isradipine has been researched along with prazosin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hill, SJ; Kendall, DA; Ruck, A | 1 |
| Gonasun, LM; McAllister, RG; Swartz, SL; Thadani, U | 1 |
| Nahorski, SR; Rooney, TA | 1 |
| Jie, K; Thoolen, MJ; Timmermans, PB; van Brummelen, P; van Zwieten, PA | 1 |
| Hamilton, BP | 1 |
| Ishiguro, S; Miyamoto, A; Nishio, A; Sakaguchi, H | 1 |
| Abe, M; Ito, Y; Oki-Fujino, T; Oyunzul, L; Yamada, S | 1 |
2 review(s) available for isradipine and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil | 1991 |
2 trial(s) available for isradipine and prazosin
| Article | Year |
|---|---|
A multicenter comparison of isradipine and prazosin for treatment of essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Heart Rate; Humans; Isradipine; Middle Aged; Prazosin; Pyridines | 1990 |
Treatment of essential hypertension with PN 200-110 (isradipine).
Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Oxadiazoles; Prazosin; Propranolol; Random Allocation; Time Factors | 1987 |
13 other study(ies) available for isradipine and prazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Alpha- and beta-adrenoceptor regulation of cyclic AMP accumulation in cultured rat astrocytes. A comparison of primary protoplasmic and mixed fibrous/protoplasmic astroglial cultures.
Topics: Adrenergic Antagonists; Animals; Astrocytes; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Isradipine; Microscopy, Phase-Contrast; Norepinephrine; Phentolamine; Prazosin; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1991 |
Regional characterization of agonist and depolarization-induced phosphoinositide hydrolysis in rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Brain; Calcium Channel Blockers; Carbachol; Hydrolysis; Isradipine; Male; Norepinephrine; Oxadiazoles; Phosphatidylinositols; Physostigmine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Muscarinic; Tissue Distribution | 1986 |
Effects of PN 200-110, a new calcium antagonist, on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction elicited by selective alpha-adrenoceptor agonists and catecholamines in the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Catecholamines; Decerebrate State; Epinephrine; Imidazoles; Isradipine; Male; Norepinephrine; Oxadiazoles; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1985 |
Enhanced contractile response to phenylephrine and increased density of [3H]PN200-110 binding sites in thoracic aorta isolated from dietary magnesium-deficient rats.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Diet; Endothelium, Vascular; Isradipine; Magnesium Deficiency; Male; Muscle Contraction; Nifedipine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Pharmacologically relevant receptor binding characteristics and 5alpha-reductase inhibitory activity of free Fatty acids contained in saw palmetto extract.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Fatty Acids, Nonesterified; Female; Isradipine; Liver; Male; Microsomes, Liver; Muscarinic Agonists; N-Methylscopolamine; Plant Extracts; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Muscarinic; Serenoa | 2009 |