-sensitive CA(2+) stores in thrombin-stimulated vascular smooth muscle cells. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:3 Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Intracellular Fluid; Isradipine; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Inbred WKY; Sarcoplasmic Reticulum; Signal Transduction; Thapsigargin; Thrombin; Verapamil	2000
Properties and development of calcium currents in embryonic cockroach neurons. Neuroscience letters, 2000, Nov-10, Volume: 294, Issue:1 Topics: Amiloride; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; In Vitro Techniques; Isradipine; Membrane Potentials; Mibefradil; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Periplaneta; Verapamil	2000
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture. American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil	2001
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel. European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3 Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diterpenes; Furans; Ileum; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Vasodilator Agents; Verapamil	2004
Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels. The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53 Topics: Animals; Brain; Calcium; Calcium Channels; Calcium Channels, L-Type; Carrier Proteins; Cell Membrane; Dihydropyridines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Gallopamil; Homozygote; In Situ Hybridization; Isradipine; Kinetics; Mice; Mice, Transgenic; Microsomes; Models, Biological; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Complementary; Steroid Isomerases; Tyrosine; Verapamil; Xenopus laevis	2004
Role of L-type calcium channel blocking in epidermal growth factor receptor-independent activation of extracellular signal regulated kinase 1/2. Journal of hypertension, 2005, Volume: 23, Issue:2 Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; ErbB Receptors; Isradipine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thrombin; Verapamil	2005
Antihypertensive pharmacobezoar. Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:4 Topics: Antihypertensive Agents; Bezoars; Calcium Channel Blockers; Drug Delivery Systems; Gastrointestinal Diseases; Humans; Isradipine; Nifedipine; Postoperative Complications; Tablets; Verapamil	2006
Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain. Life sciences, 2007, Jun-06, Volume: 80, Issue:26 Topics: Analysis of Variance; Animals; Benzilates; Brain; Calcium Channels, L-Type; Diltiazem; Isradipine; Male; Mandelic Acids; N-Methylscopolamine; Protein Binding; Rats; Rats, Sprague-Dawley; Tritium; Urinary Bladder; Verapamil	2007
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses. Brain research, 2014, Sep-18, Volume: 1581 Topics: Animals; Axotomy; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cholinergic Neurons; Dopaminergic Neurons; Isradipine; Neuroimmunomodulation; Neuroprotective Agents; Nicardipine; Nifedipine; Nimodipine; Rats, Sprague-Dawley; Substantia Nigra; Tissue Culture Techniques; Ventral Tegmental Area; Verapamil	2014