isradipine has been researched along with metoprolol in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bräutigam, M; Rüddel, H; Schächinger, H; Schmieder, R; Schulte, W; Welzel, D | 1 |
| Ekman, K; Harjula, K; Hartikainen, M; Helin, M; Inkovaara, J; Kataja, M; Luomanmäki, K; Viikari, J | 1 |
| Rockstroh, J; Rüddel, H; Schächinger, H; Schlebusch, H; Schmieder, RE; Schulte, W | 1 |
| Erkinjuntti, M; Kantola, I; Mansury, L; Rauhala, E | 1 |
| Christensen, KL | 1 |
| Christensen, KL; Jespersen, LT; Mulvany, MJ | 1 |
| Baandrup, U; Christensen, HR; Christensen, KL; Jespersen, LT; Nielsen, H | 1 |
| Bräutigam, M; Burger, KJ; Del Pino, M; Levenson, J; Merli, I; Simon, A; Welzel, D | 1 |
| Brautigam, M; Del Pino, M; Levenson, J; Merli, I; Simon, A; Welzel, D | 1 |
| Gatzka, C; Rüddel, H; Schächinger, H; Schmieder, RE; Schobel, H | 1 |
| Cacciatore, B; Kaaja, RJ; Laakso, M; Laivuori, HM; Tikkanen, MJ; Ylikorkala, RO | 1 |
1 review(s) available for isradipine and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
8 trial(s) available for isradipine and metoprolol
| Article | Year |
|---|---|
Pharmacological modulation of stress-induced cardiovascular hyperreactivity in essential hypertension.
Topics: Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Hemodynamics; Humans; Hypertension; Isradipine; Male; Metoprolol; Stress, Psychological | 1992 |
Efficacy and tolerability of isradipine and metoprolol in treatment of hypertension: the Finnish Isradipine Study in Hypertension (FISH).
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Hypertension; Isradipine; Male; Metoprolol; Middle Aged | 1992 |
Impact of antihypertensive therapy with isradipine and metoprolol on early markers of hypertensive nephropathy.
Topics: Antihypertensive Agents; Dihydropyridines; Double-Blind Method; Humans; Hypertension; Isradipine; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Proteinuria | 1992 |
Sleep disturbances in hypertension: a double-blind study between isradipine and metoprolol.
Topics: Adult; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Humans; Hypertension; Isradipine; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Respiration; Sleep Apnea Syndromes; Snoring | 1991 |
[Vasoselective, substance-specific actions of isradipine on the great arteries of hypertensives in comparison to metoprolol].
Topics: Adult; Aged; Arteries; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Isradipine; Male; Metoprolol; Middle Aged; Ultrasonography; Vascular Resistance | 1994 |
Intrinsic effect of antihypertensive treatment with isradipine and metoprolol on large artery geometric and elastic properties.
Topics: Adult; Aged; Blood Pressure; Brachial Artery; Compliance; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Isradipine; Male; Metoprolol; Middle Aged; Vascular Resistance | 1993 |
Obesity as a determinant for response to antihypertensive treatment.
Topics: Blood Pressure; Body Mass Index; Double-Blind Method; Humans; Hypertension; Isradipine; Male; Metoprolol; Middle Aged; Obesity | 1993 |
Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Glucose; Humans; Insulin; Isradipine; Lipids; Lipoproteins; Metoprolol; Pre-Eclampsia; Pregnancy; Prospective Studies; Umbilical Arteries | 1999 |
11 other study(ies) available for isradipine and metoprolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Reducing pulse pressure in hypertension may normalize small artery structure.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; Hydralazine; Hypertension; Indoles; Isradipine; Male; Metoprolol; Perindopril; Pulse; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis | 1991 |
Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hydralazine; Hypertension; Indoles; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; Metoprolol; Perindopril; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1989 |
Antitrophic properties of antihypertensive drugs may depend solely on their blood pressure-lowering capability. A comparative study of isradipine, hydralazine, and metoprolol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Coronary Vessels; Hydralazine; Isradipine; Male; Metoprolol; Pyridines; Rats; Rats, Inbred SHR; Vascular Resistance | 1989 |